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    Presentation On Penicillin Antibiotics

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    Penicillin is a widely used antibiotic that was the first discovered by Alexander Fleming in 1928. It works by inhibiting the synthesis of bacterial cell walls. There are several classifications of penicillin including natural penicillins, aminopenicillins, and antistaphylococcal penicillins. The mechanism of action involves interfering with the enzyme transpeptidase to prevent cross-linking of cell wall components. While commonly used to treat infections, penicillin can cause adverse reactions like rashes, diarrhea, and nausea. Bacteria can also develop resistance by decreasing drug penetration, altering binding proteins, or producing enzymes to destroy the beta-lactam ring.

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    Presentation On Penicillin Antibiotics

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    j9pnsj55j5
    3 views7 pages
    Penicillin is a widely used antibiotic that was the first discovered by Alexander Fleming in 1928. It works by inhibiting the synthesis of bacterial cell walls. There are several classifications of penicillin including natural penicillins, aminopenicillins, and antistaphylococcal penicillins. The mechanism of action involves interfering with the enzyme transpeptidase to prevent cross-linking of cell wall components. While commonly used to treat infections, penicillin can cause adverse reactions like rashes, diarrhea, and nausea. Bacteria can also develop resistance by decreasing drug penetration, altering binding proteins, or producing enzymes to destroy the beta-lactam ring.

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    Presentation on penicillin antibiotics

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    Penicillin is a widely used antibiotic that was the first discovered by Alexander Fleming in 1928. It works by inhibiting the synthesis of bacterial cell walls. There are several classifications of penicillin including natural penicillins, aminopenicillins, and antistaphylococcal penicillins. The mechanism of action involves interfering with the enzyme transpeptidase to prevent cross-linking of cell wall components. While commonly used to treat infections, penicillin can cause adverse reactions like rashes, diarrhea, and nausea. Bacteria can also develop resistance by decreasing drug penetration, altering binding proteins, or producing enzymes to destroy the beta-lactam ring.

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    3 views7 pages

    Presentation On Penicillin Antibiotics

    Uploaded by

    j9pnsj55j5
    Penicillin is a widely used antibiotic that was the first discovered by Alexander Fleming in 1928. It works by inhibiting the synthesis of bacterial cell walls. There are several classifications of penicillin including natural penicillins, aminopenicillins, and antistaphylococcal penicillins. The mechanism of action involves interfering with the enzyme transpeptidase to prevent cross-linking of cell wall components. While commonly used to treat infections, penicillin can cause adverse reactions like rashes, diarrhea, and nausea. Bacteria can also develop resistance by decreasing drug penetration, altering binding proteins, or producing enzymes to destroy the beta-lactam ring.

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    of 7

    PENICILLIN

    WIDE SPECTRUM ANTIBIOTIC

    BY SUYIMSENLA LEMTUR
    PHARM D 3RD YEAR
    WHAT IS PENICILLIN DRUG?
    Penicillin are a group of beta-lactam drugs
    that mainly works by inhibiting the synthesis
    of bacterial cell wall .
    They were the first antibiotics discovered by
    Alexander fleming in 1928
    They are taken from the fungus PENICILLIN
    NOTATUM
    CLASSIFICATION OF PENICILLIN:
    EXTENDED SPECTRUM
    NATURAL
    PENICILLIN
    PENICILLINS ANTISTAPHYLOCOCCAL
    PENICILLIN
    PENICILLIN V METHICILLIN
    PENICILLIN G CLOXACILLIN
    OXACILLIN
    NAFCILLIN AMINO UREIDOPENICLLINP
    CARBOXYPENICILLIN
    PENICILLIN
    PIPERACILLIN
    CARBENCILLIN
    AMPLICILLIN MEZLOCILLIN
    TICARCILLIN
    AMOXICILLIN AZLOCILLIN

    Instruments Equipment Protection and security


    MECHANISM OF ACTION:
    The synthesis of the Penicillin anitibiotics
    Bacterial cell is
    bacterial cell wall is inhibits the
    Beta-lactam antibiotics composed of
    completed by a Transpeptidase so that
    like Peniclllin works by peptidoglycan
    enzyme called cross linking does not
    interfering with the containing NAM and
    Transpeptidase for occur by binding to
    synthesis of cell wall NAG which makes the
    cross linking of NAM PENICILLIN-BINDING
    bacteria cell wall rigid PROTEIN
    and NAG

    NAM=N-Acetyl muramic acid


    NAG=N-Acetyl glucosamime

    Synthesis action takes


    Bacteria cell lysis
    place
    ADVERSE DRUG
    USES:
    REACTION:
    RASHES STREPTOCOCCAL
    DIARRHEA INFECTIONS
    NAUSEA STAPHYLOCOCCAL
    VOMITING INFECTIONS
    NEUROTOXICITY
    PNEUMOCOCCAL
    NEPHRITIS
    URTICARIA. INFECTIONS
    SYPHILLIS
    TETANUS
    DRUG RESISTANCE TO PENICILLIN:

    BACTERIA DEVELOP RESISTANCE DUE TO THE DECREASED ABILITY OF THE


    DRUG TO PENETRATE THE SIDE OF ACTION

    BACTERIA DEVELOP RESISTANCE DUE TO ALTERED PENICILLIN BINDING


    PROTEIN MAKING IT LESS AFFINITY FOR BETA LACTAMS

    BACTERIA DEVELOP RESISTANCE BECAUSE IT PRODUCES BETA-


    LACTAMASES WHICH DESTROYS BETA- LACTAM RINGS
    THANK YOU!

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