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Spectrum of CT Find - Ings in Rupture and Impending Rupture of Abdominal Aortic Aneurysms
Spectrum of CT Find - Ings in Rupture and Impending Rupture of Abdominal Aortic Aneurysms
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Spectrum of CT Find-
ings in Rupture and
Impending Rupture
of Abdominal Aortic
Aneurysms1
Dmitry Rakita, MD ● Amit Newatia, MD ● John J. Hines, MD ● David N.
ONLINE-ONLY
CME Siegel, MD ● Barak Friedman, MD
See www.rsna
.org/education
/rg_cme.html. Prompt diagnosis of rupture and impending rupture of abdominal aor-
tic aneurysms is imperative. The computed tomographic (CT) find-
ings of ruptured abdominal aortic aneurysms are often straightforward.
LEARNING
OBJECTIVES Most ruptures are manifested as a retroperitoneal hematoma accompa-
After reading this
nied by an abdominal aortic aneurysm. Periaortic blood may extend
article and taking into the perirenal space, the pararenal space, or both. Intraperitoneal
the test, the reader
will be able to: extravasation may be an immediate or a delayed finding. Discontinuity
䡲 Recognize the im- of the aortic wall or a focal gap in otherwise continuous circumferential
aging features of in-
stability, impending wall calcifications may point to the location of a rupture. There usually
rupture, and rupture is a delay of several hours between the initial intramural hemorrhage
of abdominal aortic
aneurysms.
and frank extravasation into the periaortic soft tissues. Contained or
䡲 Describe the utility impending ruptures are more difficult to identify. A small amount of
of gadolinium as a periaortic blood may be confused with the duodenum, perianeurysmal
contrast agent for
CT angiography. fibrosis, or adenopathy. Imaging features suggestive of instability or
䡲 Identify the etiol- impending rupture include increased aneurysm size, a low thrombus-
ogy and imaging to-lumen ratio, and hemorrhage into a mural thrombus. A peripheral
features of infected
abdominal aortic an- crescent-shaped area of hyperattenuation within an abdominal aortic
eurysms and aorto- aneurysm represents an acute intramural hemorrhage and is another
enteric fistula.
CT sign of impending rupture. Draping of the posterior aspect of an
aneurysmal aorta over the vertebrae is associated with a contained rup-
TEACHING ture.
POINTS ©
RSNA, 2007
See last page
Introduction
Most abdominal aortic aneurysms are true aneu-
rysms. A true aortic aneurysm is a localized dila-
tation of the aorta caused by weakening of its
wall; it involves all three layers (intima, media,
and adventitia) of the arterial wall. A pseudoan-
eurysm (false aneurysm) is a collection of flowing
blood that communicates with the arterial lumen
but is not enclosed by the normal vessel wall; it is Figure 1. Types of aortic aneurysms. Schematic de-
contained only by the adventitia or surrounding picts the normal arterial wall structure and the wall
soft tissue (Fig 1). Aneurysms may develop in any structures of true and false aneurysms.
segment of the aorta, but most involve the aortic
segment below the renal arteries. An aortic diam-
eter of 3 cm or more is used to define an abdomi- less convenient. Ultrasonography (US) plays a
nal aortic aneurysm (1). Aneurysmal dilatation of limited role in the assessment of acute aortic ab-
the abdominal aorta is a disease of aging and is normalities. Frequently, the entire aorta cannot
rare before age 50 but is found in 2%– 4% of the be evaluated because of overlying bowel gas and
population older than 50 years (2). The average body habitus. In addition, US is operator depen-
age at the time of diagnosis is 65–70 years, and dent, and the necessary expertise may not be
more men than women are affected. Concurrent readily available. A bedside examination with US
coronary artery disease and peripheral vascular may be helpful for patients whose condition is too
disease, as well as a family history of abdominal unstable to allow their transfer to the CT scanner.
aortic aneurysm, are strong risk factors for the US may help determine the size of the aneurysm
development of this condition. and help identify hemoperitoneum. However, the
A retroperitoneal hematoma adjacent to an utility of US for identifying an impending rupture
abdominal aortic aneurysm is the most common or a contained rupture of an aneurysm is limited.
imaging finding of rupture (3). Extension of hem- The use of CT angiography has become rou-
orrhage into the retroperitoneum, including the tine for imaging of a suspected abdominal aortic
perirenal and pararenal spaces, psoas muscles, aneurysm rupture. Because the clinical signs and
and peritoneum, is a common occurrence. Intra- symptoms frequently are confused with those of
peritoneal extravasation may be an immediate or appendicitis, pancreatitis, or bowel obstruction,
a delayed finding. abdominal aortic aneurysm rupture sometimes is
Patients who present with abdominal pain, a detected at a nonemergent CT evaluation for
large abdominal aortic aneurysm, and no frank nonspecific abdominal pain or renal colic.
rupture pose a diagnostic dilemma. The symp- Unenhanced CT may help detect an aneurysm
toms may be attributable to aneurysmal instabil- rupture by depicting an abdominal aortic aneu-
ity, impending rupture, or a contained leak. rysm with surrounding retroperitoneal hemor-
rhage. Contrast-enhanced CT provides additional
Imaging Techniques information about the size of the aneurysmal lu-
Computed tomography (CT) is the modality of men, presence of active extravasation, and rela-
choice for evaluation of acute aortic syndrome, tionship of the aneurysm to the celiac, superior
because of the speed of the examination and the mesenteric, renal, and inferior mesenteric arter-
widespread availability of CT. With a multidetec- ies. Our abdominal aortic aneurysm CT protocol,
tor CT scanner in the emergency department, an performed on a four– or 16 – detector row scan-
examination can be performed and the images ner, consists of unenhanced scanning through the
interpreted within minutes. Magnetic resonance abdomen and pelvis at 5-mm collimation, fol-
(MR) imaging requires a much longer acquisition lowed by bolus-tracked CT angiography of the
time, and MR imaging may be less available and abdomen and pelvis at 1-mm collimation and
then by delayed imaging of the abdomen and pel-
vis in the portal venous phase (80 seconds) at
5-mm collimation. The acquisition of thin sec-
tions is essential for multiplanar reformatting,
RG f Volume 27 ● Number 2 Rakita et al 499
Figure 2. Aortic aneurysm rupture in an 80-year-old woman with abdominal pain and hypotension.
Axial (a) and sagittal (b) CT angiographic images demonstrate active extravasation of contrast material
(arrow) into the thrombosed portion of an abdominal aortic aneurysm, as well as extensive retroperito-
neal hemorrhage (arrowhead).
Figure 3. Aortic aneurysm rupture in a 67-year-old man with abdominal pain and hypotension. Axial
CT angiographic images depict a large ruptured abdominal aortic aneurysm with active retroperitoneal
extravasation (arrow in a) and intraperitoneal hemorrhage (arrow in b).
evaluating the relationship of the aneurysm to Periaortic blood may extend into the
other abdominal vascular structures, and plan- perirenal space, pararenal space, or the psoas
ning endovascular stent-graft placement. Con- muscles. Intraperitoneal extension may be an im-
trast injection rates of 3– 4 mL/sec are optimal; mediate or a delayed finding. These findings are
however, slower rates of 1.5–2 mL/sec yield im- readily visible on unenhanced CT images, which
ages with diagnostic quality. A total of 90 mL of may have been obtained for another indication or
nonionic intravenous contrast material is suffi- as part of an aneurysm evaluation protocol. On
cient to reliably produce diagnostic-quality im- contrast-enhanced CT images, active extravasa-
ages. Oral contrast material is not administered. tion of contrast material is frequently demon-
strated (Figs 2, 3). Although open surgical tech-
Findings of Aneurysm Rupture niques have traditionally been used to repair
A retroperitoneal hematoma adjacent to an ab-
Teaching dominal aortic aneurysm is the most common
Point imaging finding of abdominal aortic aneurysm
rupture (3).
500 March-April 2007 RG f Volume 27 ● Number 2
Figure 6. Draped aorta sign in a 55-year-old man with a known abdominal aortic aneurysm and recent
vague back pain. Axial CT angiographic images (a at a level higher than b) depict an 8-cm abdominal
aortic aneurysm with a posterior aortic wall that follows the contour of the vertebral bodies with a drap-
ing effect (arrow in b). The latter finding is indicative of a contained rupture.
Figure 7. Large ruptured aneurysm in a 68-year-old man with an acute onset of right flank pain radiat-
ing to the back. Axial unenhanced CT images (a at a level higher than b) depict a ruptured 10.7-cm ab-
dominal aortic aneurysm and a retroperitoneal hemorrhage (arrow).
Figure 9. Impending aneurysm rupture in a 66-year-old man with back pain, who underwent imaging
for suspicion of renal colic. Axial unenhanced CT images (a and b are the same section with different
window settings) demonstrate an abdominal aortic aneurysm with a hyperattenuating crescent sign (ar-
row) that represents an acute hematoma within the aneurysm wall.
Figure 10. Impending aneurysm rupture in a 57-year-old man with a known abdominal aortic aneu-
rysm and increasing abdominal pain. Axial unenhanced (a) and axial contrast-enhanced (b) CT images
depict an abdominal aortic aneurysm with a hyperattenuating crescent sign (arrow in a), which repre-
sents an acute hematoma within the aneurysm wall.
ing aneurysm size (11). These observations sug- Hyperattenuating Crescent Sign
gest that a thick circumferential thrombus is pro- A well-defined peripheral crescent of increased
Teaching
tective against rupture. In addition, enlargement attenuation within the thrombus of a large ab-
Point
of the patent lumen is indicative of partial lysis of dominal aortic aneurysm is a CT sign of acute or
the thrombus, which predisposes an aneurysm to impending rupture (13,14). This finding is best
rupture (11,12). appreciated on unenhanced CT images (Figs 9,
A focal discontinuity in circumferential wall 10). It represents an internal dissection of blood
calcifications is more commonly observed in un- into either the peripheral thrombus or the aneu-
stable or ruptured aneurysms (3). This finding is rysm wall, a process that either causes or results
most helpful when a previous CT study is avail- from a loss in the ability of the thrombus to pro-
able and its comparison with the current CT tect the aneurysm from rupture (15). It is one of
study shows that an area of discontinuity in mural the earliest and most specific imaging manifesta-
calcifications is new (Fig 8). tions of the rupture process (3,13–15).
504 March-April 2007 RG f Volume 27 ● Number 2
Aortoenteric Fistulas
Primary aortoenteric fistulas are a complication of
Teaching
atherosclerotic aortic aneurysms, whereas second-
Point
ary aortoenteric fistulas are a complication of aor-
tic reconstructive surgery (17). Most fistulas in- Surgical exploration is usually necessary
volve the duodenum, most commonly its third to confirm the diagnosis and for treatment.
and fourth portions. Symptoms include abdomi- Secondary aortoenteric fistulas are much more
nal pain, hematemesis, and melena. common and must be distinguished from graft
Primary aortoenteric fistulas may pose a diag- infection, since perigraft gas may be seen in both
nostic dilemma for the clinician, especially in the conditions and since both entities may occur as
absence of gastrointestinal tract bleeding. Upper- delayed complications of aortic aneurysm repair.
gastrointestinal-tract endoscopy may help rule Aortoenteric fistulas have been reported to oc-
out other causes of bleeding but rarely helps diag- cur between 2 weeks and 8 years after surgery
nose a fistula. CT imaging features include an (17,18).
abdominal aortic aneurysm, often with signs of
rupture, and intraluminal and periaortic extralu-
minal gas (Fig 13). CT with the use of intrave-
nous contrast material may show contrast mate-
rial extravasation from the aorta into the involved
portion of the bowel, if a patent fistula is present
(17,18).
506 March-April 2007 RG f Volume 27 ● Number 2
Figure 13. Aortoduodenal fistula in a 71-year-old woman with a known abdominal aortic aneu-
rysm, abdominal pain, and a guaiac-positive stool test. Axial (a, b), close-up axial (c), and coronal (d)
CT angiographic images depict small gas bubbles within a ruptured aneurysm sac (arrows in a, b,
and d), as well as disruption of the anterior aortic wall, with a faint fistulous tract between the
thrombosed portion of the aortic aneurysm and the third portion of the duodenum (arrowhead in b
and c). The differential diagnosis included aortoduodenal fistula and mycotic aneurysm. The pa-
tient died of a massive gastrointestinal hemorrhage the next day.
Figure 14. Inflammatory aneurysm in a 50-year-old man with a known abdominal aortic aneurysm,
abdominal pain, and an elevated erythrocyte sedimentation rate. Axial contrast-enhanced CT images (a
at a level higher than b) demonstrate a large abdominal aortic aneurysm with circumferential perianeu-
rysmal fibrosis and inflammation (arrow).
This article meets the criteria for 1.0 AMA PRA Category 1 Credit . To obtain credit, see www.rsna.org/education
TM
/rg_cme.html.
RG Volume 27 • Volume 2 • March-April 2007 Rakita et al
Page 499
A retroperitoneal hematoma adjacent to an abdominal aortic aneurysm is the most common imaging
finding of rupture.
Page 500
An important imaging feature that may be seen in a contained rupture of an abdominal aortic
aneurysm is the draped aorta sign. This sign is considered present when the posterior wall of the aorta
either is not identifiable as distinct from adjacent structures or when it closely follows the contour of
adjacent vertebral bodies (Fig 6).
Page 503
A well-defined peripheral crescent of increased attenuation within the thrombus of a large abdominal
aortic aneurysm is a CT sign of acute or impending rupture.
Page 504
CT findings of infected aneurysms include a saccular shape; lobular contours; and periaortic
inflammation, abscess, and mass. Other findings include periaortic gas and adjacent vertebral body
abnormalities due to the spread of infection (Figs 11, 12).
Page 505
Primary aortoenteric fistulas are a complication of atherosclerotic aortic aneurysms. CT imaging
features include an abdominal aortic aneurysm, often with signs of rupture, and intraluminal and
periaortic extraluminal gas (Fig 13). CT with the use of intravenous contrast material may show
contrast material extravasation from the aorta into the involved portion of the bowel, if a patent fistula
is present.