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MANALO SAMPANG Module 1 Assignment Framework Genetics
MANALO SAMPANG Module 1 Assignment Framework Genetics
Sampang, Chayna
NU-204
3. The parents brought their 3-year-old child to the health center due to cough,
colds, and fever for 3 days. Upon examination, the nurse noticed the
following characteristics: poor muscle tone, protruding tongue, slanted
palpebral fissure, wide space between the first and second toes, simian line.
The mother is already 48 years old while the father is 55 years old.
- The child described in the situation displays physical traits indicative of Down
syndrome or Trisomy 21. The observed features, such as diminished muscle
tone, tongue protrusion, slanted palpebral fissure, wide gap between the first
and second toes, and the presence of a simian line, align with the typical
manifestations of Down syndrome. It is plausible that the child's karyotype
would reveal a chromosomal arrangement of 47XY21+ or 47XX21+, indicating
the presence of an additional chromosome 21. The physical attributes noted
correspond with the well-known signs of Down syndrome, and the ages of the
parents 48 years for the mother and 55 years for the father are in line with the
heightened risk of chromosomal abnormalities, particularly trisomy 21.
Maternal age beyond 35 is recognized as a significant factor contributing to
chromosomal anomalies, with Down syndrome being more prevalent in older
mothers.