Name of Drug Mechanism of Action Indication Contraindication Adverse Reaction Nursing Responsibilities

Generic name: Inhibits proton pump activity by binding to Maintenance of healing of erosive  Contraindicated in patients CNS: BEFORE:
Pantoprazole hydrogen-potassium adenosine esophagitis hypersensitive to any anxiety, dizziness, headache, - Instruct patient about the route, frequency and
triphosphatase,located at secretory surface competent of the insomnia, migraine, depression, mechanism of action of the medication.
Brand name: vertigo.
of gastric parietal cells, to suppress gastric formulation.
Pantoloc CV: -Instruct the patients about the possible side effect of
acid secretion. Short-term treatment of erosive  There are no adequate the drug such as headache, diarrhea, abdominal pain,
esophagitis associated with GERD studies in pregnant women. chest pain, edema,
Classification: and nausea
Antiulcer Drugs Use cautiously and only if thrombophlebitis
Long-term maintenance of healing clearly needed EENT: -before giving pantoprazole ensure that monitor for
Dose Frequency: erosive esophagitis and reduction in blurred vision rhinitis, sinusitis, magnesium level (Prolonged use of PPIs may cause
 Drug appear in human milk.
40mg/vial GI: low magnesium levels).
relapse rates of daytime and Pt should discontinue
(Once a day) Abdominal pain, constipation,
nighttime heartburn symptoms in breastfeeding or DURING:
patients with GERD. discontinue drug. diarrhea, gastroteritis
Route: - Monitor patient for signs and symptoms of low
Respiratory: magnesium level, such as abnormal HR or rhythm
PO Bronchitis, dyspnea, increased palpitations, muscle spasms. tremors or seizures
Onset: 15-30 min cough.
Peak: Unknown GU: AFTER:
Duration>24 hours Urinary frequency.
-Advise patient that drug can be taken wit out regard
to meals.
IV -Tell patient that antacids don’t affect drug
Onset: 15-30 min absorption.
Peak: Unknown -Teach patient to report all adverse reactions and to
Duration>24 hours recognize and report signs and symptoms of low
magnesium
Half-life: 1 Hour
 Name of Drug Mechanism of Action Indication Contraindication Adverse Reaction Nursing Responsibilities

BEFORE:
Generic name: May inhibit prostaglandin Short-term management of moderately  Drug is contraindicated in patients who CNS: Dizziness, drowsiness, - check the doctor’s order
Keterolac synthesis to produce anti- severe, acute pain for single-dose have previously demonstrated tremors, seizures -Assess for the patency of the IV line
inflammatory, treatment. hypersensitivity to ketorolac or allergic CV: -review the purpose and importance if the drug
Brand name: manifestations to aspirin or other NSAIDs. Hypertension, flushing, -protect drug vials from light
analgesis,and antipyretic
Toradol Short-term management of moderately  Contraindicated for treatment of syncope, pallor, edema,
effects. severe, acute pain when switching from vasodilatation. DURING
preoperative pain in patients requiring
Classification: parenteral to oral administration(Oral CABG surgery. EENT:
NSAIDs therapy is indicated only as continuation  Contraindicated in pt. currently receiving Tinnitus, hearing loss, blurred -check the drug’s label twice
of parenterally given drug and should aspirin, probenecid, risk of inducing serious vision, transient
Dose Frequency: never be given without patient first NSAID-related adverse reactions. burning/stinging AFTER:
40mg/vial having received parental therapy. GI: Nausea, anorexia, vomiting,
(Once a day) diarrhea, constipation, -Monitor V/s
-report sore throat ,fever, rash, itching ,weight
Route: gain ,swelling in ankles or fingers, changes in vision;
-document the record
PO
Onset: 30-60 min
Peak: 2-3 hr
Duration:4-6 hr

IV,IM
Onset: 30 min
Peak:2-3 hr.
Duration:4-6 hr

Half-life:
PO, 2 to 9 hours; IV 5 to 6
hours;IM,5 to 6 hours;intrasal,5
to 6 hours
 Name of Drug Mechanism of Action Indication Contraindication Adverse Reaction Nursing Responsibilities

 Contraindicated for the treatment of

Generic name: Though to inhibit Nonsteroidal anti-inflammatory drug perioperative pain after CABG. CNS: headache, dizziness, BEFORE:
Celecoxib prostaglandin synthesis, (NSAID) used to treat mild to moderate  Contraindicated in patients hypersensitive insomnia - Instruct patient about the route, frequency and
pain and help relieve symptoms of to drug, sulfonamides, aspirin, or other CV: mechanism of action of the medication.
impeding cyclooxygenase-
Brand name: (arthritis, osteoarthritis ,rheumatoid NSAIDS. HTN, peripheral edema.
Celebrex 2,to produce anti- arthritis) such as inflammation, swelling, EENT: pharyngitis, rhinitis, -Instruct the patients about the possible side effect of the
 Contraindicated in patients who
inflammatory, analgesic, stiffness and joint pain experience asthma, urticarial, or allergic- sinusitis drug.
Classification: and antipyretic effects. type reactions to sulfonamides. GI:
Cyclooxygenase-2 inhibitors  Serious skin reactions (SJS, toxic epidermal Abdominal pain, diarrhea, GI - Assess patient’s eyes: redness, swelling, tearing, itching
necrolysis) can occur. Discontinue drug at reflux, nausea
Dose Frequency: first sign of rash. METABOLIC: -Monitor for pain: type, location, intensity, ROM before
 NSAIDs can increase the risk of heart attack Hyperchloremia and 1 hr. after treatment
Route: or stroke in patients with or without heart MUSCULOSKELETAL:
disease or risk factors for heart disease. Back pain
PO  Use during pregnancy isn’t recommend RESPIRATORY: DURING:
Onset: unknown because NSAID use dose to conception Dyspnea, URL -stabilize IV catheter to minimize thrombophlebitis.
Peak: 3 hr may be associated with an increased risk of SKIN: Monitor site closely
Duration: unknown miscarriage, and use 30 weeks’ gestation Erythema multiform, exfoliate
and later may cause premature closure of dermatitis, AFTER:
Half-life: the ductus arteriosus and other life- CV: - Teach patient that product must be continued for
11 hours. threating fetal conditions. thrombotic events, MI, stroke prescribed time to be effective; to avoid aspirin, alcoholic
EENT: beverages, other NSAIDs, acetaminophen
Tinnitus, hearing loss, blurred
vision, transient - Caution patient to report bleeding, bruising, fatigue,
burning/stinging malaise, since blood dyscrasias do occur
GI: Nausea, anorexia, vomiting,
diarrhea, constipation, - Instruct patient to take with a full glass of water to
flatulence enhance absorption

- Caution patient that this product may cause eye

redness, burning if soft contact lenses are worn

- Advise to report use to all health care providers, not to

use with other products unless approved by prescriber;
use for #5 days
 Name of Drug Mechanism of Action Indication Contraindication Adverse Reaction Nursing Responsibilities

Indicated for the relief of mild to Hypersensitivity or allergy Loss of appetite nausea, or vomiting Before:
Generic name: Primarily inhibit the synthesis of moderate fever paracetamol stomach cramps or pain, swelling -Establish rapport
Paracetamol prostaglandins, which are chemical pain or tenderness in the upper -Monitor the temperature
Brand name: messengers involved in the regulation of abdomen or stomach area. -Assess patient medical history
Panadol
body temperature
During
Classification: -Report abdominal pain, jaundice, dark urine
Antipyretic

Dose Frequency: After:

300 mg Advise patient to report any unusual side
Route: effects.
 Name of Drug Mechanism of Action Contraindication Adverse Reaction Nursing Responsibilities
Indication

 Determine history of hypersitivity

Generic name: Inhibits cell-wall synthesis, promoting To treat bone and joint infections  Contraindicated in patients CV: reaction to cephalosphorins,pensillins
Cefuroxime osmotic instability; usually bactericidal. hypersensitive to drug or phlebitis, thrombophlebitis and history of allergies particulary to
other cephalosporin. drug before therapy is initiated.
GI:
Brand name:  Use cautiously in patients
Zinacef Diarrhea, Pseudomembranous
hypersensitive to penicillin  Report onselt of loose stools
because of possibility pf colitis, nausea, vomiting
Classification: cross-sensitivity with other Hematologic:  Absorption of cefuroxime is enchancec
Antibiotic beta-lactam antibiotics. Hemolytic anemia, by food
 Use cautiously in patients thrombocytopenia, transient
Dose Frequency: with history of colitis and in neutropenia.  Notify prescriber about rashes or
those with renal superinfection
Skin: Maculopapular, urticarial, pain,
Route: insufficiency.
in duration ,tissue sloughing at IM
 Some products may contain
PO phenylalanine or sodium. injection site.
Onset: unknown
Peak: 2-4 hr.
Duration: unknown

IV
Onset: Immediate
Peak: 2-3 min
Duration: unknown

IM
Onset: Unknown
Peak:15-60 min
Duration: Unknown

Half-life: 1-2 hours.