M N AE c T O R T T S

ischemichea
disech
Ansina ig Sudden Seuehe pr
Chhactaisecl
lelt
2odieting to weck
chest puin
leCAxn)
9hauld eh, ancd

Myacnh i onSum ptno isbabed upan

Venovs ehhn and Shrethinq at
hts
pxe looc
lath looo pehiphthal ostehicu 2esistancean
Hes hare

Sueply leas 1schemiq

Antitaoginal M-a.A =_
a Tmve 2_lem_dadat heid lhy oskectia RP

Heant Cntxocili

ype claksical angin4 /2)y-iest Ongin9

2classica anginq tahle onging Cn ina ot elat

ain whlth 1g Incluced hyexexcise ia bch
myocada Op demanc a t

N.Sawing at hanh4 atihy due to athexosclehosi

ahher lz inGutticien Supply
dudunethcise
 Hente thexe Ig imba ante hetween z Supplyand
dem.an.cl uinOCCuX

Vaueat0 Pxi02me tol'g Cngioa

is Cause by Spam ot the Cunanoy at
ehy
Davg Meshanis M
Dxvg Use to impxove the
Supply CLod olem.onge buan cobetween
myat.h diun O eithhhy1e2 t
by v 2 elema paeluuel dtlaad
niongin ou Dug
uixodes
Shuht qcing (NTn)
Nitzogycehiogivea suhLaua
T9a Saxbiode oli
nitx.ode
TSoSoxbide Mo.n.onitxate ivea
3Calcium chonne blo.clke scully)
VeXy Veh op
am
Nite Niti dipio
Ohus oltia zem
 OB-blockex PA
PopXanolal otenolol

sPotassium channel openeh

PatasSiu ke
Iye NiCo_ CLU MIXo Mloo

USe KSO MinoXio)

other elhus
ASpixio KanotezineIvahxaoloe
LyH-R&

TTRATE
Mechanlam TM
OAtSates aOe yagaddilato

ityate Mtic oXidle

Vos Cuwah n d o h e h u m

rUayty yei VaSculah Smoath

museP.
ACAA-ChMP
93whesis CGnTP coMe
of erenid

dephosp- VACine Myin + Free yto solic Co

and ause igtexqctioo CPevephelease-o Cal
SwCopl oSmic yethculum
hoxg)on of Psote ro m&e
Kin usr
SM0oth Muscle Keludediuo
 Da
C l e :

DTo Vehieo+ ang lng nitx ate elieve VdoSpa%o

olwe to CoXanchy VaSodiladion

Adve xse eftectL

Head cuche hecuse_ot alldti on 1nmeningea veßSel)
Sweating
p cdptdion
wea knes S

Ugeg
Acute anqina Suhkngual nltzoglycho is qiveo
Relieua pauOin 3 minutes

Cdiac Fulme pravideVeodblatorpzapoh Ey-

(9Mocccli c ToExacton

nlple polS.aingi
yunidehind with CytochXome oXLde and block
ilizadion ut a Xygan
Amyloitxate 19 9iven by lohaledion no fux lmmediade
trecdment

oCium ChaAnel Black 8

S i o n o t Lchdliac cao /oSeula Smaoh

depala
C
muscledepend et on enteu ot extxncellaleh
ioto ntracetuulel hYuugh Co CLunnchosnne
 This ndracelUulah Cotzlgohhelecsdatmo2e
Ca tron c9coplo Spalc reciwlum CALL this Co
CcLu Se (ontsacho0
ccBinhibit the entoy t Co by blaking dhe
Chonnels
Th i9 hesut 1ato, SMooh muscle Reloxadion
BP PuR myothela CantxocHilty
VH-R Coxoniuy blood Elow
E CCR e u8etul10 Vaimt hpe t anp0
CB_clhug ochon
OVexapami
pXomote Myocaholiac depXe SSantaChan
E Shouldnot Cambined iith $-bla.ck.ehL

AdvehSe_etlect bhasyccia hypoten Sion

Lanstipahon Cdue do R.poh
adgedba)
Nite dipine io
T 19 patet vaboeli/adtu) cause18p ancd 1 hzsd
nate Myacchdioc olepresSont fsweak
given Subliagually4
Adva xse eftet Headlacha, palplkdiun, fadh gue, aliziness
9 ot CCBs 2
Oischemic heat oluse.a8&
velamomil dultlazen u& ln stahle angina hey
Paun, and spa3m_1n_Naospahc angina
 Vexamami ig S.ol inunsdo ble Ongina-

(Hpextension
Maxone vexapami) is uSed
Ath exo sclexosis
Sub.axachnal.c hemaxxhogeit actUS cue uVbo Spasm
Aimadi pine 18 qiven In this
Dlexeha Val Socdildiun ch ii

5. blackhS
Exexcise emotion anc Similo giHuccion
ympathetie actvi heat Yate an
B.e
Due to thi O_Consumptun i8 ls.o 1byhea
B-lock e blnck cu dhase Cctions and pxeveot onql109

Adver se etteet Not Se to ioVauant angina

_chaaae oPneh-
Elopeninq
K Channel esult 10 hype palahiz.octlon
ReX ation ot Vabculcd Smuoth nuscle
Veiso-F
ViczpIunot19 ig givm ellato
Nitaic oXid

A0vezse etect a heusache oiz2iness hypotm.Sian

u g e - Tre adment ot cun giaa
Dose 10-2o m tuulce dauly