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In Vitro Antifungal Susceptibilities of Cryptococcus Neoformans From Pigeon Droppings, Cats, and Human Sources in Bangkok, Thailand
In Vitro Antifungal Susceptibilities of Cryptococcus Neoformans From Pigeon Droppings, Cats, and Human Sources in Bangkok, Thailand
2017, 47 : 131-132
1
Department of Veterinary Microbiology, 2Department of Veterinary Medicine, Faculty of Veterinary Science,
Chulalongkorn University, Bangkok 10330, Thailand
*Corresponding author: Nuvee.P@chula.ac.th
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Thai J Vet Med Suppl. 2017, 47 : 131-132
Table 1 MIC values among Cryptococcus neoformans isolates from pigeon droppings, cats, and humans.
Source of
Antifungal
isolation MIC50b MIC90c Mode
druga ≤0.12 0.25 0.5 1 2 4 8
(No. tested)
Pigeon droppings
AMB 4 14 1 0.5 0.5 0.5
(19)
CFG 19 4 4 4
FLZ 16 3 1 2 1
FC 17 2 1 2 1
MFG 19 4 4 4
VCZ 19 ≤0.12 ≤0.12 ≤0.12
Cats (8) AMB 2 6 1 1 1
CFG 1 7 4 4 4
FLZ 4 1 1 2 1 8 1
FC 8 1 1 1
MFG 1 7 8 8 4
VCZ 7 1 ≤0.12 ≤0.12 ≤0.12
Humans (2) AMB 2 1 1 1
CFG 2 4 4 4
FLZ 2 2 2 2
FC 2 1 1 1
MFG 2 4 4 2
VCZ 2 ≤0.12 ≤0.12 ≤0.12
a
AMB, amphotericin B; CFG, caspofungin; FLZ, fluconazole; FC, flucytosine; MFG, micafungin; VCZ,
voriconazole.
b
MIC50: MIC at which 50% of the isolates tested are inhibited.
c
MIC90: MIC at which 90% of the isolates tested are inhibited.
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