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Tripathy - Summary of Drugs Affecting Blood and Blood Formation
Tripathy - Summary of Drugs Affecting Blood and Blood Formation
COAGULANTS
Coagulants are substances that helps to enhance coagulation that is very useful
in bleeding conditions. Clotting factors that are involved in blood coagulation
are naturally found in Fresh whole blood or Fresh frozen plasma , however
these clotting factors acts immediately in response to haemorrhage. Drugs that
causes blood coagulation are :
VITAMIN K
k1: Phytonadione
(Phylloquinone)
k2 : Menadione
Acetamenaphthone
Menadione sodium
bisulfite
COAGULANTS
MISCELLANEOUS
Fibrinogen (human)
Antihaemophilic factor
Desmopressin
Adrenochrome mono
-semicarbazone
Ethamsylate
Rutin
INTRINSIC PATHWAY EXTRINSIC PATHWAY
XIIIa THROMBIN
FIBRIN (insoluble)
[TF III – Tissue factor, Ca++ ions are responsible for the activation of several
coagulation factors ]