Biostat Finals Revised

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1) The following data were obtained in a study of the Which of the following is an appropriate null hypothesis?

relationship between the weight and chest size of


infants at birth: m = 64.82
Weight (kg): 2.75 2.15 4.41 5.52 3.21 4.32 2.31 m ¹ 64.82
4.30 3.71 m = 65.42
Chest Size 29.5 26.3 32.2 36.5 27.2 27.7 28.3 m ¹ 65.42
30.3 28.7
(cm) 7). A pill is supposed to contain 25.4 milligrams of
phenobarbital. A random sample of 30 pills yield a mean of
Determine the equation of the regression line. 19.7 milligrams and a standard deviation of 0.95 milligrams.
What test is appropriate for this?
Y=A + BX
Y = 21.7 + 2.2X z-test
Y=2.2+ 21.7X t-test
no regression equation χ2
f-test
2). The heights of adults in a certain town has a mean of
65.42 inches with a standard deviation of 2.32 inches. A 8). A random variable is known to be normally distributed
random sample of 144 adults living in the slum district is with mean 100 and standard deviation 10. The probability
found to have a mean height of 64.82 inches. Does this that an observed value of this random variable is less than
indicate that the residents of slums are significantly 90 or greater than 110 is approximately
retarded in growth at a 0.05 level of significance?
The appropriate test is a 0.15
0.32
one-tailed Z-test 0.68
one-tailed t-test 0.84
two-tailed Z-test 0.95
two-tailed t-test
9). The heights of adults in a certain town has a mean of
3). A geneticist is interested in the proportion of males and 65.42 inches with a standard deviation of 2.32 inches. A
females in a population that have a certain minor blood random sample of 144 adults living in the slum district is
disorder. In a random sample of 100 males, 31 are found to found to have a mean height of 64.82 inches. Does this
be afflicted whereas only 24 of 100 females tested appear indicate that the residents of slums are significantly
to have the disorder. retarded in growth at a 0.05 level of significance?
What test statistic is appropriate for this problem? Which of the following is an appropriate alternative
hypothesis?
t-test for two sample means
z-test for single proportion m ¹64.82
z-test for two sample means m > 65.42
z-test for two proportions
m ¹ 65.42
m < 65.42
4). Which of the following statements is TRUE?
10). A Municipal Health Officer and his staff aim to cover
If the level of significance is 5%, then the critical region of a
80% of the target population for their Expanded Program for
two-tailed test has an area of 2.5%.
Immunization (EPI). After implementing the program, they
If r=0, then X and Y are not linearly related.
surveyed 1500 children and found that 1000 of them were
ANOVA is a test concerning several variances.
immunized. Did the MHO and his staff attain his goal? Test
Rejecting Ho in a chi-square test of independence means
at a 0.05 level of significance.
that the row and column classifications are independent.
What test – statistic will you use to answer the question?
5). A pill is supposed to contain 25.4 milligrams of
two-tailed z-test
phenobarbital. A random sample of 30 pills yield a mean of
one-tailed z-test
19.7 milligrams and a standard deviation of 0.95 milligrams.
f-test
What null hypothesis is appropriate for the problem?
Chi-Square test
H0: μ1 = μ2
H0: μ1 ≠ μ2
H0: μ1 = 25.4
H0: μ1 ≠ 25.4

6). The heights of adults in a certain town has a mean of


65.42 inches with a standard deviation of 2.32 inches. A
random sample of 144 adults living in the slum district is
11). A study looking at the relationship between salt intake
found to have a mean height of 64.82 inches. Does this
to the blood pressure of infants was recently conducted.
indicate that the residents of slums are significantly
retarded in growth at a 0.05 level of significance?
The study involved 15 infants with a low salt diet and 20 The average time of 18 min. does not help the patients
infants with a high salt diet. The results are: recover from cough.
High Salt Low Salt
Diet Diet
16). The level of serum creatinine in the blood is considered
Mean Systolic Blood Pressure 90.8 87.2
a good indicator of the presence or absence of kidney
Std Deviation Systolic Blood 10.3 9.2 disease. Normal persons generally have low concentrations
Pressure of serum creatinine while diseased persons have high
N 20 15 concentrations. Suppose we desire to look at the relation
between analgesic abuse and kidney disorder. In particular,
suppose we look at 15 persons working in a factory who are
What can we conclude at the .05 level of significance about known to be "analgesic abusers" (i.e., they take more than
blood pressure and the level of salt in the diet? The 10 pills per day) and we measure their creatinine levels.
appropriate test statistic is The creatinine levels are:
one-tailed t-test
two-tailed t-test .9 1.1 1.6 2.0 .8
one-tailed z-test
two-tailed z-test .7 1.4 1.2 1.5 .8

1.0 1.1 1.4 2.2 1.4


12).Two lots of rats were used in testing the effectiveness
of a new serum in combating a certain disease. Both were
If we assume that creatinine levels for normal
inoculated with the causative organism but only one lot was
persons are normally distributed with a mean of 1.0
previously given with preventive serum. The results are
and a standard deviation of .25, at the .01 level of
given below. What is the best statistical test to check the
significance what can we conclude?
effectivity of the new serum.
Serum No
Serum What appropriate test-statistic should be used to address
Recovered 18 4 the problem?
Died 4 18
one-tailed t-test for single mean
Point Biserial two-tailed t-test for single mean
Phi-coefficient one-tailed z-test
Kendall?s coefficient two-tailed z-test
Pearson?s r coefficient
When the alternative hypothesis is X>Xo and the computed
13). The LD50 (lethal dose 50), ED50(effective dose 50) value of the test statistics is greater than the critical value
and ID50(infective dose 50) are example of then the

Mean 17). alternative hypothesis is accepted


Mode alternative hypothesis is rejected
Median null hypothesis is accepted
Mean Deviation result is always accurate

14). When the value of correlation coefficient is1, then it 18). Kendall’s test statistics is concerned with the
means that
test for difference between two parameters
there is a perfect relation between the two parameters. test for independence
there is a weak negative relation between the two test for the agreement of two or more opinions
parameters test for fitting a specific curve
there is a strong direct relation between the two parameters
there is no relation between the two parameters 19). A subject of recent research in obstetrics is the medical
management of women who go into labor prematurely,
15). A drug company alleges that the average time for a which will be defined as labor occurring between 20 and 36
cough syrup to take effect is 15 min., with a standard weeks of pregnancy. Premature labor is undesirable
deviation of 3 min. In a random sample of 49 patients, the because infants born prematurely have a higher rate of
average time was 18 min. The correct null hypothesis is infant mortality and morbidity.

The random sample of 49 patients is not enough to test the Terbutaline is a drug that is effective in arresting labor
effectivity of the cough syrup. and prolonging the duration of the pregnancy beyond
There is no difference between the sample and population 36 weeks. However, it sometimes has undesirable
average time (in min.) for a cough syrup to take effect. cardiovascular and metabolic side effects such as
The drug company is not capable of making cough tremors and hyperglycemia, which limits its use for
syrup with a standard deviation of 3 min. only. some women.
Another possibility is to give terbutaline in
combination with another drug (metoprolol) which
would neutralize these side effects. However,
before using the combination therapy we want to
be sure it is as effective as terbutaline alone in
prolonging labor.

Suppose that a clinical trial is carried out


comparing the effectiveness of the two therapies
where the outcome is whether the pregnancy lasts
beyond 36 weeks. We find that in 200 patients
treated with terbutaline alone, 130 have a
pregnancy lasting more than 36 weeks while in 200
patients treated with terbutaline and metoprolol,
120 have a pregnancy lasting more than 36 weeks.

Test the hypothesis that the combination of


terbutaline and metoprolol is as effective as
terbutaline alone at the .05 level of significance.

The appropriate type of test is

independent t-test for 2 means assuming equal variances


independent t-test for 2 means assuming variances are not
equal
one-tailed z-test for two proportions
two-tailed z-test for two proportions

20). For Analysis of Variance (ANOVA), the statistical test is

z test
x2 test
t test
f test

All the following test statistics make use of ranking, with the
exception of

21). Chi-square
Kendall?s coefficient of concordance
Spearman rho coefficient of correlation
Wilcoxon?s test

22).Which of the following is not an application of chi-


square test?

Test for association between two categorical parameters


Test for multiple column proportions.
Test for the mean difference between two groups
Test for independence

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