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RADIOTHERAPY • Destroy tumors that have not spread to

other body parts.


RADIATION THERAPY
Reduce the risk that cancer will return after
 Is a local treatment modality for surgery or chemotherapy.
cancer and it is the destruction of
cancer cells by ionizing radiation To reduce symptoms:

 Purpose: is to destroy malignant • Shrink tumors affecting quality of life, like


cells which are more sensitive to a lung tumor that is causing shortness of
radiation than are normal cells breath,
without permanent damage to Alleviate pain by reducing the size of a
adjacent body tissues tumor.
 Radiation may be used to cure Types of Radiation Therapy
cancer, as in thyroid carcinomas,
localized cancers of the head and Externally (Teletherapy, DXT) – external
neck, and cancers of the cervix. beam radiation therapy (EBRT)

 Radiation therapy may also be used  Delivers radiation using a linear


to control cancer when a tumor accelerator
cannot be removed surgically or Internally ( Brachytherapy or Seed
when local nodal metastasis is implants)
present.
 Involves placing radioactive sources
Used in three ways: inside the patient.
 Neoadjuvant (prior to local definitive
treatment) radiation therapy, with or EXTERNAL BEAM RADIATION THERAPY
without chemotherapy
 This is administered through a high –
 Radiation therapy may be given energy X-ray or gamma x-ray
prophylactically machine
 Palliative radiation therapy  The major advantage of high-energy
METHODS OF DELIVERING RADIATION radiation is its skin – sparing effect.
THERAPY  EBRT is the most commonly used
HOW IS RADIATION THERAPY USED form of radiation therapy

Radiation therapy is used two different Specialized Types of External Beam


ways. Radiation Therapy (EBRT)

To cure cancer:
 Stereotactic radiosurgery (SRS) is a
non-surgical radiation therapy used
to treat functional abnormalities and
small tumors of the brain.
 It can deliver precisely-
targeted radiation in fewer high-
dose treatments than
Intensity Modulated Radiation Therapy traditional therapy, which can help
(IMRT) preserve healthy tissue.
 A specialized form of 3D-CRT Systems which produce different
 Radiation is broken into many types of radiation for external beam
“beamlets” and the intensity of each therapy include:
can be adjusted individually A) orthovoltage x-ray machines,
B) Cobalt-60 machines,
Proton Beam Therapy C) linear accelerators,
 Uses protons rather than x-rays to D) proton beam machines, and
treat certain types of cancer.
E) neutron beam machines.
 Allows doctors to better focus the
dose on the tumor with the INTERNAL RADIATION THERAPY
potential to reduce the dose to  Places radioactive material into
nearby healthy tissue tumor or surrounding tissue
Neutron Beam Therapy  Also called Brachytherapy – brachy
A specialized form of radiation therapy that Greek for “short distance”
can be used to treat certain tumors that are  Radiation sources placed close to
very difficult to kill using conventional the tumor so large doses can hit the
radiation therapy. cancer cells
Stereotactic Radiotherapy
 Sometimes called stereotactic THE MAJOR TYPES OF INTERNAL
radiosurgery RADIATION THERAPY
 This technique allows the radiation  A. SEALED SOURCE –
oncologist to precisely focus beams (brachytherapy) the radioisotope is
of radiation to destroy certain placed within or near the tumor.*
tumors, sometimes in only one
treatment  - is used for both intracavitary and
interstitial therapy
INTRACAVITY RT is used to treat  Spend less time with the patient
cancers of the uterus and cervix. The without sacrificing the quality of
radioisotope is placed in the body care given
cavity, generally for 24 to 72 hours.
In an INTERSTITIAL THERAPY, the
S – hielding
radioisotope is placed in needles,
beads, seeds, ribbons, or catheters, Use lead shield during contact with
which are then implanted directly into client
the tumor
 Pregnant staff should not be
B. UNSEALED SOURCE – assigned to clients receiving
internal RT
The radioisotopes may be
administered intravenously, orally or by  The film badge should not be
instillation directly into the body cavity. shared, should not be worn other
than at work, & should be returned
 the radioisotope circulates through
according to the agency’s protocol
the client’s body. *
Staff members caring for the client with
PRINCIPLES OF RADIATION
internal RT should wear radiation
PROTECTION – DTS
dosimeter badge while in the client’s
 D – istance room.
 The greater the distance from the  If the client with cancer of the
radiation source, the less the cervix has radioisotope implant into
exposure dose of ionizing rays. the uterus, the following nursing
interventions should be
 Maintain a distance of at least 3
implemented.
feet when not performing nursing
procedures. 1. Client’s back is turned towards the
door.
 Performed in closed proximity such
as checking placement of the 2. Encourage the client to turn to sides
implant & performing nursing at regular intervals
procedures
3. The client should be on complete
T – ime bed rest.
 Limit contact with the client for 5 4. The client should be given enema
minutes each time, a total of 30 before the procedure.
minutes per 8-hour shift
5. The client should be given low fiber
 Organize care to limit the amount of diet to inhibit defecation during the
time spent in direct contact with procedure until the device is removed
the patient in 2-3 days.
6. The client should have a Foley the machine being operated, and
catheter in place during the procedure. the machine may move during the
therapy.
7. Have long forceps and lead container
readily available. 4. As a safety precaution for the
therapy personnel, you will remain
8. Foods are served on disposable
alone in the treatment room while the
plates and utensils.
machine is in operation.
9. Trash and linens are kept in the
5. The technologist will be right outside
client’s room and are not removed until
your room observing you through a
the client is ready for discharge.
window or by a closed – circuit TV. You
10. The client is also instructed to rinse may communicate.
the sink with copious amount of water
6. There is no residual radioactivity
after tooth brushing and to flush the
after radiation therapy. Safety
toilet several times after each use.
precautions are necessary only during
11. Anyone entering the room wears a the time you are actually receiving
new pair of booties each time to irradiation. You may resume normal
prevent tracking the radioisotope out activities of daily living.
into the hallway.
CLIENT EDUCATION ON SKIN CARE IN
12. Caregivers should wear gloves EXTERNAL RADIATION THERAPY
when handling body fluids
Skin Care within The Treatment Area
13. Any emesis (vomiting), especially includes the following:
that occurs shortly after ingestion of
 Keep your skin dry.
oral radioisotope, should be covered
with absorbent pads, and the radiation  Do not wash the treatment area
safety officer should be called until you are instructed to do so.
immediately. When permitted, wash the treated
skin gently with mild soap, rinse
TEACHING GUIDELINES REGARDING
well, and pat dry. Use warm water
EXTERNAL RADIATION THERAPY
or cool water, not hot water.
1. It is painless
 Do not remove the lines or ink
2. Lie very still on a special table while marks (markings) placed on your
the intervention is being given and skin
you may be placed in a special
 Avoid using powders, lotions,
position to maximize tumor
creams, alcohol and deodorants on
irradiation.
the treated skin.
3. Each treatment usually lasts for few
minutes. You may hear sounds of
 Wear loose – fitting clothing to  Do not apply ointments, powders or
avoid friction over the treatment lotion to the area. Cornstarch may
area. be used.
 Do not apply tape to the treatment  Do not apply heat; avoid direct
area if dressings are applied. sunshine or cold on the area.
 Shave with an electric razor. Do not  Use soft cotton fabrics for clothing.
use pre-shave or after-shave To prevent skin irritation.
lotions.
 Do not erase markings on the skin.
 Protect your skin from exposure to These serve as guide for areas of
direct sunlight, chlorinated irradiation.
swimming pools, and temperature
extremes*
2. INFECTION
 Consult your radiation therapist or
nurse about specific measures for  this is due to bone marrow
individual skin reactions. suppression
NURSING INTERVENTIONS FOR SIDE  NURSING INTERVENTIONS:
EFFECTS OF RADIATION THERAPY
 Monitor blood counts
1. SKIN REACTIONS weekly, especially WBC
 erythema, dry/moist  Good personal hygiene,
desquamation nutrition, adequate rest
 atrophy, telangiectasia,  Teach the client signs of
depigmentation, necrotic/ulcerative infection to report to
lesions. physician
 NURSING INTERVENTIONS:
 Observe for early signs of 3. HEMORRHAGE
skin reaction and report to
 Platelets are vulnerable to
the physician.
radiation.
 Keep area dry.
 NURSING INTERVENTIONS:
 Monitor platelet count
Depigmentation telangiectasia
 Avoid physical trauma or use
 Washing area with water, no soap of aspirin( ASA)
and pat dry (do not rub). Mild soap
 Teach signs of hemorrhage
is permitted.
to report (e.g., gum
bleeding, nose bleeding,
black stools)
8. Social isolation is also
 Monitor stool and skin for experienced by the client due to
signs of hemorrhage fear of contaminating others with
radiation.
 Use direct pressure over
injection sites until bleeding
stops.
4. FATIGUE
 result of high metabolic demands
for tissue repair and toxic waste
removal
 plenty of rest and good nutrition

5. WEIGHT LOSS
 anorexia, pain, and effect of cancer

CHEMOTHERAPY
6. STOMATITIS AND XEROSTOMIA
 The use of chemicals as a systemic
(DRY MOUTH)
therapy for cancer.
 Ulceration of oral mucous
 Antineoplastic agents are used in an
membrane occurs
attempt to destroy tumor cells by
 NURSING INTERVENTIONS: interfering with cellular functions,
including replication.
 Administers analgesics
before meals, as prescribed  Chemotherapy is used primarily to
treat systemic disease rather than
 Bland diet, avoid smoking
localized lesions that are amenable
and alcohol
to surgery or radiation.
 Good oral hygiene with
Chemotherapy may be combined
saline rinses every 2 hours
with surgery, radiation therapy, or
 Sugarless lemon drops or both:
mint to increase salivation
 to reduce tumor size preoperatively
7. Diarrhea, nausea and vomiting, (neoadjuvant),
headache, alopecia (hair loss) and
cystitis, may also occur.
 to destroy any remaining tumor cells  Mucous membrane, blood cells, hair
postoperatively (adjuvant), or follicles, skin cells are rapidly
dividing cells.
 to treat some forms of leukemia or
lymphoma (primary).  Side effects of chemotherapy tend to
occur in these structures.
 Has fraction cell – kill. Only a certain
 GOALS:
no. of cancer cells are killed with
 CURE each course of chemotherapy.
Therefore, chemotherapy must be
 CONTROL
given in a series.
 PALLIATION OF
 May be cell – cycle specific (CCS) or
MANIFESTATIONS
cell –cycle non-specific (CCNS).
 CCS chemotherapy may
 CHEMOTHERAPY is a systemic destroy cancer cells at
intervention. It is recommended specific stage of cell division.
when:
 CCNS chemotherapy may destroy
 disease is widespread cancer cells at any stage of cell
dIvision.
 risk of undetectable disease
is high Chemotherapy Drugs

 Tumor cannot be resected  Interfere with cancer cell’s ability to


and is resistant to RT divide and reproduce.

 The OBJECTIVE of CHEMOTHERAPY  A single drug or a combination of


drugs is used
 To destroy all malignant
tumor cells without excessive
destruction of normal cells
CHEMOTHERAPY HAS THE
FOLLOWING CHARACTERISTICS
 It affects both normal and cancer
cells.
 The rapidly dividing cells, both the
normal and cancer cells are
vulnerable to destruction by
chemotherapy by disrupting cell
function and division.
1. Oral Chemotherapy Medications
(Taken by Mouth)
 come in a variety of oral forms (pills,
tablets, capsules, liquid)
 Oral chemo medications
 Sub-lingual chemo medications.

2. Subcutaneous Injection of
ANTIMETABOLITES Chemotherapy Treatments
 Chemotherapy drugs that interfere  are commonly used for some types
with DNA and RNA growth. of biologic response modifiers and
chemotherapy support drugs.
 They are cell-cycle specific
 Ex: capecitabine, gemcitabine,
pemetrexed 3. Intra-Muscular Chemotherapy
Injections
ANTHRACYCLINES
 Intra-muscular injection is a popular
 Are anti-tumor antibiotics that
method for anti- nausea medications
interfere with enzymes necessary for
because it bypasses an already
DNA replication.
irritated stomach.
 They are cell-cycle non-specific
 Ex: bleomycin, doxorubicin,
4. Intravenous Chemotherapy
mitomycin-C
Treatments
 This is the most common method of
PLANT ALKALOIDS chemotherapy administration, since
most chemo drugs are easily
 Are derived from certain types of
absorbed through the blood stream.
plants found in nature, and inhibit or
prevent mitosis.  IV push chemo
 Cell-cycle specific  An infusion of chemo
 Ex: taxanes, docetaxel, paclitaxel  A continuous infusion of chemo
ROUTES OF ADMINISTRATION OF Intravenous medications are given
CHEMOTHERAPY directly into the blood stream
through a variety of methods.
a. An angiocatheter may be placed in a the skin and the muscle) on the
vein in the arm or hand and then scalp.
removed after the chemo  This procedure is used most
medication is given commonly in acute leukemias but
b. b. PICC line. Can be inserted and can be used in other situations as
used for six weeks to a few months well.
before it is discontinued.
c. Non-tunneled catheters. Non-
tunneled catheters are inserted 5. Intraperitoneal Chemotherapy
directly through the skin into the Treatments
jugular or subclavian vein and travel  can be given directly into the
through the vessel to the superior abdominal cavity.
vena cava vessel at entrance of the  is done for cancer in the intra
right atrium of the heart abdominal area, e.g., ovarian cancer.
d. Tunneled Catheters.
are placed through the skin in the 5. Intra-Arterial Chemotherapy
middle of the chest. They are Treatments
tunneled through the subcutaneous  Intra-arterial infusions enable major
tissue and inserted into the superior organs or tumor sites to receive
vena cava vessel at entrance of the maximal exposure with limited
right atrium of the heart. serum levels of medications.
e. Port-a-cath. 7. Intravesicular Chemotherapy
 The port-a-cath is placed under the Treatments
skin on the chest.
Intravesicular medications are given
4. Intraventricular/Intrathecal with the use of a urinary catheter
Chemotherapy Treatments directly into the bladder.

 is used when drugs need to reach  8. Intrapleural Chemotherapy


the cerebrospinal fluid (CSF), the Treatments
fluid that is in the brain and spinal Chemotherapy can be given into the
cord. pleural.
There are two ways chemotherapy  Intrapleural chemotherapy is used
can be given to the CSF: to control malignant pleural
1. Lumbar puncture (Intrathecal). effusions
Chemotherapy can be given through
a lumbar puncture (spinal tap).  Topical Chemotherapy Treatments
Some chemotherapy creams are applied
2. Ommaya reservoir
directly to the skin in certain cases of
(Intraventricular).
skin cancer.
 It is placed into the subcutaneous
tissue (the layer of tissue between
 The cream is then absorbed through 9. Contaminated needles and
the skin directly into the cancerous syringes must be disposed in a
lesion. The use of topical clearly marked special container,
preparations is very limited in cancer “leak – proof”, puncture – proof”
treatments 10. Dispose half – empty ampules,
CONTRAINDICATIONS TO vials, IV bottles by putting into
CHEMOTHERAPY plastic bag, seal and then into
1. INFECTION another plastic bag or box, clearly
2. RECENT SURGERY marked before placing for removal.
3. IMPAIRED RENAL/HEPATIC Label as “HAZARDOUS WASTE.”
FUNCTION 11. Hand washing should be done
4. RECENT RADIATION THERAPY before and after removal of gloves.
5. PREGNANCY 12. Only trained personnel should be
6. BONE MARROW DEPRESSION involved in use of drugs (preferably,
chemotherapy certified nurses).
SAFE HANDLING OF 13. Ideally, preparation of
CHEMOTHERAPEUTIC AGENTS chemotherapeutic drugs should be
1. Wear mask, eye shield, gloves and in laminar flow conditions with
back –closing gown. filtered air to prevent contamination
2. Skin contact with drug must be with microorganisms
washed immediately with soap and NURSING INTERVENTIONS FOR
water. Eyes must be flushed CHEMOTHERAPY SIDE -EFFECTS
immediately with copious amount of
water. NURSING INTERVENTIONS FOR
3. Sterile / alcohol – wet cotton CHEMOTHERAPY SIDE -EFFECTS
pledgets should be used, wrapped
around the neck of the ampule or 1. G.I. SYSTEM – nausea and vomiting,
vial when breaking and withdrawing diarrhea, constipation
the drug.  Administer antiemetic to relieve
4. Expel air bubbles on wet cotton. nausea and vomiting
 Replace fluid – electrolyte losses,
5. Vent vials to reduce internal low – fiber diet to relieve diarrhea
pressure after mixing.  Increase fluid intake and fibers in
6. Wipe external surface of syringes diet to prevent / relieve constipation
and IV bottles.
7. Avoid self - inoculation by needle 2. INTEGUMENTARY SYSTEM
stab.  PRURITUS, URTICARIA & SYSTEMIC
8. Clearly label the hanging IV bottle SIGNS
with “ANTINEOPLASTIC  Provide good skin care
CHEMOTHERAPY”  STOMATITIS (ORAL MUCOSITIS)
 Provide good oral hygiene
 Avoid hot and spicy food  Premature menopause or
amenorrhea
 ALOPECIA  Reassure that menstruation
 Reassure that it is temporary resumes after chemotherapy
 Encourage to wear wigs, hats
or head scarf ADVERSE REACTIONS TO
 SKIN PIGMENTATION CHEMOTHERAPY ARE AS FOLLOWS:
 Inform that it is temporary
 NAIL CHANGES 1. Hypersensitivity reaction
 Reassure that nails may grow a. Dyspnea
normally after chemotherapy b. Chest tightness or pain
c. Pruritus (itching)
3. HEMATOPOIETIC SYSTEM d. Urticaria (wheals)
 Anemia e. Tachycardia
 Provide frequent rest f. g. Anxiety
periods h. Agitation
 Neutropenia i. Inability to speak
 Protect from infection j. abdominal pain
 Avoid people with infection k. nausea
 Report fever, chills, l. hypotension
diaphoresis, heat, pain, m. cloudy mental status
erythema, or exudates on n. flushed appearance
any body surface o. cyanosis
 Thrombocytopenia
 Protect from trauma  If anaphylactic reaction occurs, the
 Avoid ASA following nursing interventions are
 Nadir - It is the time after implemented:
chemotherapy administration when a. Stop the drug administration
WBC or platelet count is at the b. Maintain IV access with 0.9%
lowest point. It occurs within 7 to 14 NS (NaCl)
days after drug administration. c. Keep an open airway.
d. Keep client in modified
4. GENITO – URINARY SYSTEM Trendelenburg position
 Hemorrhagic cystitis (supine with legs elevated at
 Provide 2-3 liters of fluids per 20-30’), unless
day contraindicated.
 Urine color changes
 Reassure that it is harmless

5. Reproductive system
2. Extravasation

 Vessicant chemotherapeutic agents


can cause or form a blister and cause
tissue destruction. Eg., Adriamycin
(Doxurubicin), Oncovin (Vincristine).
 Irritant drugs can produce venous
pain at the site and along the vein
 Pain, erythema, swelling and lack of
blood return indicate an
extravasation.

NURSING INTERVENTIONS FOR Nursing Management of


EXTRAVASATION include the following: Cancer
Maintaining Tissue Integrity
Some of the most frequently encountered
disturbances of tissue integrity include
stomatitis, skin and tissue reactions to
radiation therapy, alopecia, and malignant
skin lesions.
Managing Stomatitis
 Assess oral cavity daily.
 Instruct patient to report oral
burning, pain, areas of redness,
open lesions on the lips, pain
associated with swallowing, or
decreased tolerance to temperature
extremes of food.
 Encourage and assist in oral hygiene.
 For mild stomatitis, use normal advise that hair loss may occur on
saline mouth rinses and a soft body parts other than the head.
toothbrush or toothette, remove
 Explore potential impact of hair loss
dentures except for meals (make
on self-image, interpersonal
sure dentures fit properly), apply
relationships, and sexuality.
water-soluble lip lubricant, and avoid
foods that are spicy or hard to chew  Prevent or minimize hair loss
and those with extremes of
 Suggest ways to assist in coping with
temperature.
hair loss (eg, purchase wig or
 For severe stomatitis, obtain tissue hairpiece before hair loss; wear head
samples for culture and sensitivity coverings).
tests, assess gag reflex and ability to
 Explain that hair growth usually
chew and swallow
begins again once therapy is
 Help patient minimize discomfort by completed.
using prescribed topical anesthetic,
administering prescribed systemic
analgesics, and performing
appropriate mouth care.

Managing Malignant Skin Lesions


Managing Radiation-Associated Skin
 Carefully assess and cleanse the
Impairments
skin, reducing superficial bacteria,
 Provide careful skin care by avoiding controlling bleeding, reducing odor,
the use of soaps, cosmetics, protecting skin from pain and
perfumes, powders, lotions and further trauma, and relieving pain.
ointments, and deodorants.
 Assist and guide the patient and
 Instruct the patient to avoid rubbing family regarding care for these skin
or scratching the area, exposing the lesions at home; refer for home care
area to sunlight or cold weather, or as indicated.
wearing tight clothing over the area.
Promoting Nutrition
 If wet desquamation occurs, do not
 Teach the patient to avoid
disrupt any blisters that have
unpleasant sights, odors, and sounds
formed, report blistering, and use
in the environment during mealtime.
prescribed ointments
 Suggest foods that are preferred and
Addressing Alopecia
well tolerated by the patient,
 Discuss potential hair loss and preferably high-calorie and high-
regrowth with patient and family; protein foods.
 Encourage adequate fluid intake, but  Assure patient that you know that
limit fluids at mealtime. pain is real and will assist him or her
in reducing it.
 Suggest smaller, more frequent
meals.  Help patient and family play an
active role in managing pain.
 Promote relaxed, quiet environment
during mealtime with increased  Provide education and support to
social interaction as desired. correct fears and misconceptions
about opioid use.
 Encourage nutritional supplements
and high-protein foods between  Encourage strategies of pain relief
meals. that patient has used successfully in
previous pain experience.
 Encourage frequent oral hygiene and
provide pain relief measures to  Teach patient new strategies to
make meals more pleasant. relieve pain and discomfort:
distraction, imagery, relaxation,
 Provide control of nausea and
cutaneous stimulation, etc.
vomiting.
 Patients with cancer may have other
sources of pain, such as arthritis or
 For collaborative management, migraine headaches, that are
provide enteral tube feedings of unrelated to the underlying cancer
commercial liquid diets, elemental or its treatment.
diets, or blenderize foods as
prescribed.
 Administer appetite stimulants as
prescribed by physician.
 Encourage family and friends not to
nag or cajole patient about eating.
 Decrease anxiety by encouraging
verbalization of fears and concerns,
use of relaxation techniques, and
imagery at mealtime.
Relieving Pain
 Use a multidisciplinary team
approach to determine optimal
 The nurse assesses the patient for
management of pain for optimal
the source and site of pain as well as
quality of life.
those factors that influence the
patient’s perception and experience
of pain, such as fear and
apprehension, fatigue, anger, and
social isolation.
 Pain assessment scales are useful for
assessing the patient’s pain before
and after pain-relieving
interventions are instituted to assess
the effectiveness of interventions.
 The nurse assists the patient and
family to take an active role in
managing pain.
 The nurse provides education and
support to correct fears and
misconceptions about opioid use.
Inadequate pain management leads
to a diminished quality of life
characterized by distress, suffering,
anxiety, fear, immobility, isolation,
and depression.

Decreasing Fatigue
 Help patient and family to
understand that fatigue is usually an
expected and temporary side effect
of the cancer process and  Encourage continued participation in
treatments. activities and decision making.
 Help patient to rearrange daily
schedule and organize activities to
 Assist patient in self-care when
conserve energy expenditure
fatigue, lethargy, nausea, vomiting,
 Encourage patient and family to plan and other symptoms prevent
to reallocate responsibilities, such as independence.
childcare, cleaning, and preparing
 Assist patient in selecting and using
meals.
cosmetics, scarves, hair pieces, and
 Encourage adequate protein and clothing that increase his or her
calorie intake; assess for fluid and sense of attractiveness.
electrolyte disturbances.
 Encourage patient and partner to
 Encourage regular, light exercise, share concerns about altered
which may decrease fatigue and sexuality and sexual function and to
facilitate coping. explore alternatives to their usual
sexual expression.
 Encourage use of relaxation
techniques and mental imagery.  Refer patient to collaborating
specialists as needed.
 Address factors that contribute to
fatigue and implement Assisting in Grieving
pharmacologic and
 Encourage verbalization of fears,
nonpharmacologic strategies to
concerns, negative feelings, and
manage pain.
questions regarding disease,
 Administer blood products as treatment, and future implications.
prescribed.
 Encourage active participation of
patient or family in care and
treatment decisions.
Improving Body Image and Self-Esteem
 Visit family frequently to establish
and maintain relationships and
 Assess patient’s feelings about body physical closeness.
image and level of self-esteem.
Encourage patient to verbalize
concerns.  Involve spiritual advisor as desired
by the patient and family.
 Identify potential threats to patient’s
self-esteem  Allow for progression through the
grieving process at the individual
pace of the patient and family.
 Advise professional counseling as  Assess frequently for infection and
indicated for patient or family to inflammation throughout the course
alleviate pathologic grieving. of the disease.
 If patient enters the terminal phase  Prevent septicemia and septic shock,
of disease, assist patient and family or detect and report for prompt
to acknowledge and cope with their treatment.
reactions and feelings.
 Monitor for signs and symptoms of
 Maintain contact with the surviving septic shock
family members after death of the
 Instruct patient and family about
patient.
signs of septicemia, methods for
preventing infection, and actions to
take if infection or septicemia
Monitoring and Managing Potential
occurs.
Complications
Managing Infection Managing Bleeding and Hemorrhage
 Assess patient for evidence of  Monitor platelet count and assess
infection for bleeding
Report fever (≥38.3°C [101°F] or ≥38°C  Instruct patient and family about
[100.4°F] for greater than 1 hour), chills, ways to minimize bleeding
diaphoresis, swelling, heat, pain, erythema,
 Initiate measures to minimize
exudate on any body surfaces.
bleeding
 Discuss with patient and family
 When platelet count is less than
about placing patient in private
20,000/mm3, institute bed rest with
room if absolute WBC count is less
padded side rails, avoidance of
than 1,000/mm3 and the
strenuous activity, and platelet
importance of patient avoiding
transfusions as prescribed.
contact with people who have
known or recent infection or recent
vaccination.
 Instruct all personnel in careful hand
Promoting Home- and Community-
hygiene before and after entering
Based Care
room.
Teaching Patients Self-Care
 Avoid rectal or vaginal procedures
 Provide information needed by
(rectal temperatures, examinations,
patient and family to address the
suppositories, vaginal tampons) and
most immediate care needs likely to
intramuscular injections.
be encountered at home.
Managing Septic Shock
 Verbally review, and reinforce with  Assess adequacy of pain
written information, the side effects management and the effectiveness
of treatments and changes in the of other strategies to prevent or
patient’s status that should be manage side effects of treatment.
reported.
 Discuss strategies to deal with side
 Help coordinate patient care by
effects of treatment with patient and
maintaining close communication
family.
with all health care providers
 Identify learning needs on the basis involved in the patient’s care.
of the priorities identified by patient
 Make referrals and coordinate
and family as well as on the
available community resources.
complexity of home care.
 Instruct patient and family and
provide ongoing support that allows Nursing Management Related to Treatment
them to feel comfortable and Cancer Surgery
proficient in managing treatments at
home.
 Complete a thorough preoperative
 Refer for home care nursing to
assessment for all factors that may
provide care and support for
affect patients undergoing surgery.
patients receiving advanced
technical care.  Assist patient and family in dealing
with the possible changes and
 Provide follow-up visits and phone
outcomes resulting from surgery
calls to patient and family, and
evaluate patient progress and  Explain and clarify information the
ongoing needs. physician has provided about the
results of diagnostic testing and
surgical procedures, if asked.

Continuing Care
 Communicate frequently with the
physician and other health care
team members to ensure that the
 Refer patient for home care
information provided is consistent.
 Assess changes in the patient’s
 After surgery, assess patient’s
physical status and report relevant
responses to the surgery and
changes to the physician.
monitor for complications such as
infection, bleeding, hemorrhagic cystitis), and give constant
thrombophlebitis, wound attention to patient.
dehiscence, fluid and electrolyte  During the bone marrow infusions or
imbalance, and organ dysfunction. stem cell reinfusions, monitor vital
 Provide for patient comfort. signs and blood oxygen saturation,
assess for adverse effects
 Provide postoperative teaching that
addresses wound care, activity,
nutrition, and medications.  Because of the high risk for dying
 Initiate plans for discharge, follow- from sepsis and bleeding, support
up care, and treatment as early as patient with blood products and
possible to ensure continuity of care. hemopoietic growth factors and
protect from infection.
 Encourage patient and family to use
community resources such as the  Assess for early graft-versus-host
American Cancer Society for support disease (GVHD) effects on the skin,
and information. liver, and GI tract as well as GI
complications
Bone Marrow Transplantation
 Monitor for pulmonary
complications, such as pulmonary
 Before BMT, perform nutritional edema, and interstitial and other
assessments and extensive physical pneumonias, which often complicate
examinations and ensure that organ recovery after BMT.
function tests, as well as Provide ongoing psychosocial patient
psychological evaluations, are assessment, including the stressors affecting
completed as ordered. patients at each phase of the
 Ensure that patient’s social support transplantation experience.
systems and financial and insurance Hyperthermia
resources are evaluated.
 Explain to patient and family about
 Reinforce information for informed the procedure, its goals, and its
consent. effects.
 Provide patient teaching about the  Assess the patient for adverse
procedure and pre-transplantation effects, and make efforts to reduce
and post transplantation care. their occurrence and severity.

 Provide local skin care at the site of
During the treatment phase, closely
the implanted hyperthermic probes.
monitor for signs of acute toxicities (eg,
nausea, diarrhea, mucositis, and

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