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Madison Kretzler, Jesse Hamilton, Mark Griswold, and Nicole Seiberlich 1 2 2,3 2,3
Madison Kretzler, Jesse Hamilton, Mark Griswold, and Nicole Seiberlich 1 2 2,3 2,3
Madison Kretzler1 , Jesse Hamilton 2 , Mark Griswold 2,3 , and Nicole Seiberlich 2,3
1 Electrical Engineering, Case Western Reserve University, Cleveland, OH, United States, 2 Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, 3 Radiology, University
Hospitals, Cleveland, OH, United States
Synopsis
This abstract presents af BLAST, a noniterative approach to nonCartesian kt BLAST for radial trajectories, and demonstrates its use for
accelerated cardiac imaging.
Purpose
kt BLAST 1 is a technique that works in the spatiotemporal frequency domain (xf space) to resolve aliasing caused by lattice undersampling of the kt
space. Due to the strategic kt sampling pattern, aliasing patterns in the in the xf space are predictable and can be resolved using additional
information from a training dataset. Previous methods for extending the concepts of kt BLAST to nonCartesian trajectories focused on solving the
general inversion problem using an iterative conjugate gradient (CG) method2, but this approach can be timeconsuming and does not take advantage
of the symmetry inherent in some commonlyused trajectories. This method presents a noniterative extension of Cartesian kt BLAST to dynamic
radial imaging by using the radial symmetry of the data to simplify the reconstruction problem.
Methods
In Cartesian kt BLAST the kspace is undersampled in an interleaved fashion, which produces an offset aliasing pattern in the xf space. Unlike
Cartesian data, radially sampled data does not produce an aliased image with the clear aliasing artifacts required for kt BLAST. However, the Radon
transform of the underlying image can be generated by performing a Fourier transform only along the readout direction; a subsequent Fourier
transform along the projection direction will result in aliasing artifacts that are similar to those seen in Cartesian kt BLAST. We refer to this domain as
the “aliased space,” as shown in Figure 1. This space can then be Fourier transformed through time to obtain a type of xf space, which we call the af
space, where the necessary offset aliasing is present to perform the kt BLAST reconstruction. Lowresolution training data can be obtained from the
center of kspace of the undersampled radial data. After the kt BLAST reconstruction in af space, the reconstructed data are transformed back into
radial kspace, and then gridded using the NUFFT 3. This technique was first applied to invivo cardiac breathheld cine scans downsampled to mimic
different acceleration factors. These data were collected along an interleaved radial trajectory on a Siemens Skyra 3T wholebody scanner with a
bSSFP sequence using TR = 29 ms, TE = 1.5ms, BW = 1 kHz, FoV = 300mm, spatial resolution = 2.3x2.3x8.0 mm3, flipangle = 57 degrees. Matrix
dimensions were 128x128 with 144 fully sampled projections for the cine and 144/R for the accelerated scans. The fullysampled cine images were
used to calculate RMSE values for the reconstructed image series. Additionally, af BLAST was applied to prospectively accelerated realtime radial
scans with R=4 and the same scan parameters as the cine dataset with the following exceptions: TR=2.94ms, flip angle=37 degrees.
Results
Figure 2 shows that af BLAST reduces the radial artifacts from a retrospectively undersampled cine dataset with R=4 without compromising the
temporal resolution in the xt images. Figure 3 shows the RMSE values for reconstructions of varying acceleration factors. It can be seen for
increasing accelerations RMSE values steadily increase and image quality deteriorates. Figure 4 shows the performance of af BLAST for
prospectively accelerated R=4 radial data. Figure 5 is a gif showing the same dataset as Figure 4 in an animated form.
Discussion/Conclusion
af BLAST, or noniterative nonCartesian kt BLAST performed in Radon space, may enable a significantly faster reconstruction of radially
undersampled images by removing the gridding/degridding steps required in nonCartesian kt BLAST.2 The af BLAST approach does not require a
separate training dataset, as the center of kspace can be used as the lowresolution training data. However, the two techniques have not been
compared for speed or performance, which depends on the relative sparsity of the data in each of the domains (af vs. xf). af BLAST also presents a
new space which can be used to rapidly reconstruct undersampled radial data, which may be advantageous for other reconstruction techniques,
including nonCartesian parallel imaging and compressed sensing.
Acknowledgements
No acknowledgement found.
References
1. Tsao, J., Boesiger, P. & Pruessmann, K. P. kt BLAST and kt SENSE: Dynamic MRI With High Frame Rate Exploiting Spatiotemporal Correlations.
Magn. Reson. Med. 50, 1031–1042 (2003).
2. Hansen, M. S. et al. kt BLAST reconstruction from nonCartesian kt space sampling. Magn. Reson. Med. 55, 85–91 (2006).
3. Fessler, J. A. & Sutton, B. P. Nonuniform fast fourier transforms using minmax interpolation. IEEE Trans. Signal Process. 51, 560–574 (2003).
Figures
Figure 1: Undersampled interleaved radial data (far left) can be transformed into a space that has an appearance similar to undersampled Cartesian data in xf space (far right) by performing Fourier
transforms along each dimension without gridding. The aliasing in this af space can be resolved with a kt BLAST reconstruction, followed by gridding of the radial data to generate an image.
Figure 2: An example of af BLAST, showing (top) the fullysampled invivo cardiac cine, R=4 Nyquistsampled, R=4 zerofilled, and R=4 reconstructed images, and xt images of single heartbeat for each
(bottom).
Figure 3: af BLAST reconstructions of the same retrospectively undersampled radial cine data as Figure 2 and their RMSE values with varying acceleration factors.
Figure 4: af BLAST performed on prospectively accelerated cardiac images with a temporal resolution of 105.84ms and R = 4 for frames in diastole (top), systole (center), and the xt space (bottom).
Figure 5: Gif of the R=4 af BLAST reconstructions from Figure 4 showing zerofilled, Nyquistsampled, and af BLAST images (from left to right).