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Chem 6
Chem 6
Chem 6
What is a drug?
It is any substance (with the exception of food and water) which, when taken into the body, alters the
body’s function either physically and/or psychologically.
Dosage/Dose
it is the amount of drug taken at one time
Type of Dosage
a. Minimal – it refers to the amount needed to treat or heal, that is, the smallest amount of drug that will
produce a therapeutic effect.
b. Maximal – it pertains to the largest amount of drug that will produce a desired therapeutic effect,
without any accompanying symptoms of toxicity.
c. Toxic - it is the amount of drug that produces untoward effects or symptoms of poisoning.
d. Abusive – the amount needed to produce the side effects and action desired by an individual who
improperly uses it.
e. Lethal– the amount of drug that will cause death.
Toxicology
- the science of poisons, their effects and antidotes.
Toxic effects a drugs may caused
a. Overdose – when too much of a drug is taken into the physiological system of the human body, there
may be an extension of its effects.
b. Allergy – some drugs cause the release of histamines giving rise to allergic symptoms such as
dermatitis, swelling, falls in blood pressure, suffocation and death.
c. Idiosyncrasy – it refers to the individual reaction to a drug, food, etc. for unexplained reason.
d. Poisonous property – drugs are chemicals and some of them have the property of being general
protoplasmic poisons.
e. Side effects – some drugs are not receptors for one organ but receptors of other organ as well. The
effects in the other organs may constitute a side effect, which are most of the time unwanted.
Dangerous drugs
These are drugs that are attended by risk and therefore unsafe, perilous, and hazardous to people
using it.
These are strictly prohibited that possession of them is punishable.
Pharmacology
simply means as the study of how a drug affects the body.
Opium
It is extracted from the coagulated juice poppy plant
Meconic Acid is the active ingredient and analgesic property of Opium.
Derivatives of Opium
Morphine – principal derivative of opium
Heroin – second derivative and the most addicting opium derivative
Codeine - A derivative of morphine commonly available in cough preparations
STIMULANTS (UPPERS)
These are drugs that produce excitation, alertness, and wakefulness, intense feeling of “highness” and
in some cases, a temporary rise in blood pressure and respiration.
It works by increasing the activity of the brain chemicals dopamine and norepinephrine. Dopamine is
involved in the reinforcement of rewarding behaviors. Norepinephrine affects blood vessels, blood
pressure and heart rate, blood sugar, and breathing.
Cocaine, Amphetamines, Methamphetamine Hydrochloride, Flakka, Caffeine
DEPRESSANTS (DOWNERS)
These are drugs which suppress vital body functions especially those of the brain or central nervous
system with the resulting impairment of judgment, hearing, speech, and muscular coordination.
They dull the minds, slow down body reactions to such an extent that accidental deaths/or suicides,
usually happen.
Barbiturates, Methaqualone, Mandrax, Tranquilizers
Alcohol - It is considered as the ‘king’ of all drugs and most extensively legalized drugs throughout the world
Inhalants - The inhalation of solvent fumes from glue, gasoline, and paint thinner and lighter fluid will
produce a form of intoxication.
HALLUCINOGENS (PSYCHEDELIC)
A variety or mind- altering drugs which distort reality, thinking and perception of time, sound, space
and sensation. It usually affects the user by Hallucination, Illusion and Delusion.
Hallucinogens interfere with the action of the brain chemical serotonin, which regulates mood,
sensory, and perception.
Cannabis Sativa / Marijuana, Lysergic Acid Diethylamide (LSD), Mescaline, Psilocybin, Ecstasy,
Phencyclidine (PCP)
Synesthesia
experiencing one of your senses through another. e.i. hear colors or see sounds.