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LifeScience

Citylight Complex

NEET CELL CYCLE AND CELL DIVISION


NEET-UG - Biology
Time Allowed: 45 minutes Maximum Marks: 300

1. What will be the DNA content of the cells at G1, after S and at G2 respectively, if the content after M-phase is [4]

2C in cells of the root tip of onion?

a) 2C, 4C, 4C b) C, 2C, 2C

c) 2C, 2C, 2C d) C, 4C, 2C


2. In the pachytene, each bivalent chromosome contains _________ chromatids. [4]

a) Two b) Eight

c) Four d) Many
3. Period of active mitosis ranges from: [4]

a) One day to a week b) 10 minutes to few hours

c) A few hours to one day d) Less than 1 minute


4. Microtubule depolymerising during such as colchicine is expected to [4]

a) Induce forman of multiple contractile rings b) Allow mitosis beyond metaphase

c) Inhibit cytokinesis d) Inhibit mitosis but allow cytokinesis


5. Morphology of chromosomes is most easily studied in: [4]

a) Prophase b) Anaphase

c) Metaphase d) Telophase
6. Number of meiotic divisions required to produce 100 macrospores in angiosperm/egg is: [4]

a) 25 b) 100

c) 125 d) 50
7. Centromere is required for: [4]

a) Chromosome segregation b) Replications of DNA

c) Pole ward movement of chromosomes d) Cytoplasmic cleavage


8. Which is called direct cell division? [4]

a) All cell divisions b) Meiosis

c) Mitosis d) Amitosis
9. Nuclear membrane disappears at: [4]

a) Anaphase b) Late prophase

c) Early prophase d) Metaphase

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10. During which of the following meiosis occur? [4]

a) Megasporogenesis b) Gametogenesis

c) All of these d) Microsporgenesis


11. In syncytium: [4]

a) Karyokinesis not occurs b) Both Karyokinesis and Cytokinesis occurs

c) Both Karyokinesis not occurs and d) Cytokinesis not occurs


Cytokinesis occurs
12. In S phase of the cell cycle: [4]

a) Amount of DNA remains same in each cell b) Chromosome number is increased

c) Amount of DNA is reduced to half in each d) Amount of DNA doubles in each cell
cell
13. During which phase(s) of cell cycle, the amount of DNA in a cell remains at 4 C level if the 7. initial amount is [4]
denoted as 2C?

a) G0 and G1 b) Only G2

c) G2 and M d) G1 and S

14. During which stage of spermatogenesis the chromosomes are associated with tetrads? [4]

a) Leptotene b) Diplotene

c) Pachytene d) Zygotene
15. Chromosome start separating at which stage of mitosis? [4]

a) Early metaphase b) Late metaphase

c) Early anaphase d) Late telophase


16. Meiosis occurs in tomato in: [4]

a) Pollen sac and ovule b) Pollen sac and ovule and Microspore
mother cell

c) Microspore mother cell d) Zygote


17. In which sub-phase of interphase, damaged DNA is repaired? [4]

a) G1 b) M-phase

c) S - phase d) G2

18. The given images illustrate a sequence in cell division: [4]

The missing stage X in the above sequence is:

a) b)

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c) d)

19. Which of the following phases corresponds to the interval between mitosis and initiation of DNA replication? [4]

a) G2 - phase b) G1 - phase

c) S - phase d) Cytokinesis
20. How many statements are correct for the growth of organisms? [4]
i. All organisms, even the largest, start their life from a single cell.
ii. Growth and reproduction are characteristics of cells.
iii. Cycles of growth and division allow a single cell to form a structure consisting of millions of cells.
iv. Cell division is a very important process in only higher living organisms.
v. During the division of a cell, DNA replication and cytoplasmic increase also take place.
vi. The sequence of events in which cell division, DNA replication and cell growth take place, is called cell
cycle.

a) Four b) Six

c) Five d) Three
21. In Spirogyra / Ulothrix / Chlamydomonas / Thallophytes meiosis occurs in: [4]

a) Zygospore / zygote germination b) Gametangium

c) Egg formation d) Oosphere formation


22. The type of meiosis occurring before fertilization is called: [4]

a) Sporic b) Azygotic

c) Gametic d) Zygotic
23. Centromeres split and chromatids separate in: [4]

a) Starting of anaphase b) Starting of metaphase

c) End of anaphase d) End of metaphase


24. RNA and protein synthesis occurs in: [4]

a) G1 - phase b) S - phase

c) G2 - phase d) Both G1 - phase and G2 - phase

25. A stage in cell division is shown in the figure. Select the answer which gives correct identification of the stage [4]
with its characteristics.

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a) Telophase - E. R. and nucleous not formed b) Cytokinesis - Cell plate formed,
yet mitochondria distributed between two
daughter cells

c) Telophase - Nuclear envelop reforms, Golgi d) Late anaphase - Chromosomes move away
complex reforms from equatorial plate, Golgi complex not
present
26. Some dividing cells exit the cell cycle and enter the vegetative inactive stage. This is called the quiescent stage [4]
(G0). This process occurs at the end of:

a) M phase b) G1 phase

c) S phase d) G2 phase

27. In the 24 hours average duration of cell cycle of a human cell, cell division proper lasts for only about: [4]

a) 5 hours b) 19 hours

c) 1 hour d) 10 hours
28. All organisms, even the largest, start their life from a single cell, how a single cell goes on to form such large [4]
organisms:

a) By growth only b) By cycles of growth and division or


reproduction

c) By cell elongation only d) By reproduction only


29. The enzyme recombinase is required at which stage of meiosis: [4]

a) Diplotene b) Pachytene

c) Diakinesis d) Zygotene
30. The centriole, which had undergone duplication during S-phase of interphase, begins to move towards opposite [4]
poles of the cell in which phase?

a) Metaphase b) Anaphase

c) Prophase d) Telophase
31. Certain stages of cell division are represented by given figures. Identify them correctly: [4]

a) A - Metaphase - II, B - Transition to b) A - Metaphase I, 3 - Transition to

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metaphase, C - Anaphase - II metaphase, C - Anaphase - I

c) A - Metaphase - I, B - Prophase - I, C - d) A - Metaphase, B - Anaphase, C -


Anaphase - I Telophase
32. In cell cycle, DNA doubles in its amount due to its synthesis (replication or duplication). It occurs in: [4]

a) I - phase b) G1 - phase/Post mitotic phase

c) G2 -phase/Pre mitotic phase d) Synthetic (S) - phase

33. What happens in meiosis? [4]

a) One division of nucleus and one division of b) Two divisions of nucleus and two divisions
chromosomes of chromosomes

c) Two divisions of nucleus and one division d) One division of nucleus and two divisions
of chromosomes of chromosomes
34. In which of the following stages chromosomes are fully condensed and the meiotic spindle is assembled to [4]
prepare the homologous chromosomes for separation and at their end, the nucleolus disappears and the nuclear
envelope also breaks down?

a) Diakinesis b) Zygotene

c) Leptotene d) Pachytene
35. Which is of shortest duration in the cell cycle? [4]

a) S b) G1

c) M d) G2

36. At which stage of meiosis does the genetic constitution of gametes is finally decided? [4]

a) Anaphase - II b) Anaphase - I

c) Metaphase - I d) Metaphase - II
37. Which of the following statements are true? [4]
i. Some cells in the adult animals do not appear to exhibit division.
ii. Many cells of animals divide only occasionally.
iii. These cells that do not divide further exit G1 - phase to enter an inactive stage called G0.
iv. Cells in quiescent stage remain metabolically active but no longer proliferate unless called on to do so.
v. In animals, mitotic cell division is only seen in the haploid somatic cells.
vi. Plants can show mitotic divisions in both haploid and diploid cells.

a) (i), (ii), (iv) and (v) b) (i), (ii), (iii), (v) and (vi)

c) (i), (ii) and (iii) d) All except (v)


38. Which of the following is true for G1-phase? [4]

a) DNA synthesis or replication takes place b) Amount of DNA per cell doubles

c) Amount of chromosome per cell doubles d) Cell is metabolically active and


continuously grows but does not replicate
its DNA

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39. Beaded structure on chromosomes in leptotene are: [4]

a) Centromere b) Centrosome

c) Chromomeres d) Genes
40. Which of the following stop cell division in a cell? [4]

a) Gibberellins b) Cytokinins

c) ABA d) Auxins
41. Match the Column I with Column II and choose correct option: [4]

Column I Column II

(A) Pachytene (i) Chromosomes are moved to spindle equator.

(B) Zygotene (ii) Centromere splits and chromatids are separated.

(C) Anaphase (iii) Pairing between homologous takes place.

(D) Metaphase (iv) Crossing between homologous chromosomes,

a) A - (iii), B - (iv), C - (ii), D - (i) b) A - (iv), B - (iii), C - (ii), D - (i)

c) A - (iii), B - (ii), C - (iv), D - (i) d) A - (i), B - (ii), C - (iii), D - (iv)


42. Which of the following is true for G2-phase? [4]

a) Amount of chromosome per cell doubles. b) Cell is metabolically inactive and


continuously not grows but replicates its
DNA.

c) Proteins are synthesised in preparation for d) Amount of DNA per cell doubles.
mitosis while cell growth continues.
43. Cell doubles in size and then stops growing in: [4]

a) G2 b) Telophase

c) S d) G1

44. Four different steps that occur during meiosis are given in the following list: [4]
i. Complete separation of chromatids.
ii. Pairing of homologous chromosomes.
iii. Lining up of paired chromosomes on equator.
iv. Crossing over between chromatids.
These steps would occur in the order

a) (ii), (i), (iii), (iv) b) (ii), (iv), (iii), (i)

c) (iii), (ii), (iv), (i) d) (i), (ii), (iv), (iii)


45. Mitotic spindle attached with kinetochore of centromere is: [4]

a) End of metaphase b) Starting of metaphase

c) Starting of prophase d) End of prophase


46. In mitosis centromere divides at: [4]

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a) Both Anaphase and Telophase b) Telophase

c) Metaphase d) Anaphase
47. Which of the following statements are true for prophase? [4]
i. Initiation of condensation of chromosomal material.
ii. The centriole begins to move towards opposite poles of the cell.
iii. Chromosomes are seen and composed of two chromatids attached together at the centromere.
iv. Initiation of the assembly of mitotic spindle, the microtubules.
v. Cells at the end of prophase, do not show golgi complexes, endoplasmic reticulum, nucleolus and the nuclear
envelope.
vi. Spindle fibres attach to kinetochores of chromosomes.

a) All except (vi) b) (i), (ii), (iv) and (v)

c) (i), (ii),(iii), (v) and (vi) d) (i), (ii) and (iii)


48. Match the entities in Column I with their character in Column II regarding cell cycle: [4]

Column I Column II

(A) Leptotene (i) Terminalisation of chiasmata

(B) Zygotene (ii) Formation chiasmata

(C) Pachytene (iii) Synapsis

(D) Diplotene (iv) Chromosomes become gradually visible

(E) Diakinesis (v) Crossing over

a) A - (iii), B - (iv), C - (v), D - (ii), E - (i) b) A - (iv), B - (iii), C - (ii), D - (v), E - (i)

c) A - (iv), B - (v), C - (iii), D - (i), E - (ii) d) A - (iv), B - (iii), C - (v), D - (ii), E - (i)
49. A diploid somatic cell can divide by: [4]

a) Mitosis but not meiosis b) Meiosis but not mitosis

c) Meiosis or mitosis d) Amitosis only


50. During anaphase - I of meiosis: [4]

a) Sister chromatids separate b) Non - homologous autosomes separate

c) Non - sister chromatids separate d) Homologous chromosomes separate


51. Which of the following is not a characteristic feature during mitosis in somatic cells? [4]

a) Disappearance of nucleolus b) Synapsis

c) Spindle fibres d) Chromosome movement


52. Most active phase in cell division is: [4]

a) S phase b) Metaphase

c) Anaphase d) Telophase
53. The mandatory combination responsible for assembly of microtubules are [4]

a) Cl- and Ca2+ b) Na+ and K+

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c) Mg2+ and Ca2+ d) Na+ and Ca2+

54. Which of the following statements is false regarding cell division? [4]
i. The interphase lasts more than 95% of the duration of cell cycle.
ii. The M-phase starts with the nuclear division, corresponding to the separation of daughter chromosomes.
iii. The M-phase usually ends with division of cytoplasm.
iv. Resting phase, is the time during which the cell is preparing for division by undergoing both cell growth and
DNA replication in an orderly manner.
v. Human cell, cell division proper lasts for only about an hour.
vi. Cell division in yeast completed in about 90 minutes.

a) Only (v) b) (i), (ii) and (iii)

c) (v) and (vi) d) (iv) and (v)


55. In animal cell cytokinesis occurs by: [4]

a) Cell plate formation b) Both Cell furrow formation and Cell plate
formation

c) Cytokinesis not occurs after karyokinesis d) Cell furrow formation


56. Diploid chromosome number is 8. What shall be the number of chromatids in each daughter cell after meiosis - [4]
I?

a) 16 b) 8

c) 4 d) 2
57. G1, S, G2 are stages of: [4]

a) Interkinesis b) Meiosis

c) Interphase d) Prophase - I
58. Anastral mitosis is found in: [4]

a) Animals b) Plants

c) All living cells d) Prokaryotes


59. Meiosis in higher plants can be studied in: [4]

a) Spore mother cell b) Microspore

c) Another cell wall d) Megaspore


60. The decision of cell division occurs in: [4]

a) G2 b) S

c) G1 d) Not known

61. Bivalent or tetrad start forming in: [4]

a) Diplotene b) Leptotene

c) Zygotene d) Pachytene
62. Given: [4]
i. Chromatid

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ii. Monod
iii. Dyad
iv. Daughter chromosome
The correct sequence in cell division is:

a) iii, ii, i, iv b) ii, iii, i, iv

c) i, ii, iii, iv d) iv, iii, ii, i


63. A cell at telophase stage is observed by a student in a plant brought from the field. He tells his teacher that this [4]
cell is not like other cells at telophase stage. There is no formation of cell plate and thus the cell is containing
more number of chromosomes as compared to other dividing cells. This would result in:

a) Polyploidy b) Polyteny

c) Aneuploidy d) Somaclonal variation


64. When synapsis is complete all along the chromosome, the cell is said to have entered a stage called [4]

a) Diplotene b) Zygotene

c) Diakinesis d) Pachytene
65. The number of DNA in chromosome at G2 stage: [4]

a) One b) Eight

c) Two d) Four
66. Which of the following statements are true regarding interphase? [4]
i. It divided into G1, G2 and S-phase
ii. During G1-phase the cell is metabolically active and continuously grows but does not replicate its DNA.
iii. During S or synthesis phase DNA synthesis or replication takes place.
iv. If the initial amount of DNA is denoted as 2C then it increases to 4C.
v. There is a doubling in the chromosome number.
vi. Initial amount of chromosome is denoted as 2n then it increases to An.

a) (i), (ii), (iii) and (iv) b) (i), (ii) and (iii)

c) (i), (ii), (iii), (v) and (vi) d) (i), (ii), (iv) and (v)
67. The stage during which separation of the paired homologous chromosomes begins is: [4]

a) Diplotene b) Zygotene

c) Diakinesis d) Pachytene
68. Identify the correct statement with regard to G1 phase (Gap 1) of interphase. [4]

a) Reorganisation of all cell components takes b) DNA synthesis or replication takes place.
place.

c) Cell is metabolically active, grows but does d) Nuclear Division takes place.
not replicate its DNA.
69. In eggs or oocytes, active period of growth and metabolism is: [4]

a) Pachytene b) Zygotene

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c) Leptotene d) Diplotene
70. When cell has stalled DNA replication fork, which checkpoint should be predominantly activated? [4]

a) G2/M b) G1/S

c) M d) Both G2 / M and M

71. Colchicine prevents the mitosis of cell at: [4]

a) Anaphase stage b) Metaphase stage

c) Telophase stage d) Prophase stage


72. Longest stage in M - phase of cell cycle is: [4]

a) Interphase b) Prophase

c) Metaphase d) Telophase
73. Which of the following is the time during which the cell is preparing for division by undergoing both cell growth [4]
and DNA replication in an orderly manner?

a) Interphase b) Cytokinesis

c) S - phase (Synthesis) d) Karyokinesis


74. How many statements are wrong regarding the synthesis phase? [4]
i. Period during which DNA synthesis or replication takes place.
ii. During this time the amount of DNA per cell not changes.
iii. If the initial amount of DNA is denoted as 2 C then it increases to 4C.
iv. No increase in the chromosome number.
v. Centriole duplicates in the cytoplasm.
vi. It is a quiescent stage.

a) Five b) Three

c) Two d) One
75. The specialized organ/organs for the study of meiosis is/are: [4]

a) Nucellus b) Embryo

c) Both Embryo and Pollen sac d) Pollen sac

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