The Smooth Resilient HA Filler from LG

Smooth Resilience
Lifting & contouring
HICE®, a paradigm shift from LG in the manufacturing The highest cross-linking efficiency among HA fillers
technology of hyaluronic acid Yvoire offers an optimal cross-linking ratio (CrR). Not only does this ratio minimize the
With 30 years experience, LG crafts the highest molecular weight HA chains that assure enhanced amount of free BDDE, but it also contributes to a stable molecular structure that resists
cross-linking, higher rheological properties, and consequently better lifting & volumizing performance enzymatic decomposition

Long Chain HA Highest elasticity G’ High CrR*

M.W = 3 Mill Dalton 561 Pa* ~30%

Others
Short Chain HA Modest elasticity G’ Others Low CrR**
M.W =Up to 1 Mill Dalton 219 to 291 Pa ** 10 to 20%

High lifting capacity Deformation resistance High volumizing capacity High Enzymatic Resistance Extended Longevity

Others
Long Chain HA Short Chain HA Fitted grip, no slip

Less BDDE needed More BDDE needed

When it comes to Low MoD = 1.9%* mol High MoD = 6 - 12.8%*** mol Assist-Y Syringe
Leakage-proof
screw tip
biocompatibility...less is more Designed for precision
Yvoire HA chains have high molecular by matching the
anatomy of your hand
weight & long structure which require
only a minimal amount of BDDE for an Break-resistant
efficient cross-linking polymer

Cutting-edge dual particles size composition

Optimal Biocompatibility
Extrusion Force (Avg) = 12 N
Small
Post-treatment Comfort particles
Smooth Flow
Large
Small particles of cross-linked particle
HA fill the voids to assure
Consistent Injection
smooth injection flow
Plast Reconstr Surg Glob Open 8;2020:e2648
* Rheological metrics based on 0.02 Hz and and room temperature
** Prime Journal, 76-73:(2)9;2019 "Data were measured at 0.02 Hz (Frequency sweep mode, 25°C, strain 4%)"
* Prime Journal, 76-73:(2)9;2019
*** Range of monophasic fillers
** Galderma’s patent, WO 206701/2014 A1. Diagram by LG Chem on the comparison of cross
linking ratio of commercially available HA-gels
 Full Line-up*

Product

Gel Type

Main Particle Size

HA concentration

Lidocaine concentration

Degree of Modification

Elasticity (G’ at 0.02 Hz) 341 Pa 424 Pa 561 Pa

Lifting Capacity

Needle

Treatment Areas

Glabella lines Lip Augmentation Jowl Line

Crow’s feet Lip Contouring Cheeks
Tear trough Cheeks Chin Augmentation
Barcode lines Nasolabial Folds
Marionette Lines
Temple
Nose Augmentation
Forehead Augmentation

* Rheological metrics based on 0.02 Hz and and room temperature

Food & Drugs Administration, Drug Masters File – USA, European Directorate for the Quality of Medicines & Health

For further information about Yvoire, please visit our website www.imdad.com or contact us on

riyadh +966 11 465 0371 jeddah +966 12 639 8200 madina +966 14 813 2302 khobar +966 13 894 5015
qassim +966 16 326 5404 khamis mushait +966 17 237 0072 dubai +971 4 451 4455 abu dhabi +971 2 674 6493
kuwait +965 2 225 0206 manama +973 1733 1046 doha +974 4441 6893 muscat +968 24 297 816
beirut +961 1 998 189 amman +962 6 553 9977 cairo +20 2 23067378 other countries +971 4 451 4455