Differential Changes in Quitting Smoking by Daily Cigarette Co 2020 Drug and

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Drug and Alcohol Dependence 213 (2020) 108085

Contents lists available at ScienceDirect

Drug and Alcohol Dependence


journal homepage: www.elsevier.com/locate/drugalcdep

Differential changes in quitting smoking by daily cigarette consumption and T


intention to quit after the introduction of a tobacco tax increase and pictorial
cigarette pack warnings in Korea, 2013–2017
Ikhan Kima,b,*, Young-Ho Khangb,c
a
Department of Health Policy and Management, Jeju National University College of Medicine and Graduate School of Medicine, Jeju, Republic of Korea
b
Department of Health Policy and Management, Seoul National University College of Medicine, Seoul, Republic of Korea
c
Institute of Health Policy and Management, Seoul National University Medical Research Center, Seoul, Republic of Korea

A R T I C LE I N FO A B S T R A C T

Keywords: Background: : This study examined whether changes in quitting smoking differed according to smokers’ cigar-
Behavior ettes consumed per day (CPD) and intention to quit (ITQ) after the introduction of two tobacco control measures
Addictive in Korea, a tobacco tax increase in 2015 and pictorial cigarette pack warnings (PCW) in 2016.
Intention Methods: : We utilized data from the Korea Welfare Panel Study from 2013 to 2017, an interval that was divided
Smoking
into four periods (2013–2014, 2014–2015, 2015–2016, and 2016–2017). We examined differential changes in
Smoking cessation
Tobacco
quitting smoking by smokers’ CPD and ITQ using a generalized estimating equation model.
Republic of Korea Results: : Smokers with 1–14 CPD or an ITQ were more likely to quit smoking in each period. However, when
compared to the pre-policy period (2013–2014), smokers with 15 or more CPD and those with an ITQ had a
higher risk ratio of quitting smoking in all study periods. In stratified analyses, when the tobacco excise tax was
increased, the risk ratios of quitting smoking increased in most subgroups, especially smokers with 15 or more
CPD or an ITQ. The increased risk ratio of 15 or more CPD smokers subgroup sustained afterward. However,
after the introduction of PCW, there were no significant changes from the previous period in most subgroups.
Conclusions: : The addictive nature of tobacco and the type of tobacco control policies jointly contributed to
changes in quitting smoking among Korean smokers. Tobacco control policies, particularly substantial tobacco
tax increase, acted as a cue-to-action for quitting smoking among more dependent smokers.

1. Introduction tobacco smoking (Park et al., 2014).


Smoking has an addictive nature, as manifested by patterns of re-
Tobacco use is one of the most critical public health concerns in the inforcement, tolerance, and withdrawal symptoms (US Department of
world. Globally, tobacco use accounts for more than 7 million deaths Health and Human Services, 1988; Suranovic et al., 1999; Giovino
each year (World Health Organization, 2017; GBD 2017 Risk Factor et al., 1995). The costs of reducing cigarette consumption or quitting
Collaborators, 2018). In 2017, tobacco was the second leading risk are expected to be especially high for addicted smokers (Suranovic
factor of all-cause mortality for both sexes combined and the most et al., 1999; Chaloupka and Warner, 2000). When heavy smokers try to
harmful risk factor for men (GBD 2017 Risk Factor Collaborators, stop smoking, they experience withdrawal symptoms (both physical
2018). Smoking is known to be related to a broad array of diseases, and psychological), as well as interference with social interactions with
including cancer, heart disease, and respiratory diseases (Warren et al., their peer group (Thompson et al., 2003). Consequently, smoking de-
2014). Korea is no exception to the trend of tobacco being a significant pendence has shown an inverse relationship with future attempts to
risk factor for mortality and morbidity. In 2015, smoking was found to quit and with successfully quitting, and exhibited stronger direct as-
be the risk factor that accounted for the second-highest amount of sociations with quitting behavior than smokers’ social and demographic
disability-adjusted life years for both sexes combined in Korea (GBD characteristics (Hyland et al., 2006; Goldberg et al., 1993). According
2015 Risk Factors Collaborators, 2016). A previous study estimated that to a review by Vangeli et al., intention to quit (ITQ) smoking con-
one-third of all cancer deaths in Korean men could be attributed to sistently predicted attempts to quit, and dependence on tobacco was


Corresponding author at: Department of Health Policy and Management, Jeju National University College of Medicine and Graduate School of Medicine, 102
Jejudaehak-ro, Jeju-si, Jeju-do 63243, Republic of Korea.
E-mail address: ikhan.kim@jejunu.ac.kr (I. Kim).

https://doi.org/10.1016/j.drugalcdep.2020.108085
Received 21 January 2020; Received in revised form 27 April 2020; Accepted 9 May 2020
Available online 25 May 2020
0376-8716/ © 2020 Elsevier B.V. All rights reserved.
I. Kim and Y.-H. Khang Drug and Alcohol Dependence 213 (2020) 108085

inversely related to successfully quitting smoking (Vangeli et al., 2011). never been married, and had a relatively low ITQ and low secondhand
The effects of tobacco control policies also varied depending on smo- smoke (SHS) exposure. However, the difference in CPD between the
kers’ smoking dependence and motivation to quit (Suranovic et al., included and excluded samples was not significant (see Supplementary
1999; Willemsen, 2005; Hammond et al., 2003; Ross et al., 2011; Park Table 1). When we set the outcome variable as exclusion from the
et al., 2015; Tabuchi et al., 2017; Nagelhout et al., 2013; Levy et al., analytic sample and conducted a logistic regression analysis, SHS ex-
2007). posure, gender, marital status (never married vs. married or coha-
The Korean government recently introduced two new national-level biting), and self-rated health showed statistically significant differ-
tobacco control policies sequentially. The first policy that was in- ences, but CPD and ITQ were not significantly different. We conducted
troduced was an increase in the tobacco excise tax. The excise tax for a sensitivity analysis of all the 14,481 participants who participated in
one pack of cigarettes (20 cigarettes) in Korea increased by 2000 KRW the eighth survey, including a dummy variable that indicated their
in January 2015 (equivalent to 1.82 US dollars at the time). As a result, exclusion status. More details about the sensitivity analysis are de-
the price per pack of most brands of cigarettes increased from around scribed in the statistical analysis section.
2500 KRW to 4500 KRW (an 80% increase). The next policy, im-
plemented in December 2016, was the application of pictorial cigarette 2.2. Outcome variables
pack warnings (PCW) on the front and back of cigarette packs. Before
the introduction of this policy, cigarette pack warnings were configured In this study, the experience of quitting smoking was set as an
to cover 30% of cigarette packs and were text-only. However, since the outcome variable. Quitting smoking during a certain period was de-
policy has been introduced, more than 50% of each cigarette pack is fined as occurring when a person answered ‘yes’ to the question “do you
covered with a warning picture (30%) and a warning phrase (20%). The currently smoke?” on the baseline survey for each period and answered
warning pictures consisted of five pictures related to the specific disease ‘no’ to a question on the next wave survey.
(lung cancer, larynx cancer, oral cancer, heart disease, and stroke) and
other five pictures not directly related to the specific disease (second- 2.3. Smoking dependence and ITQ
hand smoke, premature death, skin aging, smoking during pregnancy,
and sexual dysfunction). An example of a warning phrase is “Smoking is Cigarettes per day (CPD) and ITQ were the independent variables of
the cause of lung cancer—do you still smoke?” along with information interest. CPD was measured by the question, “How many cigarettes a
on a smoking cessation hotline. day do you smoke on average?” We classified the responses as 1–14 and
Each of the two tobacco control policies was intended to affect 15 or more and set CPD as a categorical variable. This classification has
quitting behavior through different mechanisms. Tobacco tax increases also been adopted in previous studies to define smokers who are highly
aggravate the economic burden on current smokers, reducing the pre- dependent on smoking (Ip et al., 2012; Costa et al., 2010). Supple-
sent net utility of current smoking, while PCW initiates a cognitive and mentary Fig. 1 presents the distribution of current smokers’ daily ci-
emotional process by providing information about the negative con- garette consumption in 2013. Smokers who consumed half or one pack
sequences of smoking (Chaloupka and Warner, 2000; Thrasher et al., a day accounted for the largest proportion. In the sensitivity analysis,
2019; Hammond, 2011; Noar et al., 2016). In this study, we aimed to we further divided moderate to heavy smokers into those with 15–24
analyze differential changes in quitting smoking after the two tobacco and 25 + CPD and traced their changes in quitting behavior during the
control measures in different subgroups of smokers. study period. We defined those who answered that they “currently
[had] no plan to quit smoking,” or planned to quit smoking “not within
2. Material and methods six months, but someday” as having no ITQ (Maibach and Cotton, 1995;
Kale et al., 2015). Subjects who replied that they planned to quit
2.1. Data smoking “within a month” or “within six months” were defined as
having ITQ. In the sensitivity analysis, we did not further categorize
Data from the eighth through 12th surveys of the Korea Welfare these four answers and analyzed the incidence of quitting smoking and
Panel Study (KWPS) were used for analysis. The KWPS is a nationally attempting to quit in each period in each of those four groups.
representative panel survey that has been conducted annually since
2006. The KWPS survey sampled household panels across the country 2.4. Other explanatory variables
using a stratified sampling method and constructed a total of 7072
household panels in 2006. The KWPS originally assigned approximately We selected covariates with reference to the results of previous
50% of the total sample to low-income (less than 60% of median in- studies of predictors of attempts to quit and successfully quitting, as
come) participants, taking into account the sample attrition and survey well as smoking prevalence in Korea (Vangeli et al., 2011; Tabuchi
purposes (Korean Welfare Panel Study, 2020). 1800 new sample et al., 2017; Kim et al., 2017). The following nine characteristics of
households were replenished at the 7th survey in 2012 due to sample smokers were used as covariates: SHS exposure, gender, age, education
attrition. The original sample households that were completed the level, household income, marital status, self-rated health, alcohol con-
questionnaire in the 12th survey were 4398 (62.2%) households, and sumption, and residence. A detailed description of the explanatory
1500 (83.3%) households were completed among the replenished parameters is given in the Supplementary Material.
households in the 7th survey. The sample retention rate from the 8th to
the 12th survey used in this study was 86.8% (Korean Welfare Panel 2.5. Statistical analysis
Study, 2020). Well-trained interviewers visited each household and
interviewed the subjects face-to-face using a computer-assisted personal Since the tobacco tax increase and PCW were introduced nation-
interviewing method. Surveys were conducted between March and wide in Korea, all smokers were assumed to be exposed to the newly
June of each year. The analytic sample was structured as a balanced introduced tobacco control policies. The entire time interval covered by
panel of participants in the eighth (2013) survey. We initially analyzed the study (from 2013 to 2017) was divided into four periods
11,449 (79.1%) of the 14,481 participants aged 20 years or older who (2013–2014, 2014–2015, 2015–2016, and 2016–2017). This study used
participated in the eighth survey and were observed every year. Then, a discrete-time design to reflect the dynamic nature of smoking beha-
1239 participants who had any missing information were also excluded vior (Singer and Willet, 2003), as has been done to analyze the asso-
from the analysis. Finally, 10,210 (70.5%) participants were included in ciation between tobacco control policies and quitting behavior in pre-
the analytic sample. The excluded sample had a predominance of par- vious studies (Tabuchi et al., 2017; Nagelhout et al., 2013). The
ticipants who were male, younger, had a low educational level, had population at risk for quitting smoking between the kth and (k+1)th

2
I. Kim and Y.-H. Khang Drug and Alcohol Dependence 213 (2020) 108085

surveys was composed of those who were current smokers at the kth Table 1
baseline survey. Smokers who quit smoking in the previous period were The number of total study subjects during the entire study period and the
not included in the risk set for the following period, but participants number and characteristics of current smokers in the baseline year of each
who relapsed after quitting were included again in the risk set for that period.
period. This research design allowed us to deal with relapse of smoking Variables Baseline year
in the same participants over multiple periods.
We constructed a generalized estimating equation (GEE) log-bino- 2013 2014 2015 2016 2017

mial model without an intercept, taking into account the correlations of Total no. of participants 10,210
the observations (Hubbard et al., 2010; McNutt et al., 2003). The No. of current smokers 1803 1765 1553 1577 1528
reason for no intercept was to show the difference in quitting smoking (%) (17.7) (17.3) (15.2) (15.4) (15.0)
among the smoker subgroup for each discrete period. We added a Characteristics of current smokers
CPD, cigarettes 15.7 15.6 14.6 14.8 14.7
period dummy variable indicating for each period in the model. To
CPD < 15, % 44.7 44.6 49.3 49.3 50.0
calculate the reaction of the subset of smokers in each period, we added 15≤CPD, % 55.4 55.4 50.7 50.7 50.0
interaction terms for all dummy variables in a period and all ex- Having no ITQ, % 93.5 94.3 88.2 92.7 92.7
planatory variables to the model. This model assumes a different out- Plan to quit within a 2.7 1.9 3.8 2.1 2.1
month
come pattern for each period. We used the equation below.
Plan to quit within six 3.8 3.8 8.0 5.2 5.2
4 4 4 4
months
Not within six 41.8 34.5 42.8 37.9 41.4
ln(p) = ∑ αt Dit + ∑ β1t CPDit ∙Dit + ∑ β2t ITQit ∙Dit + ∑ βt Xit ∙Dit months, but someday
t=1 t=1 t=1 t=1
Currently no plans to 51.6 59.8 45.5 54.9 51.3
quit smoking
Where D represents each period within the time interval covered by the SHS, % 41.4 38.1 37.4 38.9 33.1
study; CPD was 0 when the smoker consumed less than 15 cigarettes Female gender, % 10.1 9.4 9.4 10.1 10.2
per day, otherwise 1; ITQ was 0 when the smoker had no intention to Mean age, year (SD) 51.2 51.8 52.0 53.1 53.6
(14.9) (15.0) (14.8) (14.8) (14.8)
quit, otherwise 1; X is a vector for other explanatory variables.
Education, %
We checked our model for multicollinearity using Pearson correla- Middle school or less 28.6 30.0 30.9 30.6 31.4
tion coefficients among all explanatory variables, and tolerance and VIF High school 39.0 39.0 39.6 39.1 39.3
value of each explanatory variable. When we calculated the magnitude College or more 32.4 31.1 29.5 30.3 29.3
of the correlation, we found that none of the variables exceeded the Income, %
More than 60% of 71.4 73.2 74.9 75.5 74.9
0.8–0.9 Pearson correlation coefficient, which is considered as the
median income
threshold at which multicollinearity possibly present (Midi et al., Less than 60% of 28.6 26.8 25.1 24.5 25.1
2013). When we calculated the tolerance and VIF, we found that two median income
variables, the age group of more than 70 (2.75), middle school or less Marital status, %
Married or cohabiting 65.2 65.7 64.3 64.4 64.4
education (2.58), had more than 2.5 of VIF. However, those were more
Divorced, widowed or 17.6 17.7 18.9 19.2 19.6
than 0.3 of the tolerance value. Besides, the variables of our main in- bereaved
terest, 15 or more CPD (1.14) and having no ITQ (1.02), did not in- Never married 17.2 16.6 16.8 16.4 16.0
dicate a potential collinearity problem. Self-rated health, %
The following two analyses were performed to examine whether Very good/Good/ 82.7 84.8 85.6 84.7 83.8
Normal
differences in smoker subgroups were associated with the introduction
Very poor/Poor 17.3 15.2 14.4 15.3 16.2
of tobacco control policies. First, we analyzed the magnitude of the Alcohol consumption, %
interactions of each study period with CPD and ITQ as of 2013–2014 Never drinker 23.2 24.0 26.0 26.0 24.7
using a GEE log-binomial model with an intercept. The regression also 1−4 times per month 33.0 32.7 29.7 30.1 30.0
2−3 times per week 26.3 26.6 27.4 24.9 25.3
contained the set of interaction terms between all the explanatory
4 or more times per 17.4 16.8 17.0 19.0 20.1
variables and the dummy variables for each period. This model ex- week
amined whether the behavioral differences according to CPD and ITQ in Residence, %
each period differed from the behavioral differences according to CPD Metropolitan 43.0 43.2 43.7 42.9 43.5
and ITQ in 2013–2014. Second, we conducted stratified analyses by Urban 38.8 39.1 39.3 39.6 40.1
Rural 18.2 17.7 16.9 17.5 16.5
CPD and ITQ. This model examined whether there were changes in
behavior as of 2013–2014 within each category of CPD and ITQ. All Notes. CPD = Cigarettes consumed per day; ITQ = Intention to quit; SD =
explanatory variables were adjusted. Standard deviation; SHS = Secondhand smoke.
We conducted two sensitivity analyses. The definition of heavy The tobacco tax increase policy was introduced in January 2015, and the PCW
smokers and smokers with an ITQ used in this study was arbitrary was introduced in December 2016.
(Tabuchi et al., 2017; Kale et al., 2015; Dijkstra et al., 1998). Thus, we
plotted the quitting behavior of the heaviest smokers (25 + CPD) 2.6. Ethics statement
during the study period. We also plotted the changes in quitting
smoking for each of the four responses to the ITQ question without This study was reviewed and approved by the Seoul National
further categorization. Second, we constructed a sample containing all University Institutional Review Board (IRB no. 1804-001-932).
2013 survey participants and performed the analysis including a
dummy variable indicating exclusion from the sample. SAS version 9.4
(SAS Institute Inc., Cary, NC, USA) was used for the analysis. The 3. Results
procedure used was PROC GEE, and we assumed an unstructured
covariance structure type as a working correlation matrix. The reason Table 1 shows the number of total observations and current smokers
for using the unstructured covariance structure type was that it had a in the baseline year, and the characteristics of current smokers. A total
unique value on each variance. of 10,210 subjects were followed up for five years. The number of
current smokers in the sample gradually decreased from 1803 in 2013
to 1528 in 2017. CPD declined after the introduction of the tobacco tax
increase (15.6–14.6). However, there was little change in the rest of the

3
I. Kim and Y.-H. Khang Drug and Alcohol Dependence 213 (2020) 108085

period except the period when tobacco taxes were substantially in- and ITQ. All changes tended to be higher in smokers with more than 15
creased. The proportion of smokers who smoked 15 or more CPD CPD. Smokers with an ITQ were more likely to stop smoking than in the
ranged from 50.0% to 55.4%. The steepest decrease in this proportion, 2013–2014 period. All the results were not statistically significant, al-
from 55.4% to 50.7%, was found between 2014 and 2015. The number though smokers with 15 + CPD showed marginally more quit smoking
of participants with no ITQ decreased in 2015 when the cigarette tax in 2014–2015 than smokers with less than 15 CPD (adjusted risk ratio:
was significantly increased, and then rose again in 2016 and 2017. 1.40; 95% CI (0.99, 1.98)). As of 2015–2016 period, both smokers with
Among current smokers, those with high school-level education, those 15 + CPD (adjusted risk ratio: 1.07; 95% CI (0.74, 1.55)) and an ITQ
who were married or cohabiting, those who consumed alcohol 1–4 (adjusted risk ratio: 1.08; 95% CI (0.77, 1.52)) did not show meaningful
times a month, and those living in metropolitan areas accounted for the interaction with the introduction of PCW.
highest proportion across the study period. The dynamics of partici- Fig. 2 shows the stratified analyses by CPD and ITQ subgroups on
pants’ smoking and non-smoking status during the entire study period quitting. These results present the change in quitting smoking in each
are shown in < Supplementary Fig. 2 > . Between 2014 and 2015, period compared to the 2013–2014 period for each subgroup. In the
when the tobacco tax increased considerably, quitting smoking was results according to CPD, the 15 + CPD subgroup consistently showed a
induced with the highest frequency. Between 2016 and 2017, when the higher risk ratio of quitting smoking than smokers with less than 15
PCW was introduced, the incidence of quitting smoking was similar to CPD. In particular, the risk ratio of quitting smoking of 15 or more CPD
that of 2015–2016. subgroups during the 2014–2015 period was significantly higher. For
< Supplementary Table 2 > shows the adjusted risk ratio of quit- ITQ, both subgroups also showed the considerably increased risk ratios
ting smoking after the introduction of tobacco control policies reference of quitting smoking in 2014–2015, but no significant difference from
to the previous period of policy introduction for all current smokers. 2013 to 2014 in other periods. < Supplementary Table 4 > shows the
Quitting smoking increased significantly after the increase in tobacco results of the stratified analysis in tabular format.
tax, whereas no significant change occurred after the introduction of In < Supplementary Figure 3 > , we further divided moderate to
PCW. We also analyzed the changes in having 15 or more CPD and heavy smokers into two categories (15–24 CPD and 25 + CPD) and
having an ITQ for smokers who maintained their smoking after the plotted the changes in quitting smoking in these groups. Smoker sub-
introduction of tobacco policies. Smokers with 15 or more CPD de- group of 25 or more CPD showed similar change patterns as the 15–24
creased 0.90 fold (95% confidence interval [CI] (0.86, 0.94)) and with CPD smoker subgroup, although there was a difference in the degree of
no ITQ decreased 0.94 fold (95% CI (0.92, 0.95)) after tobacco tax change. < Supplementary Fig. 4 > shows yearly changes in quitting
increased. However, as in the case of quitting smoking, smokers with 15 smoking according to smokers’ responses to the question about the ITQ.
or more CPD or with no ITQ did not decrease significantly after the Both subgroups of smokers with no ITQ—those who had no plan to quit
introduction of PCW. smoking and those who stated that they planned to do so, but not
Fig. 1 shows the changes in quitting smoking among current smo- within six months—showed similar patterns in terms of quitting
kers according to CPD and ITQ. All subgroups showed a substantial smoking. The subgroups of smokers who responded that they planned
increase in quitting smoking after the tobacco tax was increased in to quit within a month or six months also demonstrated identical pat-
2014–2015. However, only current smokers with 15 or more CPD terns, and they were more likely to quit smoking than other subgroups.
(0.2%p) and an ITQ (2.7%p) showed an increase in quitting smoking We conducted the sensitivity analysis using a sample containing a
after the PCW was introduced compared to the period preceding. five-year follow-up of all participants in 2013. < Supplementary
Table 2 presents the risk ratio of quitting smoking by CPD and ITQ Table 5 > presents the results for quitting smoking among all the par-
for each period. Gradients by CPD and ITQ in quitting smoking con- ticipants who participated in the 2013 survey. Only the point estimates
tinued to be present after adjusting for the explanatory variables. The were slightly different, while the same trends were found as in the re-
difference in quitting smoking between smokers with less than 15 CPD sults of the original analytic sample.
and those with 15 + CPD was relatively small after the tobacco tax was
increased. This result also shows the behavioral affinity of smokers with 4. Discussion
an ITQ for quitting after the introduction of new tobacco control po-
licies. < Supplementary Table 3 > present the results of quitting In this study, we examined differential changes in quitting smoking
smoking for each period, including all explanatory variables. according to CPD and ITQ after the introduction of two tobacco control
Table 3 shows the results of the interaction of each period with CPD policies in Korea: a tobacco tax increase in 2015 and PCW in 2016. The

Fig. 1. Changes in current smokers’ quitting


smoking by daily cigarette consumption and
intention to quit. (A) Changes in quitting
smoking by daily cigarette consumption. (B)
Changes in quitting smoking by intention to
quit.
Notes. CPD = Cigarettes consumed per day;
ITQ = Intention to quit.
Secondhand smoke, gender, age, education,
income, marital status, self-rated health, al-
cohol consumption, and urbanity of residence
were adjusted in the model.
The tobacco tax increase policy was introduced
in January 2015, and the PCW was introduced
in December 2016.

4
I. Kim and Y.-H. Khang Drug and Alcohol Dependence 213 (2020) 108085

Table 2
Main effects model: The risk ratio of quitting smoking for each period according to daily cigarette consumption and intention to quit.
Variables 2013–2014 2014–2015 (Tobacco tax increased) 2015–2016 2016–2017 (PCW introduced)

Adjusted RR (95% CI) P-value Adjusted RR (95% CI) P-value Adjusted RR (95% CI) P-value Adjusted RR (95% CI) P-value

CPD
CPD < 15 Ref. Ref. Ref. Ref. Ref. Ref. Ref. Ref.
15≤CPD 0.42 (0.31,0.56) < .001 0.60 (0.49,0.73) < .001 0.56 (0.43,0.73) < .001 0.58 (0.45,0.76) < .001
ITQ
Having no ITQ Ref. Ref. Ref. Ref. Ref. Ref. Ref. Ref.
Having an ITQ 1.38 (0.87,2.18) 0.171 1.82 (1.40,2.36) < .001 1.43 (1.08,1.89) 0.013 1.79 (1.27,2.54) 0.001

Notes. CI = Confidence interval; CPD = Cigarettes consumed per day; ITQ = Intention to quit; PCW = Pictorial cigarette pack warnings; Ref = Reference; RR =
Risk ratio.
Secondhand smoke, gender, age, education, income, marital status, self-rated health, alcohol consumption, and urbanity of residence were adjusted in the model.
The tobacco tax increase policy was introduced in January 2015, and the PCW was introduced in December 2016.

results of the study showed that the tobacco tax increase by 80% was
more strongly associated with quitting smoking than the PCW (covering
an additional 30% of the front and back of each cigarette pack) in al-
most all subgroups of current smokers categorized by CPD and ITQ. We
also found that smokers with less CPD had a greater likelihood of
quitting smoking. However, when compared to the pre-policy period
(2013–2014) in terms of the relative risk ratio, smokers with 15 + CPD
seemed to be more likely to quit smoking after the tobacco tax increase,
and their tendency to quit smoking remained. ITQ was also positively
related to quitting smoking and seemed to be more responsive to the
introduction of tobacco control policies.
Throughout the entire study period, light smokers stopped smoking
more often, and the same tendency was found for smokers with an ITQ. Fig. 2. Stratified analysis by daily cigarette consumption and intention to quit
These results are in line with the results of numerous previous studies for quitting smoking compared with the 2013-2014 period. (A) Risk ratio for
quitting smoking by daily cigarette consumption. (B) Risk ratio for quitting
(Chaloupka and Warner, 2000; Willemsen, 2005; Ross et al., 2011; Park
smoking by intention to quit.
et al., 2015; Nagelhout et al., 2013; Levy et al., 2004, 2005). The
Notes. CPD = Cigarettes consumed per day; ITQ = Intention to quit.
number of cigarettes smoked in a peak period was found to be nega- Secondhand smoke, gender, age, education, income, marital status, self-rated
tively associated with the likelihood of quitting smoking (Douglas, health, alcohol consumption, and urbanity of residence were adjusted in the
1998). Hammond et al. reported that ITQ was positively related to the model.
cognitive processing of PCW among Canadian smokers, and found that The tobacco tax increase policy was introduced in January 2015, and the PCW
those smokers were more likely to engage in quitting behavior pro- was introduced in December 2016.
spectively (Hammond et al., 2003).
Compared to behavioral trends in 2013–2014, the introduction of smoking.
the tobacco control policy seemed to induce a slightly sharper increase Smokers with an ITQ seemed to be more likely to quit smoking
in quitting smoking in smokers with 15 + CPD than in those with less when the new tobacco control policy was introduced. This may have
than 15 CPD. Previous studies have also reported that smokers with a been because tobacco control policies are particularly helpful for ad-
high CPD were responsive to tobacco control efforts (Hughes, 2011; US dicted smokers with an ITQ (Suranovic et al., 1999). This result may
Department of Health and Human Services, 2003; O’Connor et al., also be linked to the mechanisms inherent in tobacco control policies.
2006). Smokers with high CPD generally quit smoking less frequently For example, PCW is likely to promote quitting behavior in smokers
than smokers with low CPD because they are physically, psychologi- with an ITQ by informing smokers about the detrimental health out-
cally, and socially more dependent on smoking. However, they usually comes of smoking (Noar et al., 2015; Hammond et al., 2013). Analyzing
recognize the detrimental effects of smoking on health and tend to seek using the same subjects in this study, after PCW was introduced, at-
assistance for quitting (Thompson et al., 2003). The introduction of a tempts to quit seemed to increase in smoker subgroups with an ITQ
new tobacco control policy may serve to induce heavy smokers to quit compared to 2013–2014 (adjusted risk ratio: 1.18; 95% CI (0.94,

Table 3
Interactions of time periods with CPD and ITQ as of 2013–2014.
Variables 2014–2015 (Tobacco tax increased) 2015–2016 2016–2017 (PCW introduced)

Adjusted RR (95% CI) P-value Adjusted RR (95% CI) P-value Adjusted RR (95% CI) P-value

CPD
CPD < 15 Ref. Ref. Ref. Ref. Ref. Ref.
15≤CPD 1.40 (0.99,1.98) 0.055 1.29 (0.88,1.90) 0.187 1.37 (0.93,2.02) 0.113
ITQ
Having no ITQ Ref. Ref. Ref. Ref. Ref. Ref.
Having an ITQ 1.29 (0.79,2.12) 0.314 1.01 (0.61,1.68) 0.967 1.29 (0.75,2.21) 0.362

Notes. CI = Confidence interval; CPD = Cigarettes consumed per day; ITQ = Intention to quit; PCW = Pictorial cigarette pack warnings; RR = Risk ratio.
Secondhand smoke, gender, age, education, income, marital status, self-rated health, alcohol consumption, and urbanity of residence were adjusted in the model.
The tobacco tax increase policy was introduced in January 2015, and the PCW was introduced in December 2016.

5
I. Kim and Y.-H. Khang Drug and Alcohol Dependence 213 (2020) 108085

1.49)). An increase in the cigarette tax places an increasing economic 5. Conclusions


burden on heavy smokers, making them more likely to quit smoking
due to the reduction of the marginal utility of each cigarette (Chaloupka This study confirmed that the introduction of tobacco control po-
and Warner, 2000). It is also possible that the effects of the substantial licies in Korea was related to quitting smoking. Light smokers and those
tobacco tax increase on quitting smoking may have been sustained over with an ITQ were more likely to quit smoking. However, compared to
time, and this effect may have impacted the quitting behavior of the the pre-policy period (2013–2014), the quitting smoking of current
remaining smokers. This result suggests that comprehensive im- smokers with 15 + CPD and those with an ITQ seemed to increase after
plementation of the tobacco control policy is required. The introduction the new tobacco control policies were introduced, especially after the
of various policies has a complementary impact on various smoker tobacco tax increase. These results suggest that these tobacco control
subgroups, which can lead to more effective results (Noar et al., 2016; policies acted as a cue-to-action for moderate to heavy smokers and
Levy et al., 2004; Task Force on Community Preventive Services, 2001). smokers who wanted to quit.
The results of this study also provide clues regarding the compara-
tive effects of the two tobacco control policies on quitting behavior. Contributors
Since the increase in tobacco excise tax in 2015 was substantial (an
80% increase), the incidence of quitting smoking was much higher than KIH conceptualized the study. KIH acquired, analyzed, and inter-
for other periods in almost all subgroups. This effect remained present preted data. KIH drafted the original version of the manuscript, and
after the introduction of tobacco excise tax increases. In contrast, when KYH provided critical revisions. All authors have read and approved the
PCW was introduced, a relatively small increase in the incidence of final manuscript.
quitting smoking was observed. This is presumably related to differ-
ences in the type and intensity of these policies, such as the size and Funding
features of warning pictures and phrases (covering 50% of the front and
back of the cigarette pack), compared to the rate of increase (80%) in This research did not receive any specific grant from funding
cigarette prices. Some previous studies showed that a tobacco tax in- agencies in the public, commercial, or not-for-profit sectors.
crease was the most effective policy for lowering the prevalence of
smoking (Levy et al., 2004; Wilson et al., 2012; Levy et al., 2008; Hu Declaration of Competing Interest
et al., 1995). In another previous study, PCW had an independent effect
on smokers’ quitting attempts, but did not have an impact on the suc- The authors have no conflicts of interest to disclose.
cess of those attempts (Borland et al., 2009). However, it may also be
the case that the time order of the two tobacco control policies analyzed Appendix A. Supplementary data
in this study mattered. It is possible that smokers would have responded
more actively to PCW if it had been implemented earlier than the Supplementary material related to this article can be found, in the
substantial tobacco tax increase. online version, at doi:https://doi.org/10.1016/j.drugalcdep.2020.
108085.

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