List of Reducing Agents Chemistry CAG

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NaBH4 +
B2H6 in
Product on LiAlH4 in NaBH4 in AlCl3 in H2/( Metal
S.No. THF
Group reduction Ether EtOH diglyme Catalyst)

1. CHO CH2OH + + + + +

2. C  O CHOH + + + + +

3. COOH CH2OH + - + + - *
4. COO CH2OH + - + - -

5. COCl CH2OH + + + - +

RCH2OH
6.
RCOOR '
 R'OH + - + +

7. RCO2 O RCH2OH + - + + +

8. Epoxide Alcohol + - + + +

9. Lactone Diol + - + + +

10. CONH2 CH2NH2 + - + + +

11. CN CH2NH2 + - + + +

12. C  N  OH CH2NH2 + +

ArN  NAr
13.
ArNO2 (alsoin A mines) + - - - +

14. RNO2 RNH2 + - - - +

15. C  C CH  CH - - + + +

16. C  C  CH2  CH2  - - + +

17. RX RH + + - - +

18. ArX ArH - - +

* H2 / Ni at elevated temperature and high pressure Reduces the acids into Alkanes.
RCOOH + 3H2 / Ni  RCH3 + 2H2O
However, By taking [Ru-C] catalyst or [Cu-Ba-Cr oxide] catalyst, acid can be converted to Alcohol

Note: 1. Diglyme: CH3OCH2CH2OCH2CH2OCH3 (solvent)

2. Lactone: Cyclic ester

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 List of Reducing Agents Chemistry CAG
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Ease of Reduction of various functional groups by

LiAlH4 in ether
S. No. Substrate Product Ease of Reduction

1. CHO CH2OH Easiest

2. C  O CHOH

3. COCl CH2OH

4. Lactone Diol

5. Epoxide Alcohol

6. RCH2OH
RCOOR '
 R'OH

7. COOH CH2OH

8. COO CH2OH

9. CONR2 CH2NR2

10. CN CH2NH2

11. RNO2 RNH2

12. ArNO2 ArN  NAr Most Difficult

13. C  C CH  CH Inert

Source: 1. I L FINAR
2. Jerry March

FIITJEE CAG