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Dose Calculations
Dose Calculations
4. How many gray of gamma photons cause the same biological damage as 30 Gy
of alpha radiation with an RBE of 15?
6. A chest x-ray uses 10 keV photons with an RBE of 0.85. A 60-kg person
receives a 0.30 mSv dose from one chest x-ray that exposes 25% of the patient’s
body. How many x-ray photons are absorbed in the patient’s body?
Solution:
1.
E
AD=
m
(
E=( AD ) ( m )= 1.5
J
kg)( 0.150 kg )=0.23 J
2.
E 0.20 J
AD= = =2.0 Gy
m 0.100 kg
3.
Determine the absorbed dose:
E 20 mJ
AD= = =0.4 mGy
m 50 kg
Convert to mrem
(ED )γ =(ED )α
( AD γ )( RBE γ ) =( AD α ) ( RBE α )
AD γ =AD α
( RBE α
RBE γ )
=( 30 Gy )
15
1 ( )
=450Gy
5.
( )
10
−6 3.7 x 10 Bq 6
R=30 x 10 Ci =1.11 x 10 Bq
1 Ci
Determine the decay constant of the beta emitter from its half-life
ln 2 ln 2 −6 −1
λ= = =1.605 x 10 s
t 1 /2
5 days (
24 h 3600 s
1 day 1h )( )
The number of beta particles emitted = the number of nuclei that decayed.
6
R 1.11 x 10 Bq 11
N= = =6.916 x 10
λ 1.605 x 10−6 s−1
Get 90% of the total beta particles emitted. Calculate the total energy.
( )
−13
11 1.6 x 10 J
E=( 25 MeV /beta ) ( 0.90 ) ( 6.916 x 10 ) =0.03485 J
1 MeV
E 0.03485 J −4
AD= = =4.65 x 10 Gy
m 76 kg
Convert to mrem
6.97 x 10
−4
Sv ( 1001 Svrem )( 10001remmrem )=69.7 mrem
6.
−3
ED 0.3 x 10 Sv −4
AD= = =3.53 x 10 Gy∨J /kg
RBE 0.85
( )
−4
10 J
E= 3.53 x ( 0.25 ) (60 kg)=5.29 x 10−3 J
kg
( )=1.6 x 10
−19
1.6 x 10
3 J −15
10 x 10 eV J
1 eV
( )
−3
5.29 x 10 J 12
n= −15
=3.3 x 10 photons
1.6 x 10 J / photon
7.
1 1 1 1 5
t effective= + = + =
t bio t 1/ 2 6 d 9 d 18 d
18 d
t eff = =3.6 days
5