DIVINE WORD COLLEGE OF BANGUED

Bangued, Abra

Department of Nursing
Bachelor of Science in Nursing
Name: Score: Rating: Date:
Course & Year: Instructor’s Signature:

DRUG STUDY
Mechanism of
Generic Name Action Indication Nursing Implications Rationale
Cefazolin Perioperative 1. Before initiating - Persons with a negative
prophylaxis, biliary therapy, obtain a history history of penicillin
tract infections, to determine previous sensitivity may still have
Brand Name Bind to bacterial genital infections, use of and reactions to an allergic response.
Ancef cell wall bacterial penicillins or
membrane, endocarditis, cephalosporins.
Classification prophylaxis for
causing cell death.
Cephalosphorins dental and upper 2. Observe patient for signs - Discontinue medication as
respiratory tract and symptoms of this may indicate an
procedures. anaphylaxis (rash, anaphylactic reaction.
D.R.F.F.T pruritus, laryngeal
Dosage: 1 gram edema, wheezing).
Route: IV - Diarrhea, abdominal
3. Monitor bowel function.
Frequency: Every 8 hours cramping, fever, and
Form: Vial bloody stools should be
Timing: 11:00, 7:00 reported to health care
professional promptly as a
Precautions Contraindications sign of Clostridium
Use cautiously with the following Contraindicated with the
conditions: following conditions:
difficile-associated
Geri: diarrhea (CDAD).
 Does adjustment due to  Hypersensitivity to
age related ↓ in renal cephalosphorins 4. Assess patient for skin - Discontinue
function may be  Serious rash frequently during cephalosporins at first sign
necessary. hypersensitivity to therapy. of rash; may be life-
OB, Lactation: penicillin threatening.
 Half life is shorter and
blood levels lower
during pregnancy
 Have been used safely.

Side Effects Adverse Reactions

GI: CNS:
 Diarrhea  Seizure
 Nausea
 Vomiting GI:
 CDAD
Derm:
 Rashes Derm:
 Steven Johnson
Local: Syndrome
 Pain at IM site
 Phlebitis at IV site Misc:
 Anaphylaxis
 Serum sickness
DIVINE WORD COLLEGE OF BANGUED
Bangued, Abra

Department of Nursing
Bachelor of Science in Nursing