Brooker Genetics 6e Chapter 04 Test Bank - Version1

Student name:__________
TRUE/FALSE - Write 'T' if the statement is true and 'F'

if the statement is false.
1) Male-pattern baldness is only an autosomal dominant
trait in humans.
⊚ true
⊚ false
Mendelian inheritance pattern

Question Details Accessibility : Keyboard
Section : 04.01 Navigation
Bloom's : 2. Understand Gradable : automatic
Topic : Overview of Simple Inheritance Patterns
Learning Outcome : 04.01.01 Compare and contrast the different types of
2) In an epistatic interaction, the genes must be located

on the same chromosome.
⊚ true
⊚ false
molecular mechanisms of
Question Details epistasis, com
Bloom's : 2. Understand Accessibility : Keyboard
Topic : Gene Interactions Gradable : automatic
Learning Outcome : 04.09.03 Describe examples that explain the
3) Typically, a recessive allele increases the expression

of a functional protein.
⊚ true
⊚ false
follow a recessive pattern of

Learning Outcome : 04.02.02 Explain why loss-of-function alleles often
Version 1 1
4) Incomplete dominance is an example of blending of phenotypes, not genotypes.
⊚ true
⊚ false
mechanisms of incomplete
Question Details dominance, over
Topic : Incomplete Dominance, Overdominance, and Codominance Gradable : automatic
Learning Outcome : 04.04.02 Explain the underlying molecular
5) Human blood groups are determined by antigens on

the surface of red blood cells.
⊚ true
⊚ false
6) Incomplete penetrance indicates that individuals who

possess a dominant trait always express the trait.
⊚ true
⊚ false
penetrance and vary in their

Bloom's : 2. Understand Navigation
Section : 04.04 Gradable : automatic
Topic : Dominant and Recessive Alleles
Learning Outcome : 04.02.03 Describe how alleles can exhibit incomplete
7) Variable expressivity means that the phenotype of a

trait can vary between individuals.
⊚ true ⊚ false
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8) Paralogs are often functionally redundant and can

compensate for the loss of either of the paralogs in a set.
⊚ true
⊚ false
9) In codominance, both alleles make functional gene

products which are expressed simultaneously.
⊚ true
⊚ false
10) In sex influenced traits, both sexes can express the

trait, depending on their genotype, but in sex limited
inheritance a particular sex can only have one phenotype for
the trait in question.
⊚ true
⊚ false
Question Details
Version 1 3
Topic : Sex-Influenced and Sex-Limited Inheritance Gradable : automatic
Learning Outcome : 04.06.01 Compare and contrast sex-influenced
inheritance and sex-limited inheritan
MULTIPLE CHOICE - Choose the one alternative that to be beneficial to the

best completes the statement or answers the question. organism, are called
11) Genes that are not required for survival, but are likely _________.
E) conditional
A) essential genes lethal alleles
B) lethal alleles
C) semilethal alleles
D) nonessential genes

12) Temperature-sensitive alleles that kill an organism

only in a particular temperature range are examples of _____.
E) conditional
A) essential genes lethal alleles
B) lethal alleles
D) nonessential genes
Accessibility : Keyboard
Question Details Navigation
Section : 04.07
Topic : Lethal Alleles
Learning Outcome : 04.07.01 Describe the different types of lethal alleles.
Version 1 4
E) environmental
A) lethal alleles effects
B) epistasis
D) recessive inheritance
Bloom's : 1. Remember Gradable : automatic
Section : 04.07
Learning Outcome : 04.07.01 Describe the different types of lethal alleles.
14) A heterozygote possesses a phenotype that is

intermediate between the homozygous dominant and
homozygous recessive phenotypes. This is most likely an
example of ________.
D) sex-influenced
A) lethal alleles inheritance
B) incomplete dominance
C) gene dosage
15) In four-o'clock plants, red flower color is dominant to

white flower color. However, heterozygous plants have a pink
color. If a pink-flowered plant is crossed with a white-
flowered plant, what will be the phenotypic ratios of their
offspring?
D) ½ pink, ½
A) ¼ red, ½ pink, ¼ white white
B) All pink E) ½ red, ½ pink
C) All white
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incomplete dominance,
Question Details overdomina
Bloom's : 3. Apply Accessibility : Keyboard
Learning Outcome : 04.04.01 Predict the outcome of crosses involving
16) The coat characteristics of arctic foxes and Siamese

cats, where proteins in the extremities function differently
than in other parts of the body, is an example of _________.
E) None of the
A) incomplete dominance answers are correct
B) multiple allele systems
D) temperature-sensitive allele
regard to an individual’s
Topic : Environmental Effects on Gene Expression
Learning Outcome : 04.03.01 Discuss the role of the environment with
17) In rabbits, full coat color (c) is the dominant trait. A

second allele, chinchilla (c ch) is recessive to full coat color.
Himalayan coat color (c h) is recessive to chinchilla and full
coat colors and albino (c) is recessive to all coat colors. If two
chinchilla rabbits mate, what coat color is not possible in their
offspring?
E) All coat colors

A) Full coat color are possible
B) Chinchilla coat color
C) Himalayan coat color
D) Albino coat color
Bloom's : 4. Analyze
Question Details Section : 04.04
Version 1 6
Topic : Incomplete Dominance, Overdominance, and Codominance Accessibility : Keyboard
Learning Outcome : 04.04.01 Predict the outcome of crosses involving Navigation
incomplete dominance, overdomina Gradable : automatic
18) In human blood groups, the fact that an individual can

have an AB blood type is an example of ___________.
D) temperature-
A) incomplete dominance sensitive conditional allele
B) incomplete penetrance E) codominance
C) sex-influenced trait
Bloom's : 1. Remember Accessibility : Keyboard
19) An individual with type A blood and an individual is not possible in their
with type B blood mate and have offspring. What blood type offspring?
E) All blood types

A) Type O blood are possible
B) Type A blood
C) Type B blood
D) Type AB blood
incomplete dominance,
Question Details overdomina
20) At the molecular level, type A and type B blood differ

in which of the following characteristics?
A) The antigens
Version 1 7
present on the surface of the red blood cells D) All of the
B) The type of sugar found in each type answers are correct
C) The antibodies that are generated against the other
type of blood
21) For a certain trait, a heterozygous individual has a

selective advantage as compared to a homozygous dominant
or homozygous recessive individual. This is called ________.
E) multiple allele
A) codominance systems
C) overdominance
D) incomplete penetrance
22) Humans homozygous for the sickle cell allele have

sickle cell anemia. A human that is heterozygous for the
sickle cell allele is an example of _____________.
D) multiple allele
A) codominance systems
B) incomplete penetrance
C) heterozygous advantage
Question Details
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incomplete dominance, overdomina
23) At the molecular level, which of the following best

explain heterozygous advantage and overdominance?
D) Infectious
A) A heterozygous individual can produce more organisms may recognize
varieties of homodimer proteins only a specific functional
B) The alleles produce two different proteins with protein
slightly different functions E) All of the
C) The proteins produced by the alleles may provide answers are possibilities
a broader range of environmental tolerance, such as
temperature ranges
24) An individual carries the allele for polydactyly, but is

normal. This is an example of __________.
D) codominance
A) simple Mendelian inheritance E) gene dosage
C) incomplete penetrance

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allele(s) for a trait express
A) Individuals with the trait show variation in the trait.
expression. D) The trait is
B) It is lethal in 30% of the individuals who have the present in 70% of the
trait. population.
C) Only 70% of the individuals who carry the

26) Phenylketonuria in humans is an example of

__________.
D) incomplete
A) incomplete penetrance dominance
B) codominance
C) an environmentally-influenced trait
regard to an individual’s
Topic : Environmental Effects on Gene Expression
Learning Outcome : 04.03.01 Discuss the role of the environment with
27) If an allele is dominant in one sex and recessive in

another, it is an example of ___________.
D) simple
A) sex-limited inheritance Mendelian inheritance
B) sex-influenced inheritance
C) incomplete dominance

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28) A woman who is heterozygous for an allele that
results in X-linked pattern baldness marries a man who is
nonbald. Which of the following would be true of their
offspring?
D) ½ of females
A) All would be bald would be bald, and ½ of
B) All of the females would be nonbald, all males the males would be bald
would be bald E) All would be
C) All of the females would be nonbald, ½ of the nonbald
males would be bald
influenced inheritance.
Bloom's : 3. Apply Navigation
Topic : Sex-Influenced and Sex-Limited Inheritance
Learning Outcome : 04.06.02 Predict the outcome of crosses for sex-
29) A paralog ____________.
E) has the same

A) is found for every gene in mammals DNAsequence as the
B) is only found on the X but not the Y chromosome original duplicated gene
C) can explain the lack of phenotype for a gene
knockout
D) cannot be mutated
30) The interaction of two genes to produce a phenotype

was first described by __________.
A) Morgan and
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Bridges E) None of the
B) Mendel answers are correct
C) Darwin
D) Bateson and Punnett
Section : 04.08
Topic : Pleiotropy
Learning Outcome : 04.08.01 Explain the phenomenon of pleiotropy.
31) Epistasis is _______________.
the same individual

A) another term for overdominance E) None of the
B) when one gene can mask the expression of a answers are correct
second gene
C) a trait that is only expressed in one sex of the
species
D) when two dominant alleles can be expressed in
32) In a dihybrid cross of two heterozygous individuals,

you expect a 9:3:3:1 phenotypic ratio in the offspring, but
observe a ratio of 9:7. What is the most likely explanation?
E) Epistatic
A) Codominance interaction of the two
B) It is a sex-limited trait genes
C) Simple Mendelian inheritance
D) Incomplete penetrance
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epistasis, complementation,
Question Details gene
33) Which of the following is not correct concerning

epistatic interactions?
D) They always
A) They can be associated with enzymatic pathways. result in a 9:7 ratio of a
dihybrid cross.
B) They produce variations in the expected 9:3:3:1 E) They are due to
ratio of a dihybrid cross. gene interactions.
C) They can result when a gene at one locus masks
the expression of a gene at a different locus.
34) When wild-type offspring are produced from a cross

between parents that both display the same recessive
phenotype, this illustrates the genetic phenomenon of
_______.
D) gene dosage
A) simple recessive alleles E) a spontaneous
B) incomplete penetrance mutation
C) complementation
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35) The multiple effects of a single gene on the phenotype
of an organism is called _______.
D) overdominance
A) epistasis E) pleiotropy
B) penetrance
C) expressivity
Section : 04.08
Topic : Pleiotropy
Learning Outcome : 04.08.01 Explain the phenomenon of pleiotropy.
36) A ______ allele is the most prevalent allele in a proper amount and
population and usually encodes a protein that is made in the functions normally.
D) gain-of-
A) loss-of-function function
B) mutant E) lethal
C) wild-type
polymorphism.
Learning Outcome : 04.02.01 Define wild-type allele and genetic
37) In overdominance, the _______ genotype is beneficial

over the _______ genotypes.
E)
A) heterozygous,homozygous incompletedominant,
B) homozygous,heterozygous codominant
C) homozygousdominant, homozygous recessive
D) homozygousrecessive, homozygous dominant
Topic : Incomplete Dominance,

Question Details Overdominance, and
Bloom's : 2. Understand Codominance
Section : 04.04 Learning Outcome : 04.04.01
Version 1 14
Predict the outcome of crosses involving incomplete dominance, Accessibility : Keyboard
overdomina Navigation
Gradable : automatic
38) In cattle, the presence or absence of scurs follows a

sex-influenced pattern of inheritance. A heterozygous male
has _______ and a heterozygous female has _______ .
D) scurs, no scurs
A) Y-linked, X-linked
B) no scurs, scurs
C) X-linked, Y-linked
influenced inheritance.
Topic : Sex-Influenced and Sex-Limited Inheritance
Learning Outcome : 04.06.02 Predict the outcome of crosses for sex-
39) If a combination of two or more genes is required to

produce a specific trait, it is called a(n) _______.
D) sex-linkedtrait
A) overdominance E) geneinteraction
B) simple mendeliantrait
C) sex-influencedtrait
Learning Outcome : 04.09.01

Question Details Define gene interaction.
40) How did Bateson and Punnett's work with comb

morphology in chickens differ from the dihybrid work of
Mendel?
B) Their F2
A) They were working with sex-limited traits. offspring displayed 4
Version 1 15
unique phenotypes, not the four combinations of two environment in which the
phenotypes expected in a Mendelian cross. chickens were raised.
C) ½ of their combinations were lethal.
D) The expression of their trait varied by the

Question Details Define gene interaction.
41) The trait of cream-colored eyes in Drosophila is an

example of ________.
D) gene dosage
A) simple recessive alleles E) a spontaneous
B) incomplete penetrance of red eyes mutation
C) a gene modifier effect in eye color
42) The presence of a group of antigens that determine

blood type is an example of a(n) ____________.
D)
A) semilethalallele incompletedominance
B) sex-linkedtrait
C) multiple allelesystem

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43) If a light-eosin eye male Drosophila is crossed to a
homozygous red eyed female, what will be the phenotype of
their offspring?
light-eosin eyes.
A) All offspring will have red eyes. D) All flies will
B) All males will have light-eosin eyes and all have white eyes.
females will have eosin eye
C) All females will have red eyes, all males will have
44) Filled in circles and square show affected individuals.

Select the mode of inheritance for individual III-3.
D) X-linked
A) Incomplete dominance inheritance
B) Codominance
C) Pseudoautosomal inheritance
Bloom's : 3. Apply Gradable : automatic
Section : 04.05
Topic : X-Linked Inheritance
Learning Outcome : 04.05.02 Explain pseudoautosomal inheritance.
Version 1 17
45) Heavy metals, such as copper, are required for proper were grown in 6 different
development. However, if too much copper is present it can concentrations of copper.
lead to developmental defects. A scientist was interested in This experiment evaluates
studying the developmental defects that could occur at various a(n) _____________.
concentrations of copper. Genetically identical organisms
D) norm of
A) epistasis reaction
B) dominant trait
C) recessive trait

Question Details Define norm of reaction.
Topic : Environmental Effects on Gene Expression Gradable : automatic
46) A male Manx cat and a female Manx cat produce

kitten.What is the probability that kitten has a non-manx tail?
C) 1/4
A) 1/3 D) 2/3
B) 1/2
outcome of a cross.
Learning Outcome : 04.07.02 Predict how lethal alleles may affect the
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47) The pedigree below shows the inheritance pattern of a
rare X-linked allele for one family. The filled in circles and
squares show affected individuals. What is the probability of
individual III-2 being born male and affected?
C) 1/4
A) 1/2 D) 0
B) 1/3
inheritance.
Bloom's : 4. Analyze Navigation
Topic : X-Linked Inheritance
Learning Outcome : 04.05.01 Predict the outcome of crosses for X-linked
48) The pedigree below shows the inheritance pattern of a

rare X-linked allele for one family. The filled in circles and
squares show affected individuals.What is the probability of
individual III-2 being born female and affected?
C) 1/4
A) 1/2 D) 0
B) 1/3
Question Details
Version 1 19
Bloom's : 4. Analyze inheritance.
Section : 04.05 Accessibility : Keyboard
Topic : X-Linked Inheritance Navigation
Learning Outcome : 04.05.01 Predict the outcome of crosses for X-linked Gradable : automatic
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Answer Key
Test name: Chapter 04 Test Bank

1) FALSE
2) FALSE
3) FALSE
4) TRUE
5) TRUE
6) FALSE
7) TRUE
8) TRUE
9) TRUE
See Section 4.4
10) TRUE
Review Section 4.6
11) D
12) E
13) A
14) B
15) D
16) D
17) A
Version 1 21
18) E
19) E
20) D
21) C
22) C
23) E
24) C
25) C
26) C
27) B
28) C
29) C
30) D
31) B
32) E
33) D
34) C
35) E
36) C
37) A
38) D
Version 1 22
39) E
40) B
41) C
42) C
43) A
44) C
45) D
46) A
47) D
48) A
Individual II-2 carries the rare allele on the X chromosome Punnett square for a cross
because this is an X-linked allele, and also his father is not between individuals II-2
affected but his mother is affected. In addition, the allele is and II-1 shows that 50%
dominant because individual II-4 received a normal allele (1/2) of the offspring are
from her unaffected father but still displays the affected expected to be normal
phenotype because she received the rare allele from her males and 50% (1/2) of the
affected mother. Thus, individual II-1 possesses normal offspring are expected to
alleles on both X chromosomes because she is unaffected. A be affected females.
Version 1 23

Brooker Genetics 6e Chapter 04 Test Bank - Version1

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Student name:__________

TRUE/FALSE - Write 'T' if the statement is true and 'F'

Mendelian inheritance pattern

2) In an epistatic interaction, the genes must be located

3) Typically, a recessive allele increases the expression

follow a recessive pattern of

5) Human blood groups are determined by antigens on

6) Incomplete penetrance indicates that individuals who

penetrance and vary in their

7) Variable expressivity means that the phenotype of a

8) Paralogs are often functionally redundant and can

9) In codominance, both alleles make functional gene

10) In sex influenced traits, both sexes can express the

MULTIPLE CHOICE - Choose the one alternative that to be beneficial to the

Mendelian inheritance pattern

12) Temperature-sensitive alleles that kill an organism

14) A heterozygote possesses a phenotype that is

15) In four-o'clock plants, red flower color is dominant to

16) The coat characteristics of arctic foxes and Siamese

17) In rabbits, full coat color (c) is the dominant trait. A

E) All coat colors

18) In human blood groups, the fact that an individual can

E) All blood types

20) At the molecular level, type A and type B blood differ

21) For a certain trait, a heterozygous individual has a

22) Humans homozygous for the sickle cell allele have

23) At the molecular level, which of the following best

24) An individual carries the allele for polydactyly, but is

penetrance and vary in their

penetrance and vary in their

26) Phenylketonuria in humans is an example of

27) If an allele is dominant in one sex and recessive in

Mendelian inheritance pattern

29) A paralog ____________.

E) has the same

30) The interaction of two genes to produce a phenotype

31) Epistasis is _______________.

the same individual

32) In a dihybrid cross of two heterozygous individuals,

33) Which of the following is not correct concerning

34) When wild-type offspring are produced from a cross

37) In overdominance, the _______ genotype is beneficial

Topic : Incomplete Dominance,

38) In cattle, the presence or absence of scurs follows a

39) If a combination of two or more genes is required to

Learning Outcome : 04.09.01

40) How did Bateson and Punnett's work with comb

Learning Outcome : 04.09.01

41) The trait of cream-colored eyes in Drosophila is an

42) The presence of a group of antigens that determine

Mendelian inheritance pattern

44) Filled in circles and square show affected individuals.

Learning Outcome : 04.03.02

46) A male Manx cat and a female Manx cat produce

48) The pedigree below shows the inheritance pattern of a

Test name: Chapter 04 Test Bank

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