R.

K Chemistry Classes Biomolecules 10+2-2023-24

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1. The main structural feature of proteins is 𝐶𝐻𝑂 𝐶𝐻 𝑂𝐻

(1) The ester linkage | |
(2) The ether linkage (1) 2𝐶𝐻𝑂𝐻 (2) 2𝐶 = 𝑂
(3) The peptide linkage | |
𝐶𝐻 𝑂𝐻 𝐶𝐻 𝑂𝐻
(4) All of these
2. Glucose can not be classified as 𝐶𝐻𝑂 𝐶𝐻 𝑂𝐻
(1) A hexose | |
(2) A carbohydrate (3) (𝐶𝐻𝑂𝐻) (4) (𝐶𝐻𝑂𝐻)
(3) An oligo saccharides | |
(4) An aldose 𝐶𝐻 𝑂𝐻 𝐶𝐻 𝑂𝐻
3. Which of the following is an acidic amino acid? 10. Amino acids are
(1) Lysine (1) Liquids
(2) Arginine (2) Volatile solids
(3) Aspartic acid (3) Non – volatile crystalline compounds
(4) Histidine (4) Mixture of amines and acids
4. Adenine is 11. On treating glucose with Fehling’s solution we get a
(1) A nucleotide precipitate, whose colour is
(2) An enzyme (1) Yellow
(3) An amino acid (2) Red
(4) Purine base (3) Black
5. Which of the following monosaccharide is a pentose? (4) White
(1) Galactose 12. Which one of the following is not present in RNA?
(2) Glucose (1) Uracil
(3) Fructose (2) Thymine
(4) Arabinose (3) Ribose
6. The disaccharide present in milk is (4) Phosphate
(a) Maltose 13. On complete hydrolysis all proteins yield
(b) Lactose (1) 𝛼-Aminoacids
(c) Sucrose (2) Monohydric alcohol
(d) Cellobiose (3) Mono haloalkanes
7. Glucose gives silver mirror with tollens reagent tests, it (4) Enzymes
shows the presence of 14. Which of the following is correct about fructose?
(1) An acidic group (1) It has furanose structure
(2) An alcoholic group (2) It is hexose
(3) A ketonic group (3) It has open chain structure
(4) An aldehydic group (4) All of these
8. Peptides are 15. –NH – CO – group is characteristic of
(1) Esters (1) Cellulose
(2) Salt (2) Nucleic acid
(3) Amides (3) Proteins
(4) Ketones (4) Phospholipids
9. Product [P] in the following reaction will be 𝑁𝐻
𝐶𝐻 𝑂𝐻 |
| 16. An aqueous solution of 𝐶𝐻 − 𝐶𝐻 − 𝐶𝑂𝑂𝐻 at
𝐶=𝑂 isoelectric point migrates
| (1) Towards anode
\
(𝐶𝐻𝑂𝐻) ⎯⎯ [𝑃] (2) Towards cathode
| (3) No migration towards any electrode
𝐶𝐻 𝑂𝐻 (4) None of these

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17. Glucose ⎯⎯ P, Product ‘P’ is (2) The sugar component in RNA is arabinose and the
(1) Gluconic acid sugar component in DNA is 2’ –deoxyribose
(2) Glucaric acid (3) The sugar component in RNA is ribose and the
(3) Aspartic acid sugar component in DNA is 2’ –dexoyribose
(4) All of these (4) The sugar component in RNA is arabinose and the
18. Which one of the following sets of monosaccharides sugar component in DNA is ribose
forms sucrose? 22. The central dogma of molecular genetics states that the
(1) 𝛽 − 𝐷 − Glucopyranose and 𝛼 − 𝐷 − genetic information flows from
fructofuranose (1) Amino acids → Proteins → DNA
(2) 𝛼 − 𝐷 − Glucopyranose and 𝛽 − 𝐷 − f (2) DNA → Carbohydrates → Proteins
fructofuranose (3) DNA → RNA → Proteins
(3) 𝛼 − 𝐷 − Galactopyranose and 𝛽 − 𝐷 − (4) DNA → RNA → Carbohydrates
Glucopyranose 23. Which of the following compounds can form a
(4) 𝛼 − 𝐷 − Glucopyranose and 𝛽 − 𝐷 − zwitterion?
fructofuranose (1) Aniline
19. D(+) glucose reacts with hydroxyl amine and yields an (2) Acetanilide
oxime. The structure of the oxime would be (3) Glycine
𝐶𝐻 = 𝑁𝑂𝐻 𝐶𝐻 = 𝑁𝑂𝐻 (4) Benzoic acid
| | 24. Which of the following pairs represents anomers?
𝐻 − 𝐶 − 𝑂𝐻 𝐻𝑂 − 𝐶 − 𝐻
| |
𝐻𝑂 − 𝐶 − 𝐻 𝐻𝑂 − 𝐶 − 𝐻
| |
(1) 𝐻𝑂 − 𝐶 − 𝐻 (2) 𝐻 − 𝐶 − 𝑂𝐻
| |
𝐻 − 𝐶 − 𝑂𝐻 𝐻 − 𝐶 − 𝑂𝐻
| |
𝐶𝐻 𝑂𝐻 𝐶𝐻 𝑂𝐻

𝐶𝐻 = 𝑁𝑂𝐻 𝐶𝐻 = 𝑁𝑂𝐻
25. Proteins are found to have two different types of
| |
secondary structures viz. 𝛼-helix and 𝛽-pleated sheet
𝐻𝑂 − 𝐶 − 𝐻 𝐻 − 𝐶 − 𝑂𝐻
structure. 𝛼-helix structure of proteins is stabilised by:
| |
(a) Peptide bonds
𝐻−𝐶 −𝐻 𝐻𝑂 − 𝐶 − 𝐻
(b) Van der Waal’s forces
| |
(c) Hydrogen bonds
(3) 𝐻𝑂 − 𝐶 − 𝐻 (4) 𝐻 − 𝐶 − 𝑂𝐻
(d) Dipole –dipole interactions.
| |
26. Which of the following acids is a vitamin?
𝐻 − 𝐶 − 𝑂𝐻 𝐻 − 𝐶 − 𝑂𝐻
(a) Aspartic acid
| |
(b) Ascorbic acid
𝐶𝐻 𝑂𝐻 𝐶𝐻 𝑂𝐻
(c) Adipic acid
(d) Saccharic acid.
20. In a protein molecule, various amino acids are linked
27. Dinucleotide is obtained by joining two nucleotides
together by
together by Phosphodiester linkage. Between which
(1) Dative bond
carbon atoms of pentose sugars of nucleotides are these
(2) 𝛼-glycosidic bond
linkages presents?
(3) 𝛽-glycosidic bond
(a) 5’ and 3’
(4) Peptide bond
(b) 1’ and 5’
21. The correct statement regarding RNA and DNA,
(c) 5’ and 5’
respectively is
(d) 3’ and 3’
(1) The sugar component in RNA is 2’-deoxyribose
and the sugar component in DNA is arabinose

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28. Nucleic acids are the polymers of

(a) Nucleosides
(b) Nucleotides
(c) Bases
(d) Sugars.
29. Which of the following statements is not true about
glucose?
(a) It is an aldohexoses
(a) I, II, III
(b) On heating with HI, it forms n-hexane
(b) II, III
(c) It is present in furanose form
(c) I, II
(d) It does not give 2, 4-DNP test.
(d) III.
30. Each polypeptide in a protein has amino acids linked
35. Structure of a disaccharide formed by glucose and
with each other in a specific sequence. This sequence of
fructose is given below. Identify anomeric carbon atoms
amino acids is said to be
in monosaccharide units.
(a) Primary structure of proteins
(b) Secondary structure of proteins
(c) Tertiary structure of proteins
(d) Quaternary structure of proteins.
31. DNA and RNA contain four base each. Which of the
following bases is not present in RNA?
(a) Adenine (a) ‘a’ carbon of glucose and ‘a’ carbon of fructose.
(b) Uracil (b) ‘a’ carbon of glucose and ‘e’ carbon of fructose.
(c) Thymine (c) ‘a’ carbon of glucose and ‘b’ carbon of fructose.
(d) Cytosine. (d) ‘f’ carbon of glucose and ‘f’ carbon of fructose.
32. Three cyclic structures of monosaccharides are given 36. Proteins can be classified into two types on the basis of
below. Which of these are anomers? their molecular shapes i.e., fibrous proteins and globular
proteins. Which of the following is not a globular
proteins:
(a) Insulin
(b) Keratin
(c) Albumin
(a) I and II (d) Haemoglobin.
(b) II and III
(c) I and III 37. Lysine, 𝐻 𝑁 − (𝐶𝐻 ) − 𝐶𝐻 − 𝐶𝑂𝑂𝐻 is
(d) III is anomers of I and II. |
33. Which of the following reactions of glucose can be 𝑁𝐻
explained only by its cyclic structure?
(a) 𝛼-Amino acid
(a) Glucose forms Pentaacetate
(b) Basic amino acid
(b) Glucose reacts with hydroxylamine to form an
(c) Essential amino acid
oxime
(d) All of these.
(c) Pentaacetate of glucose does not react with
38. Which of the following is a purine base?
hydroxylamine
(a) Guanine
(d) Glucose is oxidised by nitric acid to gluconic acid.
(b) Cytocine
34. Optical rotation of some compounds along with their
(c) Thymine
structures are given below. Which of them have D-
(d) Uracil
configuration?
39. The process by which protein synthesis takes place is
based on genetic information called
(a) Replication
(b) Messenger hypothesis
(c) Translation
(d) Transcription.

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40. Mutarotation does not occur in: (b) (1) and (3)
(a) Sucrose (c) (1) and (2)
(b) D-glucose (d) (1), (2) and (3).
(c) L-glucose 49. Identify the sequence of base of mRNA molecule
(d) None of these. synthesised on the given strand
41. 𝛼-D(+) glucose and 𝛽-D(+) glucose are AGCGATTAC
(a) Enantiomers (a) ACGCATTAG
(b) Geometrical isomers (b) TGGCTAATG
(c) Epimers (c) UCGCUAAUG
(d) Anomers. (d) UCGCUTTUC.
42. Which of the following is not a protein? 50. Which of the following 𝛼-amino acids has a phenolic
(a) Wool ( - OH ) group in the back bone?
(b) Nail (a) Phenylatanine
(c) Hair (b) Histidine
(d) Fat. (c) Tyrosine
43. Which of the following is a protein? (d) Glumatic acid.
(a) Lectihin 51. Naturally occurring sugars and amino acids have
(b) Glycogen configuration respectively,
(c) Keratin (a) L-sugars, D-amino acids
(d) Lysine. (b) D-sugars, D-amino acids
44. Which exists as a Zwitter ion? (c) D-sugars, L-amino acids
(a) Urea (d) L-sugars, L-amino acids.
(b) Acetic acid 52. The statement that is NOT correct is that
(c) Glycine (a) Aldose or ketose sugars in alkaline medium do not
(d) Aniline hydrochloride isomerise
45. In DNA, the complementary base are: (b) Carbohydrates are optically active
(a) Adenine and guanine, thymine and cytosine (c) Penta acetate of glucose does not react with
(b) Uracil and adenine, cytosine and guanine hydroxylamine.
(c) Adenine and thymine, guanine and cytosine (d) Lactose has glycosidic linkage between 𝐶 of
(d) Adenine and thymine, guanine and uracil. glucose and 𝐶 of galactose units.
46. The functional groups present in typical carbohydrates 53. Most common types of secondary structures of proteins
are : are :
(a) – 𝑂𝐻 𝑎𝑛𝑑 − 𝐶𝑂𝑂𝐻 (a) 𝛼-helix and 𝛽-helix structures
(b) – 𝐶𝐻𝑂 𝑎𝑛𝑑 − 𝐶𝑂𝑂𝐻 (b) 𝛼-helix and 𝛽-pleated sheet structures
(c) > 𝐶 = 𝑂 𝑎𝑛𝑑 −OH (c) Right and left hand twisted structures
(d) – 𝑂𝐻 𝑎𝑛𝑑 − 𝐶𝐻𝑂. (d) Globular and fibrous structures.
47. Fructose reduces Tollen’s reagent due to 54. Glucose on prolonged heating with HI gives
(a) Asymmetric carbon (a) n-Hexane
(b) Primary alcoholic group (b) 1-Hexane
(c) Secondary alcoholic group (c) Hexanoic acid
(d) Enolisation of fructose followed by conversion to (d) 6-iodohexanal.
aldehyde by base. 55. In nucleic acids, the nucleotides are joined together by
48. Which of the statements about “Denaturation” given (a) Phosphoester linkage
below are correct? (b) Phosphodisulphide linkage
a) Denaturation of proteins causes loss of secondary (c) Phosphodiester linkage
and tertiary structures of the protein. (d) Sulphodiester linkage.
b) Denaturation leads to the conversion of double 56. Glucose on reduction with Na/Hg and water gives
strand of DNA into single strand. (a) Sorbitol
c) Denaturation affects primary structure which gets (b) Saccharic acid
distorted. (c) Sorbitol + mannitol
(a) (2) and (3) (d) Hexane.

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57. The specific rotation of a freshly prepared solution of 67. In alkaline medium, alanine exists predominantly as/in
cane sugar changes with time and finally attains a ……….
constant value. This is called (a) Anion
(a) Inversion (b) Zwitter ion
(b) Mutarotation (c) Cation
(c) Isoelectric point (d) Covalent form.
(d) Optical rotation. 68. Tyrosine is a
58. How many atoms are there in pyranose ring? (a) Phenolic amino acid
(a) 3 (b) Sulphur containing amino acids
(b) 5 (c) Basic amino acid
(c) 6 (d) Heterocyclic amino acid.
(d) 7 69. One of the following is an essential amino acid
59. Chiral carbon atoms in glucose and fructose are (a) Cysteine
(a) 3 in each (b) Serine
(b) 3 in glucose and 4 in fructose (c) Tyrosine
(c) 4 in each (d) Isoleucine.
(d) 4 in glucose and 3 in fructose. 70. Which of the following statements is not correct about
60. Glucose contains in addition to aldehyde group DNA?
(a) One secondary OH and four primary OH groups (a) It has a double helix structure.
(b) One primary OH and four secondary OH groups (b) Its replication is called semiconservative mode of
(c) Two primary OH and three secondary OH groups replication.
(d) Three primary OH and two secondary OH groups. (c) The two DNA strands are exactly similar
61. Proteins find application as (d) It serves as the hereditary material.
(a) Antibodies 71. Which of the following has a single heterocyclic ring?
(b) Hormones (a) Adenine
(c) Enzymes (b) Guanine
(d) All the three. (c) Thymine
62. Which of the following is not the function of proteins? (d) None.
(a) Fight against infections 72. Complete hydrolysis of DNA/RNA produces
(b) Catalyse biological reactions in the body (a) Sugar
(c) Stimulation of physiological activities (b) Phosphoric acid
(d) Transfer of genetic character from parents to (c) Heterocyclic nitrogen base
children. (d) All the three.
63. The pH value of the solution in which a particular 73. Individual nucleotides in nucleic acids are linked by
amino acid does not migrate under the influence of an (a) Peptide linkage
electric filed is called the (b) Glycosidic linkage
(a) Eutectic point (c) Hydrogen bonds
(b) Yielding point (d) Phosphate group.
(c) Neutralizing point 74. Nucleotidide and nucleoside differs in
(d) Isoelectric point. (a) Phosphate group
64. In amino acids, the group which acts as acidic group is (b) Ribose sugar
(a) – 𝑁𝐻 (c) Nitrogen base
+ (d) All the three.
(b) − 𝑁 𝐻 75. Chargaff’s rule states that in an organism
(a) Amount of adenine (A) is equal to that of thymine
(c) −𝐶𝑂𝑂𝐻 (T) and amount of guanine (G) is equal to that of
(d) – 𝐶𝑂𝑂 cytosine (C).
65. Starting with three different amino acid molecules how (b) Amount of adenine (A) is equal to that of guanine
many different tripeptide molecules could be formed? (G) and the amount of thymine (T) is equal to that
(a) 3 (b) 6 (c) 9 (d) 12. of cytosine(C).
66. A nanopeptide contains……… peptide linkages.
(a) 10 (b) 8 (c) 9 (d) 18.

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(c) Amount of adenine (A) is equal to that of cytosine (c) Anthranilic acid
(C) and the amount of thymine (T) is equal to that (d) Alanine.
of guanine (G) 84. 𝛼-helix is also known as
(d) Amount of all bases are equal. (a) Sheet structure
76. The process of formation of RNA from DNA is known (b) 3.613 helix
as (c) 4.915 helix
(a) Transcription (d) Flat structure.
(b) Translation 85. The carboxyl terminus (i.e. C- terminus) of the peptide
(c) Phoshorylation structure is
(d) Replication. (a) On left hand side
77. The chemical change in DNA molecule leading to (b) On right hand side
synthesis of protein with altered amino acid sequence is (c) On both sides
known as (d) Not specific.
(a) Mutation 86. A chiral amino acid on reduction with 𝐿𝑖𝐴𝐼𝐻 loses its
(b) Replication chirality. It is
(c) Biotechnology (a) Glycine
(d) Translation. (b) Isoleucine
78. Monomer of nucleic acid is: (c) Valine
(a) Nucleotide (d) Serine.
(b) Nucleocide 87. In the give polypeptide :
(c) Amino acid Arg – Tyr – I1e – Met – Gly
(d) Carboxylic acid. N-terminus amino acid is
79. In nucleic acids the sequence is (a) Tyrosine
(a) Sugar –base –phosphate (b) Methionine
(b) Phosphate – base – sugar (c) Arginine
(c) Base –phosphate –sugar (d) Glycine.
(d) Base –sugar – phosphate. 88. Which base pair has more stability?
80. The double helical structure of DNA was proposed by (a) AT
(a) Meischer (b) CG
(b) Watson and Crick (c) AA
(c) Emil fisher (d) TT.
(d) Khorana. 89. In E. coil DNA the AT/GC ratio is 0.93. If the number
81. Which of the following amino acid has two – COOH of moles of adenine in its DNA sample are 465,000,
groups? what will be the no. of moles of guanine present
(a) Histidine (a) 465,000
(b) Aspartic acid (b) 5,64,000
(c) Lysine (c) Only 2
(d) Valine. (d) 5,00,000
82. Structures of alanine at pH = 2 and pH = 10 are 90. The reason for double helical structure of DNA is
respectively operation of
(a) Electrostatic attractions
(b) Van der Waal’s forces
(c) Dipole –dipole forces
(d) Hydrogen bonding
91. The presence or absence of hydroxyl group on which
carbon atom of sugar differentiates RNA from DNA
(a) 1st (b) 2nd (c) 3rd (d) 44th.
92. The number of possible different codons is:
(a) 48 (b) 16 (c) 64 (d) 32
83. Which of the following does not exist as a Zwitter ion?
(a) Glycine
(b) Sulphanilic acid
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Answer key

1. 3 2. 3 3. 3 4. 4 5. 4 6. b 7. 4 8. 3 9. 4 10. 3
11. 2 12. 2 13. 1 14. 3 15. 2 16. 3 17. 2 18. 4 19. 4 20. 4
21. 3 22. 3 23. 3 24. c 25. c 26. b 27. a 28. b 29. c 30. a
31. c 32. a 33. c 34. a 35. c 36. b 37. d 38. b 39. c 40. a
41. d 42. d 43. c 44. c 45. c 46. c 47. d 48. c 49. c 50. c
51. c 52. a 53. b 54. a 55. c 56. a 57. b 58. c 59. d 60. b
61. d 62. d 63. d 64. b 65. b 66. b 67. a 68. a 69. d 70. c
71. c 72. d 73. d 74. a 75. a 76. a 77. a 78. a 79. d 80. b
81. b 82. a 83. c 84. b 85. b 86. d 87. c 88. b 89. d 90. d
91. b 92. c

Mrs RavinderKaur Makkar, B.Sc. (Med), M.Sc (Chemistry), M.Phil (chemistry) B.Ed. Cell No. 9876289250 Page 7