Department of Pharmacology MCQs for 2nd MBBS

Sri Siddhartha Dental College, Tumkur

General Pharmacology
1 The following statements are TRUE regarding oral drug administration
a. Needs assistant
b. By passes the liver
c. Can be preferred in emergency
d. Low bioavailability
Ans d,
Pharmacology for dental and allied sciences by Padmaja udayakumar, 3 rd edition,p.6
Prepared by Dr Manjunath, Prof and Head of Pharmacology

2 The features of enteric coated tablets are all EXCEPT

a. Prevent gastric irritation
b. Avoid destruction by the stomach
c. Retard absorption
d. Acidic drugs are usually coated
Ans d,
Pharmacology for dental and allied sciences by Padmaja udayakumar, 3rd edition,p.7
Prepared by Dr Manjunath Prof and Head of Pharmacology

3 Transdermal patch has advantage EXCEPT

a. Prolonged action
b. Provide constant plasma level
c. Painful
d. Patient compliance
Ans c,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition.p.10
Prepared by Dr Manjunath Prof and Head of Pharmacology

4 The following route is used in case of emergency EXCEPT

a. Intravenous
b. Transdermal
c. Intramuscular
d. Sublingual
Ans b,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.7
Prepared by Dr Manjunath Prof and Head of Pharmacology
5 First pass metabolism is
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

a. Metabolism after reaching plasma

b. Metabolism taking place in liver
c. Metabolism when given by any route
d. Metabolism which takes place after oral route
Ans b,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.16
Prepared by Dr Manjunath Prof and Head of Pharmacology

6 All acidic drugs bind to

a. Albumin
b. Globulin
c. Alpha 1 acid glycoprotein
d. Myoglobin
Ans a,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.18
Prepared by Dr Manjunath Prof and Head of Pharmacology

7 Biotransformation of drugs MAINLY takes place in

a. Lungs
b. Kidney
c. Liver
d. Blood
Ans c,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.20
Prepared by Dr Manjunath Prof and Head of Pharmacology

8 The drug which undergoes zero order kinetics is

a. Alcohol
b. Paracetamol
c. Morphine
d. Diazepam
Ans a,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.23
Prepared by Dr Manjunath Prof and Head of Pharmacology

9 The following statements are TRUE regarding plasma half life EXCEPT
a. It takes 4-5 half life for elimination
b. It takes 4-5 half life for reaching steady state
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

c. Half life does not change in First order kinetics

d. Half life remains same in renal disease
Ans d,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.23
Prepared by Dr Manjunath Prof and Head of Pharmacology

10 Agonist is one which

a. Binds to receptor but no response
b. Binds to receptor and produce response
c. Do not bind to receptor
d. Binds but produces minimal response
Ans b,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.27
Prepared by Dr Manjunath Prof and Head of Pharmacology

11 The drug of first choice in anaphylactic shock

a. Adrenaline
b. Noradrenaline
c. Dopamine
d. Isoprenaline
Ans a,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.39
Prepared by Dr Manjunath Prof and Head of Pharmacology

12 Steven Johnson syndrome is ------type of hypersensitivity reaction

a. Type I
b. Type II
c. Type III
d. Type IV
Ans c,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.39
Prepared by Dr Manjunath Prof and Head of Pharmacology

Autonomic nervous system

13 Which among these is an cholinomimetic alkaloid
a. Acetylcholine
b. Pilocarpine
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

c. Neostigmine
d. Succinylcholine
Ans b,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.53
Prepared by Dr Manjunath Prof and Head of Pharmacology

14 The cholinergic agent which is used as sialogogue is

a. Cevemiline
b. Methacholine
c. Carbachol
d. Bethenechol
Ans a,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.54
Prepared by Dr Manjunath Prof and Head of Pharmacology

15 The anticholinesterase preferred in treatment of myasthenia gravis is

a. Physostigmine
b. Neostigmine
c. Edrophonium
d. Glucocorticoid
Ans b,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.57
Prepared by Dr Manjunath Prof and Head of Pharmacology

16 The anticholinesterase preferred in glaucoma is

a. Physostigmine
b. Neostigmine
c. Edrophonium
d. Glucocorticoid
Ans a,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.55
Prepared by Dr Manjunath Prof and Head of Pharmacology
17 The antidote for organophosphorous poisoning is
a. Atropine
b. Neostigmine
c. Physostimine
d. Ecothiophate
Ans a,
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.59
Prepared by Dr Manjunath Prof and Head of Pharmacology

18 Oximes are specifically used in which poisoning

a. Belladonna poisoning
b. Atropine poisoning
c. Carbamate poisoning
d. Organophosporous poisoning
Ans d,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.60
Prepared by Dr Manjunath Prof and Head of Pharmacology

19 The drug of choice in atropine poisoning is

a. Physostigmine
b. Neostigmine
c. Edrophonium
d. Glucocorticoid
Ans a,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.56
Prepared by Dr Manjunath Prof and Head of Pharmacology

20 The following effects are seen with atropine EXCEPT

a. Dry mouth
b. Constipation
c. Urinary retention
d. Bradycardia
Ans d,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.62
Prepared by Dr Manjunath Prof and Head of Pharmacology

21 The atropine substitute used in bronchial asthma is

a. Ipratopium bromide
b. Hydrocortisone
c. Salbutamol
d. Theophylline
Ans a,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.63
Prepared by Dr Manjunath Prof and Head of Pharmacology
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

22 The atropine substitute used in pre-anesthetic medication is

a. Ipratopium
b. Glycopyrrolate
c. Dicyclomine
d. Scopolamine
Ans b,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.63
Prepared by Dr Manjunath Prof and Head of Pharmacology

23 Adrenaline reduces bleeding due to its action on

a. Alpha 1
b. Alpha 2
c. Beta 1
d. Beta 2
Ans a,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.76
Prepared by Dr Manjunath Prof and Head of Pharmacology

24 Adrenaline is used in which type of shock

a. Cardiogenic shock
b. Septic shock
c. Neurogenic shock
d. Anaphylactic shock
Ans d,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.76
Prepared by Dr Manjunath Prof and Head of Pharmacology

25 Route of administration of adrenaline in anaphylactic shock

a. Oral
b. Intramuscular
c. Rectal
d. Sublingual
Ans b,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.76
Prepared by Dr Manjunath Prof and Head of Pharmacology

26 Dopamine is used in shock because

 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

a. It improves renal blood flow

b. It improves cerebral blood flow
c. It reduces cardiac work
d. It reduces blood pressure
Ans a,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.77
Prepared by Dr Manjunath Prof and Head of Pharmacology

27 Nasal decongestants produces hypertension on long use due to its effects on

a. Alpha 1
b. Beta 1
c. Beta 2
d. D1
Ans a,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.80
Prepared by Dr Manjunath Prof and Head of Pharmacology

28 Which of the following is a selective alpha 1 blocker

a. Propranolol
b. Lignocaine
c. Prazosin
d. Pilocarpine
Ans c,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.83
Prepared by Dr Manjunath Prof and Head of Pharmacology

29 Which of the following is cardio selective blocker

a. Atenelol
b. Propranolol
c. Prazosin
d. Timolol
Ans a,
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.86
Prepared by Dr Manjunath Prof and Head of Pharmacology
30 The ultra short acting beta blocker is
a. Propronolol
b. Atenelol
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

c. Esmolol
d. Labetalol
Ans c,
Page no. 106, Essentials of Pharmacology for dentistry by KD Tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

Peripheral nervous system

31 The depolarising blocker used for intubation is

a. Pancuronium
b. Diazepam
c. Dantrolene
d. Succinylcholine
Ans c.
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.68
Prepared by Dr Manjunath Prof and Head of Pharmacology

32 The shortest acting competitive neuromuscular blocker is

a. Mivacurium
b. Diazepam
c. Dantrolene
d. Succinylcholine
Ans a.
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.66
Prepared by Dr Manjunath Prof and Head of Pharmacology
33 Hoffmann elimination is undergone by
a. Atracurium
b. Pancuronium
c. Succinylcholine
d. Mivacurium
Ans a.
Page no. 134, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

34 The drug of choice for malignant hyperthermia is

a. Halothane
b. Succinylcholine
c. Diazepam
d. Dantrolene
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

Ans d.
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.69
Prepared by Dr Manjunath Prof and Head of Pharmacology

35 The local anaesthetic used as both surface and injectable

a. Lignocaine
b. Oxethazine
c. Cocaine
d. Procaine
Ans a.
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.145
Prepared by Dr Manjunath Prof and Head of Pharmacology

36 The mechanism of action of lignocaine is

a. Calcium channel blockade
b. Activates GABA channel
c. Sodium channel blocker
d. Potassium channel opener
Ans c.
Pharmacology for dental and allied sciences by padmaja udayakumar, 3rd edition,p.146
Prepared by Dr Manjunath Prof and Head of Pharmacology

37 The advantages of combining adrenaline with lignocaine are all EXCEPT

a. Reduces systemic toxicity
b. Prolongs action
c. Reduces blood supply
d. Fastens healing
Ans d.
Page no. 360, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

38 The cardiac use of lignocaine is

a. Hypertension
b. Cardiac arrhythmia
c. Heart failure
d. Angina pectoris
Ans b.
Page no. 363, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

Prepared by Dr Manjunath Prof and Head of Pharmacology

39 Eutectic mixture is produced by combining lignocaine with

a. Cocaine
b. Prilocaine
c. Bupivacaine
d. Tetracaine
Ans b.
Page no. 363, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

40 The cardiotoxic local anaesthetic is

a. Cocaine
b. Prilocaine
c. Bupivacaine
d. Tetracaine
Ans c.
Page no. 364, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

41 The earliest sensation to be lost following injection of lignocaine is

a. Pain
b. Temp
c. Touch
d. Pressure
Ans a.
Page no. 360, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

42 The earliest sensation to be lost when applied topically into oral cavity is
a. Bitter
b. Sweet
c. Sour
d. Salt
Ans a.
Page no. 360, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

43 The only anesthetic effective in acidic pH is

a. Lignocaine
b. Oxethazine
c. Cocaine
d. Procaine
Ans b.
Page no. 364, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

Central nervous system

44 The drug which produces dissociative anesthesia is

a. Halothane
b. Thiopentone
c. Ketamine
d. Diazepam
Ans c.
Page no. 129, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology
45 The drug which is used as carrier agent in anaesthesia is
a. Halothane
b. Thiopentone
c. Ketamine
d. Nitrous oxide
Ans d.
Page no. 126, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

46 Which of the following drug is used as intravenous inducing agent

a. Thiopentone
b. Diazepam
c. Ketamine
d. Fentanyl
Ans a.
Page no. 127, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

47 The drug which is used as antagonist in benzodiazepine poisoning is

 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

a. Naloxone
b. Disulifiram
c. Flumazenil
d. Methadone
Ans c.
Page no. 145, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

48 The only benzodiazepines absorbed effectively by intramuscular route is

a. Diazepam
b. Lorazepam
c. Nitrazepam
d. Chlordiazepoxide
Ans b.
Page no. 143, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

49 The treatment of choice in methyl alcohol poisoning is

a. Methanol
b. Ethanol
c. Propylene glycol
d. Disulfiram
Ans b.
Page no. 147, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

50 The drug of choice in alcohol de-addiction is

a. Dislfuram
b. Naloxone
c. Flumazenil
d. Acetylcysteine
Ans a.
Page no. 147, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

51 The drug of choice in status epilepticus is

a. Diazepam
b. Phenytoin
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

c. Phenobarbitone
d. Ethosuximide
Ans a.
Page no. 154, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

52 The following anti epileptic drugs act by sodium channel blockade EXCEPT
a. Phenytoin
b. Carbamazepine
c. Valproate
d. Diazepam
Ans d.
Page no. 149, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

53 The antiepileptic known to produce cleft lip and palate as teratogenic effect is
a. Phenytoin
b. Carbamazepine
c. Valproate
d. Diazepam
Ans a.
Page no. 150, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

54 The antiepileptic drug used in trigeminal neuralgias is

a. Carbamazepine
b. Diazepam
c. Ethosuximide
d. Phenobarbitone
Ans a.
Page no. 151, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

55 The broad spectrum antiepileptic is

a. Phenytoin
b. Carbamazepine
c. Valproate
d. Diazepam
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

Ans c.
Page no. 151, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

56 Drug of choice for febrile convulsions

a. Phenytoin
b. Carbamazepine
c. Valproate
d. Diazepam
Ans d.
Page no. 154, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

57 The drug used for opioid de-addiction is

a. Naloxone
b. Naltrexone
c. Methadone
d. Tramadol
Ans c.
Page no. 348, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

58 The antidote in morphine poisoning is

a. Acetyl cysteine
b. Desferrioxamine
c. Flumazenil
d. Naloxone
Ans d.
Page no. 355, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

59 Tramadol is an
a. Beta blocker
b. Opioid analgesic
c. Local anesthetic
d. Inducing agent
Ans b.
Page no. 350, Essentials of Pharmacology for dentistry by KD tripathi, 3rd edition,
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

Prepared by Dr Manjunath Prof and Head of Pharmacology

60 Opioid analgesic which should not be used in myocardial infarction is

a. Morphine
b. Pethidine
c. Pentazocine
d. Tramadol
Ans c.
Page no. 354, Essentials of Pharmacology for dentistry by KD tripathi, 3 rd edition,
Prepared by Dr Manjunath Prof and Head of Pharmacology

Antihistamines, Cough and Bronchial asthma

61 Which of the following is NOT a first generation antihistamine?

a. Promethazine
b. Diphenhydramine
c. Chlorphenaramine maleate
d. Azelastine
Correct answer –d
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3th ed. p.113.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

62 Which of the following drugs is used in pre-anaesthetic medication?

a. Promethazine
b. Levocetrizine
c. Desloratidine
d. Ebastine
Correct answer – a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3th ed. p.115
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

63 Which among the following drugs do not cause sedation?

a. Chlorphenaramine
b. Dimenhydrinate
c. Promethazine
d. Levocetirizine
Correct answer is –d
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3th ed. p.113.
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

64 Which of the following is a first generation anti-histaminic agent?

a. Cetirizine
b. Cyclizine
c. Loratidine
d. Fexofenadine
Correct answer: b
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.102.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.
65 The non sedative (2nd generation) antihistamines are all EXCEPT:
a. Desloratidine
b. Fexofenadine
c. Levocetirizine
d. Cinnarizine
Correct answer: d
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. P.102.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

66 Antihistaminic drug used in motion sickness is:

a. Cetirizine
b. Fexofenadine
c. Promethazine
d. Azelastine
Correct answer: c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.104.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

67 Which of the following H1 blocker has anti-cholinergic activity?

a. Cetirizine
b. Chlorpheniramine
c. Fexofenadine
d. Astemizole
Correct answer: b
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.103.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

68 Inflammation in the bronchial airways can be reduced by:

 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

a. Beclomethasone
b. Theophylline
c. Salbutamol
d. Ipratropium
Correct answer: a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.297.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

69 The following drug is NOT useful during acute attack of bronchial asthma:
a. Salbutamol
b. Hydrocortisone
c. Cromolyn sodium
d. Theophylline
Correct answer: c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.298.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

70 Ipratropium bromide used in bronchial asthma, is:

a. Beta-2 agonist
b. Methylxanthine
c. Anticholinergic
d. Mast cell stabilizer
Correct answer: c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.293.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

71 Centrally acting cough suppressant is :

a. Bromhexine
b. Acetyl cysteine
c. Codeine
d. Ambroxol
Correct answer: c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.291.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

72 Which of the following is a Long acting β2 agonist:

a. Salbutamol
b. Terbutaline
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

c. Salmeterol
d. Theophylline
Correct answer: c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.294.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

73 Most common side effect of inhalational steroids is:

a. Cushing’s syndrome
b. Decreased ACTH
c. Systemic complications
d. Oropharyngeal candidiasis
Correct answer: d
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.298.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

74 Which of the following drug is contraindicated in bronchial asthma:

a. Propranolol
b. Ipratropium bromide
c. Theophylline
d. Ketotifen
Correct answer: a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.95.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

75 Most common dose related side effects of salbutamol is:

a. Nervousness
b. Hypertension
c. Restlessness
d. Tremors
Correct answer: d
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.293.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

76 Mechanism of action of montelukast is:

a. Leukotriene antagonist
b. Alpha receptor blocker
c. Beta receptor blocker
d. Prostaglandin anatgonist
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

Correct answer: a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.296.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

77 Inhalational steroids are all EXCEPT:

a. Betamethasone
b. Beclomethazone
c. Budesonide
d. Fluticazone
Correct answer: a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.298.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

78 Which of the following is NOT a bronchodilator?

a. Beta 2 agonists
b. Methylxanthines
c. Steroids
d. Anticholinergics
Correct answer: c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.293.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

Cardiovascular system
79 The drug which is useful in hypertension associated with Benign Prostatic Hyperplasia?
a. Prazosin
b. Nifidepine
c. Atenolol
d. Esmolol
Correct answer –
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3h ed. p.186.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

80 The drug with low therapeutic index is?

a. Nifidepine
b. Captopril
c. Digoxin
d. Metoprolol
Correct answer- c
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.199.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC
81 The mechanism of action of Nitrates is
a. Release Nirtic oxide
b. Potassium channel opener
c. Beta receptors blockade
d. ACE inhibition
Correct answer – a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.192.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

82 Which among these is a potassium channel opener?

a. Nicorandil
b. Diltiazem
c. Esmolol
d. Captopril
Correct answer – a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.194.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

83 The antihypertensive safe in pregnancy is

a. Alpha methyldopa
b. Paptopril
c. Telmisartan
d. Lisinopril
Correct answer – a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.187.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

84 The antihypertensive of choice in hypertensive emergency is?

a. Atenolol
b. Prazosin
c. Sodium nitroprusside
d. Captopril
Correct answer – c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.189
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

Diuretics
85 Which of the following drugs are high ceiling diuretics
a. Furosemide
b. Mannitol
c. Spironolactone
d. Hydrochlorothiazide
Correct answer is – d
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.211.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

86 All of the following are the indications for high ceiling diuretics EXCEPT
a. Cirrhosis of liver
b. Pulmonary edema
c. Heart failure
d. Hypokalemia
Correct answer- d
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.209
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

87 Which of the following drugs is aldosterone antagonist?

a. Furosemide
b. Hydrochlorothiazide
c. Spironolactone
d. Bumatanide
Correct answer – c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.211.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

88 Mannitol belongs to which of the following Diuretics?

a. Loop diuretics
b. Thiazides
c. Osmotic diuretics
d. Potassium sparing diuretics
Correct answer – c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.211.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC
89 Adverse effects of loop diuretics are all EXCEPT
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

a. Hyperkalemia
b. Hypomagnesemia
c. Hyperuricaemia
d. Hypocalcemia
Correct answer –a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.211.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

90 Which diuretics class of drugs is useful in treatment of Glaucoma?

a. Carbonic anhydrase inhibitors
b. Loop diuretics
c. Potassium sparing diuretics
d. Thiazides
Correct answer – a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.216
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

91 Sodium -Chloride symport in kidney is inhibited by

a. Thiazide diuretics
b. Potassium sparing diuretics
c. Carbonic anhydrase Inhibitors
d. Osmotic diuretics
Correct answer –a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.211.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

92 Na-K-2Cl co-transport in kidney is inhibited by?

a. Potassium sparing diuretics
b. Loop diuretics
c. Osmotic diuretics
d. Thiazides
Correct answer – b
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.211.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

Endocrines
93 Which of the following drugs is useful in Insulin resistance?
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

a. Acarbose
b. Glibenclamide
c. Pioglitazone
d. Glimipiride
Correct answer –c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.231
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

94 The antidiabetic drug which does not cause hypoglycaemia is?

a. Metformin
b. Pioglitazone
c. Gliclazide
d. Glimipiride
Correct ans- a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.230.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

95 Which of the following is long acting Insulin?

a. Insulin Glargine
b. Insulin aspart
c. Insulin lispro
d. Insulin glulysine
Correct answer – a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.226
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

96 Steroids are contraindicated in all of the following conditions EXCEPT

a. Peptic ulcer
b. Osteoporosis
c. Diabetes mellitus
d. Rheumatoid arthritis
Correct answer- d
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.238.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC
97 Which of the following steroid preparations is long acting?
a. Dexamethasone
b. Hydrocortisone
c. Prednisolone
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

d. Methyl prednisolone
Correct answer- a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.237
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

98 Thyroid release inhibitor is

a. Methimazole
b. Lugol’s iodine
c. Radioactive Iodine
d. Propylthiouracil
Correct answer –b
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.253
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

99 Antithyroid drug safe in pregnancy is

a. Propylthiouracil
b. Radioactive iodine
c. Lugol’s iodine
d. Levothyroxine
Correct answer – a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 3rd ed. p.253.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

100 All of the following are adverse drug reactions of steroids Except
a. Glaucoma
b. Hypertension
c. Osteoporosis
d. Osteoarthritis
Correct answer –d
Ref-Dr. Padmaja, pharmacology for dental and allied health sciences 3 rd edn p 382
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

Blood

101 The antidote for heparin induced bleeding is

a. Enoxaparin
b. Protamine sulphate
c. Vitamin K
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

d. Aspirin
Correct answer – b
Ref- Padmaja, pharmacology for dental and allied health sciences 3rd edition p 253
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

102 All of the following are low molecular weight Heparins EXCEPT
a. Enoxaparin
b. Reviparin
c. Dalteparin
d. Lepirudin
Correct answer – d
Ref- Padmaja, pharmacology for dental and allied health sciences 3rd edition p 251
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

103 Which of the following is not a styptic?

a. Fibrin
b. Gelatin foam
c. Adrenaline
d. Sodium edetate
Correct answer –d
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.268
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

104 The anticoagulant safe in Pregnancy is

a. Heparin
b. Enoxaparin
c. Dalteparin
d. Warfarin
Correct answer – a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.273.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC
105 Which of the following is not a parenteral iron preparation?
a. Iron dextran
b. Iron Sorbitol citric acid
c. Ferrous sucrose
d. Ferrous Fumorate
Correct answer – d
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.263.
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

106 Antidote for acute iron poisoning is

a. Desferrioxamine
b. EDTA
c. BAL
d. D.penicillamine
Correct answer – a
Ref: Padmaja udaykumar, editor. Pharmacology for dental and allied health sciences. 3 th
ed. p.424
Prepared by: Dr. Naveen Kumar, Professor, Dept of Pharmacology, SSMC

Chemotherapy, chelating agents and dental pharmacology

107 Superinfection is common in:
a. Narrow spectrum antibiotics
b. Broad spectrum antibiotics
c. Extended spectrum antibiotics
d. Nutritional deficiency
Correct answer: b
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.369.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

108 Which of the following is a broad spectrum antibiotic?

a. Erythromycin
b. Streptomycin
c. Tetracycline
d. Dapsone
Correct answer: c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.405.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.
109 True statement about penicillin G is:
a. It is administered orally
b. It has a wide spectrum
c. Hypersensitivity reactions
d. Long acting
Correct answer: c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.395.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

110 A potent inhibitor of beta-lactamase is:

 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

a. Carbenicillin
b. Clavulanic acid
c. Cefamandole
d. Cefixicime
Correct answer: b
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. P.398.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

111 Amoxycillin is better than ampicillin due to:

a. Better bioavailability
b. Incomplete absorption
c. Incidence of diarrhea is higher
d. More active against Shigella
Correct answer: a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.397.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

112 Mechanism of action of beta lactam antibiotics is to inhibit:

a. Protein synthesis
b. Cell wall synthesis
c. RNA synthesis
d. DNA gyrase
Correct answer: b
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.390.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

113 All of the following are beta-lactamase inhibitors EXCEPT:

a. Clavulanic acid
b. Sulbactum
c. Tazobactum
d. Aztreonam
Correct answer: d
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.398.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

114 Ototoxicity and nephrotoxicity is seen with:

a. Penicillin
b. Aminoglycosides
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

c. Macrolides
d. Rifampicin
Correct answer: b
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.414.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

115 Mechanism of action of fluoroquinolones is:

a. Inhibits cell wall synthesis
b. Inhibits DNA gyrase
c. Inhibits protein synthesis
d. Inhibits DHFRase
Correct answer: b
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.383.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

116 Gray baby syndrome is caused by:

a. Chlorpromazine
b. Chloramphenicol
c. Phenytoin
d. Gentamicin
Correct answer: b
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.412.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

117 Drug of choice for Syphilis is:

a. Penicillin
b. Rifampicin
c. Tetracycline
d. Erythromycin
Correct answer: a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.394.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

118 All are first line anti-tubercular drugs EXCEPT:

a. Isoniazid
b. Cycloserine
c. Pyrazinamide
d. Ethambutol
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

Correct answer: b
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.428.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

119 Ethambutol causes:

a. Optic neuritis
b. Deafness
c. Red urine
d. Peripheral neuritis
Correct answer: a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.431.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

120 Bacteriostatic drug in ATT is:

a. Isoniazid
b. Rifampicin
c. Ethambutol
d. Streptomycin
Correct answer: c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.430.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

121 Antitubercular drug causing orange colored urine is:

a. Streptomycin
b. Isoniazid
c. Ethambutol
d. Rifampicin
Correct answer: d
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.430.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

122 Topically used antifungal agent is:

a. Ketoconazole
b. Clotrimazole
c. Amphotericin B
d. Itraconazole
Correct answer: b
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.438.
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

123 Which of the following is a broad spectrum systemic antifungal agent?

a. Econazole
b. Miconazole
c. Ketoconazole
d. Clotrimazole
Correct answer: c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.442.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

124 Drug of choice for herpes simplex virus infection is:

a. Acyclovir
b. Zidovudine
c. Indinavir
d. Ribavarin
Correct answer: a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.445.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

125 Which of the following is a nucleoside reverse transcriptase inhibitor?

a. Indinavir
b. Ritonavir
c. Nelfinavir
d. Zidovudine
Correct answer: d
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.447.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

126 Which of the following is most common side effect of zidovudine?

a. Anemia
b. Peripheral neuropathy
c. Lactic acidosis
d. Vomiting
Correct answer: a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.447.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.
 Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur

127 Round worm infestation is best treated with:

a. Metronidazole
b. Ivermectin
c. Albendazole
d. Praziquantel
Correct answer: c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.464.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

128 Cyclophosphamide can cause:

a. Hemorrhagic cystitis
b. Cardiomyopathy
c. Neuropathy
d. Convulsions
Correct answer: a
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.313.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

129 Folinic acid counteracts the toxicity of:

a. Doxorubicin
b. Methotrexate
c. Cyclophosphamide
d. Fluorouracil
Correct answer: b
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.308, 313.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.

130 Which of the following is an inhibitor of dihydrofolate reductase?

a. Phenytoin
b. Alcohol
c. Methotrexate
d. Vincristine
Correct answer: c
Ref: KD Tripathi, editor. Essentials of Pharmacology for dentistry. 2th ed. p.308.
Prepared by: Dr. Nandini T, Associate professor, Dept of Pharmacology, SSMC.
Department of Pharmacology MCQs for 2nd MBBS
Sri Siddhartha Dental College, Tumkur