Neoplasm refers to abnormal cell growth and can be benign (non-cancerous) or malignant (cancerous). Benign tumors are self-limited and do not invade other tissues, while malignant tumors are characterized by uncontrolled growth and invasion. Oncology is the study of tumors. Tumors are classified based on their tissue of origin and behavior. The key differences between benign and malignant tumors are size, growth rate, invasion of surrounding tissues, spread to distant sites, and whether they recur after removal.
Neoplasm refers to abnormal cell growth and can be benign (non-cancerous) or malignant (cancerous). Benign tumors are self-limited and do not invade other tissues, while malignant tumors are characterized by uncontrolled growth and invasion. Oncology is the study of tumors. Tumors are classified based on their tissue of origin and behavior. The key differences between benign and malignant tumors are size, growth rate, invasion of surrounding tissues, spread to distant sites, and whether they recur after removal.
Neoplasm refers to abnormal cell growth and can be benign (non-cancerous) or malignant (cancerous). Benign tumors are self-limited and do not invade other tissues, while malignant tumors are characterized by uncontrolled growth and invasion. Oncology is the study of tumors. Tumors are classified based on their tissue of origin and behavior. The key differences between benign and malignant tumors are size, growth rate, invasion of surrounding tissues, spread to distant sites, and whether they recur after removal.
Neoplasm comes from the word neoplasia that means new growth.
The term neoplasia refers to a mass that has developed due to
abnormal cell or tissue growth.
Neoplasm can be define as a new growth of tissue characterized by
progressive, uncontrolled proliferation of cells. generally word neoplasm is known as tumour.
Oncology : Oncology is the study of tumour or neoplasm. Greek
“oncos” means tumour.
Classification:
Histogenetic:
1. Tumour of epithelial tissue origin.
2. Tumour of connective tissue origin.
Behavioural Type:
1.BenignTumour: They do not invade surrounding or remote tissue.
2.Malignent tumour: Always invade the surrounding or remote
tissue.Generally word these are known as cancer.
3.Latent Cancer: Cell of these neoplasm shows features of malignant
tumour but clinically silent. e.g. prostate cancer of elderly man. Benign Tumour: Benign neoplasm are those neoplasm which do not invade surrounding or remote tissue. Generally the suffix “oma” denotes benign neoplasm; e.g. adenoma means benign tumour of epithelial cell.
Characteristics of benign tumour:
1. Generally small in size.
2. Within a capsule. 3. No local invasion. 4. Slow Growth. 5. No variation of tumour cell morphology. 6. Tumour cells are similar to the cells of tissue origin. 7. Nucleus is similar in size and nucleus cytoplasm ratio is normal(1:4 to 1:6) 8. No spreadign to remote tissue. 9. Generally no recurrence after complete removal. 10. Generally not fatal.
Malignant Tumour: Malignant neoplasm are those neoplasm which
invade surrounding or remote tissues. In common word malignent tumour are known as cancer. Suffix “carcinoma” “Sarcoma” “blastoma” denotes malignant tumour. E.g. adenocarcinoma means malignant tumour of epithelial cell.
sarcoma: Generally malignant tumour of soft tissue are expressed by
sarcoma.
Carcinoma: Generally malignant tumour of epithelium tissue are
expressed by carcinoma.
Characteristics of malignant tumour:
1. Generally large in size. 2. Local invasion is one of the main characteristics. 3. Rapid growth. 4. Neoplasms cells are not similar to the cell of tissue origin. 5. Variation in tumour cell morphology. 6. Nucleus size is variate. 7. Nucleus and cytoplasm ratio is abnormal.(May be 1:1). 8. Generally spread to remote tissue. 9. Recurrence after complete removal can be found. 10. Almost fatal.
Different between benign and malignanttumour:
Benign neoplasm Malignant neoplasm
Generally small Generally Large Slow Growth Rapid Growth Possess a capsule No capsule. No local invasion. Local invasion present. Similar to the cell of origin tissue. Not similar. No variation of tumour cell Present variation of tumour cell morphology. morphology. Nucleus size is similar. Not similar Nucleus cytoplasm ratio Nucleus cytoplasm ratio normal(1:4 to 1:6) Increased(may be 1:1) Generally no recurrent after May recurrent even after complete complete removal. removal. Metastasis absent. Must metastasis. Usually not fatal. Fatal.
Metastasis:Metastasis means transport of malignant cells to remote
from its origin and invation of the tissue at transported site. Carcinogen: Any kind of agent that can produce any type of tumour. Such as: Radiation,Nicotine,papiloma virus etc.