Toxicology NRC 58246

Activity Nº1 (Score 50% First Grading Period)

Team members:

1. (2.5/5 Points) Read “Chapter 1 History and Scope of Toxicology” in Casarett

Doulls Essentials of Toxicology (Curtis Klaassen, John B. Watkins III)
provided by the teacher as a PDF file through the News Forum. Make an
autonomous review on the subject, accessing the academic contents of the
Rafael García Herreros Virtual Library. Then, match the items on the right to
the items on the left (Look at the example):

A. Is the study of adverse effects of xenobiotics on living (G) Catherine de Medici

systems.
B. A poison developed in Sicily near 1630. It became a (I) Percival Pott’s
catch-all term referring to an imagined class of “slow
poisons”.
C. An objective of toxicology related to occupational (K) National Institutes of Health (NHI)
health. and Food and Drug Administration
(FDA).
D. Ethanol taken in overdose during the Mother’s Day. (L) Thalidomide

E. The oldest evidence that have been found regarding (F) The writhings of Maimonides
many recognized poisons (Hemlock, Aconite, Opium, and
metals).
F. Includes information on how to treat poisoning by (_A_) Toxicology
insects, snakes, and mad dogs.
G. Under the pretext of delivering food to the sick and the (B) Aqua Tofana
poor, she tested toxic concoctions, carefully noticing the
speed of the toxic response.
H. All substances are poisons, there is none that is not a (J) Radioactive compounds and
poison. The right dose differentiates a poison from a vitamins.
remedy.
I. First report of polyaromatic hydrocarbon carcinogenicity (C) To apply safety evaluation and risk
related of the role of soot in scrotal cancer among assessment
chimney sweeps.
J. Substances assessed in early large-scale bioassays to (H) A statement set by Paracelsus
determine whether they had beneficial or adverse effects
in experimental lab animals.
K. Agencies established in the twentieth century to (D) Acute intoxication
monitor and control the safety and efficacy of substances
on the market.
L. It caused that several thousand children were born with (O) The golden poison dart frog
serious birth defects in the 1960s.

M. It happens after years of drinking too much ethanol (E) Ebers Papyrus
and is a result of a chronic poisoning.
N. Etymology of the word toxicology (N) Toxicon - Logia
O. Used by Indigenous cultures, such as the Chocó (M) Alcoholic Cirrhosis
people of Colombia to coat the tip of their blow darts
before hunting.

2. (2.0/5 Points) Use the following SmartArt to explain how toxicology

helps the development of the Occupational Health and Safety. Present four
statements with their respective argument and bibliographic citation. Base
your arguments on scientific facts and evidence. In the GH virtual library, you
will find a variety of academic documents for you to consult. Use your own
words to build your texts and remember that any kind of plagiarism won’t be
accepted. Textual citations are not allowed as the main goal for this task is
that you develop your writing skills. For explanation about Statement and
Argument please click here. For explanation about Citation and Reference,
please click here.
 3. Bibliographic References (APA Style) (0.5/5 points).

- Repetto Jiménez, M., Repetto Kuhn, G.(2021). Toxicología fundamental. Ediciones Díaz de Santos.
https://www-ebooks7-24-com.ezproxy.uniminuto.edu/?il=13457
- Watkins, J.B. and Klaassen, C.D. (2015) Casarett & Doull's essentials of toxicology III. McGraw-Hill.
(PDF)