COMPANY PROFILE

PFIZER

Year Started: 1849

No. of years in business: 174 years

Founders: Charles Pfizer & Charles Erhart

Current head: Albert Bourla (Chairman & CEO)

Original location: Red brick building in

Current location: 235 East 42nd Street in Brooklyn neighborhood of Williamsburg, New York, NY 10017,
United States

TIMELINE

1849

• Charles Pfizer and Charles Erhart, the two recent German immigrants cousins to the USA, began to
establish the Pfizer Company in Brooklyn, New York, United States.

• By responding to the American government's request to develop a method for generating penicillin in
large quantities during World War II, Pfizer helped usher in the era of modern medicine.

1861

• The subsequent demand during the American Civil War such as disinfectants, preservatives, and
painkillers doubled the company’s revenue and enabled the company for its continuous expansion.

1868

• As a result of the company’s existence, Pfizer buys and renovates a post-Revolutionary-era building in
Manhattan and preferably moves its headquarters to that area. Therefore, the company has an increased
product line and hired 150 new employees.

1877

• The manufacturing of straight razors began in 1877.

1880

• Production of citric acid

1881
• Pfizer relocated its corporate offices to 81 Maiden Lane in Manhattan, foreshadowing the company's
expansion to Chicago a year later.

1882

• The company started its first operation outside New York due to its expansion in the west of
Mississippi, also to its growing number of clients.

1898

• Expansion of lab and factory

1900

• Pfizer was primarily focused on producing chemicals and pharmaceuticals. Some of the notable
products they produced this year were citric acid, sodium bicarbonate, and various types of medicinal
extracts.

• Pfizer officially incorporated in the State of New Jersey by filing a certificate of incorporation as Charles
Pfizer & Company Inc. that details its authorized capital of $2 million, which was split into 20,000 shares
of $100 each.

• The company was also expanding its operation globally, with a focus on expanding into international
markets such as Asia and Europe.

1908

• The company was acquired by Gustavus A. Pfeiffer & Company who was a patent medicine company
from St. Louise.

1914

• In Chicago, John Anderson founded the first office of the business.

1919

• In order to break Pfizer's dependence on European citrus producers, Pfizer's Christ James Currie and
his assistant, Jasper Kane, pioneered the bulk manufacture of citric acid from sugar using mold
fermentation.

• Pfizer chemists discovered a fungus that converts sugar into citric acid, and they were able to
commercialize citric acid manufacturing from this source. As a result, the business acquired competence
in fermentation technology. These abilities were put to use in the mass manufacture of the antibiotic
penicillin during World War II in order to treat wounded Allied soldiers.

1936

• Pfizer became the world's largest manufacturer of vitamin C. Doctor Richard Pasternack created a
fermentation-free process for synthesizing ascorbic acid, or vitamin C.

1938
• Pfizer’s production of vitamin B-2 or the riboflavin pushes ahead and the company develops the
vitamin matrix that includes riboflavin, thiamin, niacin, and the iron.

1939

• The Pfizer Company succeeds in the production of citric acid through fermentation. Hence, it has been
widely recognized as a leader in fermentation technology.

1941

• Pfizer responds to a request from the US government to hasten penicillin production in order to treat
Allied soldiers battling in World War II.

June 2, 1942

• When the company incorporated in Delaware.

1944

• Pfizer has successfully become the world’s largest producer of “miracle drugs”.

1950

• The first drug to be released in the United States under the Pfizer label is a broad-spectrum antibiotic
called terramycin. Pfizer also starts to expand into foreign markets at this time, and the International
Division is established.

• Discovery of ox tetracycline

1951

• In a major international expansion, Pfizer operations are established in Belgium, Canada, Cuba,
England, Mexico, Panama, and Puerto Rico.

1952

• The company established an Agricultural Division which was dedicated to offering cutting-edge
solutions to animal health problems.

1955

• The Pfizer Company has acquired fully the ownership of Taito, which they were partners as a
manufacturer and distributor of antibiotics before.

• Pfizer introduced a new product called Lederle Laboratories' Sulfadiazine

1958

• The new Pfizer pharmaceutical plants started production in Mexico, Italy and in Turkey. In addition, the
international personnel increased from 4,3000 in 1957 to over 7,000.

1960
• The Company has centralized its medical research laboratory activities in Groton, Connecticut, as a
reflection of its growing dedication to research.

1961

• Pfizer begins a decade of substantial growth and establishes a new World Headquarters in midtown
Manhattan.

• Pfizer introduced a new product called Chloromycetin

1967

• Vibramycin has been introduced quickly and became a top seller.

1971

• Pfizer introduced a new drug called Dipyridamole

1972

• Pfizer introduced a new drug called Feldene

1976

• Pfizer introduced the Minipress in the United States as a control for high blood pressure

• Pfizer introduced a new drug called Zoloft, an antidepressant used to treat major depressive disorder,
panic disorder, and obsessive-compulsive disorder.

1980

• Pfizer’s Feldene product became one of the largest-selling prescriptions in anti-inflammatory

medications in the world and it became the first product that reached a total of a billion United States
dollars in sales.

• Pfizer acquired Warner-Lambert, a leading pharmaceutical and consumer products company

1981

• The company received approval for Diflucan (fluconazole), the first oral treatment for severe fungal
infections.

• Pfizer received FDA approval for a new drug called Procardia, a calcium channel blocker used to treat
high blood pressure and angina.

1985

• One of the first big prescription pharmaceuticals to receive direct-to-consumer advertising was
Seldane.

1986

• Acquired worldwide rights of azithromycin.

• Pfizer introduced a new drug called Norvasc, a calcium channel blocker used to treat high blood
pressure and angina.

1989

• Viagra was created for treating high blood pressure and angina, a chest pain associated with coronary
artery disease.

• Pfizer introduced a new drug called Lipitor, a statin used to lower cholesterol levels and reduce the risk
of heart disease

1990

• Pfizer International launched 37 new products worldwide.

1991

• Started marketing Zoloft.

1993

• Sales have declined during this year.

1994

• Pfizer introduced a new drug called Viagra, a treatment for erectile dysfunction.

1996

• Viagra was patented in Unites States.

• Pfizer introduced a new drug called Zithromax, a macrolide antibiotic used to treat a variety of
bacterial infections including respiratory and skin infections.

1997

• The company entered into a co-marketing agreement with Warner–Lambert for Lipitor (atorvastatin).

• Pfizer acquired pharmacia, a leading pharmaceutical company.

1998

• In March 1998, Pfizer receives approval for Viagra.

• Pfizer introduced a new drug called Celebrex, a COX-2 inhibitor used to treat pain and inflammation
associated with conditions such as osteoarthritis and rheumatoid arthritis.

2000

• The biggest merger in global pharmaceutical history took place when Pfizer acquired Warner Lambert

• The company became number one in the cardiovascular business owing to its "crown jewels", Norvasc
and Lipitor

• Pfizer received FDA approval for a new drug called Sutent,

2001

• Pfizer is Ranked the Largest Corporate Donor in the United States

• Pfizer received FDA approval for a new drug called Lipitor

2002

• Pfizer became the top-selling medication worldwide is Lipitor from Pfizer.

• Pfizer became the largest pharmaceutical company in the world.

April 16, 2003

• Pfizer Inc. and Pharmacia Corporation merged their operations, joining two of the most creative and
rapidly expanding businesses in the world.

• Pfizer acquired Pharmacia Corporation and officially combined operations in April 2003

• Pfizer introduced a new drug called Lyrica

2004

• The company received approval for Lyrica (pregabalin) and Viagra

2005

• Lyrica (pregabalin) is the first medication authorized by the US Food and Drug Administration to treat
neuropathic pain associated with diabetic peripheral neuropathy (DPN) and postherpetic neuralgia
(PHN), and adjunctive therapy of partial onset seizures in individuals with epilepsy.

2006

• Torcetrapib, a medication that boosts the production of HDL, or "good cholesterol," and lowers LDL, a
lipid suspected to be associated with heart disease, was no longer being developed by Pfizer as of
December 3,

• Pfizer obtain the results of a clinical trial for its new drug, Sutent, which showed that it could
significantly extend the lives of patients with advanced kidney cancer

2007

• The Human Rights Campaign has honored Pfizer for its policies and programs that support the LGBT
community

• Pfizer restructures its operations to focus on its core pharmaceutical business

2008

• Pfizer acquired Coley Pharmaceutical Group's Canadian subsidiary 13

2009

• In October 15, Pfizer acquired Wyeth

2010

• Pfizer acquired Synbiotics on Dec 30, 2010. It is a manufacturer and supplier of diagnostics products for
livestock. It is located at Kansas City (United States, est.1982)

2011

• Pfizer acquired Icagen on Oct. 27, 2011, for $27.5M. It is a CRO for ion channel and transporter drug
discovery and development. It is located in Raleigh (United States, est. 1992) • Pfizer also acquired
Excaliard Pharmaceuticals on Nov 22, 2011, for $15.5M. It develops drugs for the local treatment of
scarring and skin fibrotic diseases. It is located in Carlsbad (United States, est. 2006)

2012

• Pfizer acquired Emergen-C on Feb 27, 2012. It manufactures a variety of branded dietary supplements.
It is located at Lake Forest (United States, est. 1972) • Pfizer acquired Alacer on Feb 27, 2012. It is a
manufacturer of vitamin, mineral, protein, and probiotic supplements & foods. It is located at Carlisle
(United States, est. 1978)

2014

• Pfizer acquired Innopharma, a Biopharma company focused on manufacturing generic and specialty
products located in Piscataway (United States, est. 2005) for $360M on Jul 16, 2014. It is also a
Manufacturer of injectable pharmaceutical products

2015

• Pfizer acquired Hospira, a manufacturer of injectable drugs, infusion technologies, and biosimilars
located at Lake (United States, est. 2004) on Feb 05, 2015, for $17B.

2016

• Pfizer acquired Anacor Pharmaceuticals, a Topical & small-molecule therapeutics derived from its
boron chemistry platform for the treatment of infectious 7 autoimmune diseases located at Palo Alto
(United States, est. 2002) for $5.2B on May 16, 2016.

• Pfizer acquired Bamboo Therapeutics, a Developer of gene therapies to treat rare central nervous
system and neuromuscular diseases located at Chapel Hill (United States, est. 2014) on Aug 01, 2016.

• Pfizer acquired Medivation, a Developing small molecule and antibody therapeutics for cancer located
in San Francisco (United States, est. 2004) on Aug 22, 2016, for $14.3B.

2019

• Pfizer acquired TherAchon, a Developer of recombinant protein therapy for treating achondroplasia
located at Basel (Switzerland, est. 2014) on May 08, 2019, for $340M.

• Pfizer acquired Array BioPharma, a Speciality biopharma company focused on developing small
molecule drugs for the treatment of cancer on Jun 17, 2019, for $11.4B.

2020
• As the scope of the COVID-19 pandemic became clear in March 2020, Pfizer joined together with
BioNTech to research and create COVID-19 mRNA vaccine candidates. Moreover, the vaccine was safe
and had a 95% effectiveness rate, according to data from Phase 3 clinical trials, the manufacturer
reported in November 2020.

2021

• Pfizer acquired Amplyx Pharmaceuticals, a US-based, clinical-stage biopharma developing

broadspectrum small molecule fungal enzyme inhibitor on Apr 28, 2021.

• Pfizer acquired Trillium Therapeutics, a Developer of therapeutics for the treatment of cancer on Aug
23, 2021, for $2.2B.

• Pfizer acquired Arena Pharmaceuticals, a clinical-stage biotech focused on cardiovascular,

autoimmune, inflammatory, and metabolic diseases on Dec 13, 2021, for $6.7B.

2022

• In order to increase access to vaccines and treatments for people all over the world, Pfizer has taken
the lead in the development of a vaccine and treatment in response to the COVID-19 pandemic.

2022 – 2023