Universidad del Valle de México.

Technical English.

Gaby Moreyra Muñoz.

Paola Elizabeth González Martínez.

Connective tissue disorders

10/11/23
Disorder Symptoms Causes Risk factors Diagnosis Treatment
Churg-Strauss S High levels of Inflammation Genetic Blood tests. Drugs as
eosinophils. of the blood determinants. Imaging studios. glucocorticoids.
Rhinosinusitis. vessels. Allergic Biopsy. Intravenous immune
Fever and agents: globulins (IVIG).
fatigue. Asthma, is Novel biologic agents.
Loss of apetite. often
Muscle and joint associated
pain. with a history
Peripheral of asthma.
neuropathy. Genetic
factors.
Dermatomyositis Skin rash: violet Inflammatory Gender: Medical history Medication such as
or red that myopathy Women. and physical steroids,
appears on the that involves Adults: ages examination. immunosupressants
face, eyelids, of 40 and 60. Blood test. and antimalarials.
knuckles, chest Genetics. Electromyography. Physical therapy.
and back. Skin biopsy.
Affects the Imaging studies.
muscles. Lung function test.
Ehlers-Danlos S Hyper-elastic There is an History family Is based on the Multidisciplinary car
skin. abnormality with this sign and involving specialist.
Hypermobility. with the condition. symptoms. Physical therapy.
Bruises. genes that DNA test to find Drugs for the pain.
Dislocations. encodes the the mutation in
Gastrointestinal collagen. genes that encode
problems: Genetic collagen.
constipation or mutations.
irritable bowel Autosomal
syndrome can dominant
occur. inheritance.
Cardiovascular Genetic
issues; fragile variability.
blood vessels
Lupus Arthritis. The immune Gender- Blood and urine Nonsteroidal anti-
Fevers. system Women. test. inflammatory drugs.
Fatigue. attacks its Clinical signs and Corticosteroids.
Butterfly rash. own tissue. Age: between symptoms. Antimalarial.
Hair loss. This causes 15 and 45. Medical history. Immunosuppressive
Swollen glands. tissue Skin or kidney agents/chemotherapy.
Headaches. damage as Race: African, biopsy
Depression, inflammation American,
confusion or of the skin Asian.
seizures. and organs.
History of
Sunlight, autoimmune
infections, disorders.
medications
 affects the
DNA.
Marfan Ectopia lentis Is for Based on the Depends on the area
that complicate abnormalitie; presence of of the body that is
into glaucoma mutation in skeletal and/or affected:
and cataracts. the genes ocular Surgical for the aorta
Arachnodactyly. that encodes abnormalities. problems.
Disproportionate fibrillin 1 FBNI sequencing. Scoliosis braces.
tall sture. Familiar history. B-blockers and
Chest Ghent criteria. angiotensin receptor
deformities. blockers.
Aortic root
aneurysm.
Osteogenesis Bone Fragility. Defect or Genetic Clinical diagnosis, Physical therapy.
Imperfecta Bone deficiency in factors; is a check the Medications to
deformities. the family history presence of bone strength bones.
Hyperlaxity. production of of the fragility in Bone care, such as a
Muscle type I condition. childhood. cast or brace.
weakness. collagen. Surgery to correct
Short stature. Parenteral bones.
Sensitive skin. Age: Older Walkers, crutches or
Ocular fathers may wheelchairs to help
alterations. have a with mobilty.
Hearing loss. slightly
Hearth and lung increased risk
problems. of passing on
new genetic
mutations to
their
offspring.
Rheumatoid arthritis
Scleroderma Joint pain. Genetics: Gender Is based on Cyclophosphamide
Skin rashes or There Age laboratory findings followed by
ulcers. appears to be Enviromental and other maintenance with
Stiff joint. a genetic factors complementary mycophenolate
Dry mouth. predisposition Genetic investigations. mofetil.
Difficult breath. to factors
Headache. scleroderma, Race
Weight losse. as the disease
Chronic cough. can run in
families.
Vascular
Abnormalities
Mixed connective tissue Overall feeling of Is an Of any age. Laboratories Corticosteroids.
disease malaise. autoimmune Women exams. Immunosuppressants
Cold and numb disorder, under age of
fingers or toes. although the 50.
 Swollen fingers exact cause
or hands. isn’t known.
Muscle and joint
pain. Family
Rash history.

Takeaways

The connective tissue provides support all the organs of the body, so it’s necessary to maintain the
body in a health state. There are a lot of disorder that affects this important tissue and
understanding connective tissue disorders is critical for timely diagnosis, effective management, and
improved quality of life for individuals affected by these conditions. Also, to prevent damage in
other system, because as I said the connective tissue forms a great portion of the body.