L01. BP405T History, Scope and Development of Pharmacognosy

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Contents

Definition and history of Pharmacognosy

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Objectives

• At the end of this tutorial, student will be able to

– Define Pharmacognosy

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– Describe the evolution of Pharmacognosy

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Definition
Pharmacognosy (Materia Medica)

Pharmacognosy = “Pharmakon
Pharmakon” + “Gignosco”

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Drug To acquire knowledge about

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• Analecta Pharmacognostica by C A Seydler


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Definition

 Objective study of crude drugs from natural sources, treated scientifically and
it encompasses the knowledge of the history, distribution, cultivation,
collection, processing for market and preservation, the study of sensory,

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physical, chemical and structural characters and uses of crude drugs

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 Simultaneous application of various scientific disciplines with the object of

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acquiring knowledge about the drugs from every point of view
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 Applied science which deals with the biologic,


biologic biochemical and economic
features of the natural drugs and its constituents

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History

 Plants - medicinally in China, India, Egypt, Greece, etc

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Western Medicine

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Unani

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Ayurvedic

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Orient
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Histo
ory
Prehistoric Evidence
 Archaelogical studies

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 Neanderthal men (60, 000 B.C)

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New Stone Age (8000-5000 B.C.)

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 Paleolithic (food gathering) to Neolithic (food producing) period
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 Lake dwelling people


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Eg., Papaver somniferum, Verbana officinalis, Fumaria officinalis


 Medicine - rituals

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Histo
ory
Ancient Mesapatomia
 Sumerians, Cuneiform writing
 About 660 tablets (650 B.C) from the Ashurbanipal’s Library at Ninevah,

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now in British museum

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 Treatise of Medical Diagnosis and prognoses

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 Practitioners were of two types

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Ashipu: (sorcerer) diagnose the ailments
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Asu: (Physician) Specilised in herbal medicine

 Decoctions

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Ancient Egypt Histo
ory
Papyrus Ebers (1600 B.C.)
 Tomb of Mummy
 More than 800 formulae / 700 different drugs

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 Embalming the dead body

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Edwinsmith Papyrus (1600 B.C)


 Surgical instructions, formula for cosmetics

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Histo
ory
Ancient China
 “Pen-t-Sao” by Shen-Nung in 3000 B.C. contained about 365 drugs

 One a day for a year

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120 emperor drugs

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120 minister herbs

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125 servant herbs

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 Bencao Gangmu or The Compendium of Materia


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Medica, 1578 by Li Shi Zhen


 1898 crude drugs of plant, animal, mineral origin

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Histo
ory
Ancient India
 Ayurveda - “Ancient Science of Life” [ space, air, energy, liquid and solid]

 “Gunas”

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 “Charaka” ; 50 groups with 10 herbs in each group

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 “Sushruta” ; 760 herbs in 7 sets based on common properties

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 “Charaka Samhita” (Medicinal plants); “Sushruta Samhita” (Surgery)
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Histo
ory
Ancient Greece and Rome

 Earliest of Greek medical knowledge is “Homer”


 Iliad and the Odyssey,
Odyssey dates around 8th century B.C

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 Iliad - treatment of injuries

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Hippocrates, Father of Medicine (460-360
( B.C),
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first natural doctor, used simple natural remedies


like vinegar, honey, etc

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Histo
ory
 Theophrastus
 Father of Botanical Sciences
 De histori Plantarum

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 Dioscorides (40-80
(40 AD)

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 Materia Medica

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 Galen (131-200 AD
 Method of preparing the formulae
 Galenical Pharmacy
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Histo
ory
Middle Ages
 Schools of medicines
 Avicenna - Ash-Shifa (Book of Healing) and Canon of Medicine

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 Monastic Pharmacy

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Histo
ory
The Renaissance:
 Ortus Sanitatis (Garden of health), Latin in 1491
 Older German book Herbarius Zu Teutsch

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 Standard book of medicine in England during 16th century

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 De Histori Stirpium by Leonhurt Fuchs in

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1542 en
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 A New Herball, by William Turner in 1551


 Ortus Sanitatis and Ye Grete Herball
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Summa
mmary
• Pharmacognosy is derived from two Greek words
• Pharmacognosy is the study of crude drugs obtained from plants,
animals and minerals

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• Neanderthal men fortified plants along with dead bodies in the

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burial site

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• Sumerians developed cuneiform writing and contributed Treatise of

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Medical Diagnosis and prognoses
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• Papyrus Ebers and Edwinsmith Papyrus were the important


contribution by Egyptians
• Chinese contributed Pen-t-Sao and Bencao Gangmu
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Summary
• Charaka and Sushruta contributed Charaka Samhita (medicine) and
Sushruta Samhita (surgery) respectively
• Astanga Hrdya Samhita was also contributed by Indians

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• Homer, Hippocrates, Theophrastus, Dioscorides and Galen from Rome

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and Greece made important contributions to the development of

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Pharmacognosy

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• During middle ages, several schools
sch of medicines originated and
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Avicenna was an important contributor

• In the Renaissance period books were compiled, written and printed

• During modern times several pure phytochemicals were isolated


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