Professional Documents
Culture Documents
Triumph Over Alzheimer
Triumph Over Alzheimer
Alzheimer
1
"David Olson has provided a comprehensive
and compassionate overview of the illness,
offering insight and practical advice on how to
cope with the day-to-day challenges. The
author's research is thorough and the writing
style is engaging and easy to understand. The
book is full of encouragement and hope, an
essential resource for anyone affected by
Alzheimer’s, this book is a powerful reminder
that this is not the end."
2
Triumph
Over
Alzheimer
A Compendium with Cognitive
Strategies to Find Hope and
Strength and Reduce Your Risk of
Alzheimer's disease
David Olson
3
Text Copyright © 2023 David
Olson
All rights reserved. No part of this book may
be reproduced in any form or by any
electronic or mechanical means, including
information storage and retrieval systems,
without written permission from the
author, except for the use of brief
quotations in a book review. This book is
intended to provide helpful and informative
material on the topic of managing
Alzheimer’s disease. The information
contained herein is not intended to replace
the advice of a qualified healthcare
professional. All readers are advised to seek
professional medical advice when
necessary. The author and publisher shall
not be liable for any damages resulting from
the use of the information contained
herein.
First edition, 2023
4
Contents
Praise for Triumph over Alzheimer
Copyright
PART I
Introduction to Alzheimer Disease and
Its Impact
5
PART II
Etiology of Alzheimer's Disease
1. Cardiovascular disease
2. Age: A Huge Factor
3. Genetics
4. Diabetes
5. Down syndrome
6. High Blood Pressure
7. Environmental Toxins
8. Vitamin Deficiencies
9. Obesity
10. Social Isolation/ Depression
6
Part III
A Comprehensive Overview of Remedies
and Therapies
1. Medications
2. Cognitive-Behavioral Therapy
3. Physical Exercise
4. Non-Drug Remedies
5. Nutritional and Dietary Therapies
6. Aromatherapy and Acupuncture
7. Light, Massage and Virtual reality
Therapy
8. Non-Pharmacological Interventions
7
PART I
Introduction to Alzheimer
Disease and Its Impact
8
CHAPTER 1
Alzheimer’s disease (Ad)
Alzheimer's disease is a progressive
neurodegenerative disorder that
gradually affects a cognitive function,
including memory, thinking, behavior,
and ability to perform everyday
activities.
9
The cause of Alzheimer's is not
completely understood, but is thought
to involve the buildup of proteins in the
brain that form plaques and tangles,
which interfere with communication
between neurons. This damage affects
different parts of the brain, leading to
the different symptoms of the disease.
Common early symptoms of
Alzheimer's include difficulty
remembering recent events, trouble
performing familiar tasks, confusion
with time and place, and changes in
personality. As the disease progresses,
symptoms become more severe,
including difficulty speaking and
understanding, confusion and
disorientation, increased difficulty with
activities of daily living, and eventually
complete dependence on caregivers.
10
There is no known cure for Alzheimer
disease, but remedies are available to
help manage symptoms and slow the
progression of the disease.
11
atrophy of the brain tissue. As the
disease progresses, it can cause
problems with basic activities of daily
living such as eating, bathing, and
dressing.
13
CHAPTER 2
Cognitive Decline Symptoms
1. Memory loss: One of the hallmark
signs of Alzheimer’s is memory loss,
particularly of recent events and
conversations. This can include things
such as forgetting recently learned
information, important dates or events,
and more.
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8. Poor judgment or reduced
inhibition: People with Alzheimer’s
may have difficulty making decisions or
understanding the consequences of
their actions.
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CHAPTER 3
Impact of Alzheimer Disease
on Families
My grandma was a woman who had
always lived life to the fullest. She was
a loving wife, mother, and
grandmother who enjoyed spending
time with her family, gardening,
cooking, and traveling. Unfortunately,
at the age of 70, my grandma was
diagnosed with Alzheimer’s disease.
Although it was difficult to accept, my
grandma and our family decided to
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face the challenges of the disease
together.
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time to care for yourself and find
moments of joy and peace. While
Alzheimer's can be a devastating
disease, families can still find love and
meaning in their relationships with
their loved one. Cherish the moments
you have together.
22
Overall, Alzheimer's disease can have a
major impact on the family of the
person diagnosed with it. It is
important for family members to find
ways to bring happiness and comfort to
your loved one, and reach out for help
when you need it.
PART II
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Etiology of
Alzheimer’s disease
CHAPTER 4
Cardiovascular Disease
Cardiovascular disease is a major risk
factor for Alzheimer’s disease. The two
diseases are closely linked, as the
healthy functioning of the
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cardiovascular system is essential for
maintaining overall brain health.
Studies have shown that cardiovascular
disease can lead to a reduction in blood
flow to the brain, which can result in a
decrease in the levels of oxygen and
nutrients that the brain needs to
function properly. This can lead to
physical damage to the brain, including
the accumulation of proteins
associated with Alzheimer's disease.
Additionally, cardiovascular disease can
also lead to a buildup of plaque in the
brain, which can further contribute to
cognitive decline.
26
Another way that cardiovascular
disease can contribute to the
development of Alzheimer's disease is
through the buildup of amyloid
proteins in the brain.
27
can further contribute to the
development of Alzheimer's disease.
CHAPTER 5
Age: A Huge factor
Age is one of the most significant risk
factors for Alzheimer’s disease. As
people age, their risk increases
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substantially; the majority of people
with Alzheimer’s are 65 years of age or
older. While the reason for this
increased risk is not yet known,
scientists theorize that the
accumulation of age-related damage to
the brain may play a role. It is also
possible that the aging process itself
may lead to changes in the brain that
makes it more vulnerable to the
development of Alzheimer’s.
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CHAPTER 6
Genetics
Genetics is believed to be a risk factor
in the development of Alzheimer’s
disease. While the exact mechanism is
not yet known, researchers have
identified several genes that may be
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involved in the development of the
disease. For example, mutations in the
genes APP, PSEN1, and PSEN2 have
been associated with an increased risk
of developing the disease. Additionally,
certain variations in the APOE gene
may be associated with an increased
risk of developing the disease.
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While genetics may play a role in the
development of Alzheimer’s, it is
important to note that the disease is
not caused by any single gene. Rather,
it is likely the result of a combination of
genetic and environmental factors.
Several genes have been identified as
being associated with an increased risk
of developing Alzheimer’s disease or as
risk factors for the disease. These
include:
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• Apolipoprotein E (APOE) – is a gene
that produces a protein involved in the
transport of cholesterol and other
lipids in the brain. Certain variations in
this gene have been associated with an
increased risk of developing
Alzheimer’s disease, though the exact
mechanism is not yet known. It is
thought that these variations may lead
to an altered transport of lipids in the
brain, which could contribute to the
development of the disease.
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This gene is involved in the transport of
proteins across the outer membrane of
mitochondria and has been linked to
the development of Alzheimer's by
affecting the processing of amyloid
precursor protein (APP), which is
involved in the formation of amyloid
plaques, a hallmark of Alzheimer's
disease. By disrupting the normal
processing of APP, TOMM40 may lead
to the accumulation of amyloid plaques
and contribute to the development of
Alzheimer's disease.
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CHAPTER 7
Diabetes
Diabetes is a chronic condition that
occurs when a person’s body is unable
to properly regulate its blood sugar
levels. Diabetes is a condition marked
by elevated blood sugar levels, which if
not addressed can lead to serious
health issues. Typical signs of diabetes
41
include increased thirst, having to go to
the bathroom frequently, extreme
hunger, fatigue, and blurred vision.
Diabetes can be managed through
lifestyle changes such as maintaining a
healthy diet, exercising regularly, and
monitoring blood sugar levels. In some
cases, medication may also be
prescribed to help manage blood sugar
levels.
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CHAPTER 8
Down syndrome
Down syndrome is a genetic disorder
caused by the presence of an extra
chromosome 21 in a person’s cells,
resulting in a range of physical and
cognitive disabilities.
People with Down syndrome have an
increased risk of developing a number
44
of medical conditions, including
Alzheimer’s disease. This increased risk
is thought to be due to a number of
factors, including a higher prevalence
of certain genetic variants associated
with Alzheimer’s, as well as premature
aging and an impaired ability of the
body to clear out amyloid plaques,
which are a hallmark of the disease.
In addition, people with Down
syndrome often have a higher risk of
developing conditions that can lead to
Alzheimer’s, such as stroke, head
trauma, and vascular disease. While the
risk of developing Alzheimer’s is higher
for people with Down syndrome,
research suggests that the progression
of the disease may be slower, meaning
that those affected may experience a
longer period of mild to moderate
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cognitive decline before more severe
symptoms set in.
CHAPTER 9
High Blood Pressure
High blood pressure, also known as
hypertension, is a chronic medical
condition characterized by abnormally
high levels of blood pressure in the
arteries. It is a major risk factor for a
number of medical conditions,
including stroke, heart attack, and
dementia. Research suggests that high
46
blood pressure may also increase the
risk of developing Alzheimer’s disease.
This is thought to be due to the fact
that high blood pressure can lead to
damage of the small blood vessels in
the brain, which can reduce the
amount of oxygen and nutrients that
can be delivered to the brain. This can
lead to damage of the nerve cells in the
brain, which can contribute to the
development of Alzheimer’s disease. In
addition, high blood pressure can
increase the risk of stroke, which can
also increase the risk of Alzheimer’s.
CHAPTER 10
Environmental Toxins
Environmental toxins are substances
found in the environment that can be
harmful to human health. These toxins
can come from a variety of sources,
such as industrial waste, air pollution,
and contaminated food and water.
Exposure to environmental toxins has
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been linked to an increased risk of
developing Alzheimer’s disease.
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CHAPTER 11
Vitamin Deficiencies
Vitamin deficiencies are a common
nutritional issue that can have a
number of serious health effects.
Research suggests that certain vitamin
deficiencies may be associated with an
increased risk of developing
51
Alzheimer’s disease. This is thought to
be due to the fact that certain vitamins,
such as vitamin B12, are involved in the
regulation of certain metabolic
processes in the body, and a deficiency
of these vitamins can impair the body’s
ability to clear out amyloid plaques,
which are a hallmark of the disease. In
addition, certain vitamins, such as
vitamin D, are involved in the
regulation of inflammation, which is
thought to be involved in the
development of Alzheimer’s.
CHAPTER 12
Obesity
Obesity is a long-term health condition
characterized by an excessive amount
of fat stored in the body. Research
suggests that obesity may be
associated with an increased
53
Risk of developing Alzheimer’s disease.
This is thought to be due to the fact
that obesity can lead to an impaired
ability of the body to clear out amyloid
plaques, which are a hallmark of the
disease, as well as an increased risk of
developing conditions that can lead to
Alzheimer’s, such as stroke and
vascular disease. In addition, obesity
can also lead to inflammation and
oxidative stress, both of which are
associated with an increased risk of
Alzheimer’s.
The effects of obesity on human health
can be far-reaching and serious. In
addition to increasing the risk of
developing Alzheimer’s, obesity can
also lead to other
Health problems, such as diabetes,
heart disease, and certain types of
54
cancer. It is therefore important to take
steps to reduce the risk of obesity, such
as maintaining a healthy diet,
exercising regularly, and limiting the
intake of processed and sugary foods. It
is also important to ensure that any
weight loss is done in a healthy and
sustainable way, as rapid weight loss
can lead to other health problems.
CHAPTER 13
Social Isolation/Depression
Social isolation and depression are two
common mental health issues that can
have a negative impact on overall
health. Research suggests that social
isolation and depression may be
associated with an increased risk of
55
developing Alzheimer’s disease. This is
thought to be due to the fact that
social isolation and depression can lead
to an impaired ability of the body to
clear out amyloid plaques, which are a
hallmark of the disease, as well as an
increased risk of developing conditions
that can lead to Alzheimer’s, such as
stroke and vascular disease. In
addition, social isolation and
depression can also lead to
inflammation and oxidative stress, both
of which are associated with an
increased risk of Alzheimer’s.
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types of cancer. It is therefore
important to take steps to reduce the
risk of social isolation and depression,
such as maintaining social connections,
engaging in activities that bring joy, and
seeking help from a mental health
professional when needed. It is also
important to ensure that any remedy
for social isolation and depression is
done in a healthy and sustainable way,
as rapid improvements can lead to
other health problems.
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PART III
58
A Comprehensive
Overview of Remedies
and Therapies
CHAPTER 14
Medications
1. Cholinesterase inhibitors: These
medications help to increase the levels
of certain neurotransmitters in the
brain, which can improve memory,
thinking, and behavior. Examples
59
include donepezil (Aricept),
galantamine (Raza dyne), and
rivastigmine (Exelon).
60
Examples include citalopram (Celexa)
and sertraline (Zoloft).
5. Acetylcholinesterase inhibitors:
These medications are used to manage
mild to moderate Alzheimer’s.
Examples include tacrine (Cognex) and
donepezil (Aricept).
CHAPTER 15
Cognitive-Behavioral
Therapy
Cognitive Behavioral Therapy (CBT) is a
form of psychotherapy that is designed
61
to help individuals identify and adjust
negative thoughts and behaviors. This
approach focuses on the idea that our
thoughts, feelings, and behaviors are all
connected, and that changing one can
help to change the others. CBT is used
to manage a wide range of mental
health issues, including depression,
anxiety, and PTSD. The goal of CBT is to
help people develop skills to manage
their thoughts, feelings, and behaviors
in more positive ways. This can lead to
improved mental health, better
relationships, and more satisfying lives.
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CHAPTER 16
Physical Exercise
1. Walking: Walking is a great form of
exercise for individuals with
Alzheimer's disease. It's low-impact and
can be done indoors or outdoors. Start
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off slowly with 10–15-minute walks,
and gradually increase the length and
intensity of the walks.
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and can help to improve balance and
coordination.
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aerobic workout, as well as helping to
improve balance and coordination.
CHAPTER 17
Non-Drug Remedies
1. Cognitive Stimulation: Cognitive
stimulation involves activities that help
to improve memory and thinking skills
in individuals with Alzheimer's. These
activities can include word games,
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puzzles, and memory exercises. The
goal of cognitive stimulation is to help
individuals to maintain their mental
abilities, as well as to delay the onset of
symptoms of Alzheimer's.
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3. Nutritional Supplements: Certain
nutritional supplements have been
found to be beneficial for individuals
with Alzheimer's. These include omega-
3 fatty acids, vitamin E, B vitamins, and
ginkgo biloba. The goal of taking
nutritional supplements is to help
improve cognitive function, as well as
to reduce the risk of developing
Alzheimer's.
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CHAPTER 18
Nutritional and Dietary
Therapies
1. Adequate Nutrition: Ensuring that
individuals with Alzheimer's are getting
71
the right balance of nutrients, vitamins,
and minerals is essential. Eating a
balanced, nutrient-dense diet can help
to reduce the risk of developing
Alzheimer's and can also help to slow
the progression of the disease.
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CHAPTER 19
Aromatherapy and
Acupuncture
Aromatherapy is a type of holistic
healing that involves the use of
essential oils from plants to promote
wellbeing. Essential oils are extracted
74
from plants and contain unique
compounds that can have a variety of
therapeutic effects. Aromatherapy is
believed to have several benefits,
including improving mood, reducing
stress, and improving cognitive
function.
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The effects of aromatherapy vary
depending on the individual, the
essential oil used, and how it is used. In
general, aromatherapy is believed to
have a calming effect, as well as to help
reduce stress, anxiety, and depression.
Additionally, it has been found to have
some cognitive benefits, such as
improving memory and concentration.
Finally, aromatherapy may also help to
improve sleep and boost the immune
system.
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2. Peppermint: Peppermint has been
found to have a calming effect on
individuals with Alzheimer's. It can help
to reduce agitation and improve
cognition.
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5. Bergamot: Bergamot has been found
to help improve cognition in individuals
with Alzheimer's. It also helps to reduce
stress and improve mood.
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to the body’s natural energy (qi) and
promote healing. Acupuncture has
been found to be beneficial for a
variety of conditions, including chronic
pain, migraines, anxiety, and
depression. It can also be used to help
improve sleep, reduce stress, and boost
the immune system.
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different techniques, such as heat or
electrical stimulation, to further
enhance the effects.
82
5. Abdominal Acupuncture: Abdominal
acupuncture is used to manage a
variety of conditions, including
Alzheimer's. It involves the insertion of
thin needles into specific points on the
abdomen, which can help to improve
cognition and reduce agitation.
CHAPTER 20
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Light, Massage and Virtual
Reality Therapy
Light therapy, also known as
phototherapy, is a form of remedy that
uses natural or artificial light to
improve physical and mental health. It
is based on the idea that exposure to
light can have a positive effect on mood
and behavior. Light therapy typically
involves sitting in front of a light box for
a prescribed amount of time each day.
The light box emits a bright, white light
that is much brighter than normal
indoor lighting.
84
type of depression that occurs in the
winter months when days are shorter
and sunlight is limited. Research has
shown that light therapy can help
reduce the symptoms of SAD, such as
fatigue, difficulty concentrating, and
low mood.
85
Light therapy works by resetting the
body's internal clock, or circadian
rhythm. Exposure to bright light during
the day helps to regulate the body's
natural rhythm, which can lead to
improved sleep, energy levels, and
mood.
86
It is important to follow the
instructions of a healthcare provider
when performing light therapy.
88
specialized training in anatomy,
physiology, and massage techniques.
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levels of oxytocin, a hormone
associated with feelings of relaxation.
CHAPTER 21
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Non-Pharmacological
Interventions
Reality Orientation: Reality
orientation is a therapeutic technique
used to help people with dementia and
other cognitive impairments stay
oriented to their current surroundings.
It involves providing patients with
frequent reminders of time, date,
place, and other relevant information
as well as orienting them to the
environment. It is usually done in a
repetitive and structured manner and
can be used to help reduce confusion
and disorientation. Reality orientation
can also be used to help improve
communication and interactions
between caregiver and patient. Reality
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orientation can help those with
Alzheimer's by providing them with a
sense of familiarity and security. By
providing frequent reminders of time,
date, place, etc., it can help reduce
confusion and disorientation and
improve communication and
interactions. Additionally, it can help
reduce stress and anxiety levels by
providing a sense of structure and
routine. Finally, reality orientation can
help improve quality of life by helping
those with Alzheimer's feel more
connected to their current
environment and less isolated.
Reminiscence Therapy:
Reminiscence therapy is a therapeutic
technique used to help people with
95
dementia and other cognitive
impairments recall past memories. It
involves providing patients with
prompts and activities to help them
access and reflect on past experiences
and memories. It can be used to help
improve communication and social
interaction as well as reduce anxiety
and depression. Additionally, it can
help improve quality of life by providing
a sense of comfort and familiarity.
96
reflect on past experiences and
memories. Additionally, it can help
improve overall quality of life by
providing a sense of connection and
purpose.
103
Living with
Alzheimer’s Disease
Living with Alzheimer's is no small feat.
It is a difficult journey and can be very
overwhelming for those affected and
for their families. Fortunately, there are
many resources available to help those
living with Alzheimer's and their
families manage the disease. These
include support groups, counseling,
and medication to help reduce
symptoms. For those living with
Alzheimer's and their families, know
that you are not alone. Although this
journey may be difficult, there is always
hope. There are resources available to
help manage the disease and there are
people who care and want to help. You
are not alone in this fight. It is
104
important to take care of yourself and
practice self-care. Focus on things that
bring joy and make life meaningful.
Reach out to your support system and
connect with others who understand
what you are going through. By having
access to resources, practicing self-
care, and connecting with others, living
with Alzheimer's can be manageable.
With proper care and support, those
affected can continue to lead fulfilling
lives, remember that recovery is
possible. With dedication and
perseverance, you can continue to
achieve your goals and live a
meaningful life. You are strong and you
can get through this.
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