Nutrition Certificate

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FOUNDATIONAL CERTIFICATE
IN NUTRITION
FUNDAMENTALS OF NUTRITION SCIENCE

AKASH SEHRAWAT, HHP, CPT, PES

FABULOUS BODY INC

Copyright © 2022 by Fabulous Body, Inc. All rights reserved.

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This book or any portion thereof may not be reproduced or used in
any manner whatsoever—electronic or mechanical, including
photocopying, on the internet, recording or by any system of storing
and retrieving information — without the express written permission
of the publisher except for the use of brief quotations in a book
review.

Published by Fabulous Body, Inc

2228 Patterson Rd PMB #1900


Riverbank California 95367
United States

For more information about Fabulous Body please visit

www.fabulousbody.com

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Table of Contents
Disclaimer…………………………………………………………………………...……………………8

Preface………………………………………………………………………………………….…………..9

Module 1: Introduction To Nutrition…………………….....……….......13

Lecture 1: What Is Nutrition?........................................................................13


Lecture 2: Energy Balance: Energy Intake..................................................15

Lecture 3: Energy Balance: Energy Expenditure: BMR & TEF....……….18

Lecture 4: Energy Balance: Energy Expenditure: TEA & TDEE….……..22

Module 2: Macronutrients……………………………………..…………………….28

Lecture 1: Carbohydrates: Definition, Functions & Classification.…...28

Lecture 2: Glycemic Index……………………………………………………..……………...34

Lecture 3: Proteins: Definition, Functions & Classification…..…………...37

Lecture 4: Protein Intake: How Much Do We Need?................................41

Lecture 5: Fat: Definition, Functions & Classification………………………….46

Lecture 6: How to Figure Out Optimal Macronutrient Ratios……..…….54

Module 3: Micronutrients………..……………………………………………………59
Lecture 1: Fat-soluble Vitamins: Vitamin A & D………………….………………59

Lecture 2: Fat-soluble Vitamins: Vitamin E & K………………….…...………….66

Lecture 3: Water-soluble Vitamins: Vitamin B1, B2, B3, B5, B6..…….69

Lecture 4: Water-soluble Vitamins: Vitamin B7, B9, B12 & C…..........76

Lecture 5: Macro-minerals: Calcium, Phosphorus, Magnesium………...83

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Lecture 6: Macro-minerals: Sodium, Chloride, Potassium, Sulfur…….….89

Lecture 7: Micro-minerals: Iron, Zinc, Copper, Manganese…………………...97

Lecture 8: Micro-minerals: Selenium, Chromium, Iodine, Molybdenum,


Cobalt……………………………………………………………………………………………………..….104

Module 4: Special Compounds……………………………………..……………….112


Lecture 1: Fiber : Definition, Types & Health Benefits………………………….112

Lecture 2: Fiber : Optimal Fiber Intake, Foods High in Fiber………………..116

Lecture 3: Probiotics : Definition, Health Benefits & Top Foods…………..119

Lecture 4: Water : Health Benefits & Optimal Water Intake………………..125

Module 5: Nutrition Myths & Facts….……………………………………………131


Lecture 1: Myth #1: A Diet High in Fats is Bad for Your Health…………..131

Lecture 2: Myth #2: Saturated Fats Are Bad For Your Health……………..134

Lecture 3: Myth #3: Cooking in Vegetables Oils is Healthy…………………140

Lecture 4: Myth #4: Egg Yolks Raise Cholesterol Levels……………………..143

Lecture 5: Myth #5: Potatoes are Fattening…………………………………………...147

Lecture 6: Fact #1: Diets Fail | What You Need Is A Lifestyle Change…149

Lecture 7: Fact #2: Refined Carbohydrates and Added Sugar Are Bad For
You………………………………………………………………………………………………………………..152

Lecture 8: Fact #3: Supplements Can Never Completely Replace Your


Diet……………………………………………………………………………………………………………….155

Lecture 9: Fact #4: Eating More Fruits And Vegetables Is Good For Your
Health…………………………………………………………………………………………………………..157

Lecture 10: Fact #5: There Is No Perfect Diet For Everyone.………………..159

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Module 6: Superfoods….……………………………………………………………...160
Lecture 1: Superfoods: Fruits: An Introduction……………..…..…………….…160

Lecture 2: Superfoods: Fruits: Berries…………………………………...................164

Lecture 3: Superfoods: Fruits: Avocados………..…….……………………………..167

Lecture 4: Superfoods: Fruits: Other Superfruits……..………….................169

Lecture 5: Superfoods: Vegetables: Garlic, Onions & Ginger……………176

Lecture 6: Superfoods: Vegetables: Cruciferous Vegetables……………181

Lecture 7: Superfoods: Vegetables: Green Leafy Vegetables…………..184

Lecture 8: Superfoods: Vegetables: Other Vegetables………………………191

Lecture 9: Superfoods: Carbohydrates: Legumes…………………………..…..200

Lecture 10: Superfoods: Carbohydrates: Oats…………………………………….203

Lecture 11: Superfoods: Carbohydrates: Other Whole Grains………….206

Lecture 12: Superfoods: Proteins: Whole Eggs…………………………………..210

Lecture 13: Superfoods: Proteins: Grass-fed Dairy: Raw Milk,


Buttermilk………………………………………………………………………………………………...213

Lecture 14: Superfoods: Proteins: Grass-fed Dairy: Yogurt, Paneer…217

Lecture 15: Superfoods: Proteins: Grass-fed Meat & Wild-caught


Seafood……………………………………………………………………………………………………..220

Lecture 16: Superfoods: Fats: Healthy Oils…………………………………………..224

Lecture 17: Superfoods: Fats: Nuts………………………………………………………..229

Lecture 18: Superfoods: Fats: Seeds……………………………………………………..234

Lecture 19: Superfoods: Beverages: Green Tea…………………………………...238

Lecture 20: Superfoods: Beverages: Apple Cider Vinegar……………….…242

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Lecture 21: Superfoods: Beverages: Matcha Tea……………………………….245

Lecture 22: Superfoods: Beverages: Moringa Tea………………………………247

Lecture 23: Superfoods: Beverages: Coconut Water…………………………249

Lecture 24: Superfoods: Beverages: Kombucha………………………………...251

Lecture 25: Superfoods: Beverages: Lemon Juice………………………………253

Lecture 26: Superfoods: Condiments: Turmeric………………………………….256

Lecture 27: Superfoods: Condiments: Common Spices……………………..259

Lecture 28: Superfoods: Condiments: Raw Honey……………………………..263

Lecture 29: Superfoods: Condiments: Cinnamon………………………………..265

Lecture 30: Superfoods: Condiments: Sauerkraut………………………………268

Lecture 31: Superfoods: Condiments: Kimchi………………………………………271

Lecture 32: Superfoods: Condiments: Black Pepper…………………………..274

References………………………………………………………………………………………………..277

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Disclaimer

T he ideas, concepts, and opinions expressed in this book are

intended to be used for educational purposes only. The information


contained in this book should by no means be considered a substitute
for the advice of a qualified medical professional, who should always
be consulted before beginning any new diet, exercise, or another
health program.

This book is not meant to be used, nor should it be used, to diagnose


or treat any medical condition. For diagnosis or treatment of any
medical problem, consult your own physician.

The information in this book has been carefully researched, and all
efforts have been made to ensure accuracy. The publisher and author
assume no responsibility for any injuries suffered or damages or
losses incurred during or as a result of following the exercise and diet
program in this book.

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Preface

W e are facing an obesity epidemic where almost 2 billion

people worldwide are overweight and 650 million are obese.

This is hugely contributing to a significant increase in chronic diseases


like type-2 diabetes and heart-related conditions. These chronic
ailments are largely preventable by following a healthy diet
combined with an active lifestyle.

This Foundational Certificate in Nutrition will be of great interest to


all learners and healthcare professionals who would like to learn the
fundamentals of nutrition science.

It provides an in-depth look into macronutrients and micronutrients


and understands how they are essential for our bodies to grow and
remain healthy.

Module-1: ‘Introduction to Nutrition’ will start off by defining


nutrition and nutrients. You will understand the concept of Energy
Balance, BMR [Basal Metabolic Rate], TEF [Thermic Effect of Food],
TEA [Thermic Effect of Activity], and TDEE [Total Daily Energy
Expenditure]. I’ll help you figure out how to calculate all these with
the help of certain formulas.

Module-2: ‘Macronutrients’ will dive deep into three macronutrients


i.e. carbohydrates, proteins and fats. We will learn everything about
them, including their functions, classifications, types and

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requirements. The last lecture of this module will help you
understand how to determine macro ratios of any diet.

Module 3: ‘Micronutrients’ will discuss fat-soluble and water-soluble


vitamins, macro and micro minerals.

We will do an in-depth discussion on the important functions that


these micronutrients play in the human body, their best food sources,
and symptoms that may occur in case there is a deficiency of a
respective nutrient in our diet.

Along with visually pleasing lecture slides, you will find a voiceover
presentation which explains all the slides in detail plus you will find
the accompanying script (this master manual) in case you want to
read (helpful for people who are hearing impaired)

Module 4: ‘Special Compounds’ will discuss fiber, probiotics, and


water in detail.

Module 5: ‘Nutrition Myths & Facts’ . As the name suggests, in this


module I will bust the most common nutrition myths that are still
prevalent in today’s time. I’ll use solid science and some anecdotal
evidence to discuss them. Further the ‘Nutrition Facts’ will help you
deepen your understanding of various trending topics in the field of
Nutrition.

Module 6: ‘Superfoods’ will give you an idea of the best food items
that are nutrient dense in their respective categories like fruits,
vegetables, other carbohydrates, proteins, fats and more.

Once you have gone through the course material and are confident
enough please take the final exam and score above 50% to secure
yourself a CPD Certificate.

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Who is the course for?

A
- nyone who wants to learn how to eat healthily and

understand the fundamentals of nutritional science.

-Health & Fitness Professionals who want to help their clients with
general nutrition tips/guidelines.

By the end of this course, what


will you Learn?

-Understand what the Macronutrients are and the role they play in
our bodies.

-Understand the role Micronutrients, Fiber, Probiotics & Water play in


our bodies.

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-Understand Energy Balance. Figure out easy ways to determine
BMR, TDEE -Learn the Top Carbohydrates/Proteins/Fat sources and
figure out their estimated daily requirements & much more!

-Lastly, don’t forget to download the Resource Manual that will


provide you with links for additional reading relative to almost all
lecture topics discussed.

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M1: Introduction to Nutrition

L1: What is Nutrition?

L et's start with a formal definition of nutrition as provided in

Wikipedia:

"Nutrition is the science that interprets the nutrients and other


substances in food in relation to maintenance, growth, reproduction,
health and disease of an organism. It includes food intake, absorption,
assimilation, biosynthesis, catabolism, and excretion."

Another good definition of nutrition by Medicalnewtoday.com:

"Nutrition is the study of nutrients in food, how the body uses them,
and the relationship between diet, health, and disease."

As you can understand from the above definitions, nutrition is a vast


field with many topics and concepts.

Let's understand what we mean by the term nutrients.

Nutrients are substances that allow your body to make energy, build
and maintain tissues, and regulate bodily processes.

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Nutrients are mainly categorized into six categories:

-Carbohydrates
-Proteins
-Fats

These are the macronutrients that are required in large quantities.

-Vitamins
-Minerals

These are the micronutrients that are required in small quantities.

-Water

Water is also categorized as a nutrient even though it does not have


any calories because it is required in amounts that exceed the body's
ability to produce it.

There is a module titled: Special Compounds. Besides discussing


water in this module, we'll also discuss fiber and probiotics.

Let's discuss one of the most fundamental concepts in nutrition:

Energy balance.

Let's continue in the following lecture.

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M1: Introduction to Nutrition

L2: Energy Balance: Energy Intake

E nergy balance is the difference between energy intake

(calories in) and energy expenditure (calories out).

When the energy intake is more than energy expenditure, you gain
weight. The body stores the extra calories as fat.

When the energy intake is less than the energy expenditure, you lose
weight.

Let's define what a calorie is.

A Calorie is a unit of energy. The correct term for calorie is


'Kilocalorie.'

The kilocalorie is defined as the amount of heat needed to raise the


temperature of 1 kilogram of water from 0 to 1 degree Celsius.

To simplify things, almost every expert in the health and fitness


space uses the term 'Calorie' instead of 'Kilocalorie,' and I, too, feel it's
best to keep things simple.

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For information sake, let me briefly state the difference between a
calorie and a kilocalorie.

The calorie is defined as the amount of heat needed to raise the


temperature of 1 gram of water from 0 to 1 degree Celsius.

Therefore, 1000 calories = 1 Kilocalorie.

A calorie is also called a 'small calorie,' whereas a kilocalorie is called


a 'large calorie.'

Since we'll be using the term calorie so many times, it does not make
sense to use kilocalories every time, but it's important to know the
difference.

Food in the form of macronutrients, carbohydrates, proteins, and fats


have calories, whereas micronutrients like vitamins and minerals have
no calories.

1 Gram of Carbs= 4 calories


1 Gram of Protein= 4 calories
1 Gram of Fat= 9 calories

1 Gram of Alcohol = 7 calories

Our brains, our muscles — every cell in our body — require energy to
function in its optimal state.

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Junk/fast foods have calories in them as they are also made up of
carbohydrates, proteins, and fats, but those calories are termed
'empty' calories.

The term 'Empty' means these calories have very little or no


nutrients.

For example, pizza contains some nutrients like cheese which


contains calcium and protein.

However, other foods like candies, soft drinks, etc., contain only
empty calories and no nutrients.

Junk/Fast foods are refined and processed, resulting in a significant


loss in vitamins, minerals, fiber, or phytonutrients.

The carbohydrates in them are refined and processed; proteins are


denatured, and fats are unhealthy.

Furthermore, they are loaded with sugars (disguised under different


names) which create havoc inside our bodies and cause ill-health.

That's why most of your calories must come from unprocessed (or
minimally processed) foods.

In the next lecture, let's define energy expenditure, that is, calories
out.

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M1: Introduction to Nutrition

L3: Energy Balance: Energy Expenditure: BMR & TEF

S tudents, whenever you hear me talking about fat loss or

muscle-building concepts in my other courses, you will realize I talk a


lot about metabolism components like BMR, TEF, TEA, and TDEE.

These concepts are related to one's metabolism and activity burn and
comprise the energy expenditure, i.e., calories out.

Let's start with the first component of energy expenditure, which is


BMR.

Basal Metabolic Rate (BMR)

Basal metabolic rate (BMR) is the amount of energy expressed in


calories that a person needs to keep the body functioning at rest.

Just imagine lying down on a sofa the whole day doing nothing at all!

How lovely is that?

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This is just a hypothetical scenario where your body is burning
calories to sustain life, i.e., beating of your heart, energy for your
brain, breathing—essentially maintaining homeostasis.

BMR accounts for about 50 to 70% of daily energy expenditure.

Another name for BMR is Resting Metabolic Rate (RMR), which


stands for resting metabolic rate.

There are various formulas for estimating your BMR.

Let's look at the two most popular ones:

The Katch-McArdle Equation

BMR = 370 + (9.79 * lean mass in pounds)

The Mifflin-St Jeor Equation

For men: BMR = 10 x weight (kg) + 6.25 x height (cm) – 5 x age


(years) + 5
For women: BMR = 10 x weight (kg) + 6.25 x height (cm) – 5 x age
(years) – 161

If your head has started to spin from looking at these formulas, don't
worry. You are not alone.

I used to suck at math, so I always tried to find a shortcut.

I have a simple way out!

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All you have to do is take your body weight in pounds and multiply it
by 10!

And voila, you will get your BMR.

Although, there might be a slight difference in the result you will get
when using this formula compared with the equations provided.

So, let's say you are 170 pounds. If you know your weight in
kilograms, then simply multiply it by 2.2 to get your weight in
pounds.

Now, 170 pounds multiplied by 10 = 1700 calories. This is your BMR.

Your BMR number may vary depending on the equation you use, but
let me tell you, you cannot calculate an exact number, so don't even
try.

Estimates are fine.

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Thermic Effect of Food (TEF)

Let's now discuss the second component of energy expenditure—the


thermic effect of food (TEF).

The thermic effect of food is the caloric cost of digesting and


processing different macronutrients in your diet.

In simple words, when you eat food, a percentage of calories in the


food you eat is used to digest and absorb the rest of the food.

When you eat protein, 20 – 30% of the protein calories are burned
digesting it. This means a high protein diet will have a higher TEF.

When you eat carbohydrates, 5 –10% of carbohydrate calories are


burned digesting it, and with fats, only 0 – 3% of calories are burned
digesting it.

To put this in tangible terms, if you eat 200 calories of protein, your
body will use approximately 40 calories to digest it.

The most common estimate for the total thermic effect of food is
around 10% of your BMR.

Let's say your BMR is 1700 calories. Quite simply, your TEF would be
1700*10= 170 calories.

Let's discuss the thermic effect of activity in the next lecture.

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M1: Introduction to Nutrition

L4: Energy Balance: Energy Expenditure: TEA & TDEE

T hermic Effect of Activity (TEA)

TEA is the calories you burn through activity, i.e., your training and
workouts.

TEA is a function of your BMR, and the formula to calculate it is:


TEA= BMR * Activity Multiplier

Now let’s look at the different activity multipliers:


● Sedentary = BMR X 0.2
● Lightly active = BMR X 0.375
● Moderately active = BMR X 0.55
● Very active = BMR X 0.725
● Extra active = BMR X 0.9

Let's discuss each row in detail.

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Sedentary = BMR X 0.2

BMR is the number of calories you expend when lying down on the
sofa the whole day.

Let's say you start to move around your house, you go to your office
and perform other daily chores.

But you don't work out.

Because of this basic movement, there will be extra calorie burn in


addition to your BMR.

For this sedentary lifestyle, the thermic effect of activity can be


calculated by multiplying BMR by 0.2.

If your client's BMR is 1500 calories, their TEA = 1500*0.2= 300


calories with a sedentary lifestyle.

Lightly active = BMR X 0.375

You can put your clients in the category of lightly active if they do
some light movement 2 – 3 times a week.

These movements may include any of the following performed a few


times a week:

Walking for ~60 minutes

Or

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30 – 45 minutes of low-intensity cardio on a treadmill or a recumbent
bike

Or

30 – 45 minutes of yoga/Zumba or any sport where the intensity is


low to moderate

Moderately active = BMR X 0.55

Your client is moderately active if they do either of the following


activities:

Moderate-to high-intensity strength training 3 – 4 times a week


coupled with cardiovascular training 2 – 3 times a week.

The cardiovascular training can be either on a cardio machine or


through yoga, Zumba, or bodyweight/HIIT workouts.

Or

Play an outdoor sport like football, cricket, rugby, or tennis for 60 –


90 minutes 3 – 4 times a week.

Please note that your clients have desk jobs in both the lightly active
and moderately active categories.

This means that beyond these workouts, their step count is limited to
~5000 steps a day.

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Very active = BMR X 0.725

This category is reserved for people who are very active throughout
the day.

Their step count is easily over 10,000 steps and may go up to 15,000
steps per day at least five times a week.

In addition to their active lifestyle, they take part in either of the


following activities:

Moderate-to high-intensity strength training 5 – 6 times a week


coupled with cardiovascular training 2 – 3 times a week.

Or

Play an outdoor sport like football, cricket, rugby, or tennis for 60 –


90 minutes 5 – 6 times a week.

Extra active = BMR X 0.9

In the extra active category are athletes who work hard—real hard.
They take part in either of the following activities:

Moderate-to high-intensity strength training 7 – 10 times a week


coupled with cardiovascular training 3 – 5 times a week.

This means they often work out twice a day, a few times a week.

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Or

They are professional athletes/bodybuilders who spend 3 – 4 hours


every day playing their sport.

Most athletes also have a rigorous schedule that includes a few


strength training sessions combined with cardiovascular training.

Pro tip: Be conservative when selecting an activity multiplier for


yourself or your clients.

For example, I do moderate-to high-intensity weightlifting.

I combine it with 3 – 4 HIIT bodyweight sessions every week.

My step count averages 7,000 steps per day or around 50,000 steps
per week.

I put myself in a moderately active category.

TDEE Calculation

Now that we have figured out the three components of energy


expenditure, let's figure out TDEE.

We know that TDEE = BMR+TEF+TEA.

Let's calculate TDEE for a 170-pound person who is moderately


active.

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His BMR is 170*10= 1700 calories.

His TEF is 10% of 1700= 170 calories.

And his TEA= 935 calories (1.55)

Therefore, his TDEE= 1700 + 170 + 935 = 2,805 calories.

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M2: Macronutrients

L1: Carbohydrates: Definition, Functions &


Classification

W elcome to Module-2: Macronutrients.

As you may know, the three macronutrients are carbohydrates,


proteins, and fats.

This lecture will discuss carbohydrates, their function, and their


classification.

The concept of the glycemic index will be discussed in the following


lecture.

The next macronutrient that we shall discuss is proteins. We'll also


discuss their functions and their classification.

Daily protein requirement is a topic of confusion for many, and in


lecture 4, I'll provide you with a few protein ranges that you can
select based on the choice of your activity.

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The third macronutrient is fat.

Fat can be your best friend or your worst enemy.

It is easy to get confused about fats because some are good and
some are bad.

Lecture 5 is all about fats!

In Lecture 6, I'll provide you with Sally's example to help you


determine the macronutrient profile of a diet.

Now let's start with Carbohydrates.

Carbohydrates have become a very controversial topic these days.

One side of the panel, predominantly the paleo and ketogenic


advocates, says that we don't eat carbs because our ancestors didn't
eat them.

On the other side, experts suggest nothing wrong with carbs. Just go
ahead.

I'll try to answer this question for you towards the end of the next
lecture after discussing the glycemic index.

But first, let's begin with the definition of carbohydrates, their


function in our bodies, their classification, and their main food
sources.

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What are Carbohydrates?

Carbohydrates are molecules composed of carbon, hydrogen, and


oxygen atoms.

Since the ratio of hydrogen to oxygen atoms in carbohydrates is


usually the same as the water, that's the reason they are called
carbo+ hydrates as in watered carbons.

Functions of Carbohydrates

Carbohydrates provide 4 calories per gram. One of the most


important reasons why you should include healthy carbs in your diet
is because they provide us with fiber, both soluble and
insoluble.

I'll discuss fiber in detail in the module titled: Special Compounds.

Another vital function of including carbohydrates in your diet is its


protein-sparing effect.

Proteins are the main building blocks of the human body, and when
you eat enough carbs, then instead of protein, carbs are used for
energy, sparing the protein to do its essential job to build muscle
tissues and manufacture hormones. 1

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Carbohydrate Classification

Carbohydrates are classified as simple or complex.

Simple carbohydrates with just one sugar molecule are called


monosaccharides.

When two monosaccharides combine, they form a disaccharide.


Complex carbohydrates are many single monosaccharides linked
together.

Polysaccharides contain hundreds and even thousands of


monosaccharides linked together.

The other form of complex carbohydrates is fiber.

Common examples of monosaccharides are:

Glucose – blood sugar.


Fructose – found in fruits.
Galactose – found in milk products.

All types of carbohydrates eventually break down into glucose.

Examples of disaccharides are:

Sucrose: glucose + fructose


Lactose: glucose + galactose
Maltose: glucose + glucose

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Simple carbohydrates are found in fruits, honey, sweets, candies,
white bread, white rice, and sugar-sweetened beverages like soft
drinks, soda, fruit drinks, energy drinks, vitamin water, etc.

When you eat simple carbohydrates, the sugars in them get


absorbed quickly, causing a faster rise in blood sugar.

The pancreas has to release a lot of insulin to combat this sudden rise
of sugar in your blood.

When you eat a lot of refined carbs, like white rice, pasta, bagels, and
sugar-sweetened beverages over time, the cells in your body start to
resist insulin because so much is released every time you eat those
foods.

This leads to a condition called insulin resistance, which can lead to


type-2 diabetes!

Does this mean that the simple sugars in fruits are also bad? The
short answer is no!

Simple carbohydrates in fruits are surrounded by fiber, which slows


down gastric emptying of sugar.

In addition, fruits are loaded with vitamins, minerals, and other


nutrients good for health.

Calories in fruits are NOT empty calories.

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But the sugars in junk and fast foods, like candies, biscuits, cakes, and
sugar-sweetened beverages (SSBs), break down very quickly, as
there is little or no fiber in them.

Most junk and fast foods high in simple carbohydrates are devoid of
vitamins, minerals, and other nutrients, mainly empty calories.

Complex carbs provide a sustained source of energy.

Starch is a form of complex carbohydrates found in grains, legumes,


and beans.

The other form of complex carbohydrates is fiber. We'll discuss fiber


in detail in Module 5: Special Compounds.

Let's discuss the glycemic index in the next lecture.

33
M2: Macronutrients

L2: Glycemic Index

T he Glycemic Index (GI) is a measure that ranks carbohydrates

in foods according to how they affect blood glucose levels.

A numeric value from 1 – 100 is assigned to each carbohydrate-rich


food, with glucose (sugar) assigned a value of 100.

The GI system divides carbohydrate foods into three categories:

Low GI Foods: 55 or less


Medium GI Foods: 56 – 69
High GI Foods: 70+

Foods with a low GI value (55 or less) are more slowly digested and
absorbed, causing a slow rise in blood glucose. Less insulin is needed
to combat this gradual rise in blood sugar.

Some examples of low GI foods are whole milk, barley, oats, lentils,
berries, and beans.

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Foods with a medium GI value (56 – 69) cause a medium rise in blood
sugar, and a proportionate amount of insulin is released to combat
this rise in blood sugar.

Some examples of foods with medium GI are pasta, potatoes, and


brown rice.

Foods with a high GI value (>70) tend to get absorbed quickly,


causing a faster rise in blood sugar with more insulin released to
combat this sudden rise. 2

Examples of foods with a high GI value are white bread, white rice,
most breakfast cereals, candies, and cakes.

The Science of The Glycemic Index

A great analogy to explain the concept of GI is this: Imagine what


happens when it drizzles and when it pours.

Gentle rain or a drizzle allows a garden or rain harvest to utilize the


rainwater better. The water level does not rise, and there is no
flooding.

The same effect happens when you eat foods with a low GI value.

Sugar is digested and absorbed in the body slowly, leading to a


gradual increase in blood sugar, which the body can use better. 3, 4

35
On the contrary, think of a time when it pours. There are floods, and
most water is wasted and runs off to drains. Only a small percentage
gets utilized!

When you eat foods with high GI values, your body digests and
absorbs them quickly, causing a sudden rise in blood sugar levels,
and your pancreas must pump large quantities of insulin to combat it.

Insulin is a hormone that helps get the blood sugar (glucose) from
the blood to the cells. 5

Over time, when you eat more refined carbs and your body pumps
out a lot of insulin, the cells in your body start to resist it.

This increases the probability of becoming insulin resistant, leading to


type-2 diabetes.

So, as a thumb rule, eat low to medium carbohydrates on the GI


scale.

Let's discuss proteins in the next two lectures.

36
M2: Macronutrients

L3: Proteins: Definition, Functions & Classification

P rotein is an essential nutrient for our body. Proteins are the

building blocks of body tissue and can also serve as an alternate fuel
source when needed. 6

The human body uses protein for growth and maintenance. 7

Proteins also function as enzymes in membranes and as transport


carriers and hormones; their components serve as precursors for
nucleic acids, hormones, vitamins, and other integral molecules. 8, 9

One gram of protein contains four calories.

Protein and Amino Acids

Proteins are made up of amino acids, which are like the building
blocks of the human body.

When you eat proteins, your body breaks them down into its
constituent parts—amino acids.

37
Twenty different amino acids join together in various combinations to
make all proteins.

Our bodies can't make some of these amino acids; hence, they are
essential amino acids.

These nine essential amino acids we need to get from our diets.

Please note that histidine is the only essential amino acid that is
essential for infants!

Whereas eleven amino acids can be manufactured by the body and


termed non-essential amino acids, there is no need to get them from
your diet.

Protein Classification

In terms of a diet, protein sources are categorized according to how


many essential amino acids they provide. 10

A complete protein source provides all of the essential amino acids.


Complete proteins are often also referred to as high-quality proteins.

All animal-based food sources such as meat, poultry, fish, milk, eggs,
and cheese are complete protein sources.

An incomplete protein is low in one or more essential amino acids.


Most plant-based food sources such as grains, lentils, and rice are
incomplete proteins.

38
The only complete plant-based foods are soy, quinoa, and tofu.

Complementary proteins are two or more incomplete protein sources


that provide adequate amounts of all essential amino acids.

For example, rice contains low amounts of the essential amino acid
lysine and high doses of the essential amino acid methionine;
however, dry beans contain greater amounts of lysine and lesser
amounts of methionine.

Together, these two food sources can provide adequate amounts of


all the essential amino acids required by the human body.

So a point to remember is that you need a variety of plant-based


protein foods.

This ensures that your body gets all the essential amino acids as
most plant-based proteins are low in one or two essential amino
acids.

A vast and widespread myth that you may have come across is this:

Do I need to combine specific plant-based protein sources to ensure


that the given meal has all the amino acids?

The answer is No!

It's ok to eat a variety of plant-based protein foods at any point in


time during the day and not necessarily in the same meal.

39
With this thought in mind, let us understand in a lot of detail how
much protein you should eat every day from your diet.

Please note the protein requirement is different for everyone.

It's low for sedentary adults, and as you start to engage in physical
activities, the requirement increases.

Let's continue in the next lecture.

40
M2: Macronutrients

L4: Protein Intake: How Much We Need?

P rotein Requirement for Sedentary Individuals

The RDA, which stands for recommended daily allowance (average


daily intake level sufficient to meet the nutrient requirements of
nearly all 97-98% healthy people) for protein intake, is 0.8 grams per
kilogram of body weight.

But please note this intake is acceptable for people who live a
sedentary lifestyle and represents an intake level necessary to
replace losses and avert deficiency.

In simple words—to prevent malnutrition.11

However, this recommended intake is not enough for active people.

41
How much Protein Per Day for Active Individuals

Numerous studies indicate protein requirements for active individuals


are approximately double that of the RDA—at least 1.2
– 2.0 grams per kilogram of bodyweight. 12, 13

This range is recommended by:

The Academy of Nutrition and Dietetics


The American College of Sports Medicine

The International Society of Sports Nutrition also recommends a


similar (1.4—2g/kg) range. 14

Of course, there is a broad range and can be further subdivided based


on the choice of activity (intensity, duration, and type).

Individuals engaging in endurance exercise should ingest levels at


the lower end of this range, or 1.4 grams/kg/day.

In this case, the person should consume about 70 (bodyweight in


kilos) x 1.4 (grams of protein) = 98 grams of protein per day.

Individuals engaging in intermittent activities, such as football, rugby,


etc., should ingest levels in the middle of this range, or 1.7
42 grams/kg/day.

In this case, the person should consume about 70 (bodyweight in


kilos) x 1.7 (grams of protein) = 119 grams of protein per day.

42
People engaging in strength/power exercises, such as heavyweight
training, should ingest levels at the upper end of this range, or 2
grams/kg/day.

In this case, the person should consume about 70 (body weight in


kilos) x 2 (grams of protein) = 140 grams of protein per day.

How Much Protein Per Day | Maximum intake

Based on numerous studies and research, one can conclude that for
active individuals partaking in physical activities ranging from sports
to weight training, the optimal protein range is between 1.2 to 2g/kg.

So the question that demands attention here is this:

Is there any additional benefit of ingesting more than 2g/kg of body


weight of protein per day?

The additional benefit could be either more muscle gain or superior


fat loss.

The top guns performed a systematic review, meta-analysis, and


meta-regression in this industry like Alan Aragon, Menno
Henselmans, Brad Schoenfeld et al. 15

And they concluded that protein intake at amounts higher than


~1.6g/kg/day does not further contribute to RET (Resistance exercise
training)-induced gains in FFM (fat-free mass).

43
A 2006 study by Hoffman et al. concluded that protein intake above
2g/kg/day did not produce any significant strength or lean
mass gains. 16

So if you are a 70kg individual, you don't need more than 112g
(70*1.6) of daily protein for maximal muscle gains.

More protein, however, will not result in extra muscle gains!

Protein intake above 2 grams/kg/day is only advised in special cases,


such as very high energy intake.

Suppose an individual is an athlete and has a caloric requirement of


4,000 calories.

In that case, calculating his protein requirement at a modest level of


only 12 – 15 percent of the total calories gives us about 150 grams
(15 percent of 4,000 calories = 600/4 = 150 grams), which is 2.14
grams/kg/day.

However, these cases are sporadic, and the lower amounts described
above should be sufficient for most recreational athletes.

As explained above, RDA guidelines for protein intake are less than
the amount required for active individuals and should thus be
adjusted according to one's type of activity.

If you indulge in low-to-moderate activity, target at least the lower


end of the range, i.e., 1.2 to 1.4g/kg/day.

44
If you participate in moderate-to-high intensity activities such as
weight training, Crossfit, HIIT, powerlifting, etc., consume between
(1.5 to 2)g/kg/day.

Aim to get your protein from various food sources to get all the
essential amino acids, especially if you are a vegetarian/vegan.

Let's move on to the third macronutrient that is fat.

45
M2: Macronutrients

L5: Fats: Definition, Functions & Classification

F ats can be your best friend or your worst enemy.

It is easy to get confused about fats because some are good and
some are bad. This lecture will answer the following fat-related
questions:

What is fat?
What are the functions of fat?
What are the different types of fat?
Which fats are good and which are bad?

Fats are made of collections of molecules called triglycerides.


If this collection is liquid at room temperature, it can be called an oil;
if it's solid, it is referred to as fat.

A triglyceride is formed from three fatty acids attached to a glycerol


molecule.

46
Functions of Fat

Fats are the largest and the cleanest energy source, and they provide
9 calories per gram, more than double that of proteins and
carbohydrates.

They are essential for growth, development, and cell functions.

They also help maintain the body's core temperature and help absorb
fat-soluble vitamins like A, D, E, K. 17, 18

Types of Fats and Oils

Fats can be categorized as saturated fats and unsaturated fats.

Unsaturated fats are subdivided into monounsaturated fats and


polyunsaturated fats.

Polyunsaturated fats are further divided into omega-6 and omega-3.

All fats and oils, regardless of whether they are of vegetable or


animal origin, are some combination of saturated fatty acids,
monounsaturated fatty acids, and polyunsaturated fatty acids.

In general, animal fats such as butter, lard, and tallow contain about
40 – 60 percent saturated fat and are solid at room temperature.

47
Good Fats

Good fats, as the name suggests, are good for your health. I
encourage you to include three types of fats in your diet daily.

Let's start with the type of fat everyone loves: Monounsaturated Fats.

Monounsaturated Fats

Monounsaturated fats (abbreviated MUFAs) contain one double bond


between two carbon atoms. Mono means one.

The most common type of monounsaturated fatty acid is oleic acid.

MUFAs are mainly found in plant foods. The most common sources of
MUFAs are olive oil, avocados, almonds, cashews, peanuts, and
pumpkin seeds.

The benefits of monounsaturated fatty acids are well documented


and unlike saturated fats, not controversial.

Almost every expert agrees that adding olive oil (which has the
highest MUFAs) benefits heart health by increasing HDL, and studies
have linked MUFAs with lowered blood pressure!

More studies link MUFAs with decreased inflammation, which


reduces the risk of chronic diseases. 19, 20, 21

48
Don't we all wish that nutrition science be as straightforward as
monounsaturated fatty acids, where most studies on these fats
conclude a positive health outcome?

However, the next type of fat we shall discuss is precisely the


opposite, i.e., controversial.

Saturated Fats

Contrary to conventional wisdom, which demonizes saturated fats, I


strongly feel it is one of the healthiest fats one can consume.

Saturated fats contain single covalent bonds between the carbon


atoms of fatty acids.

Each carbon atom is bonded with a maximum number of hydrogen


atoms in the molecule; hence the term saturated.

In Module 4, 5 Nutrition myths, I have discussed saturated fats in


detail.

Omega-3

Omega-3's are found within the cell membranes of trillions of human


cells and play a critical role in the body's most fundamental
processes.

Omega-3 fatty acids help reduce inflammation, while most omega-6


fatty acids tend to promote inflammation. 22, 23

49
Omega-3 fatty acids are highly concentrated in the brain and appear
essential for cognitive and behavioral functions, such as brain
performance and memory.24

More than 50 percent of the brain are lipids, with DHA being the
most predominant of all structural fatty acids in your brain.25

So clearly, optimal consumption of omega-3 fatty acids is vital for


good health.

I have linked up an in-depth article on Omega-3. In that article, you


can learn about daily omega-3 intake, both animal and plant-based
foods rich in Omega-3.

Please find the article link in the resource manual.

Bad fats

An omega-6 fatty acid is a type of polyunsaturated fatty acid.


The most common omega-6 is linoleic acid, an essential amino acid
that the body cannot manufacture on its own.

Even though Omega-6 polyunsaturated fats are essential to us, they


may pose health issues when eaten in excess.

It's crucial to maintain a ratio of omega-6 to omega-3 of 1-1 to a


maximum of 4:1 for optimal health.

Unfortunately, today's modern diet has a highly skewed ratio of 20:1


or more.

50
The detailed discussion of this ratio is outside the scope of this
fundamental course.

To maintain a ratio of omega-6 to omega-3 of 1-1 to a maximum of


4:1, you must limit your intake of omega-6 polyunsaturated fatty
acids (PUFA's). The primary source of omega-6 is vegetable oils.

Soybean oil is the most commonly used vegetable oil around the
world.

The other types of vegetable oils are sunflower, cottonseed, sesame,


canola, rice bran, grapeseed, and so forth.

In the final lecture of this module, I will provide you with a strategy
that can act as a starting point for any laymen to figure out their
optimal macronutrient ratio in their diets.

Trans Fat

Trans fats are created when polyunsaturated vegetable oils are


heated in the presence of hydrogen gas to semi-solidify them.

Trans fats are used abundantly in processed foods because they


improve taste, increase shelf life, and have a less greasy feel.

Consumption of trans fat triggers chronic inflammation and increases


the risk of coronary heart disease. 26

It can cause insulin resistance and type-2 diabetes.

51
In 2015, the FDA placed a ban on products containing 'Partially
Hydrogenated Oils,' the primary source of trans fat in the food supply,
and considered them no longer "Generally Recognized as Safe." 27

Despite the ban, it can be challenging to avoid trans fats if you


consume processed foods frequently.

In the United States, food manufacturers can label their packaged


foods as trans-fat-free as long as there are fewer than 0.5g of these
fats per serving.

Even this small amount can add up, especially if you often eat
processed, junk, and fast foods!

Some of the common foods that contain trans fats are:

Margarine

Bakery Products: Cakes, pastries, doughnuts, and biscuits.

Fried Foods: French fries, fried noodles. Indian fried foods like
pakoras, samosas.

Any foods that are fried in vegetable oils. If vegetable oils are
reheated (which they are in most eateries), the trans-fat content
increases.

Chips, frozen pizzas, vegetable shortening, non-dairy creamers are


other processed foods that contain trans fat.

52
Just look for the phrase 'partially hydrogenated oils.’

The bottom line is trans fat plays havoc with your health. It's difficult
to total up just how many grams of trans fat you consume, especially
if you eat out regularly.

My recommendation is to significantly cut down your consumption of


bakery and fried foods.

Be a health-conscious individual and check the nutrition labels and


not what the food marketers want you to believe falsely.

53
M2: Macronutrients

L 6: Optimal Macronutrient Ratios

L et's say you have a client, and her name is Sally. She is 35 years

of age and weighs 140 lbs.

She desires to gain a few pounds of lean muscles in the coming


months. You recommend her heavy weight lifting sessions a few
times a week.

Based on the information we learned in the protein section, you


recommend a high protein intake that equates to 1.8g/kg of BW.

Sally's protein intake comes out to be: 1.8* 63.6kg (140)= 115g
(rounded off)

She has also been recommended a diet of 1500 calories.

115 g of protein provides 460 calories (115*4).

460 calories out of 1500 calories will be 30% (rounded off).

54
Therefore Sally is asked to eat 30% of her total calories from protein
which comes out to 115g per day.

After protein, I would recommend you move on to the fat calculations.

I recommend a fat intake of at least 25% of total calorie intake.

The fat percentage can even go up to 80% if your clients prefer a


standard ketogenic diet.

However, for most diets, the percentage of calories from dietary fats
is between 25 to 40%.

Again this range will vary on your client's food choices which are
intrinsically linked with their ethnic background.

The details of the macro splits for different diets and cuisines
worldwide are a vast topic that I have covered in my course:
Foundational Certificate in Diet Planning.

As per Sally's dietary preference, her average fat intake comes out to
be 30% of her total calorie intake.

To calculate this is easy. 30% of 1500 calories is 450 calories. 1g of


fat is 9 calories.

Therefore 450 calories/9= 50g of fats.

The healthy fat calories can come from nuts, seeds, egg yolk, whole
dairy like milk, yogurt, and coconut oil/ghee.

55
To summarize so far:

Protein intake: 30% 115g


Fat Intake: 30% 50g

The remaining calories will come from carbohydrates which will be


40% of the total calorie intake.

The calories will mainly come from complex carbs like mashed
potatoes, sweet potatoes, brown rice, steel-cut oats, dairy,
whole-grain bread, etc.

40% of 1500 calories is 600 calories which comes to 150g of carbs.

Putting everything together, here is the macro profile for Sally:

Sally PROTEIN FATS CARBS

1500 30% 30% 40%


CALORIE
S

GRAMS 112.5G 50G 150G

458 450 600


calories calories calories

56
Here's another macro splittable for a person who weighs 75kg (165
lbs) with a daily caloric requirement of 2000 calories.

% OF TOTAL CALORIES LOW (4 – MODERATE HIGH


20%) (20 – 40%) (40% +)

CARBS (in grams) 20 – 100 100 – 200 200 +

% IN RELATION TO THE LOW (9 – MODERATE HIGH


TOTAL CALORIES 20%) (20 – 40%) (40% +)

FAT (in grams) 20 – 45 45 – 88 88 +

GRAMS PER KG OF LOW (0.5 MODERATE HIGH (2


BODYWEIGHT – 0.8) (0.8 – 2) +)

PROTEIN (in grams) 37.5 – 75 75 – 150 150 +

A low-carb diet will range between 4 to 20% of 2000 calories.

In terms of grams, it would equate to about 20-100 grams of carbs


eaten per day.

Consuming less than 100g of carbohydrates is not an easy task


considering there are carbs in literally every processed food item,
often disguised under various names.

57
A Standard Ketogenic diet has no more than 20g of carbs or less.

A moderate carb diet will be between 100-200g.

Based on my 15+ years of experience in the health & fitness industry,


most people do very well on a moderate carb diet.

A diet containing more than 200g of carbs can be labeled as a


high-carb diet.

My strong recommendation is to include at least 25% of calories from


healthy fat sources when it comes to fat intake.

You can go up to as high as 40%. This obviously will depend on your


food choices and dietary preferences.

A Keto warrior will eat at least 70% of his calories from fat.

Just make sure that the calories from healthy fats should not fall
below 20%.

If you can learn and imbibe just this one thing from this course: that
healthy fats are indeed very good for you, I will consider the time
spent on this course a victory.

Seriously students, eat more fats to burn fat.

58
When it comes to proteins, remember that they are always calculated
by taking one's body weight into account.

The least one should go for is 1.2g/kg of BW, and ideally, one should
stay in the range of 1.2 to 2g/kg of bodyweight.

This lecture marks the end of our discussion of macronutrients.

Let's now look into micronutrients.

59
M3: Micronutrients

L1: Fat-Soluble Vitamins: A & D

H i students, welcome to Module 3: Micronutrients.

I'll start by discussing vitamins, followed by minerals.

Vitamins

Vitamins are organic compounds that are needed in small quantities


to sustain life. Most vitamin needs come from food as the body
cannot manufacture them.

There are 13 known vitamins, out of which four are fat-soluble, and
nine are water-soluble.

Fat-Soluble Vitamins are A, E, D & K.

Water-soluble are Vitamin B1, B2, B3, B5, B6, B7, B9, B12, and
Vitamin C.

60
Fat-Soluble Vitamins

Fat-soluble vitamins are stored in the fatty tissues of the body


and the liver. They can stay in the body for days and sometimes even
months.

Vitamin A

Vitamin A is a group of organic compounds that the human body


needs in minimal amounts. The body cannot manufacture it, and
therefore it has to be included in our diet.

Two forms of vitamin A available in the human diet are preformed


vitamin A found in animal foods and provitamin A found in plant
foods.

The most important provitamin A is beta-carotene. 28

Vitamin A Functions

Vitamin A plays many roles in our bodies. It regulates the immune


system plays a role in bone & tooth development and reproduction.

It is also vital for hair growth and essential for maintaining the
light-sensing cells in the eye.

61
Vitamin A Food Sources

Preformed vitamin A is abundantly available in animal products like


milk, eggs, chicken, liver, and fish.

Plant-based foods like carrots, sweet potatoes, and green leafy


vegetables have provitamin A.

Vitamin A Deficiency

Vitamin A deficiency is a leading cause of preventable blindness in


children worldwide. About a quarter to half a million children become
blind every year due to vitamin A deficiency.

The most common symptom of vitamin A deficiency is xerophthalmia.


29, 30

Children in Africa and South Asia are the most affected, and what is
unfortunate is that half of the children who become blind die
within a year of losing their sight. 31, 32, 33

Vitamin A deficiency is rare in most developed nations.

62
Vitamin D

Vitamin D, also known as calciferol, is a fat-soluble vitamin, which


means it can be stored in the body for a long time, just like vitamins
A, E, and K.

When exposed to sunlight, your skin produces vitamin D3


(cholecalciferol) and sends it to your liver.

From there, your liver changes it to a substance called 25(OH)D


(calcifediol). It then gets converted to 1,25(OH)2D (calcitriol), mainly
in the kidneys.

Calcitriol is the active steroid form of Vitamin D. The active form of


Vitamin D travels through the body, affecting almost every cell.

Functions of Vitamin D

One of the most vital functions of vitamin D is regulating the


absorption of calcium and phosphorus, which is essential for the
normal growth and development of bones and teeth. ​34, 35

There is also strong evidence for a protective effect of Vitamin D,


not only against several types of cancer but also against multiple
sclerosis and type 1 diabetes mellitus. 36

63
Two Ways to Get More Vitamin D

Sun, the best way to get adequate Vitamin D is through moderate


exposure to the sun during appropriate times.

If possible, expose at least your arms, legs, and back for 15 to 20


minutes two or three times a week.

After twenty minutes, you can put sunscreen on to prevent excessive


sun exposure, which may cause premature aging and increase cancer
risk.

If you work a night shift or live in Canada or Iceland, where there is no


sun most of the year, taking a vitamin D supplement can help ensure
that you get enough of this essential vitamin.

Remember that Vitamin D is fat-soluble, so it is possible to overdose,


as it can accumulate over time and potentially become toxic. Toxicity
is extremely rare, however.

Vitamin D Food Sources

It's close to impossible to get enough Vitamin D from food.


For example, 100 grams of salmon has about 500 IU, and a whole
egg has about 50 IU.

To be in the optimal range (40ng/ml—65ng/ ml), you will need at


least a few thousand IU daily.

64
Vitamin D Deficiency

Unlike other vitamins, vitamin D deficiency has become a widespread


issue worldwide as not many people are exposing themselves to the
sun.

Low levels of vitamin D in the blood may lead to weak bones.

In children, vitamin D deficiency manifests as rickets, a​disease


characterized by a failure of bone tissue to become properly
mineralized, resulting in soft bones and skeletal deformities. 37

I have written a very detailed article on Vitamin D on


fabulousbody.com. You can find the link in the Resource manual. 38

Let's discuss vitamin E & K in the next lecture.

65
M3: Micronutrients

L2: Fat-Soluble Vitamins: E & K

V itamin E is a group of related compounds divided into

tocopherols and tocotrienols. Alpha-tocopherol is the most common


type. It makes up 90% of the vitamin E in the blood.

Functions of Vitamin E

Vitamin E's primary role is to act as an antioxidant, preventing


oxidative stress and protecting your cell membranes from free
radicals. 39,
​ 40

Other nutrients such as vitamin C, vitamin B3, and selenium enhance


vitamin E's antioxidant properties.

In high amounts, vitamin E also acts as a blood thinner, reducing


blood clot ability.

Vitamin E Food Sources

The highest concentration of Vitamin E is mainly found in plant-based


foods.

66
The richest source of vitamin E are nuts, oils, and seeds. It is also
abundantly available in green leafy vegetables.

Vitamin E deficiency

Vitamin E deficiency is uncommon and is never detected in otherwise


healthy people.

It often happens in diseases that impair the absorption of fat or


vitamin E from food, such as cystic fibrosis and liver disease.

Vitamin E deficiency symptoms include muscle weakness, walking


difficulties, tremors, vision problems, poor immune function, and
numbness.

Vitamin K

Vitamin K is a fat-soluble vitamin that belongs to the family of


compounds, including phylloquinone (vitamin K1) and a series of
menaquinones (vitamin K2).

The main dietary forms are vitamin K1 (phylloquinone), found in plant


foods, and vitamin K2(menaquinones), found in animal-derived foods
and fermented soy products.

Functions of Vitamin K

Vitamin K plays an essential role in blood clotting. In fact, the "K"


stands for "koagulation," the Danish word for coagulation, which
means clotting. 41

67
Other functions of vitamin K include supporting bone health and
helping prevent the calcification of blood vessels, potentially reducing
the risk of heart disease.

Vitamin K Food Sources

The best dietary sources of vitamin K1 (phylloquinone) are leafy


green vegetables like spinach and kale.

Vitamin K2 (menaquinone) is mainly found in animal-sourced foods


fermented soy products.

Vitamin K Deficiency

Your blood wouldn't clot without vitamin K, and even a tiny wound
could cause unstoppable bleeding.

Fortunately, vitamin K deficiency is rare since the body only needs


small amounts to maintain blood clotting.

Low levels of vitamin K have also been linked with reduced bone
density and increased risk of fractures in women. ​42, 43, 44

There are no known side effects of excessive intake of dietary vitamin


K.

This is the end of the discussion of fat-soluble vitamins. Let's move


on to water-soluble vitamins starting with the next lecture.

68
M3: Micronutrients
L3: Water-Soluble Vitamins: B1, B2, B3, B5, B6

L et's start by discussing the B Vitamins first.

Vitamin B1

Vitamin B1 is a water-soluble vitamin. It is also known as thiamin.

Humans can store tiny amounts of thiamin in the liver, and therefore a
continued supply of this essential vitamin is required from our diet.

Functions of Vitamin B1

Vitamin B1 is an essential cofactor in the conversion of carbohydrates


into glucose.

Vitamin B1 performs its co-enzymatic functions for the adequate


energy supply to nucleic acids, neurotransmitters, and myelin.

Hence, it helps in the development and functioning of the nervous


system.

69
Vitamin B1 Food Sources

Rice lovers will be happy to know that rice has the highest source of
vitamin B1, providing more than the RDA per half-cup!

However, brown rice has a high concentration of this vital vitamin


unless the white rice is fortified with it.

It is also not uncommon to see cereals and bread fortified with


thiamin. Other sources of vitamin B1 are meat and fish like pork and
trout. Black beans are also rich in this vitamin.

It's important to note that a significant amount of thiamine is lost


when cooking water is thrown out.

Overall, heating food also reduces the thiamine content. This would
imply that it's best to steam your rice instead of boiling it. 45

At the same time, try not to overheat your food as it results in losing
this critical vitamin.

Vitamin B1 Deficiency

Thiamin deficiency is rare in the developed world. However, thiamin


deficiency's leading cause is low absorption or higher excretion rates
than normal.

This can be due to the use of certain medication, or alcohol


dependence, as alcohol impairs the body's ability to absorb thiamin.

70
Some early symptoms of thiamin deficiency are short-term memory
loss, muscle weakness, anorexia, etc. 46

The most common disease of thiamin deficiency is beriberi. Beriberi


causes impaired sensory, motor, and reflex functions. Therapeutic
doses of vitamin B1 can help overcome beriberi. 47

Vitamin B2

Vitamin B2, also known as riboflavin, is a water-soluble vitamin.

Our bodies can only store minimal water-soluble vitamins, usually in


the liver, heart, and kidneys, and the excess is excreted via urine.

Functions of Vitamin B2

Vitamin B2 is responsible for maintaining healthy blood cells. It helps


in boosting energy, protecting skin and eye health.

A point to note is that literally, all B vitamins help extract energy from
the food you eat into usable energy in the form of ATP.

Vitamin B2 Food Sources

Eggs, milk, and organ meats have the highest content of vitamin B2.
Spinach, almonds, mushrooms are some plant-based sources of this
vitamin.

Like vitamin B1, B2 is water-soluble and is lost in the cooking water.


To minimize loss, it's best to steam rice and not overcook your food.

71
Vitamin B2 Deficiency

The deficiency of vitamin B2 is extremely rare. But if manifested, it


may cause fatigue nerve damage and result in slow metabolism. 48

Vitamin B3

Vitamin B3, also known as niacin, is one of the B complex family's


water-soluble vitamins.

Functions of Vitamin B3

Vitamin B3 is essential for maintaining a healthy cardiovascular


system, especially balancing blood cholesterol levels. Niacin also
helps with brain function and healthy skin formation.

Vitamin B3 Food Sources

Niacin is present in both animal and plant foods in adequate


amounts.

Top animal foods rich in niacin are beef liver, chicken breast, turkey
breast, salmon, tuna, pork, beef, etc.

Top plant-based foods rich in niacin are brown rice, peanuts,


potatoes, seeds, etc.

72
Vitamin B3 Deficiency

Niacin deficiency is rare. Although when it happens, it can result in


skin rashes, diarrhea, or dementia. 49, 50

Vitamin B5

Vitamin B5, also known as pantothenic acid, is an essential


water-soluble vitamin.

Functions of Vitamin B5

Vitamin B5 helps break down food into energy. It helps manage


cholesterol levels by increasing HDL and lowering LDL and
triglyceride levels in the blood. 51

Vitamin B5 Food Sources

The highest vitamin B5 is found in beef, chicken, organ meats, whole


grains, and vegetables like cabbage, carrots, and tomatoes.

Vitamin B5 Deficiency

Since vitamin B5 is available in various animal and plant-based foods,


a deficiency is rare and limited to severe malnutrition.

Vitamin B6

Vitamin B6 is one of the eight water-soluble vitamins. It is also called


pyridoxine.

73
Functions of Vitamin B6

Vitamin B6 is an essential vitamin used to make antibodies that help


us fight various diseases. 52

It also helps manufacture hemoglobin that carries oxygen in red


blood cells throughout the body.53

Another essential function of vitamin B6 is to break down


proteins. This means the more protein you eat, the more vitamin B6
you need.

It is also required for optimal nerve function, skin and eye health and
helping boost energy levels.54, 55

Vitamin B6 Food Sources

Chickpeas have the highest concentration of this vital vitamin,


followed by beef liver, tuna, salmon, and chicken breasts.

Plant-based sources include potatoes, bananas, nuts, cottage cheese,


etc.

Vitamin B6 Deficiency

Like other water-soluble vitamins, vitamin B6 deficiency is rare as it is


present in various animal and plant-based foods.

74
Let's discuss the remaining water-soluble vitamins in the next
lecture.

75
M3: Micronutrients
L4: Water-Soluble Vitamins: B7, B9, B12 & C

V itamin B7

Vitamin B7, also called biotin, is another B water-soluble vitamin.

Functions of Vitamin B7

By now, you may be clear that all B vitamins play an essential role in
the metabolism of all macronutrients, i.e., carbohydrates, proteins,
and fats.

Furthermore, all eight B vitamins help keep the nervous system in


working order by assisting with neurotransmitters and nerve signals.

Together they protect the brain, improve memory, and help form
defense against cognitive issues and neurodegenerative disorders.

They are needed from our diet daily as the body cannot store them.

Vitamin B7 plays a significant role in keeping the health and strength


of skin, hair, and nail.

A deficiency in vitamin B7 can lead to hair loss and thinning,


including brittle nails and skin problems, but supplementation or

76
taking more than recommended will not promote better hair, nails,
and skin growth.

Biotin or Vitamin B7 plays a significant part in maintaining the health


of our hair, nails, and skin (that's why you find a lot of cosmetics
products like shampoos and skincare products with added biotin in
it).

Another critical function of vitamin B7 is that it helps produce leucine,


an amino acid important for muscle growth.

Vitamin B7 Food Sources

Vitamin B7 is found in various animal and plant-based foods like beef


liver, egg, salmon, pork, seeds, sweet potatoes, legumes, almonds,
spinach, broccoli, and so forth.

Vitamin B7 Deficiency

Biotin deficiency is rare, but when it happens, your skin can become
dry, there can be hair loss, and you may feel a lack of energy. 56

Vitamin B9

Vitamin B9 is one of the water-soluble vitamins. It is also known as


folate.

Vitamin B9 does not participate in energy metabolism. So what


exactly does it do?

77
Let's find out.

Vitamin B9 Functions

Vitamin B9, or folate, helps synthesize DNA and RNA, making it one
of the most important nutrients during pregnancy.

It holds a high significance when it comes to cell division and growth.


This is another reason for it being a vital nutrient during pregnancy,
infancy, childhood, and adolescence.

The human body requires folate to produce healthy red blood cells
and therefore prevent anemia. 57, 58

Vitamin B9 Food Sources

Dark-green leafy vegetables, cowpeas, kidney beans, green peas,


orange, and papaya are high in vitamin B9. It is present in some
animal foods like egg yolk, organ meats, and dairy products.

Vitamin B9 Deficiency

Megaloblastic anemia is the main sign of vitamin B9 deficiency.


Symptoms include headache, shortness of breath, weakness, and
fatigue.

However, vitamin B9 deficiency is rare.

78
Vitamin B12

Vitamin B12 is also another vitamin in the B vitamin family.

It's also called cobalamin. It has various vital functions in our bodies.
Let's discuss the main ones.

Vitamin B12 Functions

Vitamin B12 is responsible for making red blood cells. It is also


involved in DNA formation and regulation.

Vitamin B12 helps prevent megaloblastic anemia, a disorder in which


red blood cells become larger than normal, immature, and few, which
reduces the amount of oxygen carried by the blood to
the tissues. 59

Vitamin B12 is also a crucial nutrient to maintain healthy eyes, brain,


heart, hair, skin, and nails.

Vitamin B12 Food Sources

Vitamin B12 is mainly found in animal foods. The top sources are fish,
meat, eggs, and milk. 60

Nutritional yeast and fortified foods like bread and cereals have this
vitamin.

79
Vitamin B12 Deficiency

An unfortunate fact is that large amounts of folic acid (vitamin B9)


can mask vitamin B12 and result in severe neurological damage
when not treated for a few years.

Additional vitamin B12 deficiency symptoms include poor memory,


dementia, depression, confusion, megaloblastic anemia, weakness,
constipation, and weight loss.

Vegans are at a higher risk of developing vitamin B12 deficiency as


their food sources are mostly limited to animal-based products.

However, nutritional yeast is one such plant-based food that can be


added to a vegan's diet to satisfy their requirement of this critical
vitamin.

Another way to satisfy the vitamin B12 requirement for vegans is to


supplement their diet with vitamin B12.

Vitamin C

Vitamin C is a water-soluble vitamin. It is also called ascorbic acid.

Functions of Vitamin C

Like vitamin E, vitamin C is an important antioxidant and plays a


significant role in scavenging free radicals, protecting us from
cell-damaging. 61

80
Vitamin C helps in collagen synthesis. Collagen is the most common
protein found in the body. It is present in bones, ligaments, tendons,
skin, etc. It can also enhance the absorption of iron. 62

Vitamin C Food Sources

Vitamin C is present in a variety of fruits and vegetables. Red pepper


has the highest content of vitamin C, followed by orange and
grapefruits.

To ensure a high supply of vitamin C daily, it's a good idea to eat at


least five servings of fresh fruits and vegetables.

Vitamin C Deficiency

Scurvy is a disease that may start to manifest if the vitamin C intake


falls below 10mg/day for weeks.

Inflammation in the gums and malaise are the initial symptoms, and if
left untreated, it leads to scurvy. 63

As this disease progresses, joint pain, swollen gums, loosening, or


loss of teeth can happen. If scurvy is left untreated, then it could
prove fatal.

Vitamin C deficiency is rare in the developed world.

In summary, you can see that deficiency of both fat-soluble and


water-soluble vitamins is rare and limited to people who have

81
specific diseases or some disorder, which reduces the body's ability to
absorb these critical vitamins.

Lastly, vitamin deficiency is more in developing nations with


widespread malnutrition.

Let's now discuss minerals starting with the next lecture.

82
M3: Micronutrients
L5: Macro-minerals: Calcium, Phosphorus,
Magnesium

J ust like vitamins, minerals are essential for your body to stay

healthy.

Your body uses minerals for many different jobs, including keeping
your bones, muscles, heart, and brain working properly.

Minerals are also essential for making enzymes and hormones.

The human body needs macro minerals in large quantities, and then
there are micro minerals required by our body in small amounts.

The macrominerals are calcium, phosphorus, magnesium, sulfur,


sodium, chloride, and potassium. The amounts needed are more than
100 milligrams (mg) per day.

Let's discuss all the macro-minerals in some detail.

83
Calcium

Calcium is the most abundant mineral in the body. Calcium is


primarily found in bones, and it constitutes 2% of your total body
weight.

Functions of Calcium

Since most of the calcium is found in our bones, low calcium intake
may result in bone resorption.

It's important to know that our bones are constantly remodeling. In


children and adolescents, bone formation exceeds resorption as the
human body is growing at that time.

However, as we start to age, bone resorption exceeds formation,


which is especially true for postmenopausal women who have to take
extra precautions when it comes to calcium intake to avoid
osteoporosis. ​64

Osteoporosis is a skeletal disorder in which bone mass and bone


strength are affected.

Adequate calcium and vitamin D, along with physical activity, may


reduce the risk of osteoporosis. 65

Calcium is also needed to regulate heart rhythms, aid in muscle


function, and regulate blood pressure and cholesterol levels.

84
Calcium Food Sources

Milk and milk products like yogurt and cheese have the highest
calcium concentrations.

Green leafy vegetables like spinach, kale, and broccoli have some
calcium, but the bioavailability decreases because of anti-nutrients
like oxalic acid.

Calcium Deficiency

There is no calcium deficiency in the short term, as blood calcium


levels are tightly regulated.

But in the long run, calcium deficiency may result in bone loss,
especially in children and postmenopausal women.

Vegans or people with lactose intolerance are also at risk of calcium


deficiency.

Calcium deficiency eventually can lead to bone fractures and


osteoporosis.

Phosphorus

Phosphorus is a mineral that makes up 1% of a person's total body


weight. It is the second most available mineral in the body after
calcium.

Most of the body's phosphorus is in the bones, teeth, DNA, and RNA.

85
Functions of Phosphorus

Phosphorus and calcium play a significant role in creating bones and


teeth. ​66

Phosphorus exists in every human body cell and contributes to RNA


and DNA formation, responsible for the storage and
transmission of genetic information. ​67

Adequate phosphorus is essential for maintaining essential cellular


functions, nerve conduction, and energy production.

Food Sources of phosphorus

Like calcium, dairy products like milk, yogurt, and cheese are high in
phosphorus. Other animal-based foods like salmon, chicken, and beef
are high in phosphorus.

Plant-based foods that contain phosphorus are lentils, kidney beans,


rice, cashew, potatoes, etc.

Phosphorus Deficiency

It's rare to run low on phosphorus as it is readily available in many


foods.

A shortage can sometimes happen, especially in individuals suffering


from alcohol abuse, eating disorders, anorexia, and certain inherited
disorders.

86
Symptoms of deficiency include anemia, muscle weakness, bone pain,
and numbness in the arms and legs.

Magnesium

Magnesium is an essential mineral and necessitates 300 biochemical


reactions in our body.

Magnesium helps maintain healthy nerve and muscle function, strong


bones and regulates blood glucose and blood pressure.

An adult body contains about 25g of magnesium, of which 50-60


percent is in bones and the remaining in soft tissues.

Functions of Magnesium

Magnesium may improve bone health both directly and indirectly, as


it helps regulate calcium and vitamin D levels, two other nutrients
vital for bone health.

Magnesium is a cofactor of various carbohydrate oxidation enzymes


and plays an essential role in the cell membrane's
glucose transporting mechanism.

It is vital for biochemical processes involving the formation and


utilization of ATP in the cell. 68

Magnesium is required for DNA replication, transcription into RNA,


and translation into protein.​69

87
Magnesium Food Sources

Foods high in magnesium are nuts, seeds, legumes, spinach, and


whole grains. It is present in very low amounts in salmon and milk.

Magnesium Deficiency

Overall, magnesium deficiency in healthy people is rare, as the


kidneys strictly regulate magnesium content by limiting the urinary
excretion of this mineral if the dietary consumption is low.

It can result in loss of appetite, nausea, vomiting, fatigue, and muscle


weakness.

Let's continue our discussion of macro-minerals in the next lecture.

88
M3: Micronutrients
L6: Macro-minerals: Sodium, Chloride, Potassium,
Sulfur

S odium

Sodium is a mineral and one of the chemical elements found


in salt. It is found mainly in blood plasma and extracellular fluid.

The body obtains sodium through food and drink and loses it
primarily in sweat and urine.

Most of the sodium we consume is salt, sodium chloride-40%


sodium, and 60% chloride.

Functions of Sodium

Sodium is an electrolyte in the body fluids like the blood that carry an
electric charge. Sodium and other minerals like potassium help the
body keep fluids in a healthy balance.

The heart, muscle, and nerve cells use electrolytes like sodium to
carry electrical impulses to other cells. 70

89
The Daily Value (DV) for sodium is less than 2,300 milligrams (mg)
per day.

But due to a significant portion of calories coming from processed


foods (high in sodium), the average American consumes around
3,400mg of sodium per day.

Sodium​Food Sources

You don't have to worry about getting enough sodium in your diet.

If most of your calories come from processed foods, you should be


more worried about how you can lower your sodium intake!

Monosodium glutamate(MSG), baking soda, sodium nitrite, sodium


saccharin, and sodium benzoate are different sodium forms added to
many food products. These increase the flavor, texture, appearance,
and shelf life of the foods.

It is good to eat most of your calories from homemade foods


prepared from fresh, local, and seasonal ingredients for healthy
sodium intake.

Sodium ​Deficiency

It's extremely rare to run low on sodium as most people eat


significant calories from processed foods!

If a deficiency occurs (hyponatremia), it can result in headaches, loss


of appetite, vomiting, muscle cramps, fatigue, and convulsions.

90
Chloride

Chlorides are present in nature, including mineral sediments, natural


water, human and animal excretions, wastewater, and food.

Most of the chloride is consumed in the form of salt (sodium chloride).

Chloride helps balance the amount of fluid inside and outside of your
cells. Approximately 10% is found in our cells, whereas the remaining
is present in the extracurricular fluid.

Sodium and chloride are found outside the cell in the extracellular
fluids, and potassium, magnesium, and phosphorus within the cells.

Functions of Chloride

Chloride, after sodium, plays a vital role as an electrolyte in our body.


It regulates body fluids, electrolyte balance, nerve, and muscle
function. 71

It balances the blood pH and is an essential component for assessing


many pathological conditions.

Chloride is secreted as hydrochloric acid (gastric juice) in the stomach


for protein digestion absorption of nutrients like
vitamins, calcium, zinc, and folic acid. 72

91
Chloride Food Sources

Dietary chloride comes almost entirely from sodium chloride or table


salt.

Vegetables such as seaweed, rye, tomatoes, lettuce, celery, and


olives contain chloride.

Chloride is naturally there in almost all water forms.

Chloride​​Deficiency

Chloride deficiency is very rare, as most foods containing sodium


also provide chloride. Hypochloremia is a condition when the volume
of chloride ions is low in the body. 73

It can happen due to low salt intake (vomiting, sweating), with certain
medications such as laxatives, diuretics, and other health conditions.

Symptoms can be dehydration, vomiting, diarrhea, and


breathlessness.

Hypochloremia can also occur with hyponatremia (low sodium


levels). Chloride losses can be substantial in infants from diarrhea or
vomiting due to infection. 74

92
Potassium

Potassium is one of the seven essential macrominerals and


electrolytes needed to maintain our body.

It is present both inside and outside the cells. However, potassium


concentration is ~30 times higher inside the cell than outside!

Functions of Potassium

Together with sodium, it regulates the blood plasma and


extracellular fluid volume.

Potassium also helps by regulating the heartbeat, assists in the


functioning of nerves and muscles. It also helps maintain the proper
fluid balance.

Potassium is vital for synthesizing protein and metabolizing


carbohydrates.

Potassium is excreted mainly in the urine, some in the stool, and a


minimal amount as sweat.

Our body absorbs 85-90% of the dietary potassium from the foods
we eat.

93
Potassium Food Sources

Potassium is available from a variety of vegetables, fruits, dairy, nuts,


and unrefined foods.

Lentils and beans are also high in this essential mineral.

Potassium Deficiency

Hypokalemia​(​low potassium level) occurs in the body due to


excessive urination because of prescription medications, severe
sweating, vomiting, overuse of laxatives, kidney disease, and
genetic disorders.

Mild hypokalemia symptoms are constipation, fatigue, and muscle


weakness. 75, 76

However, potassium deficiency is rare, especially in people with


healthy kidney function.

Sulfur

Sulfur is an element that exists in nature and is freely available in


soil, plants, foods, and water.

Sulfur is supplied mainly by the intake of two amino acids,


methionine, and cysteine, found in plant and animal proteins.

Sulfur becomes an essential constituent of amino acids, proteins,


enzymes, vitamins, and other biomolecules.

94
Function of Sulfur

Cysteine and methionine(sulfur-containing amino acids)are necessary


to make and maintain glutathione, the master antioxidant.

It neutralizes free radicals and reactive oxygen compounds, regulates


the nitric oxide cycle (crucial for inflammation), helps the liver process
toxins, and plays a role in DNA synthesis.

Sulfur-containing compounds possess a range of biological activities,


including antiviral, antibacterial, antiallergic, and
antimalarial. 77

Sulfur Food Sources

Food sources of sulfur-containing amino acids(SAA) are allium


vegetables like onion, leek, garlic, and cruciferous vegetables like
cabbage, kales, and broccoli.

Egg whites, chicken, fish, beef, and dairy products are good sources
of sulfur.

Legumes, nuts, seeds, whole grains, and certain condiments also are
rich in sulfur.

Drinking water also contains sulfur, depending on the source.

95
Sulfur Deficiency

Sulfur deficiency is not common, but if manifested, it may result in


acne, brittle nails, thinning of hair, depression, memory loss, and
gastrointestinal issues.

96
M3: Micronutrients
L7: Micro-minerals: Iron, Zinc, Copper, Manganese

E ven though our bodies need microminerals in minimal

quantities (0.2 to 15mg/day), they are still essential to our diet daily.

There are nine microminerals: Iron, Zinc, Copper, Manganese,


Selenium, Chromium, Iodine, Molybdenum, and Cobalt.

Let's start with iron.

Iron

Iron is a micromineral essential for all living organisms and is found in


every body cell.

Functions of Iron

Roughly 70% of the body's iron is utilized to make hemoglobin.


Haemoglobin's primary role is to transport oxygen from the lungs to
body tissues to maintain essential life functions. 78

Human body cells require iron to convert energy from food into ATP,
a primary energy source of the body.

97
Iron is vital for synthesizing cofactors necessary to the enzymes
involved in DNA synthesis and cellular creation and growth.

Iron Food Sources

There are two kinds of dietary iron, known as Heme and Non-Heme.

The body quickly absorbs heme iron. We get heme iron from animal
sources like organ meat, seafood, and poultry.

Non-heme iron is from plant-based sources like beans, spinach, nuts,


soy, and dry fruits.

Consuming vitamin-C-rich foods alongside non-heme sources of iron


can increase iron absorption.

The daily iron requirement for vegetarians is 1.8 times higher than for
non-vegetarians.

Iron Deficiency

Blood loss is the most common cause of iron deficiency. ​

Menstruation, poor diet, and malabsorptive disorders can also


cause iron depletion. 79, 80

A deficiency of iron in the blood is called Iron deficient Anemia.

98
Mild or moderate iron deficiency anemia may not have any signs or
symptoms. The symptoms of anemia can be fatigue, shortness of
breath, or chest pain.

​Zinc

Zinc is an essential trace mineral and is responsible for physiological


processes.

Zinc is not stored in the body and must be consumed daily to


guarantee sufficient supply.

Functions of Zinc

Zinc is found in most of the cells throughout the body.

It is one of the crucial regulators of cellular function and the body's


immune system. 81

Zinc is responsible for the catalytic activity of more than 100 different
enzymes.

Zinc in proteins is essential for maintaining protein structure, stability,


and regulating gene expression.

Zinc and antioxidants delay the progression of age-related macular


degeneration (AMD) and vision loss by preventing cellular damage in
the retina. 82

99
Zinc Food sources

Animal proteins are good sources of dietary zinc- seafood, red meat,
lamb, and chicken's dark meat.

Vegetarian sources are nuts, beans, whole grains, and dairy products.

Vegetarians may need more zinc than recommended due to the low
bioavailability of zinc from plant-based foods.

Zinc​​Deficiency

Low dietary intake, malabsorption, chronic illnesses like diabetes,


cancer, and liver diseases can create zinc deficiency.

Symptoms are loss of appetite, frequent infections, retarded growth,


and anemia. It can result in hair loss, loss of sense of taste, and smell
in severe cases. 83

Low zinc levels are evident in vegetarians, pregnant and lactating


women, and anyone suffering from gastrointestinal diseases.

100
Copper

Copper is an essential trace mineral vital to the body's health from


fetal development to old age.

Copper in the body is located in the liver, bones, and muscle, but
copper traces occur in all body tissues.

Most copper is excreted in bile and a small amount in urine.

Functions of Copper

Copper plays a vital role in our metabolism, primarily because it


allows many critical enzymes to function correctly.

Copper enzymes are known as cuproenzymes, regulate energy


production, red blood cells, connective tissue synthesis,
neurotransmitter synthesis, and antioxidant action. 84

Copper is necessary for the maintenance of a healthy white blood cell


count. Your body also needs copper for brain development and iron
absorption.

Copper Food Sources

Animal sources of copper are shellfish, oysters, crab, and organ meat.

Plant sources rich in copper are whole grains, beans, dark leafy
greens, potatoes, and chocolate.

101
Seeds and nuts rich in copper are cashews, hazelnuts, sunflower
seeds.

Copper​Deficiency

Copper deficiency can result from malnutrition, malabsorption, or


excessive zinc intake and can be acquired or inherited.

The symptoms are low white blood cells with an increased risk of
infection, fatigue, anemia, osteoporosis, hypopigmentation,
connective tissue disorder, nerve damage, and muscle weakness. 85

Manganese

Manganese is a trace mineral, vital but required in a small quantity.

Manganese is ingested through the gastrointestinal tract and stored


in the liver, pancreas, bones, kidneys, and brain.

Functions of Manganese

Manganese is essential for forming healthy cartilage and bone for


blood clotting and helps in wound healing.

It plays a role in numerous chemical processes, including synthesizing


nutrients like cholesterol, carbohydrates, and proteins.​86

102
Manganese Food Sources

Plant-based foods rich in manganese are sprouted grains, legumes,


beans, nuts, and seeds.

Animal sources are clams, oysters, and mussels.

Manganese Deficiency

Manganese deficiency is rare and usually limited to people suffering


from medical issues like diabetes, osteoporosis, epilepsy.

Signs of a potential manganese deficiency may include impaired


growth, impaired reproductive system, and skeletal system
abnormalities. 87

Manganese deficiency might also affect and change lipid and


carbohydrate metabolism and cause abnormal glucose tolerance.

In the final lecture on micronutrients, let's discuss the remaining


micro-minerals.

103
M3: Micronutrients
L8: Macro-minerals: Selenium, Chromium, Iodine,
Molybdenum, Cobalt

S elenium

Selenium is a trace mineral and is available naturally in foods.

Most selenium is stored in muscle tissue, although the thyroid gland


holds the highest selenium concentration due to various
selenoproteins that assist with thyroid function.

Functions of Selenium

Maintaining a physiological concentration of selenium is a


prerequisite to preventing thyroid disease and preserving overall
health. 88

Selenium is a vital component of various enzymes and proteins called


selenoproteins. These have antioxidant properties that help break
down peroxides, damaging tissues and DNA, leading to inflammation
and other health problems. 89

104
Selenium Food Sources

Animal sources of selenium are chicken, turkey, beef, seafood, and


eggs.

Plant sources are brazil nuts, beans, lentils, grains, green vegetables,
bread, and dairy.

Selenium Deficiency

Selenium deficiency is rare; however, if manifested may cause poor


immune function and cognitive decline. ​90

Chromium

Chromium is a naturally occurring element found in rocks, animals,


plants, soil, and volcanic dust and gases.

Dietary chromium is poorly absorbed, and levels of absorption


decrease with age.

Only a tiny amount of the chromium from food is absorbed, and the
absorption is better if eaten with foods containing vitamin C and
niacin.

Functions of Chromium

Chromium is an essential mineral that has a beneficial role in


regulating insulin action and its effects on carbohydrate, protein,
and lipid metabolism. 91,
​ 92

105
It stimulates fatty acid and cholesterol synthesis, which is vital for
brain function.

Chromium Food Sources

Chromium is widely available in the food supply, but most foods


provide only tiny amounts.

The best chromium sources are broccoli, liver, brewer's yeast,


potatoes, whole grains, seafood, nuts, egg yolk.

Grape juice and red wine are good sources of chromium.

Foods high in simple sugars and dairy products are usually low in
chromium.

Chromium Deficiency

Dietary chromium is poorly absorbed, and levels of absorption


decrease with age.

Low chromium levels will lead to impaired glucose tolerance,


resulting in reduced blood sugar control in people with type-2
diabetes. 93

Symptoms of chromium deficiency can include weight loss, confusion,


and impaired coordination.

106
Iodine

Iodine is one of the essential elements required for healthy human


growth and development.

Iodine does not occur naturally in specific foods and is present in the
soil and absorbed through foods grown on that soil.

About 70-80% of iodine is in the thyroid gland in the neck; the rest is
in the blood, muscles, ovaries, and other body parts.

Functions of Iodine

Iodine's principal physiological role in the human body is to produce


the thyroid-stimulating hormone (THS) known as thyrotropin.

Thyroid hormones regulate crucial biochemical reactions, including


protein synthesis and enzymatic activity, and are critical determinants
of metabolic activity.

Iodine is an essential component of the thyroid hormones


triiodothyronine (T3) and thyroxine (T4) and is vital for healthy
thyroid function.

All cells in our body depend on T3 and T4 to regulate their


metabolism.

107
Iodine Food Sources

Seafood is abundant in iodine because marine animals absorb some


of the iodine naturally present in seawater.

Certain types of edible seaweed such as wakame, nori, and kombu


are also rich in iodine.

Eggs, fruit, vegetables, grain products, dairy, and poultry are good
sources of iodine, but the amount varies on the soil and fertilizer's
iodine content.

Iodized salt is also one of the most common food products through
which we get iodine.

​Iodine Deficiency

Iodine deficiency results mainly from geological rather than social


and economic conditions.

In areas where the soil is iodine deficient, those who do not use
iodized salt and pregnant women are more prone to be iodine
deficient.

Inadequate iodine intake leads to insufficient production of thyroid


hormones, which adversely affect the muscle, heart, liver, kidney, and
the developing brain.

108
Iodine deficiency disorders (IDD) include hypothyroidism, mental
retardation, goiter, and varying degrees of other growth and
developmental abnormalities. 94

Molybdenum

Molybdenum is an essential trace element for virtually all life forms.

The body uses molybdenum to process proteins and genetic material


like DNA and RNA.

Functions of Molybdenum

Molybdenum is a structural constituent of molybdopterin, a cofactor


synthesized by the body and required for the function of four
enzymes:

Sulfite oxidase
Xanthine oxidase
Aldehyde oxidase
Mitochondrial amidoxime reducing component (mARC)

These enzymes metabolize sulfur-containing amino acids and


heterocyclic compounds, including purines and pyrimidines. 95

Xanthine oxidase, aldehyde oxidase, and mARC also metabolize


drugs and toxins. 96

109
Molybdenum Food sources

The molybdenum content of foods depends on the soils and water


used in irrigation.

Plant sources of molybdenum are whole grains, rice, banana, green


leafy vegetables, nuts, and all kinds of beans.

Animal sources are beef, chicken, eggs, and dairy products.

Molybdenum Deficiency

Molybdenum deficiency is rare but can occur in people with a genetic


mutation that prevents molybdopterin synthesis.

Symptoms can be headaches, vomiting, night blindness, rapid heart


and respiratory rates, and coma. 97

Cobalt

Cobalt is a trace element essential for the human body and can occur
in organic and inorganic forms.

The organic form is a necessary component of vitamin B12 and is


essential for making red blood cells (RBC). 98

110
Functions of Cobalt

Cobalt plays a significant role in forming amino acids and some


proteins in nerve cells and creating neurotransmitters indispensable
for the organism's correct functioning.

Cobalt is also part of the biotin-dependent Krebs cycle, in which the


body breaks down sugars into energy. 99

Cobalt Food sources

Animal sources rich in cobalt are fish, eggs, organ meat, muscle meat,
poultry, and milk.

Plant sources are Nuts, seeds, green leafy vegetables, broccoli, peas,
beans, and root vegetables.

Cobalt Deficiency

Cobalt deficiency is strongly related to disturbances in vitamin B12


synthesis.100

Cobalt deficiency can cause pernicious anemia. The symptoms can


include numbness, fatigue, tingling in your hand and feet, nausea,
appetite loss, difficulty maintaining balance, weight loss, and
headache.

111
M4: Special Compounds
L1: Fiber : Definition, Types & Health Benefits

H i students. Welcome to the module on Special compounds.

In this module, we'll discuss the following:

Fiber

Probiotics

Water

Let's get started with fiber.

Fiber

Fiber is a type of carbohydrate that our body cannot digest or

absorb. It is referred to as ​bulk​or ​roughage.​

Because our bodies cannot digest fiber, it passes through our


stomach, small intestines, colon, and out of our bodies relatively
intact.

112
Types of Fiber

Soluble Fiber

Soluble fiber can dissolve in water and form a gel-like substance.


Some examples of soluble fiber are gum, pectin, and mucilage.

Food sources rich in soluble fiber are peas, oats, apples, beans,
carrots, and barley.

The main benefits of soluble fiber are that it helps to reduce blood
glucose levels and blood cholesterol levels.

Insoluble Fiber

Insoluble​fiber, as the name suggests, cannot dissolve in water.


Examples include cellulose, lignin, hemicellulose.

Food sources rich in insoluble fiber are whole bran, whole-wheat like
roti, potatoes, and beans.

The main benefit of insoluble fiber is that it helps you keep regular by
speeding up the passage of foods from the intestines. 101

Health Benefits of Including Fiber in your Diet

As dis​cusse​d, insoluble fiber helps add bulk to the stool, making it


easier to pass, thus decreasing the chance of constipation.

113
Constipation is one of the most common gastrointestinal issues that
people experience worldwide!

The most important thing when it comes to weight loss is to deal


with hunger and cravings. This is because to lose weight; it's
essential to follow a calorie deficit diet.

When on a caloric deficit diet, almost everyone has to deal with


cravings and hunger.

A high fiber diet is more filling as it helps stabilize your blood sugar
levels, significantly reducing your cravings and hunger. 102

Another important aspect of a high fiber diet is that almost every


high fiber foods are ​nutrient-dense, meaning they are high in vitamin
minerals which further helps reduce cravings. 103

This is because cravings are simply a cry from your body to ingest
more micronutrients that it needs to deal with billions of chemical
reactions happening in your body at any given point in time.

High fiber intake is strongly linked to a reduction in heart disease.


An umbrella review was conducted by Marc P. McRae, published in
2017.​104

This umbrella review included all meta-analyses or systematic


reviews.

A total of 31 meta-analyses were included in this umbrella review.

114
All of these high-quality studies reported that eating a high fiber diet
significantly reduces the relative risk of cardiovascular disease, stroke,
and coronary heart disease.

The apparent reason was that fiber acts on low-density lipoprotein


(bad cholesterol) and reduces it, thus lowering the risk of heart
disease and other cardiovascular diseases.

115
M4: Special Compounds
L2: Fiber : Optimal Fiber Intake, Foods High in Fiber

H ow Much Fiber Do You Really Need Everyday?

Opti​m​al Fiber intake is dependent on one's age and gender.

Men need 38g+ fiber daily. Women need 25g+ fiber daily.

Find all tables and images in the Resource manual. I hope you have
already downloaded it. :)

Foods High in Fiber

It's important to eat a variety of high fiber foods to ensure that you
get both types of fiber, i.e., soluble and insoluble.

You don't need to be particular about getting a fixed amount of a


specific type of fiber, as almost all fiber foods contain varying
amounts of fiber types in them.

Just focus on including the following foods almost on a daily basis.


This will ensure that you reach the optimal fiber intake according to
your age and gender.

116
Fiber in Legumes

Foods that contain the highest concentration of fiber are legumes.


As we learned in the carbohydrate module, legumes are further
subdivided into lentils (dal) and beans (kidney beans, chickpeas, etc.)

Dal's and beans are ~25% fiber by weight. This means that 100g of
raw quantity provides 25g of fiber.

I eat 350g of dal or beans daily, which provides me with 25g of fiber.

Therefore, 100g of cooked dal/beans with a medium consistency will


provide 7g of fiber which is very high.

Fiber in Fruits

Fiber intake in most fruits is 2-3g for every 100 grams.

Avocado is one fruit that is super high in fiber, providing 7g of fiber


per 100g.

Berries like blackberries and raspberries contain between 5-7g per


100g.

Pomegranate has 4g/100g.

117
Fiber in Vegetables

The fiber in most vegetables is also between 2-3g/100g. Your regular


veggies like broccoli, spinach, carrots, brussels sprouts, okra (bhindi),
sweet potatoes, etc., contain between 2-3g/100g.

However, lima beans, peas, squash, and artichoke are loaded with
fiber at 6g/100g!

Fiber in Whole Grains

Oats, barley, ragi, brown rice, roti are all high fiber foods.

Just make sure that you source the ingredients from a health store, as
most commercially available grains and oats are highly processed,
leaving very little fiber in them!

Next lecture, we'll discuss probiotics.

118
M4: Special Compounds

L3: Probiotics : Definition, Health Benefits & Top Foods

S cientists have started to call our gut 'The Second Brain.' 105

According to Michael Gershon, our gut has about 100 million


neurons, more than the spinal cord or the peripheral nervous system,
author of the book 'The Second Brain.'

Your brain and gut are connected by a visceral nerve called the vagus
nerve. It is an information highway where the information flows from
your gut to the brain and vice-versa. 106

Roughly 70% of our immune system is located within the gut in the
form of gut-associated lymphoid tissue. 107

Literally, there are more immune cells in your gut than anywhere in
your body.

Another amazing fact is that more than 90% of the 'feel-good


hormone serotonin is produced in your gut.

119
This hormone affects your mood and well-being, and the right
balance is vital to regulate mood, appetite, and overall well-being. 108

A collection of bacteria, fungi, and viruses are housed in your gut.


Out of these microbes, bacteria are the most studied, and they
outnumber other microbes by two to three times.

Now, whenever the word bacteria comes to our mind, we think of


germs and disease, right?

Not really!

That's just part of the story.

Quite simply, bacteria in your gut are divided into good and bad
bacteria, just like good cholesterol and bad cholesterol.

Bad bacteria is bad.

They multiply, and they mean harm. Some examples are e-Coli and
salmonella.

Whereas good bacteria are famously known as "probiotics," which


exist to protect their host body, that is us!

They play various important roles in our bodies.

Let's define probiotics and analyze some evidence on how probiotics


may affect our health.

120
What are Probiotics?

Probiotics are simply the good bacteria in your gut. However, some
yeast can also act as probiotics.

There are different types and strains of probiotics offering unique


health benefits.

The most common variety of bacteria in our gut is:


Lactobacillus and bifidobacterium.

Health Benefits of Probiotics

1) Helps us digest and absorb our food

Most good bacteria are found in your large intestine (with varying
levels in other parts and organs of your body), but they are primarily
found in your large intestine.

So whatever food particles that your stomach and small intestine


cannot digest, these good bacteria help.

They also help in the synthesis of Vitamin K2, folate, short-chain fatty
acids like butyrate (SCFA), and some B vitamins 109, 110, 111, 112

121
2) Stimulates the Immune System

About 70 percent of the immune system is located in our gut.

This makes a lot of sense since the food that we eat and drink is
loaded with pathogens, viruses, and bacteria, and the ideal location
of our immune system is the gut because it can fight off these
unwanted invaders more effectively.

3) Modulates the neurotransmitters responsible for one's appetite


and mood

There is also enough evidence that the gut microbiota modulates


neurotransmitters like serotonin, GABA, and even dopamine. 113, 114

The gut is the largest site for serotonin as it is produced by the gut
microbes and the gut cells. 115

Literally, 90% of the serotonin in the body is produced in the gut.

4) Lowers the oxidative stress and inflammation

Further, our gut microbiome plays a crucial role in controlling


oxidative stress and inflammatory responses and improving
metabolism and energy expenditure during intense exercise. 116

122
5) Fend off bad bacteria

Probiotics help to fend off bad bacteria that try to harm you.

Just like the ideal ratio between Omega 3 and Omega 6 should be
1:2, the same way, the ideal ratio between good and bad bacteria
should be 85:15.

If this ratio is disrupted due to changes in one diet and lifestyle like
less sleep, more stress, high intake of alcohol, smoking, antibiotic use,
consumption of fast and junk food, consumption of conventional
dairy, etc., then certain symptoms like headaches, mood swings,
weight gain, acne, gas, bloating, pain in stomach start to crop up.

Over time these symptoms [which are a sign by your body that there
is something wrong] may potentially manifest into full-bore diseases
like IBS, Crohn's disease, autism, cancer, and so forth. 117

6) Weight Loss and your Gut

A gut dysbiosis can occur when bad bacteria in your gut vastly
outnumber good bacteria.

This condition can disrupt normal metabolic functioning and can


cause insulin resistance.

All this can ultimately result in unwanted weight gain. And so, the
opposite can happen if you optimize your gut bacteria. 118

Remember the ratio between good vs. bad bacteria? Yes, 85:15.

123
Buttermilk, yogurt, sauerkraut, kimchi, miso, tempeh, kanji, natto are
some of the foods rich in probiotics.

I strongly recommend that you start to include a few of these foods in


your diet daily.

124
M4: Special Compounds

L4: Water: Health Benefits & Optimal Water Intake

W ater is essential for life. Approximately 65% of the adult

body is water. This percentage is more in infants and less in the


elderly.

Water is indeed an essential nutrient, and every organ and system in


the human body counts on the water to function optimally.

Why Water is Important for Health

Water's importance is established because most of us can survive


without food for several weeks, but when it comes to water, the time
is limited to only a few days!

It is a vital nutrient required in optimal quantity daily.

Before I discuss how much water one should consume daily, let's
understand the critical role in the human body.

125
Water and Brain

According to BrainMD.Com:

"Your brain is 80% water, your muscles (including your heart) are
75% water, your blood is 83% water, your lungs are 90% water, your
skin is 64% water, and even your bones are 30% water."

Optimal water intake helps with maintaining memory function,


improving concentration and cognition.

Mild dehydration, which is 1-3% bodyweight loss of water, can alter


brain function.

Cognitive functions such as concentration, alertness, and short-term


memory are affected negatively during mild dehydration. 119

Water and Weight Loss

Whenever I put my clients on a calorie deficit diet, they complain of


increased hunger.

I tell them it is not hunger. It's just cravings.

To curb their cravings, I suggest that they include water as the first
thing they should reach for.

Other zero-calorie beverages include black coffee, apple cider


vinegar, lemon juice, and green tea.

126
It's important to note that these beverages are 99% water and
effectively curb cravings and act as appetite suppressants.

A long-term randomized controlled trial done on premenopausal


overweight women concluded that increased water intake resulted
insignificant loss of body weight and fat over 12 months.120

A study in the Journal of Clinical Endocrinol Metabolism concluded


that drinking 500ml of water increased metabolic rate by 30%. The
increase occurred within 10 minutes and reached a maximum
after 30-40 min.​121

Various other studies support the same results that water intake
increases metabolic rate.​122, 123

Water and Skin Health

We have learned that skin is 64% water, and increasing your water
intake will positively affect your skin health.

Optimal water intake helps get rid of skin toxins resulting in radiant
skin.

Enough water intake also reduces water retention. Water retention


occurs due to less water intake as the body retains more water to
prevent dehydration.

However, there is no reason for the body to retain water when you
drink enough water! This reduces the 'puffy' look and makes you look
toned.

127
Optimal Intake of Water Per Day

Now that we have learned the best ways to drink high-quality


energized water for good health, let's understand how much water
you should drink every day for optimal cognitive, mental, and overall
health.

Just like one's protein intake is intrinsically linked with their activity
levels, the same way your water intake will vary based on where you
live and how active you are.

If you live in a country where it's hot and humid most of the time, your
water intake will be higher because you will lose more water in
sweat.

Similarly, if you indulge in moderate-to-high intensity workouts, your


water intake will be more than people who lead a sedentary lifestyle.

In 1945, the National Academy of Sciences advised 1 milliliter of


water for every calorie you eat.

For example, if you eat a 2,000 calorie diet, you should drink 2 liters
of water per day.

When you average the intake touted by most health authorities, it


comes to roughly ~2 liters per day.

This is roughly eight glasses (8 ounces) of water.

128
8×8 is a famous water unofficial recommendation that most people
abide by and has been quite popular in the press for decades.​124, 125

However, this recommendation does not consider one's gender, age,


activity levels, the kind of climate they live in, and, most importantly,
how much water they are ingesting through foods and beverages.

The reality is that most people consume approximately 20% of their


water via food.

Most fruits and vegetables are 75-99% water. Meats and poultry are
50-65% water.

Many low-calorie beverages like black coffee, tea, green tea, coconut
water, lemon juice, vegetable juices are all 99% water and add
significantly to your water intake.

The Bottomline on Optimal Water Intake

There is no official figure from any health authority on the optimal


water intake. However, they recommend that the water intake varies
for each individual and can vary depending on their lifestyle and
where they live.

The best way to ensure optimal water intake is to let your body be
your guide.

For starters, ensure that your urine color is always light yellow in
color or colorless.

129
A dark yellow or orange color indicates dehydration.

Also, please note that the moment you start to feel thirsty, you are
already dehydrated. So it's a good idea to drink water throughout the
day.

To ensure this, it's essential to keep a ~1-liter bottle of water on your


work desk or in your office where it is clearly visible.

This lecture marks the end of this module.

This fundamental course is not over yet. The next module will be
interesting as I will bust the top nutrition myths that are still
prevalent today.

Let's continue in the next lecture.

130
M5: Nutrition Myths & Facts

L1: Myth #1: A Diet High in Fats is Bad for Your


Health

T ogether with carbohydrates, fats are a primary source of

energy. Fat is a dense source, providing nine calories per gram


consumed.

Besides being a primary energy source, dietary fats perform a host of


essential functions in our body.

Each cell's membranes are composed of protein and lipids, including


phospholipids, cholesterol, and triglycerides.

The cell membrane acts as a barrier between the inside and outside,
controlling the movement of substances in and out of the cell.

Our brain is ~60% lipids, with DHA (a type of omega-3 fatty acid)
being the most prominent. 126

The retina of the eyes also contains DHA. 127

131
Without enough fat in the diet, the body cannot absorb fat-soluble
vitamins A, D, E, & K.

Fat cells stored in adipose tissue insulate our body and protect it from
extreme cold and heat.

The extra padding of fat on our hands, legs, and buttocks helps in
physical activities like swimming, running, and other sports. It also
protects us from physical trauma.

However, this does not mean we should be overweight. Excess body


fat can cause a lot of medical problems. 128

Akash's recommendation regarding daily dietary fat intake

Fats can be your best friend or your worst enemy.

It is easy to get confused about fats because some are good and
some are bad.

I recommend eating at least 20% (can easily go up to 80% in a


Standard Ketogenic Diet) of calories from good fat sources such as
omega-3s, monounsaturated fats, and saturated fats.

And limit the consumption of polyunsaturated fats, especially from


vegetable oils.

A 2018 year-long randomized control trial of 609 participants


conducted by Dr. Christopher D Gardner John F Trepanowski et al.
concluded that there was no significant difference in weight loss

132
between a group who ate a healthy low-carb diet and another group
that ate a healthy high-fat diet. 129

The next two myths will make the following two questions clear:

1) Is Saturated Fat Healthy?

2) Are Vegetable Oils good for health?

Let’s continue in the next lecture.

133
M5: Nutrition Myths & Facts

L2: Myth #2: Saturated Fats Are Bad For Your Health

“W hen saturated fat got mixed up with the high sugar

added to processed food in the second half of the 20th century, it got
a bad name."

-Robert Lustig UC San Francisco Pediatric Endocrinologist

Why was saturated fat demonized in the first place?


It all started with Ancel Keys and the Seven Countries Study.1

Keys launched the Seven Countries Study in 1958 to research the


relationship between dietary patterns and the prevalence of coronary
heart disease.

He uncovered a direct link between heart disease from high total


serum cholesterol and saturated fat intake.

However, the study was seriously flawed; Keys started with data
from 22 countries and omitted the data from the countries that didn't
fit his hypothesis! 130

134
For the last four decades, because of him and his deceptive study, we
have been eating cereals with skimmed milk instead of whole egg
omelets made in butter.

The American Heart Association 2 recommends aiming for dietary


patterns that derive 5 to 6 percent of its calories from saturated fat.

For a 2000-calorie-a-day diet, this equates to around 13 grams of fat


(120 calories).

They state that saturated fats raise the level of cholesterol in your
blood but fail to delineate which type of cholesterol they are referring
to!

They suggest replacing foods high in saturated fats with foods high
in monounsaturated and or polyunsaturated fats by eating foods with
liquid oils.

On the contrary, saturated fats are protective and found in real food,
not junk.

Unfortunately, after four decades of embracing the idea that


saturated fat is bad for your heart, it will require no less than a
revolution to break free of this massive misinformation, but times
have started to change.

Fats and oils are made of collections of molecules called triglycerides.

135
Saturated fats are triglycerides that contain only single covalent
bonds between fatty acid carbon atoms.

Because they lack double bonds, each carbon atom is saturated with
hydrogen atoms.

A few examples of foods high in saturated fats are ghee, coconut oil,
lard, tallow, and red meat.

Is Saturated Fat Good for Health?

In 2010, a meta-analysis involving more than 300,000 individuals


found no significant evidence that dietary saturated fat is associated
with an increased risk of coronary heart disease or cardiovascular
disease. 131

A recent British Medical Journal article by British cardiologist Aseem


Malhotra, an interventional cardiology specialist registrar at Croydon
University Hospital in London, states:

"The mantra that saturated fat must be removed to reduce the risk of
cardiovascular disease has dominated dietary advice and guidelines
for almost four decades. Yet scientific evidence shows that this advice
has, paradoxically, increased our cardiovascular risks.

The aspect of dietary saturated fat that is believed to have the


greatest influence on cardiovascular risk is elevated concentrations of
low-density lipoprotein (LDL) cholesterol.

136
Yet the reduction in LDL cholesterol from reducing saturated fat
intake seems to be specific to large, buoyant (type A) LDL particles,
when in fact, it is the small, dense (type B) particles (responsive to
carbohydrate intake) that are implicated in cardiovascular disease.

Indeed, recent prospective cohort studies have not supported any


significant association between saturated fat intake and
cardiovascular risk. Instead, saturated fat has been found to be
protective.” 132

A meta-analysis of observational studies and 27 randomized,


controlled trials published in the Annals of Internal Medicine also
conclude that current evidence does not clearly support
cardiovascular guidelines that encourage high consumption of
polyunsaturated fatty acids and low consumption of total saturated
fats.

This particular analysis included data from more than 600,000


people in 18 countries. 133

Nature cannot be wrong.

Did you know that mother's milk has more than 50 percent of calories
from saturated fat and a higher proportion of cholesterol ?

This is because cholesterol and saturated fat are essential for growth
in babies and children, especially when it comes to brain
development. 134

The benefits of saturated fats clearly illustrate their importance.

137
Saturated fats are very stable and do not oxidize when used in
cooking at high temperatures. 135

However, the oils most of us tend to use are polyunsaturated (canola,


soy, corn, safflower, and sunflower).

These oxidize when used for high heat cooking, creating harmful free
radicals in the process.

Saturated fats play many vital roles in the body, such as helping to
strengthen the immune system, promoting healthy bones, protecting
the liver, and providing structural integrity to the cells.

After all, saturated fatty acids make up at least half of your cell
membranes.

Moreover, short- and medium-chain fatty acids inherent in saturated


fats like coconut oils have important antimicrobial properties.

Saturated Fat Daily Intake

As of 2010, the U.S. Department of Agriculture's (USDA) dietary


guidelines call for reducing your saturated fat intake to a mere 10
percent of total calories, which I believe is low if you want to maintain
optimal health.

138
My Recommendation Regarding saturated fat intake

Students, I am an educator and not an enforcer. If you are still unsure


whether you should consume saturated fats, then it's a good thing.
Do your research and come to your own conclusion.

However, if I have managed to convince you a little, it's ok to start


including some foods high in saturated fats, such as ghee, coconut oil,
etc., in your diet and keep track of your health data.

My diet averages ~30% of calories from dietary fats if I talk about my


diet. I cook all my meals in ghee or coconut oil. I drink whole milk and
consume only whole eggs.

My main objective with this course is to bust the myths, bring forth
the evidence, and my own experience with a particular food or a
nutrition concept.

In conclusion, saturated fat is vital for the human body to function


properly and should not be neglected.

Let's discuss another important myth and shed some light on the use
of vegetable oils.

139
M5: Nutrition Myths & Facts

L3: Myth #3: Cooking in Vegetables Oils is Healthy

P olyunsaturated fats are further divided into omega-6 and

omega-3 fatty acids.

The most common omega-6 is linoleic acid, an essential amino acid


that the body cannot manufacture on its own.

Even though Omega-6 polyunsaturated fats are essential to us, they


may pose health issues when eaten in excess. It's crucial to maintain
a ratio of omega-6 to omega-3 of 1-1 to a maximum of 4:1 for
optimal health.

The ratio of omega-3 vs. omega-6 is an advanced topic that is outside


the scope of this course but know this:
Today's modern diet has a highly skewed ratio of 20:1 or more. This
skewed ratio can trigger chronic inflammation and increase the
production of free radicals in our bodies.

Soybean oil is the most commonly used vegetable oil around the
world.

140
The other types of vegetable oils are sunflower, cottonseed, sesame,
canola, rice bran, grapeseed, and so forth.

These vegetable oils undergo a lot of processing before humans can


consume them.

Most commercially available vegetable oils are converted from their


respective plant seeds using chemical solvents to make them edible.
136

There are more than a dozen steps in extracting oils from their
respective seeds on average! Besides containing many chemical
solvents, most vegetable oils are very high in Omega-6 fatty acids.

Omega-6 has many carbon double bonds, making them highly


reactive and sensitive to heat, oxygen, and light. They can get easily
oxidized and turn into free radicals.

Free radicals can trigger diseases by altering proteins, lipids, DNA,


and cell membrane integrity. 137, 138

Scores of scientific studies suggest that omega-6 promotes free


radical production and chronic inflammation. 139, 140, 141, 142, 143, 144

The common symptoms of chronic inflammation are body pain and


aches, fatigue, frequent gas, bloating, constipation, unwanted weight
gain, frequent infections like fever, ulcers, mouth sores, anxiety, and
even depression.

141
Stress, obesity, alcohol, smoking, excessive junk food consumption,
and eating foods high in omega-6 that disrupt the omega-6 and
omega-3 ratios are a few critical factors that cause chronic
inflammation.

Therefore, you must increase your consumption of omega-3s and


decrease the consumption of omega-6s. The easiest way to do the
latter is to stop using vegetable oils for cooking your food.

And replace these oils with ghee, coconut oil, extra-virgin olive, or
avocado oil, which are excellent fat sources in which you should
seriously consider cooking your meals.

In the next lecture, I'll try and bust another prevalent myth about egg
yolk and cholesterol.

142
M5: Nutrition Myths & Facts

L4: Myth #4: Egg Yolks Raise Cholesterol Levels

P aranoia from eating eggs boils down to this fact:

Eating whole eggs raises cholesterol.

According to conventional wisdom, cholesterol is bad for you.

It causes coronary heart disease. Therefore the American Heart


Association recommends1 limiting dietary cholesterol intake to <300
mg/d. 145

One medium egg has about 185mg of cholesterol, and if you eat two
whole eggs, you have already crossed that limit!

So, eating less or no eggs (or just the white portion) will not cause
increased cholesterol, and you will largely reduce the chances of
having coronary heart disease.

Right?

Well, let's find out.

143
First, some anecdotal experience: I have been eating eggs for many
decades now.

If I average my egg consumption in the last twenty years, it won't be


an exaggeration that I have consumed at least two eggs (including
the yolk, of course) daily!

In fact, in the past five years, my egg consumption would easily touch
about 30-40 eggs per week.

What has allowed me to fearlessly eat these many eggs every day
when everyone around me throws away the yolk or even completely
replaces omelets with cornflakes?

It's the power of science, and fortunately, there is enough evidence


for me to put a strong argument here.

Eggs and Cholesterol

Without cholesterol, we won't exist. It's found in every cell of our


body. Cholesterol is also a precursor hormone to testosterone,
estrogen, and cortisone.

Your liver makes about 75 percent of your body's cholesterol.


Just think, why would your body manufacture something that will
harm itself?

If you eat more cholesterol from dietary sources like eggs, your body
produces less of it. In the end, your body has the innate wisdom to

144
balance out its cholesterol levels based on your level of dietary
consumption.

According to these studies, egg consumption increases HDL.


Prospective epidemiological surveys5 (in the last 30 years or so) of
CHD risk have consistently found no independent relationship
between dietary cholesterol or egg consumption and CHD risk.
(Dietary cholesterol and atherosclerosis.) 146, 147, 148

The Nurses' Health Study (1980—1994) and the Health


Professionals Follow-up Study (1986—1994), totaling over 1 million
subjects (A prospective study of egg consumption and risk of
cardiovascular disease in men and women.) could not find any
significant difference in cardiovascular risk between groups
consuming less than one egg per day and those consuming more
than one egg per day. 149

Bottom line, consumption of whole eggs raises your HDL cholesterol


& does not contribute to coronary heart disease.

Is Egg Good For Health?

Yes! A high-quality egg from pasture-raised hens is one of the most


nutritious foods you can eat.

In addition to providing high-quality proteins, healthy fats, and


almost all vitamins and minerals, it also provides special nutrients for
eye health.

145
Lutein and zeaxanthin are antioxidants that are very beneficial for eye
health. 150

Many studies qualify and support lutein's favorable effects on eye


health.

According to the American Optometric Association:

Lutein and zeaxanthin filter harmful high-energy blue wavelengths of


light and help protect and maintain healthy cells in the eyes. Of the
600 carotenoids found in nature, only these two are deposited in high
quantities in the retina (macula) of the eye. 151

Besides eating eggs, these two nutrients are abundantly found in


kale, spinach, collards, turnip greens, green peas, and broccoli.

Conclusion: How Many Eggs Can I Eat In A Day?

Based on my anecdotal experience, and scores of solid scientific


evidence, I can confidently say that you can eat about 3 whole eggs
per day.

146
M5: Nutrition Myths & Facts

L5: Myth #5: Potatoes are Fattening

V egetables that grow underground on the root of the plant are

called tubers. The most common tubers we all eat regularly are
potatoes.

Potatoes are high in carbs, and that's why people worry that eating
them will make them fat.

A medium potato (150g) provides more potassium than a banana and


around 30% of the daily value of vitamin C (provided you don't peel
it).

Even if you peel it, there is a minor loss of these nutrients, which is
acceptable! It has zero fat, moderate protein of 3g, 2g fiber, and 26g
of carbs! It is tasty, affordable, and versatile.

Athletes love this food, primarily as a performance food, because of


its high GI and potassium levels.

Potassium is an electrolyte essential for muscle functioning. Since


potassium is lost in sweat, it needs to be replenished for optimal
performance, especially for endurance athletes!

147
Potatoes also have iron, vitamin B-6, manganese, magnesium,
phosphorus, and niacin.

This nutrient profile makes it a pretty good food nutrient-wise.

Potatoes' GI value is high, and therefore I advise caution for people


with blood-sugar issues to absolutely limit their potato quantity to a
minimum.

It's also a good idea to eat potatoes with other high protein and fatty
foods to lower its overall GI value unless you are an athlete and
eating potatoes as a pre-workout snack to fuel your energy needs
quickly!

So basically, for just 100 calories, you are getting more potassium
than a banana. In addition, you are ingesting vitamin C, iron, vitamin
B-6, manganese, magnesium, phosphorus, niacin, and some folate!

Potatoes of all varieties are super tasty and affordable for most when
eaten by simply boiling it and adding some spices to make it tasty.

However, the problem starts when we prepare and consume it in the


form of french fries and potato chips.

French fries are fried in vegetable oils, potato chips are highly
processed, especially if you buy them from the market!

So the answer to the question; does eating potatoes make you fat?

No, eating potatoes does not make you fat. Regularly eating potato
chips and french fries will make you fat!

Also, eating more than you can burn and not being consistent with
your workout makes you fat!

148
M5: Nutrition Myths & Facts

L6: Fact #1: Diets Fail | What You Need Is A Lifestyle


Change

M ost diets fail. Dieting just doesn't work.

According to the New York Times, ‘Ninety-five percent of people who


lose weight on a diet gain it back, and a significant percentage of
people gain back more than they had originally lost,’ just like in less
than a year or two, almost everyone who wins the lottery is worse off
than before they won it! 152

Moreover, ninety-two percent of people give up their New Year's


Resolutions of losing weight and becoming healthier!

These statistics are dismal.

Instead, what is required is a lifestyle change.

You see, most diets are restrictive and inflexible. This makes them not
sustainable.

149
They believe that to lose weight, it's normal to give up their favorite
foods altogether, eat a severely calorie-restrictive diet, and focus on
specific so-called 'fat loss' foods that can help lose the flab.

What happens after a month or so: they do indeed lose a lot of


weight but at a cost.

Because they were under a severe caloric restriction, two things


happened:

They lose a lot of lean muscle, as the weighing scale was going down
effortlessly without exercise, and they think there is no need to work
out.

Anyways, it's not easy to work out by eating fewer calories.

Their metabolism shuts down because of calorie deprivation, and


cravings and hunger start to build up.

Not good.

And now that they have managed to lose a lot of weight (even
though they don't look healthy, toned, or sexy as without gaining any
lean muscle, you really cannot shape your body), they still think it's a
victory and deserve a treat.

The treat would not be broccoli.

Instead, they go out with their friends and family and binge on a
delicious pizza, a medium coke, and large fries.

150
At this time, their body's metabolism is damaged and is primed to
gain fat.

Most of the calories will go towards fat storage.

When you deprive and restrict food for that long, the body thinks a
famine is coming, and it's better to store calories in case it hits again.

Excellent, now all 1000 + calories you had in your pizza and coke and
fries goes towards your gut, all fat.

This cycle repeats itself. You start to feel guilty, craving increasing as
it's a cry of nutrients required by your body, but junk and fast food
have only empty calories in them.

To mention it again: The majority of people who lose weight on a


diet gain it all back within a year of dieting, and most of them gain
back more than they had originally lost.

The bottom line, stop dieting; it does not work. Instead, aim to build
lifestyle habits.

151
M5: Nutrition Myths & Facts

L7: Fact #2: Refined Carbohydrates and Added Sugar


Are Bad For You

A dded sugar in foods and refined sugar were non-existent a

few hundred years ago!

Did you know that when refined sugar was created, it was considered
healthy? Only the elite class could afford it.

In the 1700s, sugar consumption was only 4 pounds per annum. It


increased to 60 pounds per annum in the 1900s.

In the 21st century, the average worldwide sugar consumption per


annum is a whopping 170 pounds per annum!

In fact, added sugar is present in ~75% of processed foods and


beverages in the United States. And the reality is no different
globally.

Almost every nutrition expert agrees that refined carbohydrates like


white bread, pastries, doughnuts, flour, literally any carbs which are
processed are bad for you.

152
All that you are left with is the starchy part, which, when consumed,
spikes your insulin and ultimately causes insulin resistance leading to
a host of chronic diseases. 153

Sugar is literally added to almost every processed food item you find
in your favorite supermarket.

If a food item is in a box or a wrapper, you bet it will have some


added sugar in disguised form.

Sugar has various forms, and most of us eat these processed foods
without even knowing just how much sugar we are consuming.

It's interesting to note that a large percentage of calories from added


sugar comes from soda, juices, and other sugary drinks. To be precise,
SSBs (Sugar-sweetened beverages) account for more than one-third
of the calories from added sugars.

A recent review of 30 studies (none of them SSB


industry-sponsored), concluded that sugar-sweetened beverages are
associated with weight gain and obesity. 154

A total of 244,651 participants were included in this review. Of the


30 studies, 20 studies were conducted on children!

Scores of scientific literature indicate that the consumption of SSBs


causes insulin resistance. 155, 156

Insulin resistance significantly increases the risk of having type-2


diabetes.

153
A 2014 meta-analysis by Bo Xi et al. titled: Intake of Fruit Juice and
Incidence of Type-2 diabetes aimed to estimate the link between
sugar-sweetened fruit juice intake and risk of type-2 diabetes.

The meta-analysis of four studies included a total of 191,686


participants. It concluded that a higher intake of sugar-sweetened
fruit juice significantly increased the risk of developing type-2
diabetes. 157

Excessive sugar can also cause tooth decay and other dental
problems. Furthermore, excess consumption of refined carbohydrates
and added sugars can increase the risk of various chronic diseases.

Sugar is addictive. It's a mighty enemy. It's virtually impossible to


eliminate it.

However, it's possible to limit its consumption by choosing healthier


food options, including and not limited to vegetables, whole grains,
and eating most of your meals at home; a person can lose a lot of
weight and enjoy good health.

Let's discuss Nutrition fact #3 in the next lecture.

154
M5: Nutrition Myths & Facts

L8: Fact #3: Supplements Can Never Completely


Replace Your Diet

T he food that we eat is indeed losing its nutritional value: the

way it's grown, transported, and how we store it and cook it.

Unless you buy your produce from a local farmers market and take
every precaution to store it effectively and consume it by cooking on
medium heat and not overcooking it, there is almost a loss of close to
50-70% of nutrients in your food.

There is another issue. 60% of the calories come from processed


foods for Americans. The reality is no different than in the rest of the
world.

Factory foods are highly processed and offer very little or no


nutritional value.

It's straightforward.

The companies that manufacture these processed and fast foods rely
on taste and convenience and obviously on how much profits they'll
earn by the end of the day.

155
And that's why I think dietary supplements are necessary, but they
can never completely replace a good balanced nutritious diet.

I understand that no one likes to eat veggies, but do you know that so
many phytonutrients compounds still haven't been discovered yet? 158

Supplements don't provide that.

Eating a balanced diet with most calories coming from unprocessed


foods like fruits, vegetables, whole grains, quality protein like eggs,
raw dairy, nuts, seeds, coconut oil, and so forth is very important, and
no pill can ever replace this.

156
M5: Nutrition Facts & Myths

L9: Fact #4: Eating More Fruits And Vegetables Is


Good For Your Health

A s we discovered in the module titled: Micronutrients, just how

important it is to get all the essential vitamins and trace minerals as


the human body cannot manufacture them independently.

You realize how vital they are and the critical role they play in keeping
us alive.

Fruits and vegetables are the single most significant source of these
micronutrients.

Now, I get it; it's hard work to consume 5-8 servings of fresh fruits
and vegetables every day!

To go to the grocery store, buy the fruits and vegetables, which are
more expensive than a McDonald's burger, and then they don't even
taste that good.

Students, it's developing a perspective and a long-term mindset.

157
Fruits and vegetables are essential, and if you eat enough every day,
you are giving the body nutrients that will keep you optimally
healthy. You have to do the work and believe that it will pay off
long-term.

That's the only way.

Being good at making salads makes it a habit to include some


veggies with every meal you eat, add various colors of veggies, and
green leafy is the most important.

Try and ferment your vegetables for probiotics. And needless to say,
veggies are also the most significant source of fiber.

Fiber and probiotics are two nutrients that most people are severely
deficient in.

158
M5: Nutrition Facts & Myths

L10: Fact #5: There Is No Perfect Diet For Everyone

I full-heartedly believe in this statement.

We all thrive on different foods; we eat foods based on our culture,


upbringing, preference, and lifestyle.

Just because the keto diet is a rave now does not mean you will also
get great results. You may or may not. A cookie-cutter diet plan may
not work for you.

You need to find or create a diet for yourself and your clients (if you
plan to become a nutrition coach) according to their unique needs,
including their culture, preferences, and overall lifestyle.

Do check out an article titled: Best Diet, which you can find on my
website, to learn more about this topic.

This is a wrap for this module, and the last and final module is about
Superfoods. It will be an in-depth module where I will discuss dozens
of superfoods that one should include in their diet regularly.

159
M6: Superfoods

L1: Superfoods: Fruits: An Introduction

F ruits, along with fructose (which is the natural sugar found in

fruits), have vitamins, minerals, phytonutrients, and fiber in them.

When it comes to the macronutrient content of any typical fruit, more


than 95% of calories are from simple carbohydrates with very little
protein and virtually no fat.

Therefore, when discussing fruits, there are a few critical questions


we should ask ourselves:

1) Which fruit(s) have the lowest sugar content (fructose) in them?

2) Which fruit has the highest fiber content per 100g?

3) What are the top 3 choices of fruits that one can consume
regularly?

160
The answer to the first question will vary based on two factors:

1) How active are you?

2) Do you have any blood-sugar-related issues?

I am NOT a medical doctor. Therefore, I cannot answer the latter


question, but as an educator, I can surely provide the basic science to
get you thinking.

We already know that carbohydrates are classified as simple or


complex.

The simplest of sugars are glucose and fructose. Every cell of your
body can use glucose.

Glucose straight away goes into your blood, where it is picked up by


the hormone insulin and directed into the cells all over the body.

However, none of our body cells can metabolize fructose, so it goes


straight to your liver. Only the liver can metabolize fructose. 159

Our liver can store ~100g of glycogen, and our muscles can store
~400g of glycogen. This may vary from person to person.

What happens when your glycogen stores are almost full because
you have not been working out?

161
Or perhaps you have been eating a lot lately. In that case, a large
percentage of fructose coming to your liver now gets converted into
fat.

This is because there is no need for energy.

As more and more fat is stored in and around your liver, you start to
develop a condition called non-alcoholic fatty liver.

This is the visceral fat—the fat surrounding your organs and is


different from the subcutaneous fat stored beneath your skin.

Fatty liver is a medical condition that can increase bad cholesterol


and decrease your good cholesterol. In addition, it can raise
triglyceride levels.

Fatty liver can also cause insulin resistance, increasing the chance of
developing type-2 diabetes. 160

Bottom line, when you deplete your glycogen stores in the liver and
your muscles with regular workouts, fasting, and eating a calorie
deficit diet, the fructose that goes to your liver mostly gets converted
into glucose and lactate to be used for energy.

But when there are no energy needs, the liver has no choice but to
convert the fructose into visceral fat.

Therefore, I advise limiting your fruit intake for people suffering from
blood-sugar-related issues and living an overall sedentary lifestyle.

162
Find a chart in the resource manual that will give you a brief idea of
your fruit consumption.

Starting with the next lecture, let's categorize fruits based on their
nutrient profile.

Of all the fruits, berries contain the lowest sugar per 100g.

Let's discuss berries in the following lecture.

163
M6: Superfoods

L2: Superfoods: Fruits: Berries

B erries are a dietary source of multiple compounds and

nutrients, including flavonols, vitamins, and fiber, which help boost


heart health and reduce CVD risk.

Many studies indicate that regular consumption of berries may play a


role in preventing cardiovascular disease. 161, 162, 163, 164

A study led by researchers from the Harvard School of Public Health


(HSPH) finds that women who eat three or more servings of
blueberries and strawberries each week may lower their risk of
having a heart attack. 165

Research suggests that berries like blueberries, raspberries,


blackberries, and strawberries are rich in dietary fiber, vitamin C,
magnesium, antioxidants, and protective plant compounds like
anthocyanins and polyphenols.

And all these play an essential role in a cancer-protective diet. And


its consumption may protect from chemotherapy-associated toxicities
of cancer too. 166, 167, 168, 169

164
Berries, such as bilberry and black currant extracts, chokeberry juice,
cranberry extracts, and freeze-dried strawberries, are shown to
positively affect plasma glucose in studies with subjects with risk
factors including type-1 or type-2 diabetes mellitus. 170

Berries have a low glycemic index and load, so they don't raise blood
sugar levels as much as other fruits.

The fiber and anthocyanins block certain digestive enzymes to slow


down digestion, preventing spikes in blood sugar after eating high
carbohydrate foods. 171

More studies suggest that dietary berry extracts can protect against
and even reverse specific age-induced declines in brain function, such
as learning motor performances and delay the development of
age-related neurodegenerative diseases. 172, 173

Here are some of the specific benefits that may accrue when you eat
the following berries:

Blueberries may help protect from cancer, heart disease, diabetes,


dementia and boost the immune system.

Acai berries may help reduce blood cholesterol oxidative stress and
even reduce osteoarthritis symptoms.

Blackberries may assist in reducing the factors responsible for heart


disease and cancer.

165
Strawberries may help lower high blood pressure and cholesterol,
control blood sugar, and fight the effects of aging on the brain.

Goji Berries have been part of Chinese medicine for thousands of


years. They boost immunity, fight heart disease, help the brain, aid
digestion, improve eye health, and prevent cancer.

Cranberries are a sour superfood and are consumed mostly as juice


and may lower the risk of urinary tract infection (UTI), the prevention
of certain types of cancer, a better immune system, and decreased
blood pressure.

Red Raspberries may help fight different cancer types and protect
the brain.

Gooseberries or amla can treat colds and fever, help digest food, and
is used as a hair tonic.

Berries are available in different colors, having entirely different


nutrient profiles. So the best way is to mix the berries and include
them a few times a week in the diet.

Now, to answer the second question: Which fruit has the highest
fiber content?

It's avocados. Let's discuss this green fruit in the next lecture.

166
M6: Superfoods

L3: Superfoods: Fruits: Avocados

A vocado is a medium-sized fruit with a pleasant, creamy and

smooth texture.

They grow in warm climates and come in various colors, ranging from
pale green to almost black when fully ripe. The most popular kind is
Hass avocado, which is round with black skin.

Avocados are a source of vitamins C, E, K, and B6 and riboflavin,


niacin, folate, pantothenic acid, magnesium, and potassium. 174

Carbohydrates in avocados contain about 80% dietary fiber,


consisting of 70% insoluble and 30% soluble fiber.

The soluble fiber dissolves into a gel-like substance that binds to


fatty acids to assist in their excretion and boost healthy cholesterol
levels.

In addition, the insoluble fiber in avocados increases stool size and


hastens material movement through the intestinal tract. 175

167
Avocados are high in fat but it's monounsaturated fat, which is good,
which helps lower bad cholesterol.

100g of avocado will provide 7g of fiber which is the highest for any
fruit.

Most fruits provide anything between 2-4g of fiber per 100g.

Eight preliminary clinical studies concluded that avocado


consumption helps support cardiovascular health. In addition,
experimental studies suggest that avocados may also support weight
management and healthy aging.176

Avocados contain many carotenoids, such as lutein and zeaxanthin,


essential for eye health and reducing the risk of age-related eye
diseases. 177, 178

Overall, avocados are a nutrient-dense fruit that offers a wide variety


of nutrients and phytochemicals and can regularly be included in
one's diet.

Let's discuss the remaining most popular fruits eaten globally in the
next lecture.

168
M6: Superfoods

L4: Superfoods: Fruits: Other Superfruits

I t's a good idea to eat fresh, local and seasonal fruits. Try and

include a few units of fruits on a daily basis if you are a healthy & and
active adult.

Furthermore, prioritize fruits with little sugar, like berries and


avocados.

In this lecture, I'll discuss a few more fruits that are not only nutritious
but are affordable and readily available globally.

Let's start with papaya's.

Papayas

Christopher Columbus called papaya "the fruit of the angels" because


it tasted so good.

Papaya is a good source of carbohydrates, fiber, vitamin C, A, B9 and


is rich in carotenoids, an antioxidant.

169
These antioxidants are better absorbed from papaya than any other
fruit or vegetable. 179

It also contains an enzyme called papain, that is used to tenderize


meat.

More benefits of papaya are that it reduces oxidative stress. 180

A study conducted on a group of older adults showed that papaya


was able to reduce the symptoms of pre-diabetes, hypothyroidism,
and liver disease. This reduction of oxidative stress has been
attributed to lycopene, a carotenoid that removes excess iron from
our bodies. 181, 182

Papaya has anti-cancer properties, reduces inflammation, and has


been shown to improve heart health due to the presence of vitamin C
and lycopene.

In addition, it boosts the production of HDL, which is "good"


cholesterol for our body.

The enzyme papain is proven to boost metabolism and improve


digestion. In fact, in the tropical tribal areas, papaya is considered a
cure for Irritable Bowel Syndrome (IBS). 183

It also improves skin health. A lot of women include papaya in their


homemade face masks. It tightens the skin and lessens the effects of
aging.

170
Banana

Banana could be the perfect food for kickstarting your day as it has a
high mineral content and easily digestible carbs.

It is not only readily available, but it is also very versatile as it can be


consumed as is or cooked with oats, blended in smoothies or be a
part of a salad.

They have a wide range of health benefits, including some


antioxidant properties.

Bananas are full of potassium. A potassium-rich diet is connected to


lower blood pressure, which reduces the risk of heart disease and
stroke. 184

Bananas also have a decent amount of magnesium to help with heart


health.

The GI index of a ripe banana is 51, which falls under the medium GI
value. This implies that people with blood-sugar issues should eat
bananas in moderation.

Many studies say fiber intake from vegetables and fruits like bananas
positively affects weight loss. 185, 186

Moreover, a banana's sweet taste makes it a fantastic food for weight


loss as its taste helps satisfy cravings for sweets.

171
Bananas have relatively few calories. For example, a medium-sized
banana has just over 100 calories.

And I personally include a banana in my protein smoothie daily.

Apple

Apples contain vitamin C, vitamin E, potassium, and a wide variety of


antioxidants.

They can improve lung strength, heart health, bone health, and brain
health by reducing symptoms of Alzheimer's disease and age-related
memory loss.

They may also boost the immune system, improve gut health, and
relieve asthma symptoms. 187

Apples possess various phytonutrients that exhibit beneficial effects


on cancer, asthma, pulmonary dysfunction, cardiovascular diseases,
Alzheimer's disease, the decline of normal aging, weight, and
diabetes.

Apples are a good source of antioxidants and beta-carotene. Studies


show that consuming antioxidant-rich foods may help prevent
oxidative stress that causes cell damage, leading to certain cancers.
188

172
Apart from insoluble fiber, apples also have soluble fiber, such as
pectin, which helps prevent cholesterol from building up in blood
vessels' lining, preventing atherosclerosis and heart disease.

A study conducted in 2011 showed that women who ate about 75


grams (one-third cup) of dried apples every day for at least six
months had a 23% decrease in bad (LDL) cholesterol and a 4% rise in
good (HDL) cholesterol. 189, 190

Studies suggest that consuming whole fruits, particularly blueberries,


grapes, and apples, is significantly correlated with a lower risk of type
2 diabetes. 191

Consumption of fruits high in soluble and insoluble fiber like apples is


associated with improved glucose metabolism in diabetic and
nondiabetic individuals. 192

A word of caution: Apples are the most common fruit sprayed with
pesticides. Therefore it's a good idea to remove pesticide residue, dirt
and wax by soaking it in a solution of one teaspoon of baking soda
and two cups of water for 10 – 15 minutes, then rinse and wipe them
well.

While you can peel the apples before eating them, there will be a
loss of nutrients as two-thirds of the fiber and many antioxidants are
in the peel.

173
Mango

By production, mango is the world's fifth-largest fruit crop behind


bananas, grapes, apples, and oranges. It is one of the most important
and widely cultivated fruits of the tropical world.

Mango is low in calories, cholesterol-free, high in fiber, and a good


source of vitamins and minerals, including vitamins C, A, E, and K,
and a range of B vitamins. It also contains many polyphenolic
compounds.

The polyphenolic compounds in mango exhibit high antioxidative


activity that protects the body against damage linked to oxidative
stress.

Mango has about a dozen types of these compounds, including


mangiferin, catechins, anthocyanins, quercetin, kaempferol,
rhamnetin, benzoic acid, etc.

Quercetin is the main flavonoid in mango. Quercetin exhibits


anti-cancer, anti-inflammatory, and antihistamine effects and
prevents oxidative damage to the body. 193, 194

Mango contains magnesium and potassium, promoting lower blood


pressure and arterial function, reducing heart disease risk.

Increasing potassium and decreasing sodium in the diet are among


the most important dietary changes people can make to reduce high
blood pressure risk.

174
Mango is a delicious, readily available, low-priced fruit, rich in
vitamins, minerals, and antioxidants and can provide many health
benefits.

But yes, it contains more sugar than most fruits; one should enjoy
mangoes in moderation.

Final Thoughts

To summarize, fruits are a great addition to one's diet. However, it's a


good idea to proceed with caution and limit one's portion sizes when
consuming them.

Even though they are nutrient-dense and are loaded with vitamins,
minerals, fiber, and contain thousands of phytochemicals and other
beneficial compounds, they also contain fructose, a type of sugar.

A few hundred calories from fruits are acceptable in normal healthy


adults who work out regularly.

However, if you have blood-sugar-related issues, please consult your


physician regarding your fruit intake.

Let's discuss the next category of superfoods, vegetables.

175
M6: Superfoods

L5: Superfoods: Vegetables: Garlic, Onions & Ginger

V egetables (both cooked & raw) provide our body with

vitamins, minerals, fiber, and phytonutrients. Virtually every health


authority recommends at least 5 to 6 servings daily.

To achieve this daily quota, one must eat at least a big bowl of salads
with two meals.

In addition, further emphasis should be given to eating a significant


amount of cruciferous & green vegetables almost daily.

Let's start with the three most widely used superfood vegetables:
Garlic, onion and ginger.

Garlic and onion belong to the allium family.

Allium vegetables contain sulfur-rich compounds and may be


beneficial in lowering inflammation and blood pressure and help
prevent some types of cancer.

Let's start by discussing garlic & onions.

176
Garlic & Onions

Humans have used garlic for thousands of years as a flavor enhancer


and as a medicine throughout history.

Botanically, garlic is a vegetable; however, it is used more like a herb


to add flavor.

Garlic is known for its strong yet pungent taste.

Allicin, a sulfur-containing compound, is responsible for its unique


taste. Do note; allicin is only produced when you cut or crush the
garlic. 195

I am really amazed to see what raw garlic can do to your cold or flu.

Whenever I have a cold or flu, I chew raw crushed garlic cloves, and I
get better in a day or two.

This is because crushed raw garlic has the maximum allicin content,
as cooking can significantly reduce this sulfur-containing compound.
196

Allicin is known to boost one's immune system. 197

A few studies also support the fact that garlic is an excellent natural
remedy for cold or flu. 198, 199

177
Garlic is loaded with manganese, vitamin B6, vitamin C and selenium.
Garlic also helps in lowering blood sugar. 200

It also helps reduce cholesterol levels and can help prevent


Alzheimer's disease and dementia. 201, 202

Ways to include garlic in your diet:

The best way to include garlic is in its raw form. Make sure to crush or
chop it into small pieces before adding it to your salads or sauces.

Onions

Ever since I learned the advantages of consuming onions every day, I


have stopped minding the waterfall of tears while cutting them!

Onions like garlic are a member of the allium family.

It contains antioxidants, chromium, and vitamin A & C, among other


nutrients.

Like all non-starchy vegetables, onions are low in calories but


nutrient-dense.

The phytochemicals in onions help improve immunity, reduce


inflammation and heal infections. 203

It contains chromium that assists in regulating blood sugar.

178
Raw onion also helps lower the LDL (bad) cholesterol levels in our
body. 204

Regular consumption of onions has been shown to reduce the risk of


cancer, cataract, DNA damage, vascular and heart diseases.

Quercetin, a compound in onions, has anti-carcinogenic properties. It


prevents the spread of cancer nodes throughout the body.

How to add onions to your diet:

Include them raw as part of your salad or saute it with garlic for
cooking your vegetables or omelet.

Ginger

Ginger has a long history of use in traditional and alternative


medicine.

It has been used by Veds (a name given to Ayurveda /natural


medicine doctors) to help people with digestive issues, fight flu and
common colds etc.

Gingerol is the main compound in ginger, responsible for its medicinal


properties. It is an antioxidant and can significantly reduce the
production of free radicals in our bodies. 205

It is also a natural remedy for nausea. 206, 207

179
Including ginger in your diet can help prevent age-related brain
function decline and reduce the risk of certain types of cancer. 208, 209

Ways to include ginger in your diet:

The best way to include ginger is to have ginger tea and include it as
part of your cooking process.

Let's learn about cruciferous vegetables in the following lecture.

180
M6: Superfoods

L6: Superfoods: Vegetables: Cruciferous Vegetables

T he name "cruciferous" is an informal classification for the

mustard family members and comes from the Latin Cruciferae,


meaning "cross-bearing" because the plant's four petals resemble a
cross.

Cruciferous vegetables are rich in nutrients, including fiber, several


carotenoids like beta-carotene, lutein, zeaxanthin, vitamins C, E, and
K, folate, and minerals.

Their uniqueness comes from glucosinolates, a sulfur compound with


a bitter or spicy taste and intense aroma.

About 40 types of cruciferous vegetables are consumed worldwide,


however, we will talk about a few of the important ones.

Cabbage is low in calories and a good source of vitamins C and K,


magnesium, folate, and antioxidants. It is available in green and a
more nutrient-dense purple. It may help protect against radiation,
prevent cancer, and reduce heart disease risk.

181
Arugula or rocket leaves are rich in vitamins K and C, calcium,
nitrates, and polyphenols. They are a bit bitter and usually consumed
in salads and may help reduce the risk of cancer, osteoporosis, and
diabetes and improve heart health.

Broccoli is low in calories and a rich source of vitamins K and C,


folate, potassium, and antioxidants. Apart from cancer prevention,
broccoli may boost immunity, improve bone density, skin health, and
reduce inflammation.

Brussels sprouts are low in calories, a good protein source, a rich


source of calcium, antioxidant ALA, and vitamins K and C. Consuming
them may reduce the risk of certain cancers and diabetes and improve
bone and eye health.

Cauliflower is an excellent source of vitamins and phytochemicals.


Today it has become a popular low-calorie gluten-free alternative to
rice and flour. They are found in white, green, purple, and orange
varieties. Consuming it may strengthen bones, boost the
cardiovascular system, and help prevent cancer.

Collard greens are an excellent source of fiber, vitamin A, vitamin C,


and calcium, a rich source of vitamin K, iron, vitamin B-6, and
magnesium. They also contain several plant compounds and
antioxidants that help treat many ailments like cancer and diabetes
and help with a better digestive tract and healthy skin and hair.

Kale is a green leafy vegetable rich in dietary fiber, vitamins C and K,


calcium, iron, and antioxidants. It improves gut health and blood
pressure and protects against type 2 diabetes and cancer.

182
Radish is low in calories and rich in vitamin C and small amounts of B
vitamins, potassium, calcium, iron, and magnesium. In addition,
radishes contain natural sulfur-containing substances shown to
reduce inflammation and protect cells against cancer-causing agents;
they can be spherical, oblong, or cylindrical and have white, pink, or
purple flesh.

Watercress is an exotic dark leafy green that grows in natural spring


water. It is rich in minerals, vitamins, antioxidants, and nitrates. It aids
in preventing and treating cancer and diabetes, lowering blood
pressure, and improving bone health.

Bottomline, the nutrients and phytochemicals in cruciferous


vegetables, including fiber, potassium, folate, and isothiocyanates,
may help protect us against various medical problems like coronary
heart disease, cancer, the eyes, and reduce inflammation and the risk
of type 2 diabetes. 210, 211, 212, 213, 214, 215, 216

Let's discuss green leafy vegetables in the next lecture.

183
M6: Superfoods

L7: Superfoods: Vegetables: Green Leafy Vegetables

G reen leafy vegetables are low in calories, high in fiber,

vitamins, minerals and phytonutrients. Therefore, one should include


them in their diet on a daily basis for optimal health.

It's important to note that some of the cruciferous vegetables


discussed in the previous lectures can also be categorized as leafy
greens. A few examples are kale, collard greens and cabbage.

However, I have created a list of 9 leafy greens. Let's start with


spinach.

Spinach

Thanks to its impressive nutrient profile, spinach tops the chart as


one of the healthiest vegetables, consisting of various micronutrients
such as iron, manganese, zinc, and magnesium.

In addition, spinach leaves also contain small quantities of vitamin E,


A, C, K, folate, thiamine (B1), pyridoxine (B6) and riboflavin (B2).

184
Spinach leaves are high in insoluble fiber, which may boost health by
adding bulk to stool as food passes through the digestive system
and, in turn, prevent constipation.

Studies have found that dark green leafy vegetables like spinach are
high in beta-carotene and lutein, two types of antioxidants that may
reduce oxidative stress, preventing various chronic diseases like
cancer, diabetes and Alzheimer's. 217, 218, 219

Lutein and zeaxanthin, plant compounds in spinach, may promote eye


health. Various studies suggest these compounds protect us from
potential damage to the retina caused by sunlight and may reverse
existing damage to the eyes from cataracts and macular
degeneration. 220, 221

Among the vegetables, spinach is one of the highest sources of


dietary nitrate, and research shows that nitrates effectively lower
blood pressure. Adding spinach to the diet can be an effective way to
improve cardiovascular health. 222, 223

Beet greens

Beet greens are the leafy bits at the top of the beets and are an
excellent dietary source of fiber, packed with antioxidants, just like
the dark red tuberous part of the plant.

In addition, beet greens are rich in vitamins C, K, A and have zero fat
and cholesterol. They are also very high in iron, with a higher iron
count than spinach, magnesium, and potassium.

185
Beet greens are great for detoxifying the system and fighting
inflammation. Moreover, they boost heart health by regulating blood
pressure and improving blood flow. 224

Its edible leafy tops are rich in vitamin K, linked to a lower chance of
getting type 2 diabetes. Its vitamin A content is excellent for
maintaining a healthy vision and skin.

Vitamin C in beet greens helps a healthy immune system fight cold


and flu during winters. 225

Swiss Chard

The two main swiss chard varieties are rainbow chard, with
multicolored stems and veins and white stems and veins.

Both are excellent sources of lutein and zeaxanthin, an antioxidant


duo that's good for our eyes. 226

Swiss chard is low in calories but high in vitamins A, C, K,


manganese, and magnesium.

It is primarily known for its capability to prevent damage caused by


diabetes mellitus. An animal study suggested that chard extract was
found to reverse the effects of diabetes by decreasing blood sugar
levels and preventing cell damage from disease-causing free radicals.
227, 228

186
Asparagus

Asparagus, officially known as Asparagus officinalis, is a member of


the lily family. This famous spear-like spring vegetable comes in
various colors, including green, white and purple.

Asparagus is a rich source of folate, an essential vitamin for making


red blood cells and cell division. Just half a cup (90 grams) of
asparagus provides one-third of the daily folate needs. 229

Not only is asparagus rich in vitamins like vitamins C and E, but it also
contains plant compounds called polyphenols, all of which have
anti-inflammatory effects. 230

Lettuce

Lettuce is one of the most extensively consumed salad vegetables


worldwide; they are low in calories, fat and sodium. In addition, they
are a good source of fiber, iron, folate, and vitamins. C.

Lettuce contains bioactive compounds such as folate, β-carotene,


lutein, and phenolics. Studies have shown anti-inflammatory,
cholesterol-lowering, and anti-diabetic activities attributed to the
bioactive compounds in lettuce.

Their nutritional value significantly varies with lettuce types and leaf
color. Crisphead lettuce is comparatively low in minerals, vitamins,
and bioactive compounds, and the leaf type lettuce and romaine are
high in folate content comparable to other rich leafy vegetable
sources. 231, 232, 233

187
Wheatgrass

Wheatgrass is the young grass of a wheat plant. It is a thick, dry


grass that looks like hay or straw but is bright green. Farmers mainly
grow wheatgrass for animals to eat, but it has become popular as a
supplement and a superfood in recent years.

Wheatgrass is low in calories but rich in nutrients, including


antioxidants like chlorophyll, flavonoids, vitamin C, and E. The
antioxidants fight free radicals in our body, reduce oxidative stress
and protect against health conditions like arthritis, cancer, and
neurodegenerative diseases. 234, 235, 236, 237

Parsley

Parsley is a popular, valuable and essential medicinal herb with a


wide range of proven therapeutic activities.

There are two varieties of fresh parsley, curly leaf parsley is used as a
garnish, and flat-leaf parsley has a more robust flavor and is used
more regularly as an ingredient in salads and cooked dishes.

Parsley is rich in essential vitamins A, K, and C and other


antioxidants, which may help to reduce the risk of many health
conditions like diabetes, stroke, heart disease and cancer. 238, 239, 240

188
Cilantro

Cilantro, also known as coriander, is a herbal plant readily used in


cooking and alternative medicine.

Cilantro contains vitamins A, C, and K, and the leaves also have


folate, potassium, and manganese. All plant parts are edible, but
people most commonly use fresh leaves and dried seeds in cooking.

Researchers have found that cilantro may provide health benefits in


reducing the risk of heart disease, diabetes, obesity, and cancer and
raising energy levels and healthy hair and skin.

Many studies have connected eating cilantro with reduced symptoms


of cognitive diseases like Alzheimer's and Parkinson's disease. 241, 242,
243

Celery

Celery is a marshland plant from the same family as carrots and


parsley. Its crunchy, earthy and peppery stalks make the vegetable a
popular low-calorie snack, and it may provide a range of health
benefits. Although most people discard the leaves, they are also
edible.

Celery mainly consists of water but provides dietary fiber, which may
benefit the cardiovascular and digestive systems. Celery is a good
source of antioxidants that may play a role in preventing diseases like
cancer and Alzheimer's. 244, 245, 246

189
Each kind comes packed with phytonutrients, fiber, vitamins, and
minerals regardless of which green leaves you choose.

Therefore, it's imperative to include at least a few servings of these


green leafy vegetables in your diet daily.

We are still left with a few commonly consumed yet nutritious


vegetables. So let's discuss them in the following lecture.

Thanks for listening.

190
M6: Superfoods

L8: Superfoods: Vegetables: Other Vegetables

B esides vitamins, minerals and fiber, our bodies need

phytonutrients. While the discussion of phytonutrients is outside the


scope of this course, let me talk about them briefly.

Phytonutrients are chemicals plants produce to protect themselves


from insects, fungi, bugs, and UV rays.

These powerful compounds give the plants color, flavors, aromas,


and disease-fighting capabilities.

There are around 25,000 phytonutrients known to us.

Always think about a rainbow when formulating your diet.

Basically, 'Eat the rainbow' is a mantra that allows one to include


multiple foods with varying colors, including and not limited to red,
yellow, green, purple, orange and so forth.

Different color groups of fruits and vegetables have unique


phytonutrients and other nutrients that we require in abundance
almost on a daily basis.

191
So please remember: Always strive to consume a wide variety of
foods, especially local, fresh and seasonal fruits and vegetables.

With this thought in mind, let's discuss a few more nutrient-dense


vegetables that can easily be classified as superfoods.

Carrots

Carrots are a multi-nutritional food source that is sweet, tasty and


has excellent texture.

As their name suggests, carrots are rich in plant compounds called


carotenoids; they help maintain a well-functioning immune system,
skin health and support heart health. The absorption of nutrients is
better if the carrots are cooked. 247, 248

Carrots are a good source of antioxidants lutein and zeaxanthin, and


the duo may help prevent age-related macular degeneration, a type
of vision loss. 249

Carrots are very high in beta carotene and alpha-carotene, two


pro-vitamin A antioxidants that the body can convert into more
vitamin A, as and when needed. 250

Lycopene, a bright red antioxidant found in many red fruits and


vegetables, including red and purple carrots, lycopene may decrease
the risk of cancer and heart disease. 251, 252

192
We can enjoy carrots raw as a snack or in salads, cooked for soups
and sides or added to sweet bakes.

Beetroot

Beetroots, commonly known as beets, are vibrant, earthy, aromatic


food that grows underground.

They are low in calories but contain almost all the vitamins and
minerals our body needs. For example, a 200 gram serving of beet
contains just 85 calories and is loaded with folate, vitamin C,
manganese, phosphorus, iron, potassium, and magnesium.

It also contains inorganic nitrates that offer a lot of health benefits.

For example, a study recommends consuming high nitrate vegetables


like beetroot as an effective, low-cost way to help treat high blood
pressure as the nitrates in beets get converted to nitric oxide, which
aids in dilating blood vessels. 253

Beets contain an antioxidant called alpha-lipoic acid, and this


compound may help lower glucose levels and increase insulin
sensitivity. 254, 255

The best way to include this superfood is by adding it to your salad,


soup or stir fry. Also, beet leaves are healthy, so try adding them to
your vegetable juice or cooking them like spinach.

193
Cucumber

Cucumber is a rich source of valuable nutrients like vitamin B, K, C,


copper, potassium, manganese and other bioactive compounds. 256

Potassium, magnesium and dietary fiber in cucumber are known to


lower blood pressure, thus reducing the risk of heart diseases. 257

Cucumbers are believed to have anti-inflammatory benefits. When


applied to the skin, sliced cucumber has a cooling and soothing effect
and decreases swelling, irritation, and inflammation. 258

Cucumbers act as a coolant for the stomach. The soluble fiber in


cucumbers helps in slowing our digestion. Also, the high water
content in cucumber makes our stools soft, prevents constipation and
keeps our bowel movements regular. 259

We can enjoy them fresh in salads, pickled, or include them in our


juices.

Tomatoes

Did you know that tomato is the berry of a plant native to South
America? It is technically a fruit and not a vegetable.

It is rich in many antioxidants, vitamin C, vitamin K1, potassium, folate


and Vitamin K. It also contains 95% water and fiber.

According to studies, antioxidant lycopene in tomatoes may reduce


the risk of heart diseases and cancer. 260

194
Studies have found that dietary carotenoids in tomatoes may reduce
UV damage to the skin, lowering the risk to the skin from sunburn
and ultraviolet (UV) light-induced erythema. 261, 262

Tomatoes are beneficial for the skin due to the three high-powered
antioxidants, carotenoids, vitamin E, and vitamin C.

Tomatoes are generally described as a laxative fruit as they have high


water, fiber, and naringenin (a natural flavonoid) content. 263, 264

Tomatoes' fiber, potassium, vitamin C, lycopene, and choline support


heart health. Another compound, chlorogenic acid, has been
successful in lowering blood pressure. 265, 266

Peppers

You might not need a vitamin C supplement if you have a few bell
peppers in your refrigerator.

Bell peppers are classified as fruits and are found most commonly
red, green, yellow, or orange though some are mini peppers.

Bell peppers are among the richest sources of vitamin C, a


water-soluble vitamin known as ascorbic acid. The vitamin C in bell
peppers helps synthesize collagen, the most common protein found
in the body. Collagen is present in bones, ligaments, tendons, and
skin. 267

195
Bell peppers have a good amount of antioxidants, which may help
fight heart disease, prevent cancer, protect against liver disease and
combat oxidative stress and inflammation. 268, 269

Bell peppers are high in fiber and have a low glycemic index rating of
32, and studies have shown that low GI foods may result in reduced
blood sugar levels, weight loss, type 2 diabetes, and a lower risk of
heart diseases. 270

There is no shortage of recipes for bell peppers. One can have them
raw in salads, bake them, sauté them, stuff them, or even make
sauces or chutneys with them.

Eggplant

Eggplant is also known as brinjal or aubergine and is available in


purple, lavender, jade green, orange and yellow color. The most
popular variety of eggplant is a large, pear-shaped egg, hence the
American name 'eggplant.'

Although often considered a vegetable, they're technically a fruit, as


they grow from a flowering plant and contain seeds.

They are a source of vitamin C, vitamin K, magnesium, phosphorus,


copper, dietary fiber, folic acid, potassium, and manganese.

Eggplants are a rich source of anthocyanin compounds; besides


giving color, It has a significant role against diabetes, neuronal
problems, cardiovascular disorders, and cancer. 271

196
Eggplants are considered high in fiber and low in calories, making
them an excellent food for any weight loss routine. Fiber moves
slowly through the digestive tract and can promote fullness and
satiety, reducing calorie intake. 272

You can roast, bake, steam, or sauté eggplant. However, don't cut an
eggplant until you're ready to cook it, as it may result in a loss of
nutrients.

Mushrooms

Mushrooms have been part of our food culture for thousands of years
and are often addressed as "Food of the Gods.". They are available in
various shapes and colors and create savory, rich flavors called
‘umami.’

They're low in calories, fat, sodium and cholesterol-free, loaded with


minerals, fiber and vitamins.

They are a rich source of an antioxidant called selenium, which


protects our body from the radicals attributed to cancer, aging,
neurodegenerative and heart-related problems. 273, 274

Mushrooms are rich in all dietary fibers, especially beta-glucan. It has


been proven effective for improving cholesterol and boosting heart
health. 275, 276

197
Mushrooms are rich sources of potassium, a nutrient known for
reducing the negative impact that sodium can have on your body.
Potassium also lessens the tension in blood vessels, potentially
helping to lower blood pressure. 277, 278, 279

Mushrooms can be eaten raw, grilled, sautéd, or roasted. We can add


them to soups, sandwiches, wraps, casseroles, and Italian dishes.

Bitter gourd

Bitter gourd, bitter melon or karela is one the most bitter vegetables
no kid likes to eat.

Globally, alternative therapeutic and dietary approaches are


becoming famous for managing various health issues.

And recent research has shed light on the various health benefits of
bitter gourd seeds, fruits, leaves, and other plant parts.

Bitter gourd contains high amounts of vitamin C, vitamin A, vitamin E,


vitamins B 1, B2 and B3, vitamin B9 (folate), zinc, potassium and iron.

The bitter guard makes an excellent addition to a weight loss diet, as


it's low in calories yet high in fiber. 280

Bitter gourd fruit has antioxidant, anti-microbial, antiviral activities


and is a general traditional medicine in India and China. 281

198
Bitter gourd can be consumed raw but tastes better and less bitter
when steamed, stir-fried, braised, and stuffed in various nutritious
and delicious dishes.

Ok, students, this lecture marks the end of the vegetable section.

If you have gone through each of the lectures in detail, you have
probably realized the importance of eating a wide variety of fresh,
seasonal fruits and vegetables.

Strive to eat 8-10 servings of fruits and vegetables daily. You can
count cooked vegetables in this quota.

Let's now shift our focus to macronutrient superfoods. Let's start with
carbohydrates.

Thanks for listening.

199
M6: Superfoods

L9: Superfoods: Carbohydrates: Legumes

C arbohydrates have become a very controversial topic these

days. One side of the panel, primarily the paleo and ketogenic
advocates, advises against eating carbs because our ancestors didn't
eat them.

On the other side, some experts suggest there is nothing wrong with
carbs. Just go ahead.

In the next few lectures, I'll discuss superfoods high in carbohydrates


but still nutrient-dense.

Let's start by discussing legumes.

Legumes

Legumes are plants from the Fabaceae family, including the entirety
of the pods, stems, and leaves.

A pulse is the edible seeds of the legume plants. The three types of
pulses are beans, lentils, and peas.

200
We'll discuss dal (lentils) and beans in this lecture.

Dal usually refers to the split version of the lentils.

Depending on how difficult it is to dehusk and mill them, they can be


whole or split. A few examples of dal are green gram, pigeon peas,
red lentils, split black gram, etc.

Dal is an incredible protein source, especially for vegetarians. It is also


one of the cheapest to buy.

Given many vegetarians in India, it becomes imperative to include dal


in our diets to meet our protein needs.

Besides protein, lentils or dal are high in complex carbohydrates and


fiber. They also contain many vitamins and minerals.

Dals have been a staple part of our foods since times immemorial.

We can exploit this superfood to prepare healthy meals and, in turn,


contribute to a more sustainable environment as they have a low
carbon footprint, are water-efficient, are super affordable, and
improve the soil quality.

Beans also have a similar nutritional profile as that of dals.

They are packed with proteins, complex carbohydrates, B vitamins,


and minerals.

201
Besides their nutrients, beans offer incredible health benefits. They
help reduce the risk of developing metabolic syndrome, are
heart-healthy, help lower cholesterol, and promote gut health; the
list goes on and on.

Kidney beans (red and black) are a type of bean that is commonly
consumed globally.

As an example, a 100-gram serving of kidney beans provides a


moderate ~127 calories with around 9 grams of protein and 23
grams of complex carbohydrates, out of which ~6g is fiber and
virtually no fat.

Carbohydrates in legumes are ~25% fibrous and have a low glycemic


index (<30).

Most people are deficient in fiber, and including legumes (both dals
and beans) will help you optimize your fiber content.

In summary, whichever cuisine you follow, try and include at least a


few hundred grams of cooked legumes in your diet on a daily basis.

Let's discuss ‘oats’ in the next lecture.

202
M6: Superfoods

L10: Superfoods: Carbohydrates: Oats

O ats are a type of cereal grain from the Poaceae grass family.

Due to their many health benefits, like cholesterol and blood sugar
control, oats have gained enormous popularity.

Most people eat oats as oatmeal for their breakfast. However, many
prefer eating oatmeal bread, and some even include oats in their
smoothies!

Oats are a versatile grain, and hundreds of tasty recipes can be made
from them!

If you want a type of oats with the highest fiber content and the most
nutrient-dense with a low GI value, look no further than oat groats!

These are whole oats with only the inedible hulls removed!

However, they take at least 30-45 minutes to cook!

The type of oats that I consume is steel-cut oats.

203
Steel-cut oats are groats cut into several pieces with a steel blade.

This reduces cooking time to 20-25 minutes!

They take a little longer to cook than rolled oats, but their wonderful
and satisfying texture is worth the wait.

Rolled oats are the most common type of oats.

These are steamed, rolled, and flattened into flakes, then dried to
remove moisture to increase shelf life. Their average cooking time is
12-15 minutes.

Quick oats cook faster than the oats mentioned above. They are cut,
steamed, and rolled into thinner flakes.

Their finer texture is the reason they are a frequent ingredient in


muffins, cookies, and bread.

The average cooking time is approximately 5 minutes.

Lastly, you have instant variety.

You find these oats in a single serving packet, often with added
flavors.

They are pre-cooked, dried, cut, and rolled for instant


preparation—just add boiling water.

204
Do note, with more refining, processing, steaming, and cutting, the
nutrients in oats decrease.

There is a significant loss of vitamins, minerals, and fiber. Processing


and refining the oats also increases their GI value.

So if you want maximum goodness from this cereal grain, stick with
oat groats or the steel-cut variety.

Oats are a good source of beta-glucans, a type of soluble fiber.

Many studies have concluded that diets rich in beta-glucans reduce


LDL cholesterol. 282

Other health benefits of oats include and are not limited to a lowered
risk of heart disease and type-2 diabetes.

Oats are gluten-free, which makes them a viable choice for


gluten-intolerant people. 283

Let's discuss whole grains in the next lecture.

205
M6: Superfoods

L11: Superfoods: Carbohydrates: Other Whole Grains

W hole grains are high in complex carbohydrates, fiber,

vitamins, and minerals.

We have learned that whole grain is called a kernel, and it has three
layers: bran, germ, and endosperm.

Whole grains like whole wheat, brown rice, etc., retain all three
layers and therefore are nutrient-dense compared with refined grains.

The refining and polishing of the whole grain removes the bran, and
the germ layer produces refined grains like white rice and white
bread.

Refined grains have a finer texture and longer shelf life and are used
to make bakery products.

There are little or no nutrients and fiber in refined grains as it is


stripped off the germ and the bran layer leaving only the endosperm,
mostly starch. 284

206
Wheat, barley, and rye are three whole grains with gluten. If you are
gluten-intolerant, it's best to avoid these whole grains in any form
altogether.

If you are looking for gluten-free whole grains, look no further than
millets.

Millets are of 8 types, but the three most common ones are:

-Finger Millet (Ragi)


-Sorghum Millet (Jower)
-Pearl Millet (Bajra)

Millet was India's staple food about 4-5 decades back!

However, they have been sidelined in favor of wheat and rice even
since the Green Revolution.

Millets are a robust crop. They hardly require any pesticides to


survive, require a lot less water, and grow year-round.

They are coarse grains and packed with a lot of goodness!

Finger millet, sorghum, and pearl millets do not have an inedible husk
covering the grain. They can be cleaned and eaten.

Millets are high in complex carbohydrates, have moderate protein and


minimal fat. And they have the fiber goodness.

207
Quinoa

The list of superfoods cannot be complete without discussing quinoa.

Quinoa is a seed that comes from a plant indigenous to the region of


South America.

Technically, quinoa is a seed prepared and cooked as grains—That's


why they are called pseudo-cereals.

The other pseudo-cereals are buckwheat and amaranth.

Quinoa seeds come in various colors, including red, black, yellow, and
white.

Unlike other grains, quinoa is a complete protein. It contains all the


essential amino acids that our bodies need. It also has similar fiber
content to grains. 285

Quinoa is high in nutrients magnesium, manganese, folate, copper,


phosphorus, iron, zinc, and vitamins B1, B2 & B6.

And lastly, it's perfect for gluten-intolerant people.

To summarize this category of superfoods, aim to get most of your


calories from legumes- dals and beans.

It's ok to add whole grains to your diet but limit their portion sizes
and prioritize calories from legumes over whole grains.

208
If you are wondering about my take on rice and bread, please find the
article links in the resource section, where I have discussed these
foods in detail.

Now, let's discuss superfoods high in protein, starting with the next
lecture.

209
M6: Superfoods

L12: Superfoods: Proteins: Whole Eggs

P rotein is an essential macronutrient that our body needs for

growth and maintenance.

They are the building blocks of muscle tissue and serve as precursors
for nucleic acids, hormones, vitamins, and other integral molecules.
286

No doubt, protein as a macronutrient is essential and should be


consumed in adequate quantities on a daily basis, especially if you
are an active adult. 287

Let's learn about the top superfoods rich in proteins. I'll divide the
protein foods into four sections.

Let's begin with whole eggs.

Pasture-raised Eggs

Eggs are one of the most nutritious foods on the planet, provided you
opt for pasture-raised eggs or, at the very least, go for organic and
free-range eggs!

210
Recent science has cleared the air that dietary cholesterol is not
linked with heart disease. 288

And some studies have even proved that eggs can increase your
HDL, which is good cholesterol. 289, 290, 291

Without cholesterol, we won't exist. It's found in every cell of our


body. Cholesterol is also a precursor hormone to testosterone,
estrogen, and cortisone.

Your liver makes about 75 percent of your body's cholesterol.


Just think, why would your body manufacture something that will
harm itself?

If you eat more cholesterol from dietary sources like eggs, your body
produces less of it. In the end, your body has the innate wisdom to
balance out its cholesterol levels based on your level of dietary
consumption. 292, 293

A medium egg contains about 69 calories and 6 grams of


high-quality protein. 294

Besides high-quality protein, eggs have a lot of important


micronutrients that you should know about: One medium egg (50g)
contains varying amounts of 13 essential vitamins and minerals.

Whole eggs are loaded with the nutrient choline.

211
Choline has a variety of roles, including nervous system health, DNA
synthesis, fat transport and metabolism, brain, and memory
development. 295

A medium egg also contains about 5 grams of fat.

Eating healthy fats has a satiety effect. No cravings, no energy dip!

In addition to providing high-quality proteins and almost all vitamins


and minerals, it also offers particular nutrients for eye health.

Lutein and zeaxanthin are antioxidants that are very beneficial for eye
health. 296

Many studies qualify and support lutein's favorable effects on eye


health. 297

I don't know about you, but I still look forward to my egg breakfast
even after eating them for decades.

How to include eggs in your diet:

Eggs are so versatile, and you can whip them into whatever you
want—poached, soft-boils, sunny-side-up, omelets, scrambled.

Let's discuss grass-fed dairy and related products in the next lecture.

212
M6: Superfoods
L13: Superfoods: Proteins: Grass-fed Dairy:
Raw Milk, Buttermilk

R aw cow’s milk is an overlooked superfood. It’s called raw

because it is not pasteurized or homogenized.

I have been drinking raw cow's milk since I was a baby. My son is
eight years old now and has been fed raw cow’s milk since he was a
year old.

My parents, their parents, and generations before them have thrived


on raw cow's milk and sometimes buffalo milk. However, the latter is
not widespread in other parts of the world, just India.

Like whole eggs and other food sources of saturated fats, raw milk
has been considered dangerous.

Which I believe is not valid.

I have linked up two in-depth articles from authoritative sources that


will help you provide solid facts on why you should not fear raw milk.
These experts have explained it quite nicely. 298, 299

213
Cow’s milk is nutrient-dense.

It contains essential minerals like:


-Magnesium
-Potassium
-Calcium

It also has high-quality protein that helps in building muscle.

You can make products like yogurt, buttermilk, and paneer (cottage
cheese) through milk.

Yogurt and buttermilk have high probiotic content. Probiotics can be


beneficial for colon cancer, IBS and other intestinal infections. 300

Raw cow's milk contains fat-soluble vitamins A, D and K2. These


vitamins support brain health and nervous system development.

Raw milk is also packed with CLA (Conjugated Linoleic Acid) and
butyric acid (also found in ghee/coconut oil).

Again don’t just take my word for it, do your research. People drinking
raw milk are thriving, don’t let conventional wisdom misguide you.

Raw cow’s milk is a very healthy and versatile product that can be
incorporated into our daily diet as the main ingredient for smoothies
& shakes or used to make yogurt, butter, curd, ghee, cream, cheese,
etc.

214
Buttermilk

Buttermilk or lassi is a very well-known cooling summer drink in


India.

While some consider it the same, there is a slight difference between


buttermilk and lassi!

While both are high in probiotics, lassi is made by blending yogurt


with a bit of water and, optionally, some spices with salt or sugar or
actual fruits like strawberries and mangoes.

Buttermilk, also known as chhaas, is made by churning white butter,


is watery and has fewer calories than lassi.

Both of these can easily be prepared at home.

Buttermilk is a good source of high-quality protein, vitamin B12,


riboflavin, calcium, and phosphorus.

It helps people who are suffering from irritable bowel syndrome. 301

Just ensure it is made home from raw milk because pasteurization


destroys beneficial bacteria!

You can find a lot of YouTube videos on how to make your own
buttermilk or yogurt (the next probiotic food) at home.

Please note that you can still have this drink even if you are lactose
intolerant.

215
I have two lactose intolerant family members, my dad and my sister,
but they do well with yogurt and lassi as lactose (the sugar in milk) is
fermented by the bacteria.

How to include buttermilk (or lassi) in your diet:

You can have buttermilk either with your Indian meal or as a


standalone snack, with or without spices. It is also mixed with
chickpea flour and cooked into a curry with some herbs and
vegetables in some places.

In the next lecture, let's discuss yogurt and paneer (cottage cheese).

216
M6: Superfoods
L14: Superfoods: Proteins: Grass-fed Dairy:
Yogurt, Paneer

A nother powerful probiotic food is yogurt.

The same logic applies here.

It should be made from fresh raw milk because most


commercially available yogurts are loaded with added sugar and
made from pasteurized milk, which, as mentioned, destroys the good
bacteria.

A study conducted in 2016 in the United Kingdom confirms the


inclusion of more than 10g sugar in almost every 100g of commercial
yogurt that wasn't high fat or greek. 302

A few yogurt studies showed promising health benefits for certain


gastrointestinal conditions, including lactose intolerance,
constipation, diarrheal diseases, colon cancer, and inflammatory
bowel disease. 303

Some prominent bacteria cultures that ferment milk to form yogurt


are streptococcus thermophilus and lactobacillus bulgaricus.

217
Just like buttermilk, yogurt is loaded with protein (good for muscle
growth), calcium (excellent for bone health), magnesium, and vitamin
B12.

We can incorporate yogurt into our daily diet as a side dish, as an


addition to sauces, dips, smoothies or even as a standalone snack.

Cottage Cheese (Paneer)

Cottage Cheese (or Paneer) is formed when casein, a milk protein,


reacts to acids like lime or vinegar and coagulates.

It is a good source of protein and is often consumed majorly by


vegetarian bodybuilders and fitness enthusiasts.

100 g of cottage cheese has around 18 g of protein in it.

It is also a good source of calcium, which is required to strengthen our


teeth and bones and ensure proper nerve functioning and healthy
heart muscles.

It is rich in B-complex vitamins, which are necessary for many vital


functions of our body.

The potassium in cottage cheese helps maintain the fluid balance in


our body. Since potassium neutralizes the effect of high sodium in our
body, it lowers blood pressure and the contraction of blood vessels,
thus reducing the risk of cardiovascular diseases. 304

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It can be easily purchased in shops, but it's best to make it at home
from raw cow's milk as most store-bought cottage cheese is made
from pasteurized milk, with unwanted additives.

One can consume cottage cheese or paneer in a curry, a wrap, a


sandwich, grilled as a main dish or completely uncooked with a pinch
of seasoning.

Let's discuss meat and seafood in the next lecture.

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M6: Superfoods
L15: Superfoods: Proteins: Grass-fed Meat &
Wild-caught Seafood

G rass-fed meats are the most nutrient-dense proteins, with a

notable micro and macro-nutrient profile.

Unfortunately, 99% of US meat, dairy, and eggs come from factory


farms or CAFOs —Confined Feeding Animal Operations. The
situation is the same for fish. 305

Animals from CAFOs live in poor conditions. To increase survival


rates, they are pumped with antibiotics. They are also fed hormones
to increase their growth.

After all, meat is sold by weight. Therefore, the faster an animal


grows and the heavier the meat, the bigger the profits for the
companies that sell them!

However, grass-fed poultry is kept in a cleaner environment and is


organic. A lot of people steer away from grass-fed meats due to its
high price tag, but that shift is definitely worth it.

220
Products from pasture-raised animals are nutritionally superior to
products from grain-fed factory animals. They are lower in fat and
calories.

Pasture-raised products are high in omega-3s and vitamin E and are


free from antibiotics, hormones, and other diseases like e-coli. 306

Meat from grass-fed animals requires only one calorie of fossil fuel
energy to produce two calories of food instead of grain-fed animals
(in CAFOs) that require 35 calories of fossil fuel.

In conclusion, pasture-raised farming does not harm the environment


and is an excellent example of sustainable agriculture.

If you want to find out more about how we can feed 10 billion people
by 2050 without destroying the planet, check out the link to a video
in the Resource Manual. 307

We can eat grass-fed meats grilled, pan-cooked, cooked in a stew or


curry, sandwiches, pasta and many more dishes.

The bottom line is, if you are a regular meat-eater and consume eggs
and drink milk, I strongly urge you to be conscious of where your
animal-based protein is sourced from, not only for the sake of the
environment but also for better health for yourself and your family.

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Wild-Water Caught Seafood

Wild-water caught seafood refers to all fish and related food items
caught in their natural habitats like the lakes, rivers, sea and oceans.

The interesting water-based fauna is a staple food in almost all the


coastal areas in the world, yet underrated in most others.

However, with time, demand increased, and so did the trade of


farming fish. Fish are bred in artificially created environments and are
given an altered diet that boosts their growth to be sold quickly.

This process robs the fish of their health benefits to some extent and
instead adds the risk of contamination, disease and inclusion of heavy
metals, which we humans consume. 308

In comparison, the fish caught in their natural habitats get their


natural diet, like plants, algae or other fish or insects, depending on
the type. They also live to be more robust by surviving in the wild,
where other predators hunt them.

In addition, there is a far lesser risk of disease and contamination. The


most significant benefit is that they are not fed an artificially altered
growth-inducing diet. That is harmful to us.

Here are some benefits of wild-caught fish:

1. They are generally high in quality protein in comparison to


farmed fish.

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2. They are comparatively high in Omega-3 fatty acids, which are
super important for our health. 309
3. Studies have claimed wild-caught fish improved cardiovascular
health in humans. 310
4. Farm-raised fish are loaded with antibacterials, exposing us to
medicine-resistant pathogens and bacteria. Wild-caught fish
are not exposed to that. 311

If nature offers us a clean source of food, it's best not to try to


replicate it in labs and consume it as is.

Let's continue our discussion of superfoods by discussing the most


nutrient-dense foods high in healthy fats.

Thanks for listening.

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M6: Superfoods
L16: Superfoods: Fats: Healthy Oils

W hen it comes to discussing the inclusion of superfoods

rich in healthy fats, I'll divide it into three sections:

-Healthy Oils

-Nuts

-Seeds

I'll include the top 3 sources of superfoods in each of the categories


above.

Let's discuss top oils that you can include in your diet.

Ghee

Ghee has been a staple of Indian households for centuries.

Ghee has all the fat-soluble vitamins A, D, E & K. It also has CLA,
which has immense health benefits.

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Ghee has butyric acid, a short-chain saturated fatty acid that boosts
immunity and reduces chronic inflammation.

In the past few decades, ghee's popularity has suffered because


approximately 70% of ghee's calories come from saturated fats.

Recall from the myths and mistakes module; I debunk one of the
most prevailing myths about saturated fats.

The smoke point of ghee is 485 degrees Fahrenheit or 250 degrees


Celsius.

The smoke point is the temperature at which a given oil stops


shimmering and starts smoking continuously.

As you start to go above and beyond the smoke point, the oil breaks
down and releases harmful chemicals.

It's important to note that it's not just the smoke point that
determines whether the oil will turn rancid or not, but the oxidative
stability is what matters the most.

The oxidative stability of the oil is dependent on its chemical


composition.

Ghee has a higher concentration of saturated fats in them. And


saturated fats are very stable and do not oxidize when subjected to
heat or exposed to light or oxygen. 312

225
This is because saturated fats have single bonds between carbon
atoms. All other bonds are also saturated with hydrogen atoms.
These chemical properties make them very stable.

As a rule of thumb, any oil that has a higher concentration of


saturated fats in them will be way more stable when subjected to
heat, light, air or oxygen.

Pro-tip: When buying any oil, always choose the unrefined


'extra-virgin' variety, and ensure the oil has been 'cold-pressed.'

2) Extra-Virgin Cold-Pressed Coconut Oil

Moving on, I would place extra-virgin cold-pressed coconut oil next


on the list.

I'll be honest! The first time I tried coconut oil, it tasted a bit funny. It
has a unique flavor not many would find appealing.

But, I continued using it as my primary cooking oil and eventually


grew fond of it:)

Coconut oil is approximately 85% saturated fats, which scares most


people away.

It's important to note that lauric acid makes up 47% of the saturated
fat in coconut oil.

Lauric acid is medium-chain triglycerides directly metabolized by the


liver and used for energy.

226
Any excess MCTs are converted into ketones, which research has
proven beneficial for the brain.

MCTs are not stored as fatty tissue in the body but instead used for
energy.

Cold-pressed coconut oil's smoke point is at 350 degrees Fahrenheit


(177 degrees Celsius), which is enough to make it stable for all types
of cooking methods.

You see, when you saute it in a pan, the average temperature is


around 120 degrees Celsius. Deep frying is about 170 degrees
Celsius, and roasting is around 180 degrees Celsius.

Also, 85% of coconut oil is saturated fats, so rest assured they are
stable enough for any cooking style.

Therefore a big thumbs up to coconut oil as a healthy fat that can be


used for cooking.

Extra-virgin Olive Oil

Everyone loves extra-virgin olive oil. This is because 73% of olive oil
is made of monounsaturated fats.

The remaining percentage is omega-6 polyunsaturated fats. Olive oil


consists of 14% saturated fatty acids.

Olive oil is anti-inflammatory and can also act as an antioxidant.

227
The smoke point of extra-virgin olive oil is less than ghee and is
somewhere close to 190 degrees Celsius ( 375 degrees Fahrenheit),
which is enough to make them stable for all kinds of cooking.

A large study involving 841,211 subjects concluded an overall 12%


reduced risk of cardiovascular mortality and 17% reduced risk of
stroke in subjects who consumed olive oil. 313

In 2015, a systematic review and meta-analysis by Lukas


Schwingshacki et al. suggested a Mediterranean diet, where a key
ingredient is olive oil, has beneficial effects on inflammation and
endothelial function markers. 314

Yet another study suggested olive oil had a small beneficial effect on
systolic blood pressure. 315

It is important to note that not all olive oil brands are of good quality.

Types of olive oil on the market include lampante, extra virgin, virgin,
pomace, refined, organic, and stone-milled.

Deciding which olive oil to buy can get confusing with so many
varieties.

I have linked up an in-depth article in the resource manual that will


help you decide the best extra-virgin olive oil (the healthiest to
consume) to buy.

Let's discuss the different types of nuts in the next lecture.

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M6: Superfoods
L17: Superfoods: Fats: Nuts

S tudents, there are many exotic superfoods that I have

deliberately not included in my list.

My reason is clear: Being healthy does not have to be expensive.

To get the nutrients your bodies need, you don't have to buy exotic
superfoods like spirulina, cholera, macadamia, brazil nuts, etc.

Just focus on buying local, seasonal, and fresh superfoods and ensure
enough variety.

If you can afford macadamia and brazil nuts, then, by all means,
include them in your diet as they are nutrient-dense.

However, the nuts I will discuss can easily be categorized as


superfoods and healthy when eaten frequently.

Let's start with walnuts.

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Walnuts

Walnuts provide traces of manganese, magnesium, copper,


phosphorus, vitamin B6, and vitamin E.

They are high in monounsaturated and polyunsaturated fats and


omega-3 fatty acids.2

Antioxidants are more abundant in walnuts than in any other nut due
to vitamin E, melatonin, and polyphenols found in their papery skin. 3

The above compounds help to decrease LDL (bad) cholesterol and


triglycerides. 316

Polyphenols can help fight oxidative stress and inflammation in our


bodies. 317

Research suggests that walnuts can also reduce the risk of prostate,
colon, colorectal, and breast cancers.318, 319

Walnuts are a good source of omega-3s. One ounce (28g) or 14


walnut halves provides ~2.5g of ALA (alpha-linolenic acid).

Regular consumption of walnuts may also reduce the risk of type-2


diabetes.

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Almonds

Any time I feel hungry or crave something, almonds come to my


rescue!

They act as perfect snacks that not only keep my caloric intake in
check, but they're also loaded with nutrients.

Almonds are a rich source of antioxidants. They provide vitamin E,


which contains the antioxidant tocopherol, protecting our cells from
oxidative damage or oxidative stress dealt by free radicals. 320

In addition, almonds contain almost all B vitamins except vitamins B7


& B12, along with choline, folate, vitamin A, calcium, iron,
magnesium, phosphorus, potassium, selenium, zinc and manganese.

A 28g serving of almonds can provide us with 6g of protein and 3.5g


of fiber.

Almonds help boost bone, skin and heart health.

Studies have shown that almond consumption significantly improves


lipid profiles, insulin sensitivity, and uric acid levels. 321

Almonds can be eaten as it is, or they can be processed into almond


milk, almond butter or almond flour.

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Peanuts

Peanuts or groundnuts are widely cultivated worldwide, with India


being one of the largest producers of peanuts.

Peanuts are used in different cuisines as a roasted delicacy, like butter


or even made into a sauce.

Health enthusiasts take a special interest in peanuts, with peanut


butter, in particular, being a favorite of many.

The primary reason behind this is the high protein content. For
example, 100g peanut butter provides 22-24g of proteins or 3.9g
protein for every tablespoon(16g); however, the protein content can
vary based on different brands. 322, 323

Peanuts are also a significant source of healthy fats, with 50% of


calories coming from monounsaturated.

This macronutrient protein makes peanuts a good idea for keto


warriors.

Lastly, they also contain fiber and a good amount of B vitamins,


calcium, copper, sodium, potassium, polyphenols, flavonoids, and
phenolic acids.

Overall, peanuts are a nutrient-dense food and a great addition to


one's diet.

How to include nuts in your diet:

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Add chopped nuts to salads, oatmeal, and yogurt.

Chopped nuts and nut flour are healthy alternatives to other kinds of
flour in cakes and bread.

Furthermore, you can grind them and add them to smoothies, dips,
and even sauces.

Just be mindful of their portions, as nuts are high in calories.

A few hundred calories of mixed nuts can easily be part of a balanced


diet. Just ensure that it fits your macros and total calorie targets
based on your fitness goals.

Let's discuss seeds in the next lecture.

233
M6: Superfoods
L16: Superfoods: Fats: Healthy Oils

C hia seeds

Also known as Salvia Hispanica, chia seeds have gained a reputation


to be very healthy.

They are a great source of healthy omega-3 fatty acids and


carbohydrates and rich in protein, fiber, and micronutrients.

Research has shown that chia seeds are rich in antioxidants due to
phenolic compounds like myricetin and quercetin. 324

Antioxidants protect our bodies against numerous degenerative and


chronic diseases by balancing out oxidative stress. 325

One ounce of chia seeds provides 9.75 g of fiber, a pretty impressive


number.

The fiber in chia seeds is mainly soluble fiber and mucilage, which
gives moistened chia seeds a gluey texture. Fiber also assists us with
fat loss and relieves symptoms of constipation.

They are high in calcium, phosphorus, and magnesium, essential for


bone health.

234
They help type-2 diabetes patients. A study was conducted on 20
diabetes patients, and it was found that consumption of 37g of Chia
Seeds every day helped reduce their blood pressure, inflammation
and cardiovascular disease risk. 326

I personally like adding chia seeds to my smoothies, yogurt and oats


as a topping, but it is also advised to soak chia seeds overnight in
water and drink it in the morning as a ritual for good benefits!

Flaxseeds
Flaxseeds are among the oldest crops cultivated in human history.

They are not only a superb source of omega-3 fatty acids but are also
very high in fiber with a decent amount of protein.

In addition, they contain lignans, which are antioxidants that protect


our bodies against free radical damage.

A 50g serving of flaxseeds provides around 11-12g of omega-3 fatty


acids, approximately 13-14g of fiber(that even exceeds the fiber
content in some dals by weight) and 9-10g of protein. 327

Regular flaxseed consumption may be helpful in the two most


common chronic conditions today, type-2 diabetes and cardiovascular
diseases.

A study published in 2011 quoted, "Supplementation with flaxseeds


reduced fasting blood glucose by 19.7% and glycated hemoglobin by
15.6%.

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A favorable reduction in total cholesterol (14.3%), triglycerides
(17.5%), low-density lipoprotein cholesterol (21.8%), and
apolipoprotein B and an increase in high-density lipoprotein
cholesterol (11.9%) were also noticed." 328

Flaxseed oil, in addition, is one of the best options for vegans and
vegetarians to get their quota of omega-3 fatty acids considering that
they do not consume it from animal-based food sources.

Hemp Seeds
Hemp or industrial hemp is a variety of the Cannabis Sativa plant. It is
one of the fastest-growing plants.

Hemp is often confused with marijuana as both are from the same
species.

However, hemp contains only a small amount of THC


(tetrahydrocannabinol), the psychoactive compound in marijuana but
high in CBD (cannabidiol), reducing or eliminating its psychoactive
effects.

Hemp seeds are the seeds of the hemp plant. They have a pleasant
nutty flavor and crunchy texture.

They are a mine of minerals like iron, copper, manganese, phosphorus


and magnesium.

They also contain a significant amount of omega-6 and omega-3


fatty acids in the optimum ratio of 3:1. 329

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Hemp is a high-quality vegan protein, holding all nine essential
amino acids.

Hemp seeds have a significant amount of amino acids arginine,


methionine, and cysteine. However, the lysine content in hemp seeds
is limited. 330

The protein content in hemp seeds has made it a popular source of


protein supplementation in the vegan category.

One can include healthy varieties of seeds in their meals on top of


salads, ground or soaked, depending on what kind of seed one is
consuming or, at times, as a standalone snack.

237
M6: Superfoods
L19: Superfoods: Beverages: Green Tea

L et me start by saying that water should be the first beverage

you should reach out for to quench your thirst and hydrate your body.

It is the healthiest drink out there, and drinking 6-8 glasses daily is a
must for optimal health.

However, if you need taste and more nutrients in your diet, you can
include the following 7 healthy beverages.

Let's start by discussing the most common beverage: Green Tea.

Green Tea

Tea is from the plant Camellia Sinensis, consumed in all parts of the
world.

The three significant forms of tea are green, black, and oolong tea
based on the degree of fermentation.

The tea composition differs from species, season, leaves, climate, and
horticultural practices.

238
However, among these, the most significant effects on human health
have been observed with the consumption of green tea. Let's look at
the green tea nutrition facts.

Green Tea Nutrition

Infused green tea is primarily water-based, fat-free, with no


carbohydrates, and since it's not sweetened, there aren't any calories
either.

However, it does contain minerals and traces of elements such as


magnesium, potassium, chromium, manganese, zinc, molybdenum,
selenium, sodium, phosphorus, cobalt, fluorine, and aluminum. 331

Several polyphenolic compounds, including flavonols, flavonoids, and


phenolic acids, are found in green tea and may constitute more than
30% of the dry weight.

It gets its nutritional status from plant compounds called catechins,


specifically epicatechin, epicatechin-3-gallate, epigallocatechin, and
EGCG.

These are believed to be responsible for giving green tea its potential
cancer-fighting, antioxidant and metabolism-boosting benefits. 332

239
Green Tea Health Benefits

Heart Health

Much scientific research suggests that green tea may have various
health benefits, which have been attributed to the presence of
polyphenols contained in tea leaves. However, the polyphenols in tea
leaves depend on the leaves' preparation.

Green tea may lower blood pressure too and thus lessen the risk of
stroke and coronary heart disease. 333

Cancer Health

Green tea has also been associated with preventing certain types of
cancer, including mammary glands, lungs, colon, esophagus, mouth,
stomach, small intestine, kidney, and pancreas. 334, 335

Studies suggest that tea polyphenols lower cancer cell duplication


rates, hamper cancer growth, increase apoptosis, and lower
angiogenesis. (the development of new blood vessels that tumors
need to grow.)

Tea polyphenols alter the intestinal bacterial flora, suppressing


undesirable bacteria and favoring the growth of beneficial bacteria.336,
337, 338

Green tea polyphenols are now considered medicinal agents in


systematic studies, focusing on altering brain aging processes and

240
serving as a possible agent in progressive neurodegenerative
disorders such as Parkinson's and Alzheimer's diseases. 339

The effects of tea on diabetes and obesity have gained increasing


attention as tea catechins, especially EGCG, appear to have
anti-obesity and antidiabetic effects. In addition, recent human
studies indicate that the consumption of green tea and green tea
extracts may help reduce body weight, mainly body fat, by increasing
energy expenditure and fat oxidation.340

Green tea variety has also been shown to be anti-inflammatory,


which helps keep the skin clear and glowing.341, 342

I hope all this information on green tea health benefits will encourage
our readers to switch from other beverages to green tea.

But don't we all get flustered by the options available in a store.

While there are several green tea sachets and loose-leaf options to
choose from, we have to be mindful of ingredient quality, sourcing,
sustainability, and, of course, flavor.

You can check out the link to an article on Green tea on our blog to
find out how to select the finest quality of green teas available in the
market.

Let's continue in the next lecture.

241
M6: Superfoods
L20: Superfoods: Beverages: Apple Cider Vinegar

T he first time I tried it, honest to God, I didn't like the taste.

But then, after reading about its amazing health benefits, I thought I
would give myself a month, and if I still don't like it, I will stop using
it.

It didn't take me long enough to start cherishing this fabulous liquid


which some say is more than 2000 years old.

The father of modern medicine, Hippocrates, gave this liquid to his


patients to help them heal their bodies.

This liquid is Apple Cider Vinegar.

There are many brands of Apple cider vinegar out there, but what
you should look for is raw, organic, unfiltered and unpasteurized.

Benefits of Raw, Unfiltered Apple Cider Vinegar

The top benefit of apple cider vinegar is that it helps stabilize your
blood sugar. 343

242
For example, let's say you have 2 slices of white bread. Now white
bread is pretty high on the glycemic index and will raise your blood
sugar quickly.

But if you have apple cider vinegar along with it, you can lower your
blood sugar by 34%!

A study in the European Journal of Clinical Nutrition proves this fact.


344

A few other studies support this fact by confirming that apple cider
vinegar helps by lowering your blood glucose and improves insulin
sensitivity. 345

This is good news for people who have type 2 diabetes or anyone
who is prediabetic.

I have always stressed that managing your insulin levels is a


significant step towards lowering your weight.

Besides weight loss, ACV also helps lower your cholesterol levels
and reduces the risk of heart disease. 346, 347, 348

This is because of a compound called acetic acid.

Acetic acid- the main compound of apple cider vinegar is made by


adding yeast, which acts on naturally occurring sugar in organic
apples by fermenting it.

243
How to include apple cider vinegar in your diet.

Start by adding 5ml of apple cider vinegar to 100 ml of water. Then,


slowly sip it for 30-60 minutes. After that, you can gradually increase
the quantity to 15ml added in 250ml of water.

If you want to consume more, you can add another tablespoon to


your salads, especially when having a high-carb meal.

Lastly, never drink it straight up; obviously, you would hate the taste,
but it may burn your food pipe, so always dilute it with water or pour
it over your salad.

244
M6: Superfoods
L21: Superfoods: Beverages: Matcha Tea

M atcha is a powdered Japanese green tea (Camellia Sinensis)

of the Tencha variety.

It's my personal favorite. Here are many reasons why.

For the longest time, I was looking to complement my coffee intake


with another beverage that could help me sustain my long periods of
fasting and therefore provide me with focus and alertness.

My weeks of research ended with a beverage called Matcha Tea.

Matcha's caffeine content is high compared to other green teas. For


every 8 ounces of matcha tea, you get ~70mg of caffeine. This is
about three times higher than any green tea.

However, the effects of caffeine are altered by an amino acid called


l-theanine.

Matcha is rich in an amino acid called l-theanine and contains about 5


times more l-theanine than any green tea.

245
This amino acid creates alpha brain wave patterns and promotes
relaxed alertness.

For thousands of years, matcha tea was popular amongst monks who
used to drink it to aid their meditation practice.

Along with caffeine, it provides 137 times the antioxidant content


compared to low-grade green tea and three times the antioxidants
compared with high-quality green tea. 349

Matcha is one of the abundant sources of flavonoids, especially rutin.


Rutin is a plant compound with an antioxidant effect and belongs to
polyphenols. It has anti-inflammatory properties and supports the
immune system. 350, 351

It may help in preventing diseases like cancer, heart disease and


diabetes. 352, 353, 354, 355

Matcha may help lower blood glucose levels and blood pressure. 356,
357

Furthermore, it could also prevent liver damage and decrease the risk
of liver disease. Although studies are limited and more research is
needed to establish this claim. 358, 359

It's effortless to make matcha tea. Just boil some water, and add 2-3
grams of matcha tea powder. Whisk it for about 30 seconds, and you
are good to go.

You can add it to smoothies or sprinkle it over a bowl of oats or


salads.

246
M6: Superfoods
L22: Superfoods: Beverages: Moringa Tea

M oringa tea is acquired from the leaves of the Moringa

oleifera tree. The moringa tree is native to India and has several
common names, including "the miracle tree," 'drumstick tree' or
'horseradish tree.

Moringa tea offers an earthy flavor comparable to that of green tea.


However, it is less bitter and sharp than most varieties of green tea
and can tolerate high temperatures and extended brewing times. The
tea is usually flavored with honey, mint, and cinnamon to balance the
earthy notes.

Moringa tea acquires its nutrients from the dried moringa leaves and
is abundant in potassium, calcium, phosphorus, iron, and vitamins A,
C, and D.

The tea may also have high essential amino acids, antioxidants such
as beta-carotene, polyphenols, and flavonoids like kaempferol and
quercetin. Moringa tea does not contain caffeine. 360

Moringa tea is primarily known as an anti-inflammatory tea. The


polyphenols, tannins, saponins, and others in the leaves help combat

247
chronic inflammation throughout the body, relieving pain, aches,
stomach upsets, headaches, and fever. 361, 363

Moringa tea may help people with diabetes regulate their blood
glucose levels. Many animal studies and some human studies
suggest that moringa tea consumption can lower glucose levels post
meals.

Researchers suggest that differences between moringa varieties and


preparation methods could cause differing results. 364, 365

The powerful antioxidants in moringa tea may also help improve hair
and skin quality by beating inflammation and oxidative stress in the
body. 366

So this was all about moringa; thanks for listening.

248
M6: Superfoods
L23: Superfoods: Beverages: Coconut Water

C oconut water is the clear fluid inside the coconuts of a coconut

palm tree. Coconut water has a sweet, refreshing taste for those
unacquainted with the drink. Young green coconuts are tastier and
plentiful in volume.

Coconut water has a therapeutic effect, with various nutrients such as


minerals, vitamins, antioxidants, amino acids and enzymes. 367

Lauric acid, a fat present in coconut water, has antibacterial,


antibacterial and antiviral properties, supporting the body's immune
system.

It improves digestion and absorption of many nutrients. Potassium


and magnesium benefit blood pressure and heart functions.368

Coconut water may also assist in the fight against acne due to its
antimicrobial properties. Research also suggests that consuming
coconut water may help the antioxidant system by neutralizing the
effects of free radicals. 369

Coconut water is mother nature's sports drink and can be a part of an


active lifestyle as it helps to hydrate the body.

249
Try and consume coconut water directly from coconuts.

Suppose you live in a city where you cannot access fresh coconut
water. In that case, some companies offer 100% coconut water
without the added preservatives; therefore, opt for these as the next
best alternatives.

You can drink coconut water as a standalone snack any time of the
day.

250
M6: Superfoods
L24: Superfoods: Beverages: Kombucha

K ombucha is a fermented beverage, much like cultured yogurt,

cheese, kefir, kimchi and sauerkraut and made by fermenting tea,


generally black tea or sometimes green and oolong tea and sugar,
with a symbiotic culture of bacteria and yeast (SCOBY), generally for
7–10 days.

It is then bottled for 1-2 weeks to contain released CO2 and


encourage carbonation. From there, bottled kombucha is placed in a
refrigerated environment to slow down the carbonation and
fermentation processes.

The SCOBY comprises various acetic acid bacteria and yeasts. After
fermentation, kombucha is a cocktail of chemical components
including sugars, tea polyphenols, organic food acid, fiber, ethanol,
amino acids including lysine and essential nutrients such as copper,
manganese, and zinc, water-soluble vitamin C, and many B vitamins,
antibiotic substances and enzymes.

The quality and quantity of the chemical components may vary,


mainly depending on the microorganisms of the symbiotic culture
used for the fermentation of kombucha, fermentation time and
temperature, sugar content, and type of tea used. 370

251
One of the main benefits of adding kombucha to the diet is that, like
other fermented foods, it is rich in probiotics.

And probiotic bacteria are similar to the friendly bacteria present in


the gut, and they help with diarrhea and irritable bowel syndrome
(IBS). They may even strengthen the immune system. 371

If the kombucha is made from green tea, the health benefits may
increase, including bioactive compounds, such as polyphenols, that
act as antioxidants and protect our cells from damage.

We need more human cohort studies to understand its role in cancer


and heart diseases.

Still, kombucha consumers are increasing worldwide, the brew being


a delicious combination of a delicate sour taste, antioxidant
properties of tea extracts, and the potentially beneficial effect of
fermenting bacteria.

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M6: Superfoods
L25: Superfoods: Beverages: Lemon Juice

L emons are a very healthy fruit with a distinct taste and smell,

making them a great addition to foods and drinks.

However, they are rarely consumed on their own due to their intense
sour flavor. Interestingly, while lemons are naturally acidic, they
become alkaline after digesting them.

Lemon contains many vitamins like niacin, thiamine, choline, folate,


vitamin C, vitamin B6, and minerals, including calcium, copper, iron,
manganese, magnesium, phosphorus, potassium, zinc, which all are
essential for the human body. 372

We get lemon juice (Citrus Limon) from lemons with many uses, from
culinary to medicinal.

The juice contains many bioactive compounds such as flavonoids,


carotenoids, limonoids, tannins, and terpenoids. These plant
compounds have antibacterial and antifungal properties. 373

The antibacterial compounds in lemons can cure mouth infections like


gingivitis and act as a laxative in the digestive system.

253
Lemon juice has been used medicinally for hundreds of years. For
example, people have used lemon juice for virus prevention and have
mixed it with honey and ginger as an effective cold treatment.

Lemons contain hesperidin, known to reduce hypertension symptoms


in people prone to high blood pressure. 374

Additionally, lemons contain pectin and limonoid compounds, both of


which may slow atherosclerosis, a condition where the arteries start
hardening.

One 2014 study suggested that women in Japan who walked


regularly and consumed lemon daily had lower blood pressure than
those who did not. 375

In addition, compounds in lemons may reduce Low-density


lipoprotein levels (LDL), referred to as bad cholesterol, in the blood.
376

Lemons play an active role in flushing out bacteria that can cause
urinary tract infections (UTIs). In addition, they have antibacterial,
antifungal, antidiabetic, anticancer, and antiviral properties due to
alkaloids. 377

The main content of lemon juice is vitamin C and citric acid. The
content of vitamin C and citric acid makes the degree of acidity (pH)
of the lemon juice become acidic. 378

Research has proved that foods rich in vitamin C may help prevent
free radical damage that may lead to cancer. 379

254
Vitamin C is also vital for immune system functioning, wound healing,
and helping the body absorb iron from foods.

A 2014 study suggested that eating foods rich in vitamin C can help
prevent skin damage from sun exposure, infections, pollution, and
aging. 380

Vitamin C in lemon juice is also great for boosting immunity and


fighting cold and flu. In addition, it may reduce symptoms and
shorten the duration of respiratory tract infections. 381

Eriocitrin, the primary lemon polyphenol (LPP), is a yellow and


water-soluble antioxidant abundant in lemon juice and peel.

Drinking lukewarm water with lemon early in the morning on an


empty stomach is a naturally detoxifying drink. Apart from hydration,
lemons can fight water retention in the body. Lemon juice water may
reduce constipation, promote digestion and prevent obesity.

Add lemon juice to drinks, salads, meats or pickle them. There are
great ways to incorporate lemon juice into the daily dose.
As they say, "When life gives you a lemon, say thank you."

And a big thank you for listening to all the lectures so far.

We are left with the condiment section in the module superfoods.


Let's continue in the next lecture.

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M6: Superfoods
L26: Superfoods: Condiments: Turmeric

W e have come to the last category of superfoods: Healthy

Condiments.

Let's first focus on the healthy spices used in Indian cuisine.

Let's start by discussing a spice known worldwide to have fantastic


health benefits- Turmeric.

Turmeric is an herb from the ginger spice family and is widely used
throughout India to enhance the color and flavors of foods and
traditional medicine.

Historically, turmeric has been part of Ayurveda and other traditional


Indian medical systems due to its active ingredient, curcumin.

Curcumin is acquired from the herb's stems and is widely known for
its antioxidant and anti-inflammatory effects.

Today, turmeric is encouraged as a dietary supplement for various


conditions, including arthritis, digestive disorders, respiratory
infections, allergies, liver disease, depression, etc.

256
For better absorption, one should consume it with a source of fat
(such as avocado, nut butter, nuts, fish, etc.). Therefore curcumin will
directly be absorbed into the bloodstream and bypass the liver.

Turmeric is a common spice and a primary ingredient in curry powder.


Curcumin is a major component of turmeric, and the activities of
turmeric are commonly attributed to curcuminoids (curcumin and
closely related substances).

The curcumin in turmeric has proven solid anti-inflammatory


properties that block the action of inflammatory molecules in the
body. Studies suggest the positive effects of curcumin on people with
arthritis and inflammatory bowel disease. 382, 383

Curcumin is a robust scavenger of oxygen free radicals, which are


chemically active molecules that cause damage to the body's cells.

Curcumin is a potent antioxidant and can play an active part in


preventing and managing heart disease. Turmeric has also been
shown to lower triglycerides and cholesterol in people at risk of heart
disease and improve blood pressure. 384, 385

Various human and animal studies have explored turmeric's influence


on cancer. Many have found that it can reduce the spread of cancer,
contribute to the death of cancerous cells in various cancers, and
reduce the adverse side effects of chemotherapy. 386, 387

Antioxidants in turmeric may improve eye health by reducing the risk


of cataracts, glaucoma, and macular degeneration. 388, 389

257
Given its anti-inflammatory and antioxidant properties, studies
suggest curcumin might effectively treat symptoms of anxiety and
depression in people suffering from major depressive disorder (MDD)
and the medicines. 390, 391

Curcumin protects the skin by resisting free radicals and minimizing


inflammation. Evidence suggests that curcumin may help the skin
conditions like psoriasis, scleroderma, acne and skin cancer. 392, 393

Turmeric can be an ingredient in soups, sauces, curries, meat dishes,


biscuits, rice preparations, and spice kick in smoothies and juices.

258
M6: Superfoods
L27: Superfoods: Condiments: Common Spices

C umin

Cumin is a spice from the dried seed of a plant known as Cuminum


cyminum, a parsley family member. It adds a smoky note and an
intense aroma to most Indian curries and vegetables.

Cumin seed is usually the first spice added while cooking Indian
dishes, fried in dry form and roasted before use. It's also dry roasted
and converted to powder before being added to recipes like raita and
buttermilk.

Ancient Ayurvedic applications of cumin in India included treatment


for gastrointestinal distress, diarrhea, and jaundice.

In contrast, today, it is used for hypertension, epilepsy, fever,


childhood maladies, and gynecological and respiratory disorders.

Using cumin as a spice increases antioxidant intake, promotes


digestion, provides iron, improves blood sugar control, and reduces
food-borne illnesses. 394, 395, 396, 397

259
Cardamom

The spice cardamom, also addressed as the "queen of spices," is


produced from the plant Elettaria cardamomum, found in the form of
a small pod with black seeds inside.

It's the third most expensive spice globally, mainly because it's
harvested by hand and requires a lot of manual work. While the
green cardamom has a light and mild eucalyptus tone, the black
cardamom is smoky, spicy and generally used only for its seeds.

Unique to Indian taste buds, cardamom is fantastic to our land and


senses and tastes to tea, foods like curries, bread, rice, etc.

In ancient traditional medicines, cardamom alleviated digestive


disorders and obesity, and even today, people consume it for ailments
such as bronchitis, dysentery, bad breath, and infections.

Studies have suggested that cardamom contains chemicals that


might treat intestinal spasms, kill some bacteria, reduce swelling, and
help manage diabetes and uplift the immune system. 398, 399, 400

260
Fenugreek

Fenugreek seeds, or methi, are native to the Mediterranean region,


southern Europe, and western Asia.

Fenugreek seeds have a tangy bitter taste that brings signature curry
smell and taste to Indian dishes, but one should use them sparingly.

Fenugreek is an ingredient in spice blends, a flavoring agent in foods


beverages, and used in traditional and alternative medicine.

Fenugreek seems to relax sugar absorption in the stomach and


stimulate insulin.

Both of these effects lower blood sugar in people with diabetes.


Fenugreek might also improve levels of testosterone and estrogen. It
is given to women to increase milk supply during breastfeeding and
relieves menstrual cramps. 401, 402, 403

Coriander

Coriander seeds are aromatic, tiny, round brown seeds of the


coriander plant (Coriandrum sativum L.) ground into a powder used in
gravies and curries.

The whole seeds can also be roasted, pounded, and included in meat
rubs and marinades.

It is full of fiber that improves digestion and is good to improve bowel


movement.

261
Coriander seeds, extract, and oils may help lower blood sugar and
promote insulin growth.

Coriander is full of antioxidants that assist in immune-boosting,


anticancer, anti-inflammatory, and neuroprotective effects in our
body. 404, 405

The seeds are used in the spice mix, meat, poultry and seafood curry
dishes, and various ethnic foods.

Garam masala

Garam masala is an Indian kitchen staple integral to many traditional


recipes. The most common spices featured in garam masala include
cloves, cinnamon, cumin, nutmeg, peppercorn, cardamom, and bay
leaves.

Although the north Indian version is most commonly used, garam


masala recipes vary by region, and many Indian families have their
unique blend.

Cloves, cumin, pepper, and cardamom in the garam masala keep


acidity and indigestion at bay.

Most of the ingredients are rich in phytonutrients, which help boost


metabolism, prevent skin problems, and help fight inflammation.

Cardamom and cloves in the garam masala also help dental and oral
health.

262
M6: Superfoods
L28: Superfoods: Condiments: Raw Honey

H oney is a natural product obtained from the nectar of flowers

by honeybees and has been a part of humans since ancient times,


nearly 8000 years ago.

Most ancient populations, including the Greeks, Chinese, Egyptians,


Romans, Mayans, and Babylonians, consumed honey for nutritional
and medicinal properties.

Honey is the only insect-derived natural product, and it has


nutritional, cosmetic, therapeutic, and industrial values.

Honey never spoils and does not need refrigeration.

Honey has a potential therapeutic role in treating disease by


phytochemical, anti-inflammatory, antimicrobial, and antioxidant
properties. Flavonoids and polyphenols, which function as
antioxidants, are two main bioactive compounds present in honey.

It is the main component of Ayurveda and naturopathy and is also


used to replace sugar by many fitness enthusiasts.

263
Honey is primarily composed of sugar, with small amounts of
vitamins and minerals like sodium, riboflavin, Vitamin C, iron, and is
rich in health-promoting plant compounds. 406

Honey controls the LDL (bad) cholesterol levels and boosts the good
cholesterol levels in our body. 407, 408

It contains antimicrobial and antioxidant properties that are useful for


gastric problems. It has a compound called methylglyoxal which
fights germs and harmful bacteria in your digestive tract. It also
protects our bodies from infections. 409, 410, 411

It controls nausea and prevents vomiting. Millions of people start


their morning by adding lemon juice to raw honey to a glass of
lukewarm water to relieve and start their mornings. 412

There are endless benefits of honey for our health and skin as well. It
is also a chief component of all age-old Indian home remedies. 413, 414

However, it's important to note that all the health benefits discussed
can be mainly attributed to raw honey.

Raw honey is unprocessed and never heated. It comes straight from


the beehive and retains the beneficial bacteria and nutrients.

Raw honey is a better alternative to white sugar. However, it still has


fructose and is high in calories. Therefore, it's good to practice
moderation, and 1-2 tablespoons daily may suffice.

264
M6: Superfoods
L29: Superfoods: Condiments: Cinnamon

C innamon is a spice derived from the branches of trees of the

Cinnamomum family. It is native to southeast Asia, the Caribbean,


and South America.

Cinnamon is a fragrant household spice that comes from the inner


bark of tropical trees of the Cinnamomum family.

When dried, it curls into quills that add a warm, distinctive flavor and
aroma to sweet dishes and savory dishes in Asian, Middle Eastern
and North African cuisines.

Cinnamon is also used in the aroma and essence industries due to its
fragrance, incorporated into different foodstuffs, perfumes, and
medicinal products.

The most critical components of cinnamon are cinnamaldehyde and


trans-cinnamaldehyde (Cin), which are present in the essential oil,
thus contributing to the fragrance and the various biological activities
observed with cinnamon. 415

265
Cinnamon is considered to have many medicinal and soothing
properties and is used frequently in Chinese and Indian herbal
medicine.

The distinctive smell and flavor of cinnamon derive from the essential
oils contained in the bark, called cinnamaldehyde. Cinnamaldehyde
displays antiviral, antibacterial and antifungal properties. 416, 417

Cinnamon has the approval for helping in managing blood sugar. It


appears to do this by several different mechanisms, including
controlling the amount of glucose that enters the bloodstream.
Human experiments are promising and suggest cinnamon may
moderate lower fasting blood sugar levels in those with diabetes. 418,
419

Cinnamon has also been used as tooth powder to treat toothaches,


dental problems, oral microbiota, and bad breath. 420

Cinnamon can also improve the colon's health, thereby reducing the
risk of colon cancer. 421

Some corroboration suggests that the consumption of cinnamon is


associated with a significant drop in systolic and diastolic blood
pressure. 422, 423

Cinnamon contains powerful antioxidants, such as polyphenols which


may protect the body from oxidative damage caused by free radicals.
424, 425

266
In addition to all the above, cinnamon has been used for flatulence,
gastrointestinal complaints and many other ailments.

Depending on the cultural, culinary context, cinnamon is added to


beverages, liqueurs, teas, chicken, and lamb dishes. And cinnamon
and sugar also go hand-in-hand, meaning they're perfect on toast,
baked goods, fruits and other desserts.

267
M6: Superfoods
L30: Superfoods: Condiments: Sauerkraut

T he superfood condiments list would be incomplete without

discussing the probiotic-rich foods such as sauerkraut and kimchi.

Let's start with sauerkraut.

Sauerkraut is a German word translated as acid (Sauer) cabbage


(kraut).

It is a traditional European dish made from fermented cabbage and is


believed to be a part of the European diet since the 4th century BC.
The fermentation process used in sauerkraut is one of the oldest and
most commonly used.

Sauerkraut was invented as a means of preserving cabbage.

It is made by mixing shredded fresh cabbage and salt and pressing it


down on the mixture.

The beneficial bacteria present on the surface of the cabbage and


from the air in the environment start to break down the natural
sugars in the cabbage into lactic acid.

268
Depending on your serving size, the fermentation could take anything
from three to five days to complete. You can, of course, leave it for
longer without worrying about it getting spoiled.

As a superfood, sauerkraut is ​loaded with nutrients and is low in


calories. It's an excellent source of vitamins and minerals, including
iron, calcium, selenium, manganese and folate.

In addition, with its high fiber content, it promotes digestive health


and keeps you regular. 426

The consumption of probiotic-rich foods, such as sauerkraut, kefir,


yogurt, miso, etc., has been associated with several health benefits,
like weight maintenance and a reduced risk of type 2 diabetes and
cardiovascular disease.

Many studies have supported a link between fermented foods and


improvement in the metabolic parameters of human bodies. 427

Studies show that fermented cabbage has antioxidant and


anti-inflammatory properties because of phytochemicals, vitamin C,
and iron, all of which contribute to a more robust immune system. 428

Sauerkraut may help with weight loss, as it is low in calories and high
in fiber and probiotic content that can help us feel full longer. This
combination makes sauerkraut an excellent food to aid weight loss
and unwanted body fat loss. 429, 430, 431

The most regular variety of cabbage used in traditional sauerkraut is


white or green. But red cabbage can be an excellent choice, too, for

269
an extra boost of antioxidants. It's easy to make your sauerkraut,
which stays for a while in your fridge.

The best way to include it in the diet is by adding a few spoonfuls to


your plate at a meal.

270
M6: Superfoods
L31: Superfoods: Condiments: Kimchi

K imchi is a traditional Korean recipe made with salted

fermented vegetables, which involves Korean cabbage and


seasonings like sugar, salt, onions, garlic, ginger, red chili powder,
seafood etc.

It may include other vegetables, including radish, celery, carrot,


cucumber, spinach, scallions, beets, and bamboo shoots.

There are many types of kimchi, more than 167, depending on the
main ingredient, region, and preparation methods.

Kimchi is made by cutting vegetables into strips or slices, rubbing


them with salt to create a brine, along with the spices, and then
densely packing the mixture into a jar and letting it ferment for a few
days, but often longer, at room temperature.

It can be consumed fresh or unfermented immediately after


preparation. Kimchi is tasty and highly functional; it is generally
served with steamed rice at every Korean meal.

Several bacteria are involved in kimchi fermentation, but probiotic


lactic acid bacteria are the dominant species in the fermentation

271
process. These friendly bacteria can benefit your digestive health and
gut wellness. 432, 433

Kimchi (baechu or cabbage kimchi) is a low-calorie food. It contains


high vitamins like vitamin C, A, vitamin B complex and minerals like
sodium, calcium, potassium, iron, and phosphorus. 434

It is a rich source of dietary fiber and other functional compounds


such as capsaicin, gingerol, isothiocyanate, and chlorophyll. This
substance boosts metabolism energy consumption and helps in body
fat loss. 435

Studies show that consuming kimchi may help reduce heart disease
risk factors like high cholesterol and high blood sugar levels.

A small study found that eating fermented kimchi led to significant


reductions in total cholesterol, insulin, blood pressure, and fasting
blood sugar. 436, 437

Kimchi's an excellent source of antioxidants, so it may help protect


your cells against damage caused by oxidative stress. They are
associated with the prevention and treatment of several conditions,
including certain types of cancer, the common cold and mental
health. 438, 439, 440

All the above and many more properties make kimchi a nutritious,
healthy side dish.

However, kimchi and sauerkraut have a high sodium content. So


please be mindful by consuming it in moderation.

272
Kimchi is spicy and sour. It can be eaten by itself.

You can also consume it with a bowl of rice, on the side with egg,
chicken fish, savory pancakes or used in cooking to flavor stews and
noodle dishes.

273
M6: Superfoods
L32: Superfoods: Condiments: Black Pepper

B lack pepper, " King of spices," is the fruit of the black pepper

plant from the Piperaceae family. Different types of black peppers are
available having different colors. However, the most commonly
known peppers are black and white.

It is not just a flavor enhancer, adding a unique taste profile to our


food but it has many applications. It is used as medicine, as a
preservative, and in perfumes. The presence of oil cells in almost all
piper species places them in the group of aromatic plants.

It is a rich source of minerals like copper, manganese, iron, potassium,


phosphorus and vitamins like C, K, B6, and riboflavin. It also has a
dietary fiber with a moderate carb and protein ratio. 441

The chemical piperine is a major bioactive component present in


black pepper (and white pepper) that has numerous reported
physiological and drug-like actions. 442

Preliminary evidence in cell culture studies suggests that black


pepper contains antioxidant compounds and possesses
anti-inflammatory and antimicrobial properties. 443

274
The scientific studies suggest that black pepper may have health
benefits. For example, regular pepper consumption increases the
hydrochloric acid secretion in our stomach, leading to better
digestion. It also helps improve gastrointestinal conditions. 444

Preliminary cell culture studies suggest that black pepper contains


antioxidant constituents and possesses anti-inflammatory and
antimicrobial properties. 445

The rich depository of antioxidants found in black pepper reduces the


risk of heart diseases, nervous issues and cancer.

It also assuages the symptoms of aging like cognitive impairment and


degeneration due to the presence of piperine. 446

Black pepper may aid with fat loss. The outer layer of black pepper
pods aids in the breakdown of fat cells.

Thus, it is an excellent way to help you shed fat naturally while


eating flavourful food. 447, 448

It is effective for skincare and helps to cure vitiligo.

Research has also shown a positive response in patients with skin


cancer after administering a recommended dose of black pepper
daily. 449

Black pepper enhances the bioavailability of other food items like


turmeric, as it helps in transporting the nutrients from other herbs to
different parts of the body.

275
It makes the nutrients more readily accessible to our system.

It is advised to buy fresh black pepper pods from spice markets and
grind them on our own for full benefit and freshness. Adding a pinch
of black pepper to all our meals will help in improving our overall
health and well-being.

276
References

1. Fuller, M. F., & Crofts, R. M. J. (1977). The protein-sparing effect of carbohydrate.


British Journal of Nutrition, 38(3), 479–488.
https://doi.org/10.1079/bjn19770113, PMID: 588546,
https://pubmed.ncbi.nlm.nih.gov/588546/
2. Fuhrman, J. (2018). The Hidden Dangers of Fast and Processed Food. American
Journal of Lifestyle Medicine, 12(5), 375–381.
https://doi.org/10.1177/1559827618766483, PMCID: PMC6146358, PMID:
30283262, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146358/
3. Aundrea Parker 1 , Yeonsoo Kim 1, The Effect of Low Glycemic Index and
Glycemic Load Diets on Hepatic Fat Mass, Insulin Resistance, and Blood Lipid
Panels in Individuals with Nonalcoholic, Fatty Liver Disease, PMID: 31305201
DOI: 10.1089/met.2019.0038, https://pubmed.ncbi.nlm.nih.gov/31305201/
4. Wilcox, G. (2005). Insulin and Insulin Resistance. The Clinical Biochemist.
Reviews, 26(2), 19–39, PMCID: PMC1204764, PMID: 16278749,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1204764/
5. Zafar, M. I., Mills, K. E., Zheng, J., Regmi, A., Hu, S. Q., Gou, L., & Chen, L.-L.
(2019). Low-glycemic index diets as an intervention for diabetes: a systematic
review and meta-analysis. The American Journal of Clinical Nutrition, 110(4),
891–902. https://doi.org/10.1093/ajcn/nqz149,
https://academic.oup.com/ajcn/article-abstract/110/4/891/5543221?redirectedFr
om=fulltext
6. ‌Guoyao Wu, Dietary protein intake and human health, PMID: 26797090 DOI:
10.1039/c5fo01530h, Food Functions 2016 Mar,
https://pubmed.ncbi.nlm.nih.gov/26797090/
7. Robert R. Wolfe, Branched-chain amino acids and muscle protein synthesis in
humans: myth or reality?, Journal of the International Society of Sports Nutrition,
Published: 22 August 2017
https://jissn.biomedcentral.com/articles/10.1186/s12970-017-0184-9
8. R J Louard 1 , E J Barrett, R A Gelfand, Effect of infused branched-chain amino
acids on muscle and whole-body amino acid metabolism in man , Department of
Internal Medicine, Yale University School of Medicine, New Haven, Connecticut,

277
PMID: 2174312 DOI: 10.1042/cs0790457,
https://pubmed.ncbi.nlm.nih.gov/2174312/
9. Eva Blomstrand, Jörgen Eliasson, Håkan K R Karlsson, Rickard Köhnke,
Branched-chain amino acids activate key enzymes in protein synthesis after
physical exercise, PMID: 16365096 DOI: 10.1093/jn/136.1.269S Affiliation
Department of Surgical Science, Karolinska Institutet, Stockholm, Sweden.
https://pubmed.ncbi.nlm.nih.gov/16365096/
10.Do I Need to Worry About Eating ‘Complete’ Proteins?, Health Essentials,
Cleveland, Clinic, March 12, 2019,
https://health.clevelandclinic.org/do-i-need-to-worry-about-eating-complete-pr
oteins/
11.Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids,
Cholesterol, Protein, and Amino Acids (2005), The National Academies Press,
https://www.nap.edu/read/10490/chapter/1
12.Thomas DT, Erdman KA, Burke LM. American College of Sports Medicine Joint
Position. Statement. Nutrition and Athletic Performance. Med Sci Sports Exerc.
2016, Mar;48(3):543-68. doi: 10.1249/MSS.0000000000000852, Erratum in:
Med Sci Sports, Exerc. 2017 Jan;49(1):222. PMID: 26891166,
https://pubmed.ncbi.nlm.nih.gov/26891166/
13.Kreider RB, Campbell B. Protein for exercise and recovery. Phys Sportsmed.
2009. Jun;37(2):13-21. doi: 10.3810/psm.2009.06.1705. PMID: 20048505,
https://pubmed.ncbi.nlm.nih.gov/20048505
14.Ralf Jäger, Chad M Kerksick, Bill I Campbell, Paul J Cribb, Shawn D Wells, Tim M
Skwiat, Martin Purpura, Tim N Ziegenfuss, Arny A Ferrando, Shawn M Arent,
Abbie E Smith-Ryan, Jeffrey R Stout, Paul J Arciero, Michael J Ormsbee, Lem W
Taylor, Colin D Wilborn, Doug S Kalman, Richard B Kreider, Darryn S
Willoughby, Jay R Hoffman, Jamie L Krzykowski, Jose Antonio, International
Society of Sports Nutrition Position Stand: protein and exercise, PMID:
28642676 PMCID: PMC5477153 DOI: 10.1186/s12970-017-0177-8,
https://pubmed.ncbi.nlm.nih.gov/28642676/
15.Morton RW, Murphy KT, McKellar SR, Schoenfeld BJ, Henselmans M, Helms E,
Aragon. AA, Devries MC, Banfield L, Krieger JW, Phillips SM. A systematic
review, meta-analysis and meta-regression of the effect of protein
supplementation on resistance training-induced gains in muscle mass and
strength in healthy adults. Br J Sports Med. 2018 Mar;52(6):376-384. doi:
10.1136/bjsports-2017-097608. Epub 2017 Jul 11. Erratum in: Br J Sports Med.

278
2020 Oct;54(19):e7. PMID: 28698222; PMCID: PMC5867436,
https://pubmed.ncbi.nlm.nih.gov/28698222
16.Hoffman JR, Ratamess NA, Kang J, Falvo MJ, Faigenbaum AD. Effect of protein
intake on strength, body composition and endocrine changes in strength/power
athletes. J Int Soc Sports Nutr. 2006;3(2):12-18. Published 2006 Dec 13.
doi:10.1186/1550-2783-3-2-12, PMCID: PMC2129168 PMID: 18500968,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2129168
17.Calder, P. C. (2015). Functional Roles of Fatty Acids and Their Effects on Human
Health. JPEN. Journal of Parenteral and Enteral Nutrition, 39(1 Suppl), 18S32S,
https://doi.org/10.1177/0148607115595980, PMID: 26177664,
https://pubmed.ncbi.nlm.nih.gov/26177664/
18.Bess Dawson-Hughes, Susan S Harris, Alice H Lichtenstein, Gregory
Dolnikowski, Nancy J Palermo, Helen Rasmussen, Dietary fat increases vitamin
D-3 absorption, PMID: 25441954 DOI: 10.1016/j.jand.2014.09.014,
https://pubmed.ncbi.nlm.nih.gov/25441954/
19.Esposito, K., Marfella, R., Ciotola, M., Di Palo, C., Giugliano, F., Giugliano, G.,
D’Armiento, M., D’Andrea, F., & Giugliano, D. (2004). Effect of a
Mediterranean-Style Diet on Endothelial Dysfunction and Markers of Vascular
Inflammation in the Metabolic Syndrome. JAMA, 292(12), 1440.
https://doi.org/10.1001/jama.292.12.1440,
https://pubmed.ncbi.nlm.nih.gov/15383514/
20.Mata, P., Garrido, J. A., Ordovas, J. M., Blazquez, E., Alvarez-Sala, L. A., Rubio, M.
J., Alonso, R., & de Oya, M. (1992). Effect of dietary monounsaturated fatty acids
on plasma lipoproteins and apolipoproteins in women. The American Journal of
Clinical Nutrition, 56(1), 77–83, https://doi.org/10.1093/ajcn/56.1.77, PMID:
1609766, https://www.ncbi.nlm.nih.gov/pubmed/1609766
21.Appel, L. J., Sacks, F. M., Carey, V. J., Obarzanek, E., Swain, J. F., Miller, E. R.,
Conlin, P. R., Erlinger, T. P., Rosner, B. A., Laranjo, N. M., Charleston, J., McCarron,
P., Bishop, L. M., & OmniHeart Collaborative Research Group. (2005). Effects of
protein, monounsaturated fat, and carbohydrate intake on blood pressure and
serum lipids: results of the OmniHeart randomized trial. JAMA, 294(19),
2455–2464, https://doi.org/10.1001/jama.294.19.2455, PMID: 16287956,
https://www.ncbi.nlm.nih.gov/pubmed/16287956
22.Ebrahimi, M., Ghayour-Mobarhan, M., Rezaiean, S., Hoseini, M., Parizade, S. M. R.,
Farhoudi, F., Hosseininezhad, S. J., Tavallaei, S., Vejdani, A., Azimi-Nezhad, M.,
Shakeri, M. T., Rad, M. A., Mobarra, N., Kazemi-Bajestani, S. M. R., & Ferns, G. A.
A. (2009). Omega-3 fatty acid supplements improve the cardiovascular risk
profile of subjects with metabolic syndrome, including markers of inflammation

279
and auto-immunity. Acta Cardiologica, 64(3), 321–327.
https://doi.org/10.2143/AC.64.3.2038016,PMID: 19593941,
www.ncbi.nlm.nih.gov/pubmed/19593941
23.DiNicolantonio, J. J., & O’Keefe, J. H. (2018). Importance of maintaining a low
omega–6/omega–3 ratio for reducing inflammation. Open Heart, 5(2), e000946.
https://doi.org/10.1136/openhrt-2018-000946, PMCID: PMC6269634, PMID:
30564378, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269634/
24.Robinson, J. G., Ijioma, N., & Harris, W. (2010). Omega-3 Fatty Acids and
Cognitive Function in Women. Women’s Health, 6(1), 119–134.
https://doi.org/10.2217/whe.09.75, PMCID: PMC2826215, NIHMSID:
NIHMS171817, PMID: 20088735,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826215/
25.Bradbury, J. (2011). Docosahexaenoic Acid (DHA): An Ancient Nutrient for the
Modern Human Brain. Nutrients, 3(5), 529–554.
https://doi.org/10.3390/nu3050529, PMCID: PMC3257695, PMID: 22254110,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257695/
26.Dhaka, V., Gulia, N., Ahlawat, K. S., & Khatkar, B. S. (2011). Trans fats—sources,
health risks and alternative approach - A review. Journal of Food Science and
Technology, 48(5), 534–541. https://doi.org/10.1007/s13197-010-0225-8,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551118/
27.Center for Food Safety and Applied Nutrition. (2018). Final Determination
Regarding Partially Hydrogenated Oils. U.S. Food and Drug Administration.
https://www.fda.gov/food/food-additives-petitions/final-determination-regardin
g-partia lly-hydrogenated-oils-removing-trans-fat
28.M I Dawson, The importance of vitamin A in nutrition , PMID: 10637381 DOI:
10.2174/1381612003401190, https://pubmed.ncbi.nlm.nih.gov/10637381/
29.Sommer, A. (2008). Vitamin A Deficiency and Clinical Disease: An Historical
Overview. The Journal of Nutrition, 138(10), 1835–1839.
https://doi.org/10.1093/jn/138.10.1835,
https://academic.oup.com/jn/article/138/10/1835/4669996
30.Mimi Chiu, Alexander Dillon, Stephanie Watson, Vitamin A deficiency and
xerophthalmia in children of a developed country, PMID: 27439630 DOI:
10.1111/jpc.13243, https://pubmed.ncbi.nlm.nih.gov/27439630/
31.Aguayo, V. M., & Baker, S. K. (2005). Vitamin A Deficiency and Child Survival in
Sub-Saharan Africa: A Reappraisal of Challenges and Opportunities. Food and
Nutrition Bulletin, 26(4), 348–355.
https://doi.org/10.1177/156482650502600404‌, PMID: 16465981,
https://pubmed.ncbi.nlm.nih.gov/16465981/
32.Lartey, A. (2008). Maternal and child nutrition in Sub-Saharan Africa: challenges

280
and interventions. Proceedings of the Nutrition Society, 67(1), 105–108.
https://doi.org/10.1017/s0029665108006083, PMID: 18234138,
‌https://pubmed.ncbi.nlm.nih.gov/18234138/
33.Aguayo, V. M., Kahn, S., Ismael, C., & Meershoek, S. (2005). Vitamin A deficiency
and child mortality in Mozambique. Public Health Nutrition, 8(1), 29–31.
https://doi.org/10.1079/phn2005664,PMID: 15705242,
https://pubmed.ncbi.nlm.nih.gov/157052
34.Christakos, S., Dhawan, P., Porta, A., Mady, L. J., & Seth, T. (2011). Vitamin D and
intestinal calcium absorption. Molecular and Cellular Endocrinology, 347(1-2),
25–29. https://doi.org/10.1016/j.mce.2011.05.038, PMCID: PMC3405161,
NIHMSID: NIHMS306628, PMID: 21664413,
‌https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405161/
35.Laird, E., Ward, M., McSorley, E., Strain, J. J., & Wallace, J. (2010). Vitamin D and
Bone Health; Potential Mechanisms. Nutrients, 2(7), 693–724.
https://doi.org/10.3390/nu2070693, PMCID: PMC3257679, PMID: 22254049
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257679/
36.Garland, C. F., Garland, F. C., Gorham, E. D., Lipkin, M., Newmark, H., Mohr, S. B.,
& Holick, M. F. (2006). The Role of Vitamin D in Cancer Prevention. American
Journal of Public Health, 96(2), 252–261.
https://doi.org/10.2105/ajph.2004.045260 ‌, PMCID: PMC1470481, PMID:
16380576, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470481/
37.Sahay, M., & Sahay, R. (2012). Rickets-vitamin D deficiency and dependency.
Indian Journal of Endocrinology and Metabolism, 16(2), 164.
https://doi.org/10.4103/2230-8210.93732‌, PMCID: PMC3313732, PMID:
22470851, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313732/
38.https://fabulousbody.com/over-a-billion-people-worldwide-are-vitamin-d-defici
ent-are-you-one-of-them/
39.Rizvi, S., Raza, S. T., Ahmed, F., Ahmad, A., Abbas, S., & Mahdi, F. (2014). The
role of vitamin e in human health and some diseases. Sultan Qaboos University
Medical Journal, 14(2), e157-65, PMCID: PMC3997530, PMID: 24790736,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997530/
40.Didem Pekmezci, Vitamin E and immunity, PMID: 21419272 DOI:
10.1016/B978-0-12-386960-9.00008-3,
https://pubmed.ncbi.nlm.nih.gov/21419272/
41.Boston, 677 H. A., & Ma 02115 +1495‑1000. (2012, September 18). Vitamin K.
The Nutrition Source, https://www.hsph.harvard.edu/nutritionsource/vitamin-k/
42.Bügel, S. (2003). Vitamin K and bone health. The Proceedings of the Nutrition
Society, 62(4), 839–843, https://doi.org/10.1079/PNS2003305‌, PMID:

281
15018483, ‌https://pubmed.ncbi.nlm.nih.gov/15018483/
43.Wen, L., Chen, J., Duan, L., & Li, S. (2018). Vitamin K‑dependent proteins
involved in bone and cardiovascular health (Review). Molecular Medicine
Reports. https://doi.org/10.3892/mmr.2018.8940, PMCID: PMC6059683, PMID:
29749440, ‌https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059683/
44.‌Eden, R. E., & Coviello, J. M. (2020). Vitamin K Deficiency. PubMed; StatPearls
Publishing.
https://www.ncbi.nlm.nih.gov/books/NBK536983/#:~:text=Vitamin%20K%20ref
ers%20to%20a
45.Thiamine deficiency and its prevention and control in major emergencies. (n.d.).
https://www.who.int/nutrition/publications/en/thiamine_in_emergencies_eng.pdf
46.Gibson, G. E., Hirsch, J. A., Fonzetti, P., Jordon, B. D., Cirio, R. T., & Elder, J. (2016).
Vitamin B1 (thiamine) and dementia. Annals of the New York Academy of
Sciences, 1367(1), 21–30. https://doi.org/10.1111/nyas.13031, PMID:
26971083, PMCID: PMC4846521, ‌https://pubmed.ncbi.nlm.nih.gov/26971083/
47.DiNicolantonio, J. J., Liu, J., & O’Keefe, J. H. (2018). Thiamine and Cardiovascular
Disease: A Literature Review. Progress in Cardiovascular Diseases, 61(1),
27–32. https://doi.org/10.1016/j.pcad.2018.01.009, PMID: 29360523,
https://pubmed.ncbi.nlm.nih.gov/29360523/
48.John T Pinto, Janos Zempleni, Riboflavin, PMCID: PMC5015041,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015041/
49.Donald L Bissett, John E Oblong, Cynthia A Berge, Niacinamide: A B vitamin that
improves aging facial skin appearance, PMID: 16029679 DOI:
10.1111/j.1524-4725.2005.31732, https://pubmed.ncbi.nlm.nih.gov/16029679/
50. Rosemary A Fricker, Emma L Green, Stuart I Jenkins, Síle M Griffin, The
Influence of Nicotinamide on Health and Disease in the Central Nervous System,
PMID: 29844677 PMCID: PMC5966847 DOI: 10.1177/1178646918776658,
https://pubmed.ncbi.nlm.nih.gov/29844677/
51.Malkanthi Evans , John A Rumberger, Isao Azumano , Joseph J Napolitano,
Danielle Citrolo , Toshikazu Kamiya, Pantethine, a derivative of vitamin B5,
favorably alters total, LDL and non-HDL cholesterol in low to moderate
cardiovascular risk subjects eligible for statin therapy: a triple-blinded placebo
and diet-controlled investigation, PMID: 24600231 PMCID: PMC3942300 DOI:
10.2147/VHRM.S57116, https://pubmed.ncbi.nlm.nih.gov/24600231
52.L C Rall, S N Meydani, Vitamin B6 and immune competence, PMID: 8302491
DOI: 10.1111/j.1753-4887.1993.tb03109.x,
https://pubmed.ncbi.nlm.nih.gov/8302491/
53.Vitamin B6: MedlinePlus Medical Encyclopedia. (n.d.). Medlineplus.gov.

282
https://medlineplus.gov/ency/article/002402.htm ‌
54.Bender, D. A. (1989). Vitamin B6 requirements and recommendations. European
Journal of Clinical Nutrition, 43(5), 289–30, PMID: 2661220,
https://pubmed.ncbi.nlm.nih.gov/2661220/‌
55.Vitamin B-6: Benefits, dosage, food sources, and deficiency symptoms. (n.d.).
Www.medicalnewstoday.com.
https://www.medicalnewstoday.com/articles/219662
56.Biotin – Vitamin B7. (2019, July 24). The Nutrition Source.
https://www.hsph.harvard.edu/nutritionsource/biotin-vitamin-b7/
57.Naderi, N., & House, J. D. (2018). Recent Developments in Folate Nutrition.
Advances in Food and Nutrition Research, 195–213.
https://doi.org/10.1016/bs.afnr.2017.12.006, PMID: 29477222,
https://pubmed.ncbi.nlm.nih.gov/29477222/
58.Folate (Folic Acid) – Vitamin B9. (2012, September 18). The Nutrition Source.
https://www.hsph.harvard.edu/nutritionsource/folic-acid/
59.Green, R., & Datta Mitra, A. (2017). Megaloblastic Anemias. Medical Clinics of
North America, 101(2), 297–317. https://doi.org/10.1016/j.mcna.2016.09.013,
PMID: 28189172, https://pubmed.ncbi.nlm.nih.gov/28189172/
60.Gille, D., & Schmid, A. (2015). Vitamin B12 in meat and dairy products. Nutrition
Reviews, 73(2), 106–115. https://doi.org/10.1093/nutrit/nuu011,
https://pubmed.ncbi.nlm.nih.gov/26024497/
61.Anitra C Carr, Silvia Maggini, Vitamin C and Immune Function, PMID: 29099763
PMCID: PMC5707683 DOI: 10.3390/nu9111211,
https://pubmed.ncbi.nlm.nih.gov/29099763/
62.Sr, L., & Jd, C. (1980). Interaction of Vitamin C and Iron. Annals of the New York
Academy of Sciences, DOI: 10.1111/j.1749-6632.1980.tb21325.x, PMID:
6940487, https://pubmed.ncbi.nlm.nih.gov/6940487/
63.Velandia, B., Centor, R. M., McConnell, V., & Shah, M. (2008). Scurvy Is Still
Present in Developed Countries. Journal of General Internal Medicine, 23(8),
1281–1284, https://doi.org/10.1007/s11606-008-0577-1, PMID: 18459013,
PMCID: PMC2517958, https://pubmed.ncbi.nlm.nih.gov/18459013/
64.Jane Higdon, Victoria J. Drake, Barbara Delage, Connie M. Weaver, Linus Pauling
Institute, Calcium, Micronutrient Information Center,
https://lpi.oregonstate.edu/mic/minerals/calcium
65.Calcium. (2014, April 22). Linus Pauling Institute.
https://lpi.oregonstate.edu/mic/minerals/calcium
66.Office of Dietary Supplements - Phosphorus. (2017). Nih.gov.
https://ods.od.nih.gov/factsheets/Phosphorus-HealthProfessional/

283
67.Calvo, M. S., & Lamberg-Allardt, C. J. (2015). Phosphorus. Advances in Nutrition,
6(6), 860–862. https://doi.org/10.3945/an.115.008516, PMCID: PMC4642415,
PMID: 26567206, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642415/
68.Dunn, J., & Grider, M. H. (2020). Physiology, Adenosine Triphosphate (ATP).
PubMed; StatPearls Publishing.
https://www.ncbi.nlm.nih.gov/books/NBK553175/
69.Vernon, W. B. (1988). The role of magnesium in nucleic-acid and protein
metabolism. Magnesium, 7(5-6), 234–248, PMID: 2472534,
https://pubmed.ncbi.nlm.nih.gov/2472534/,
70.Shrimanker, I., & Bhattarai, S. (2021). Electrolytes. PubMed; StatPearls
Publishing., PMID: 31082167, https://pubmed.ncbi.nlm.nih.gov/31082167/
71.Berend, K., van Hulsteijn, L. H., & Gans, R. O. B. (2012). Chloride: The queen of
electrolytes? European Journal of Internal Medicine, 23(3), 203–211.
https://doi.org/10.1016/j.ejim.2011.11.013, PMID: 22385875,
https://pubmed.ncbi.nlm.nih.gov/22385875/
72.Carmen Andrea Pfortmueller, Dominik Uehlinger, Stephan von Haehling,3 and
Joerg Christian Schefold, Serum chloride levels in critical illness—the hidden
story, PMCID: PMC5899079, PMID: 29654387,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899079/
73.Jennifer S Hanberg , Veena Rao, Jozine M Ter Maaten , Olga Laur, Meredith A
Brisco, F Perry Wilson, Justin L Grodin , Mahlet Assefa , J Samuel Broughton,
Noah J Planavsky , Tariq Ahmad, Lavanya Bellumkonda , W H Wilson Tang,
Chirag R Parikh , Jeffrey M Testani, Hypochloremia and Diuretic Resistance in
Heart Failure: Mechanistic Insights , PMID: 27507113 PMCID: PMC4988527
DOI: 10.1161/CIRCHEARTFAILURE.116.003180,
https://pubmed.ncbi.nlm.nih.gov/27507113/
74.Morrison, G. (1990). Serum Chloride (H. K. Walker, W. D. Hall, & J. W. Hurst,
Eds.). PubMed; Butterworths. https://www.ncbi.nlm.nih.gov/books/NBK309/
75.Potassium deficiency (hypokalemia): Symptoms and treatment. (n.d.).
Www.medicalnewstoday.com.
https://www.medicalnewstoday.com/articles/325065
76.Lim, S. (2007). Approach to hypokalemia. Acta Medica Indonesiana, 39(1),
56–64, PMID: 17297212 https://pubmed.ncbi.nlm.nih.gov/17297212/
77.Feng, M., Tang, B., Liang, S. H., & Jiang, X. (2016). Sulfur Containing Scaffolds in
Drugs: Synthesis and Application in Medicinal Chemistry. Current Topics in
Medicinal Chemistry, 16(11), 1200–1216, PMCID: PMC4877035, NIHMSID:
NIHMS785127, PMID: 26369815,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877035/

284
78.Abbaspour, N., Hurrell, R., & Kelishadi, R. (2014). Review on iron and its
importance for human health. Journal of Research in Medical Sciences : The
Official Journal of Isfahan University of Medical Sciences, 19(2), 164–174,
PMCID: PMC3999603, PMID: 24778671,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999603/
79.Goddard, A. F., James, M. W., McIntyre, A. S., & Scott, B. B. (2011). Guidelines for
the management of iron deficiency anaemia. Gut, 60(10), 1309–1316.
https://doi.org/10.1136/gut.2010.228874, PMID: 21561874,
https://pubmed.ncbi.nlm.nih.gov/21561874/
80.Cleveland Clinic. (2020). Anemia: Symptoms, Types, Causes, Risks, Treatment &
Management. Cleveland Clinic.
https://my.clevelandclinic.org/health/diseases/3929-anemia
81.Ananda S Prasad, Zinc in Human Health: Effect of Zinc on Immune Cells, PMCID:
PMC2277319, PMID: 18385818, Published online 2008 Apr 3. doi:
10.2119/2008-00033.Prasad,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2277319/
82.Blasiak, J., Pawlowska, E., Chojnacki, J., Szczepanska, J., Chojnacki, C., &
Kaarniranta, K. (2020). Zinc and Autophagy in Age-Related Macular
Degeneration. International Journal of Molecular Sciences, 21(14), 4994.
https://doi.org/10.3390/ijms21144994, PMCID: PMC7404247, PMID:
32679798, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404247/
83.Muhamed, P. K., & Vadstrup, S. (2014). [Zinc is the most important trace
element]. Ugeskrift for Laeger, 176(5), PMID: 25096007,
https://pubmed.ncbi.nlm.nih.gov/25096007/
84.National Institutes of Health. (2017). Office of Dietary Supplements - Copper.
Nih.gov, https://ods.od.nih.gov/factsheets/Copper-HealthProfessional/
85.Wazir, S. M., & Ghobrial, I. (2017). Copper deficiency, a new triad: anemia,
leucopenia, and myeloneuropathy. Journal of Community Hospitaiabetesl
Internal Medicine Perspectives, 7(4), 265–268,
https://doi.org/10.1080/20009666.2017.1351289, PMCID: PMC5637704,
PMID: 29046759, ‌https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637704/
86.Longman Li, Xiaobo Yang, The Essential Element Manganese, Oxidative Stress,
and Metabolic Diseases: Links and Interactions,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907490/
87.Aschner, M., & Erikson, K. (2017). Manganese. Advances in Nutrition: An
International Review Journal, 8(3), 520–521.
https://doi.org/10.3945/an.117.015305,
https://academic.oup.com/advances/article/8/3/520/4616699

285
88.Ventura, M., Melo, M., & Carrilho, F. (2017). Selenium and Thyroid Disease: From
Pathophysiology to Treatment. International Journal of Endocrinology, 2017,
1–9. https://doi.org/10.1155/2017/1297658, PMCID: PMC5307254, PMID:
28255299, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307254/
89.Rayman, M. P. (2012). Selenium and human health. Lancet (London, England),
379(9822), 1256–1268. https://doi.org/10.1016/S0140-6736(11)61452-9,
PMID: 22381456, https://pubmed.ncbi.nlm.nih.gov/22381456/
90.Avery, J., & Hoffmann, P. (2018). Selenium, Selenoproteins, and Immunity.
Nutrients, 10(9), 1203. https://doi.org/10.3390/nu10091203, PMCID:
PMC6163284, PMID: 30200430,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163284/
91.A Scientific Review: The Role of Chromium in Insulin Resistance. (2004). The
Diabetes Educator, PMID: 15208835,
https://pubmed.ncbi.nlm.nih.gov/15208835/
92.Anderson, R. A. (2000). Chromium in the prevention and control of diabetes.
Diabetes & Metabolism, 26(1), 22–27,PMID: 10705100,
https://pubmed.ncbi.nlm.nih.gov/10705100/
93.Chromium. (2014, April 22). Linus Pauling Institute.
https://lpi.oregonstate.edu/mic/minerals/chromium#deficiency ‌
94.Kapil, U. (2007). Health consequences of iodine deficiency. Sultan Qaboos
University Medical Journal, 7(3), 267–272, PMCID: PMC3074887, PMID:
21748117, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074887/
95.Office of Dietary Supplements - Molybdenum. (n.d.). Ods.od.nih.gov. Retrieved
July 27, 2021, from
https://ods.od.nih.gov/factsheets/Molybdenum-HealthProfessional/#en1
96.Molybdenum. (2014, April 23). Linus Pauling Institute.
https://lpi.oregonstate.edu/mic/minerals/molybdenum ‌
97.Sardesai, V. M. (1993). Molybdenum: An Essential Trace Element. Nutrition in
Clinical Practice, 8(6), 277–281,
https://doi.org/10.1177/0115426593008006277, PMID: 8302261,
https://pubmed.ncbi.nlm.nih.gov/8302261/
98.Czarnek, K., Terpiłowska, S., & Siwicki, A. K. (2015). Review paper Selected
aspects of the action of cobalt ions in the human body. Central European Journal
of Immunology, 2, 236–242. https://doi.org/10.5114/ceji.2015.52837, PMID:
26557039, PMCID: PMC4637398, https://pubmed.ncbi.nlm.nih.gov/26557039/
99.Barton Health | Health Library | Staywell Health Library | Cobalt. (n.d.).
Www.bartonhealth.org. Retrieved August 17, 2021, from
https://www.bartonhealth.org/tahoe/health-library/cobalt-5638.aspx?iid=19_Co

286
balt
100. Smith, S. E., & Loosli, J. K. (1957). Cobalt and Vitamin 12 in Ruminant
Nutrition: A Review. Journal of Dairy Science, 40(10), 1215–1227.
https://doi.org/10.3168/jds.S0022-0302(57)94618-0 ‌,
https://www.sciencedirect.com/science/article/pii/S0022030257946180
101. Yang, J. (2012). Effect of dietary fiber on constipation: A meta analysis. World
Journal of Gastroenterology, 18(48), 7378,
https://doi.org/10.3748/wjg.v18.i48.7378, PMCID: PMC3544045, PMID:
23326148, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544045/
102. Rebello, C. J., O’Neil, C. E., & Greenway, F. L. (2016). Dietary fiber and satiety:
the effects of oats on satiety. Nutrition Reviews, 74(2), 131–147.
https://doi.org/10.1093/nutrit/nuv063, PMID: 26724486, PMCID: PMC4757923,
https://pubmed.ncbi.nlm.nih.gov/26724486/ ‌
103. Finn, K., Jacquier, E., Kineman, B., Storm, H., & Carvalho, R. (2019). Nutrient
intakes and sources of fiber among children with low and high dietary fiber
intake: the 2016 feeding infants and toddlers study (FITS), a cross-sectional
survey. BMC Pediatrics, 19(1). https://doi.org/10.1186/s12887-019-1822-y,
PMCID: PMC6859612, PMID: 31739781,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859612/
104. McRae, M. P. (2017). Dietary Fiber Is Beneficial for the Prevention of
Cardiovascular Disease: An Umbrella Review of Meta-analyses. Journal of
Chiropractic Medicine, 16(4), 289–299.
https://doi.org/10.1016/j.jcm.2017.05.005, PMCID: PMC5731843, PMID:
29276461, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731843/
105. Hadhazy, A. (2010, February 12). Think Twice: How the Gut’s “Second Brain”
Influences Mood and Well-Being. Scientific American,
https://www.scientificamerican.com/article/gut-second-brain/
106. Breit, S., Kupferberg, A., Rogler, G., & Hasler, G. (2018). Vagus Nerve as
Modulator of the Brain–Gut Axis in Psychiatric and Inflammatory Disorders.
Frontiers in Psychiatry, 9(44). https://doi.org/10.3389/fpsyt.2018.00044, PMCID:
PMC5859128, PMID: 29593576,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859128/
107. Vighi, G., Marcucci, F., Sensi, L., Di Cara, G., & Frati, F. (2008). Allergy and the
gastrointestinal system. Clinical & Experimental Immunology, 153, 3–6.
https://doi.org/10.1111/j.1365-2249.2008.03713.x, PMCID: PMC2515351,
PMID: 18721321, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515351/
108. Yano, J. M., Yu, K., Donaldson, G. P., Shastri, G. G., Ann, P., Ma, L., Nagler, C.
R., Ismagilov, R. F., Mazmanian, S. K., & Hsiao, E. Y. (2015). Indigenous bacteria

287
from the gut microbiota regulate host serotonin biosynthesis. Cell, 161(2),
264–276. https://doi.org/10.1016/j.cell.2015.02.047, PMCID: PMC4393509,
NIHMSID: NIHMS669675, PMID: 25860609,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393509/
109. Conly, J. M., & Stein, K. (1992). The production of menaquinones (vitamin K2)
by intestinal bacteria and their role in maintaining coagulation homeostasis.
Progress in Food & Nutrition Science, 16(4), 307–343, PMID: 1492156,
https://pubmed.ncbi.nlm.nih.gov/1492156/
110. ‌Rossi, M., Amaretti, A., & Raimondi, S. (2011). Folate Production by Probiotic
Bacteria. Nutrients, 3(1), 118–134. https://doi.org/10.3390/nu3010118, PMCID:
PMC3257725, PMID: 22254078,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257725/
111. Morrison, D. J., & Preston, T. (2016). Formation of short chain fatty acids by
the gut microbiota and their impact on human metabolism. Gut Microbes, 7(3),
189–200. https://doi.org/10.1080/19490976.2015.1134082, PMCID:
PMC4939913, PMID: 26963409,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939913/
112. ‌Morowitz, M. J., Carlisle, E. M., & Alverdy, J. C. (2011). Contributions of
Intestinal Bacteria to Nutrition and Metabolism in the Critically Ill. Surgical
Clinics of North America, 91(4), 771–785.
https://doi.org/10.1016/j.suc.2011.05.001, PMCID: PMC3144392, NIHMSID:
NIHMS296280, PMID: 21787967,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144392/
113. O’Mahony, S. M., Clarke, G., Borre, Y. E., Dinan, T. G., & Cryan, J. F. (2015).
Serotonin, tryptophan metabolism and the brain-gut-microbiome axis.
Behavioural Brain Research, 277, 32–48.
https://doi.org/10.1016/j.bbr.2014.07.027, PMID: 25078296,
https://pubmed.ncbi.nlm.nih.gov/25078296/
114. Your Gut Can Influence How You Feel: It All Starts with GABA and Serotonin.
(2011, December 13). The Body Ecology.
https://bodyecology.com/articles/your-gut-can-influence-how-you-feel-it-all-sta
rts-with-serotonin/
115. Reigstad, C. S., Salmonson, C. E., Rainey, J. F., Szurszewski, J. H., Linden, D. R.,
Sonnenburg, J. L., Farrugia, G., & Kashyap, P. C. (2015). Gut microbes promote
colonic serotonin production through an effect of short-chain fatty acids on
enterochromaffin cells. The FASEB Journal, 29(4), 1395–1403.
https://doi.org/10.1096/fj.14-259598,
https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.14-259598

288
116. Núria Macha, Dolors Fuster-Botellaa, Endurance exercise and gut microbiota:
A review, PMCID: PMC6188999, PMID: 30356594,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188999/
117. Zhang, Y.-J., Li, S., Gan, R.-Y., Zhou, T., Xu, D.-P., & Li, H.-B. (2015). Impacts of
Gut Bacteria on Human Health and Diseases. International Journal of Molecular
Sciences, 16(12), 7493–7519. https://doi.org/10.3390/ijms16047493, PMCID:
PMC4425030, PMID: 25849657,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425030/
118. Patterson, E., Ryan, P. M., Cryan, J. F., Dinan, T. G., Ross, R. P., Fitzgerald, G.
F., & Stanton, C. (2016). Gut microbiota, obesity and diabetes. Postgraduate
Medical Journal, 92(1087), 286–300.
https://doi.org/10.1136/postgradmedj-2015-133285, PMID: 26912499,
https://pubmed.ncbi.nlm.nih.gov/26912499/
119. Life, F. U. (2019, October 1). 6 Benefits of Drinking Water: Why You Really
Need to Stay Hydrated! BrainMD Health Blog.
https://brainmd.com/blog/6-amazing-health-benefits-of-drinking-water/
120. Stookey, J. D., Constant, F., Popkin, B. M., & Gardner, C. D. (2008). Drinking
Water Is Associated With Weight Loss in Overweight Dieting Women
Independent of Diet and Activity. Obesity, 16(11), 2481–2488.
https://doi.org/10.1038/oby.2008.409, PMID: 18787524,
https://pubmed.ncbi.nlm.nih.gov/18787524/
121. Boschmann, M., Steiniger, J., Hille, U., Tank, J., Adams, F., Sharma, A. M.,
Klaus, S., Luft, F. C., & Jordan, J. (2003). Water-induced thermogenesis. The
Journal of Clinical Endocrinology and Metabolism, 88(12), 6015–6019.
https://doi.org/10.1210/jc.2003-030780, PMID: 14671205,
https://pubmed.ncbi.nlm.nih.gov/14671205/
122. Vij, V. A. (2013). Effect of “Water Induced Thermogenesis” on Body Weight,
Body Mass Index and Body Composition of Overweight Subjects. JOURNAL of
CLINICAL and DIAGNOSTIC RESEARCH.
https://doi.org/10.7860/jcdr/2013/5862.3344, PMID: 24179891, PMCID:
PMC3809630, https://pubmed.ncbi.nlm.nih.gov/24179891/
123. Vij, V. A. K., & Joshi, A. S. (2014). Effect of excessive water intake on body
weight, body mass index, body fat, and appetite of overweight female
participants. Journal of Natural Science, Biology, and Medicine, 5(2), 340–344.
https://doi.org/10.4103/0976-9668.136180, PMID: 25097411, PMCID:
PMC4121911, https://pubmed.ncbi.nlm.nih.gov/25097411/
124. Mowbray, J. (2002). A drink to your health! Nature, 420(6917), 742–743.
https://doi.org/10.1038/420742a

289
‌ ttp://www.dining.ucla.edu/housing_site/dining/SNAC_pdf/DrinkToYourHealth.p
h
df
125. Sinha, S. (2017, May 8). Water, water everywhere. The Hindu.
https://www.thehindu.com/sci-tech/health/water-water-everywhere/article1840
9340.ece
126. Chang, C.-Y., Der-Shin Ke, & Jen-Yin Chen. (2009, December). Essential fatty
acids and human brain. ResearchGate; unknown,
https://www.researchgate.net/publication/42438067_Essential_fatty_acids_and
_human _brain
127. Querques, G., Forte, R., & Souied, E. H. (2011). Retina and Omega-3. Journal
of Nutrition and Metabolism, 2011, 1–12. https://doi.org/10.1155/2011/748361,
PMCID: PMC3206354, PMID: 22175009,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206354/
128. Després, J.-P. (2012). Body Fat Distribution and Risk of Cardiovascular
Disease. Circulation, 126(10), 1301–1313.
https://doi.org/10.1161/circulationaha.111.067264,
https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.111.067264
129. Gardner, C. D., Trepanowski, J. F., Del Gobbo, L. C., Hauser, M. E., Rigdon, J.,
Ioannidis, J. P. A., Desai, M., & King, A. C. (2018). Effect of Low-Fat vs
Low-Carbohydrate Diet on 12-Month Weight Loss in Overweight Adults and
the Association With Genotype Pattern or Insulin Secretion. JAMA, 319(7), 667.
https://doi.org/10.1001/jama.2018.0245
130. ‌Ancel Keys - Seven Countries Study | The first study to relate diet with
cardiovascular disease. (2012). Seven Countries Study | the First Study to Relate
Diet with Cardiovascular Disease.
https://www.sevencountriesstudy.com/about-the-study/investigators/ancel-keys/
131. ‌Siri-Tarino, P. W., Sun, Q., Hu, F. B., & Krauss, R. M. (2010). Meta-analysis of
prospective cohort studies evaluating the association of saturated fat with
cardiovascular disease. The American Journal of Clinical Nutrition, 91(3),
535–546. https://doi.org/10.3945/ajcn.2009.27725,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824152/
132. ‌Malhotra, A. (2013). Saturated fat is not the major issue. BMJ, 347(oct22 1),
f6340–f6340. https://doi.org/10.1136/bmj.f6340,
https://www.bmj.com/content/347/bmj.f6340
133. Chowdhury, R., Warnakula, S., Kunutsor, S., Crowe, F., Ward, H. A., Johnson,
L., Franco, O. H., Butterworth, A. S., Forouhi, N. G., Thompson, S. G., Khaw, K.-T.,
Mozaffarian, D., Danesh, J., & Di Angelantonio, E. (2014). Association of dietary,
circulating, and supplement fatty acids with coronary risk: a systematic review
and meta-analysis. Annals of Internal Medicine, 160(6), 398–406.

290
https://doi.org/10.7326/M13-1788,
https://www.acpjournals.org/doi/full/10.7326/M13-1788
134. Fat and cholesterol in the diet of infants and young children: Implications for
growth, development, and long-term health. (1994). The Journal of Pediatrics,
125(5), S69–S77. https://doi.org/10.1016/S0022-3476(06)80739-0,
https://www.sciencedirect.com/science/article/abs/pii/S0022347606807390
135. ‌MCMA, M. C. (2018, December 29). The Shocking Truth about Dietary Fats
and Saturated Fats. https://www.gettingoldandfit.com/dietary-fats/
136. Keneni, Y. G., Bahiru, L. A., & Marchetti, J. M. (2020). Effects of Different
Extraction Solvents on Oil Extracted from Jatropha Seeds and the Potential of
Seed Residues as a Heat Provider. BioEnergy Research.
https://doi.org/10.1007/s12155-020-10217-5,
https://link.springer.com/article/10.1007/s12155-020-10217-5
137. Lobo, V., Patil, A., Phatak, A., & Chandra, N. (2010). Free radicals,
antioxidants and functional foods: Impact on human health. Pharmacognosy
Reviews, 4(8), 118. https://doi.org/10.4103/0973-7847.70902, PMCID:
PMC3249911, PMID: 22228951,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249911/
138. Phaniendra, A., Jestadi, D. B., & Periyasamy, L. (2014). Free Radicals:
Properties, Sources, Targets, and Their Implication in Various Diseases. Indian
Journal of Clinical Biochemistry, 30(1), 11–26.
https://doi.org/10.1007/s12291-014-0446-0, PMCID: PMC4310837, PMID:
25646037, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310837/
139. Jira, W., Spiteller, G., Carson, W., & Schramm, A. (1998). Strong increase in
hydroxy fatty acids derived from linoleic acid in human low density lipoproteins
of atherosclerotic patients. Chemistry and Physics of Lipids, 91(1), 1–11.
https://doi.org/10.1016/s0009-3084(97)00095-9, PMID: 9488997,
https://www.ncbi.nlm.nih.gov/pubmed/9488997?dopt=Abstract
140. Omega-6 fatty acids Information | Mount Sinai - New York. (n.d.). Mount Sinai
Health System.
https://www.mountsinai.org/health-library/supplement/omega-6-fatty-acids
141. ‌Wang, L., Gill, R., Pedersen, T. L., Higgins, L. J., Newman, J. W., & Rutledge, J.
C. (2008). Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized
FFAs that induce endothelial cell inflammation. Journal of Lipid Research, 50(2),
204–213. https://doi.org/10.1194/jlr.m700505-jlr200,
https://www.jlr.org/content/50/2/204?ijkey=12c01c7e3097d64cd27b815eebd2
0500c613f2e7&keytype2=tf_ipsecsh
142. Anil Kumar, Satya Narayan Naik, Ghee : Its Properties, Importance and

291
Health Benefits, Dec. 2018,
https://www.researchgate.net/profile/Anil-Kumar-233/publication/339499398_
Ghee_Its_Properties_Importance_and_Health_Benefits/links/5e562e67299bf1b
db83b26d3/Ghee-Its-Properties-Importance-and-Health-Benefits.pdf
143. Eiselein, L., Wilson, D. W., Lamé, M. W., & Rutledge, J. C. (2007). Lipolysis
products from triglyceride-rich lipoproteins increase endothelial permeability,
perturb zonula occludens-1 and F-actin, and induce apoptosis. American Journal
of Physiology-Heart and Circulatory Physiology, 292(6), H2745–H2753.
https://doi.org/10.1152/ajpheart.00686.2006, PMID: 17259442,
https://www.ncbi.nlm.nih.gov/pubmed/17259442?dopt=Abstract
144. Europe PMC. (n.d.). Europepmc.org, PMID: 8466938
https://europepmc.org/article/med/14203263,
https://www.ncbi.nlm.nih.gov/pubmed/8466938?dopt=Abstract‌
145. Krauss, R. M., Eckel, R. H., Howard, B., Appel, L. J., Daniels, S. R.,
Deckelbaum, R. J., Erdman, J. W., Kris-Etherton, P., Goldberg, I. J., Kotchen, T. A.,
Lichtenstein, A. H., Mitch, W. E., Mullis, R., Robinson, K., Wylie-Rosett, J., St. Jeor,
S., Suttie, J., Tribble, D. L., & Bazzarre, T. L. (2000). AHA Dietary Guidelines.
Circulation, 102(18), 2284–2299. https://doi.org/10.1161/01.cir.102.18.2284,
https://www.ahajournals.org/doi/full/10.1161/01.cir.102.18.2284
146. Blesso, C. N., Andersen, C. J., Barona, J., Volek, J. S., & Fernandez, M. L.
(2013). Whole egg consumption improves lipoprotein profiles and insulin
sensitivity to a greater extent than yolk-free egg substitute in individuals with
metabolic syndrome. Metabolism, 62(3), 400–410.
https://doi.org/10.1016/j.metabol.2012.08.014, PMID: 23021013,
https://www.ncbi.nlm.nih.gov/pubmed/23021013
147. Schnohr, P., Thomsen, O. O., Riis Hansen, P., Boberg-Ans, G., Lawaetz, H., &
Weeke, T. (1994). Egg consumption and high-density-lipoprotein cholesterol.
Journal of Internal Medicine, 235(3), 249–251.
https://doi.org/10.1111/j.1365-2796.1994.tb01068.x,
https://www.ncbi.nlm.nih.gov/pubmed/8120521
148. Mutungi, G., Ratliff, J., Puglisi, M., Torres-Gonzalez, M., Vaishnav, U., Leite, J.
O., Quann, E., Volek, J. S., & Fernandez, M. L. (2008). Dietary cholesterol from
eggs increases plasma HDL cholesterol in overweight men consuming a
carbohydrate-restricted diet. The Journal of Nutrition, 138(2), 272–276.
https://doi.org/10.1093/jn/138.2.272, PMID: 18203890,
https://www.ncbi.nlm.nih.gov/pubmed/18203890
149. Hu, F. B. (1999). A Prospective Study of Egg Consumption and Risk of
Cardiovascular Disease in Men and Women. JAMA, 281(15), 1387.

292
https://doi.org/10.1001/jama.281.15.1387,
https://www.ncbi.nlm.nih.gov/pubmed/10217054
150. Abdel-Aal, E.-S., Akhtar, H., Zaheer, K., & Ali, R. (2013). Dietary Sources of
Lutein and Zeaxanthin Carotenoids and Their Role in Eye Health. Nutrients, 5(4),
1169–1185. https://doi.org/10.3390/nu5041169, PMCID: PMC3705341, PMID:
23571649, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705341/
151. Roberts, J. E., & Dennison, J. (2015). The Photobiology of Lutein and
Zeaxanthin in the Eye. Journal of Ophthalmology, 2015, 1–8.
https://doi.org/10.1155/2015/687173, PMCID: PMC4698938, PMID: 26798505,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698938/
152. Gina Kolata, Study Show Why It’s Hard To Keep Weight Off, Oct 26, 2011,
https://www.nytimes.com/2011/10/27/health/biological-changes-thwart-weight
-loss-e fforts-study-finds.html
153. Dagfinn Aune, Teresa Norat, Pål Romundstad, Lars J Vatten, Whole grain
and refined grain consumption and the risk of type 2 diabetes: a systematic
review and dose-response meta-analysis of cohort studies, PMID: 24158434
DOI: 10.1007/s10654-013-9852-5, https://pubmed.ncbi.nlm.nih.gov/24158434/
154. Luger, M., Lafontan, M., Bes-Rastrollo, M., Winzer, E., Yumuk, V., &
Farpour-Lambert, N. (2017). Sugar-Sweetened Beverages and Weight Gain in
Children and Adults: A Systematic Review from 2013 to 2015 and a
Comparison with Previous Studies. Obesity Facts, 10(6), 674–693.
https://doi.org/10.1159/000484566, PMCID: PMC5836186, PMID: 29237159,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836186/
155. Bleich, S. N., & Vercammen, K. A. (2018). The negative impact of
sugar-sweetened beverages on children’s health: an update of the literature.
BMC Obesity, 5(1), PMCID: PMC5819237, PMID: 29484192,
https://doi.org/10.1186/s40608-017-0178-9,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819237/
156. Malik, V. S., Popkin, B. M., Bray, G. A., Després, J.-P., & Hu, F. B. (2010).
Sugar-Sweetened Beverages, Obesity, Type 2 Diabetes Mellitus, and
Cardiovascular Disease Risk. Circulation, 121(11), 1356–1364.
https://doi.org/10.1161/circulationaha.109.876185, PMCID: PMC2862465,
NIHMSID: NIHMS189965, PMID: 20308626,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862465/
157. Xi, B., Li, S., Liu, Z., Tian, H., Yin, X., Huai, P., Tang, W., Zhou, D., & Steffen, L.
M. (2014). Intake of Fruit Juice and Incidence of Type 2 Diabetes: A Systematic
Review and Meta-Analysis. PLoS ONE, 9(3), e93471,
https://doi.org/10.1371/journal.pone.0093471, PMCID: PMC3969361, PMID:

293
24682091, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969361/
158. Should you get your nutrients from food or from supplements?, Harvard
Health Letter, Published: May, 2015,
https://www.health.harvard.edu/staying-healthy/should-you-get-your-nutrients-
fro m-food-or-from-supplements
159. How high fructose intake may trigger fatty liver disease. (2020, September
14). National Institutes of Health (NIH).
https://www.nih.gov/news-events/nih-research-matters/how-high-fructose-inta
ke-may-trigger-fatty-liver-disease
160. Kotronen, A., & Yki-Järvinen, H. (2008). Fatty Liver. Arteriosclerosis,
Thrombosis, and Vascular Biology, 28(1), 27–38.
https://doi.org/10.1161/atvbaha.107.147538, PMID: 17690317,
https://pubmed.ncbi.nlm.nih.gov/17690317/
161. Erlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P., Mattila,
P., & Jula, A. (2008). Favorable effects of berry consumption on platelet function,
blood pressure, and HDL cholesterol. The American Journal of Clinical Nutrition,
87(2), 323–331. https://doi.org/10.1093/ajcn/87.2.323, ,
https://pubmed.ncbi.nlm.nih.gov/18258621/X
162. Sesso, H. D., Gaziano, J. M., Jenkins, D. J. A., & Buring, J. E. (2007). Strawberry
intake, lipids, C-reactive protein, and the risk of cardiovascular disease in
women. Journal of the American College of Nutrition, 26(4), 303–310.
https://doi.org/10.1080/07315724.2007.10719615,
https://pubmed.ncbi.nlm.nih.gov/17906180/
163. Basu, A., Wilkinson, M., Penugonda, K., Simmons, B., Betts, N. M., & Lyons, T.
J. (2009). Freeze-dried strawberry powder improves lipid profile and lipid
peroxidation in women with metabolic syndrome: baseline and post intervention
effects. Nutrition Journal, 8(1). https://doi.org/10.1186/1475-2891-8-43,
https://pubmed.ncbi.nlm.nih.gov/19785767/
164. McAnulty, S. R., McAnulty, L. S., Morrow, J. D., Khardouni, D., Shooter, L.,
Monk, J., Gross, S., & Brown, V. (2005). Effect of daily fruit ingestion on
angiotensin converting enzyme activity, blood pressure, and oxidative stress in
chronic smokers. Free Radical Research, 39(11), 1241–1248.
https://doi.org/10.1080/10715760500306836,
‌https://pubmed.ncbi.nlm.nih.gov/16298751/
165. Cassidy, A., Mukamal, K. J., Liu, L., Franz, M., Eliassen, A. H., & Rimm, E. B.
(2013). High Anthocyanin Intake Is Associated With a Reduced Risk of
Myocardial Infarction in Young and Middle-Aged Women. Circulation, 127(2),

294
188–196. https://doi.org/10.1161/circulationaha.112.122408,
‌https://www.ahajournals.org/doi/full/10.1161/circulationaha.112.122408
166. Enjoy the Health Benefits of Berries - American Institute for Cancer Research
%. (2020, July 1). American Institute for Cancer Research.
https://www.aicr.org/resources/blog/enjoy-the-health-benefits-of-berries/
167. Olas, B. (2018). Berry Phenolic Antioxidants – Implications for Human
Health? Frontiers in Pharmacology, 9. https://doi.org/10.3389/fphar.2018.00078,
‌https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890122/
168. Lee, S. G., Vance, T. M., Nam, T.-G., Kim, D.-O., Koo, S. I., & Chun, O. K. (2015).
Contribution of Anthocyanin Composition to Total Antioxidant Capacity of
Berries. Plant Foods for Human Nutrition (Dordrecht, Netherlands), 70(4),
427–432. https://doi.org/10.1007/s11130-015-0514-5,
‌https://pubmed.ncbi.nlm.nih.gov/26515081/
169. Seeram, N. P. (2008). Berry Fruits for Cancer Prevention: Current Status and
Future Prospects. Journal of Agricultural and Food Chemistry, 56(3), 630–635.
https://doi.org/10.1021/jf072504n, https://pubmed.ncbi.nlm.nih.gov/18211019/
170. Calvano, A., Izuora, K., Oh, E. C., Ebersole, J. L., Lyons, T. J., & Basu, A. (2019).
Dietary berries, insulin resistance and type 2 diabetes: an overview of human
feeding trials. Food & Function, 10(10), 6227–6243.
https://doi.org/10.1039/c9fo01426h,
‌https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202899/
171. Mcdougall, G. J., & Stewart, D. (2005). The inhibitory effects of berry
polyphenols on digestive enzymes. BioFactors, 23(4), 189–195.
https://doi.org/10.1002/biof.5520230403,
‌https://pubmed.ncbi.nlm.nih.gov/16498205/
172. Essa, M., Al-Adawi, S., Memon, M., Manivasagam, T., Akbar, M., & Subash, S.
(2014). Neuroprotective effects of berry fruits on neurodegenerative diseases.
Neural Regeneration Research, 9(16), 1557.
https://doi.org/10.4103/1673-5374.139483,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192974/
173. Eating berries may lower risk of Parkinson’s. (n.d.). ScienceDaily. Retrieved
April 13, 2022, from
https://www.sciencedaily.com/releases/2011/02/110213162726.htm ‌
174. FoodData Central. (2019). Usda.gov.
‌https://fdc.nal.usda.gov/fdc-app.html#/food-details/171705/nutrients
175. An avocado a day keeps your gut microbes happy, study shows. (n.d.).
ScienceDaily.
https://www.sciencedaily.com/releases/2020/12/201215175758.htm

295
176. Dreher, M. L., & Davenport, A. J. (2013). Hass Avocado Composition and
Potential Health Effects. Critical Reviews in Food Science and Nutrition, 53(7),
738–750. https://doi.org/10.1080/10408398.2011.556759,
‌https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664913/
177. Abdel-Aal, E.-S., Akhtar, H., Zaheer, K., & Ali, R. (2013). Dietary Sources of
Lutein and Zeaxanthin Carotenoids and Their Role in Eye Health. Nutrients, 5(4),
1169–1185. https://doi.org/10.3390/nu5041169,
‌https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705341/
178. Avocado Consumption Increases Macular Pigment Density in Older Adults: A
Randomized, Controlled Trial. (2017). Nutrients, 9(9), 919.
https://doi.org/10.3390/nu9090919,
‌https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622679/
179. Schweiggert, R. M., Kopec, R. E., Villalobos-Gutierrez, M. G., Högel, J.,
Quesada, S., Esquivel, P., Schwartz, S. J., & Carle, R. (2013). Carotenoids are
more bioavailable from papaya than from tomato and carrot in humans: a
randomised cross-over study. British Journal of Nutrition, 111(3), 490–498.
https://doi.org/10.1017/s0007114513002596,
‌https://pubmed.ncbi.nlm.nih.gov/23931131/
180. Kong, Y. R., Jong, Y. X., Balakrishnan, M., Bok, Z. K., Weng, J. K. K., Tay, K. C.,
Goh, B. H., Ong, Y. S., Chan, K. G., Lee, L. H., & Khaw, K. Y. (2021). Beneficial
Role of Carica papaya Extracts and Phytochemicals on Oxidative Stress and
Related Diseases: A Mini Review. Biology, 10(4), 287.
https://doi.org/10.3390/biology10040287,
‌https://www.mdpi.com/2079-7737/10/4/287
181. Milind, P. (2011). BASKETFUL BENEFITS OF PAPAYA. IRJP, 2(7), 6–12.
http://www.irjponline.com/admin/php/uploads/vol-2_issue-7/2.pdf ‌
182. Papaya fruit: Health benefits, uses, and risks. (n.d.).
Www.medicalnewstoday.com.
https://www.medicalnewstoday.com/articles/275517
183. Muss, C., Mosgoeller, W., & Endler, T. (2013). Papaya preparation (Caricol®)
in digestive disorders. Neuro Endocrinology Letters, 34(1), 38–46.
https://pubmed.ncbi.nlm.nih.gov/23524622/
184. Weaver, C. M. (2013). Potassium and Health. Advances in Nutrition, 4(3),
368S377S. https://doi.org/10.3945/an.112.003533 ‌,
https://academic.oup.com/advances/article/4/3/368S/4591617
185. Schroder, K. E. E. (2010). Effects of fruit consumption on body mass index
and weight loss in a sample of overweight and obese dieters enrolled in a
weight-loss intervention trial. Nutrition, 26(7-8), 727–734.

296
https://doi.org/10.1016/j.nut.2009.08.009, ‌
https://pubmed.ncbi.nlm.nih.gov/20022464/
186. Conceição de Oliveira, M., Sichieri, R., & Sanchez Moura, A. (2003). Weight
Loss Associated With a Daily Intake of Three Apples or Three Pears Among
Overweight Women. Nutrition, 19(3), 253–256.
https://doi.org/10.1016/s0899-9007(02)00850-x,
‌https://pubmed.ncbi.nlm.nih.gov/12620529/
187. Boyer, J., & Liu, R. H. (2004). Apple phytochemicals and their health benefits.
Nutrition Journal, 3(1). https://doi.org/10.1186/1475-2891-3-5,
‌https://www.ncbi.nlm.nih.gov/pmc/articles/PMC442131/
188. Fabiani, R., Minelli, L., & Rosignoli, P. (2016). Apple intake and cancer risk: a
systematic review and meta-analysis of observational studies. Public Health
Nutrition, 19(14), 2603–2617. https://doi.org/10.1017/s136898001600032x,
‌https://pubmed.ncbi.nlm.nih.gov/27000627/
189. Bondonno, N. P., Bondonno, C. P., Ward, N. C., Hodgson, J. M., & Croft, K. D.
(2017). The cardiovascular health benefits of apples: Whole fruit vs. isolated
compounds. Trends in Food Science & Technology, 69, 243–256.
https://doi.org/10.1016/j.tifs.2017.04.012,
‌https://eurofir.eu/bacchus/wp-content/uploads/sites/5/2017/10/TIFTS-Nicola-P.-
Bondonno-Catherine-P.-Bondonno-Natalie-C.-Ward-Jonathan-M.-Hodgson-Kev
in-D.-Croft.pdf
190. Chai, S. C., Hooshmand, S., Saadat, R. L., Payton, M. E., Brummel-Smith, K., &
Arjmandi, B. H. (2012). Daily Apple versus Dried Plum: Impact on
Cardiovascular Disease Risk Factors in Postmenopausal Women. Journal of the
Academy of Nutrition and Dietetics, 112(8), 1158–1168.
https://doi.org/10.1016/j.jand.2012.05.005,
https://www.sciencedirect.com/science/article/abs/pii/S2212267212006259
191. Muraki, I., Imamura, F., Manson, J. E., Hu, F. B., Willett, W. C., van Dam, R. M.,
& Sun, Q. (2013). Fruit consumption and risk of type 2 diabetes: results from
three prospective longitudinal cohort studies. BMJ (Clinical Research Ed.), 347,
f5001. https://doi.org/10.1136/bmj.f5001,
‌https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978819/
192. Hyson, D. A. (2011). A Comprehensive Review of Apples and Apple
Components and Their Relationship to Human Health. Advances in Nutrition,
2(5), 408–420. https://doi.org/10.3945/an.111.000513,
‌https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183591/
193. Xu, D., Hu, M.-J., Wang, Y.-Q., & Cui, Y.-L. (2019). Antioxidant Activities of
Quercetin and Its Complexes for Medicinal Application. Molecules, 24(6), 1123.

297
https://doi.org/10.3390/molecules24061123,
‌https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470739/
194. Lauricella, M., Emanuele, S., Calvaruso, G., Giuliano, M., & D’Anneo, A.
(2017). Multifaceted Health Benefits of Mangifera indica L. (Mango): The
Inestimable Value of Orchards Recently Planted in Sicilian Rural Areas.
Nutrients, 9(5), 525. https://doi.org/10.3390/nu9050525,
‌https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452255/
195. Borlinghaus, J., Albrecht, F., Gruhlke, M., Nwachukwu, I., & Slusarenko, A.
(2014). Allicin: Chemistry and Biological Properties. Molecules, 19(8),
12591–12618. https://doi.org/10.3390/molecules190812591,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271412/
196. Shin, J.-H., Ryu, J. H., Kang, M. J., Hwang, C. R., Han, J., & Kang, D. (2013).
Short-term heating reduces the anti-inflammatory effects of fresh raw garlic
extracts on the LPS-induced production of NO and pro-inflammatory cytokines
by downregulating allicin activity in RAW 264.7 macrophages. Food and
Chemical Toxicology, 58, 545–551. https://doi.org/10.1016/j.fct.2013.04.002,
‌https://pubmed.ncbi.nlm.nih.gov/23583806/
197. Mp, N., Ca, R., Ce, M., Ra, C., Jm, S., & Ss, P. (2012, June 1). Supplementation
With Aged Garlic Extract Improves Both NK and γδ-T Cell Function and
Reduces the Severity of Cold and Flu Symptoms: A Randomized, Double-Blind,
Placebo-Controlled Nutrition Intervention. Clinical Nutrition (Edinburgh,
Scotland)., https://pubmed.ncbi.nlm.nih.gov/22280901/
198. Josling, P. (2001). Preventing the common cold with a garlic supplement: A
double-blind, placebo-controlled survey. Advances in Therapy, 18(4), 189–193.
https://doi.org/10.1007/bf02850113,
‌https://www.ncbi.nlm.nih.gov/pubmed/11697022
199. Nantz, M. P., Rowe, C. A., Muller, C. E., Creasy, R. A., Stanilka, J. M., &
Percival, S. S. (2012). Supplementation with aged garlic extract improves both
NK and γδ-T cell function and reduces the severity of cold and flu symptoms: a
randomized, double-blind, placebo-controlled nutrition intervention. Clinical
Nutrition (Edinburgh, Scotland), 31(3), 337–344.
https://doi.org/10.1016/j.clnu.2011.11.019,
https://www.ncbi.nlm.nih.gov/pubmed/22280901
200. Dhawan, V., & Jain, S. (2005). Garlic supplementation prevents oxidative
DNA damage in essential hypertension. Molecular and Cellular Biochemistry,
275(1-2), 85–94. https://doi.org/10.1007/s11010-005-0824-2,
https://www.ncbi.nlm.nih.gov/pubmed/16335787

298
201. Silagy, C., & Neil, A. (1994). Garlic as a lipid lowering agent--a
meta-analysis. Journal of the Royal College of Physicians of London, 28(1),
39–45. https://www.ncbi.nlm.nih.gov/pubmed/8169881
202. Borek, C. (2006). Garlic Reduces Dementia and Heart-Disease Risk. The
Journal of Nutrition, 136(3), 810S812S. https://doi.org/10.1093/jn/136.3.810s,
https://www.ncbi.nlm.nih.gov/pubmed/16484570
203. Zhao Xin-Xin, Lin Fang-Jun, Li Hang, Li Hua-Bin, Wu Ding-Tao, Geng Fang,
Ma Wei, Wang Yu, Miao Bao-He, Gan Ren-You, Recent Advances in Bioactive
Compounds, Health Functions, and Safety Concerns of Onion (Allium cepa L.),
Frontiers in Nutrition, VOLUME=8, 2021,
https://doi.org/10.3389/fnut.2021.669805,
https://www.frontiersin.org/article/10.3389/fnut.2021.669805
204. Marrelli, M., Amodeo, V., Statti, G., & Conforti, F. (2018). Biological Properties
and Bioactive Components of Allium cepa L.: Focus on Potential Benefits in the
Treatment of Obesity and Related Comorbidities. Molecules, 24(1), 119.
https://doi.org/10.3390/molecules24010119,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337254/
205. Wang, S., Zhang, C., Yang, G., & Yang, Y. (2014). Biological properties of
6-gingerol: a brief review. Natural Product Communications, 9(7), 1027–1030.
https://pubmed.ncbi.nlm.nih.gov/25230520/
206. Viljoen, E., Visser, J., Koen, N., & Musekiwa, A. (2014). A systematic review
and meta-analysis of the effect and safety of ginger in the treatment of
pregnancy-associated nausea and vomiting. Nutrition Journal, 13(1).
https://doi.org/10.1186/1475-2891-13-20,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995184/
207. Anh, N. H., Kim, S. J., Long, N. P., Min, J. E., Yoon, Y. C., Lee, E. G., Kim, M., Kim,
T. J., Yang, Y. Y., Son, E. Y., Yoon, S. J., Diem, N. C., Kim, H. M., & Kwon, S. W.
(2020). Ginger on Human Health: A Comprehensive Systematic Review of 109
Randomized Controlled Trials. Nutrients, 12(1), 157.
https://doi.org/10.3390/nu12010157,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019938/
208. Wattanathorn, J., Jittiwat, J., Tongun, T., Muchimapura, S., & Ingkaninan, K.
(2011). Zingiber officinale Mitigates Brain Damage and Improves Memory
Impairment in Focal Cerebral Ischemic Rat. Evidence-Based Complementary and
Alternative Medicine : ECAM, 2011, 429505.
https://doi.org/10.1155/2011/429505,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010628/

299
209. Poltronieri, J., Becceneri, A. B., Fuzer, A. M., Filho, J. C. C., Martin, A. C. B. M.,
Vieira, P. C., Pouliot, N., & Cominetti, M. R. (2014). [6]-gingerol as a cancer
chemopreventive agent: a review of its activity on different steps of the
metastatic process. Mini Reviews in Medicinal Chemistry, 14(4), 313–321.
https://doi.org/10.2174/1389557514666140219095510,
https://pubmed.ncbi.nlm.nih.gov/24552266/
210. Bazzano, L. A., Serdula, M. K., & Liu, S. (2003). Dietary intake of fruits and
vegetables and risk of cardiovascular disease. Current Atherosclerosis Reports,
5(6), 492–499. https://doi.org/10.1007/s11883-003-0040-z,
‌https://pubmed.ncbi.nlm.nih.gov/14525683/
211. Zhang, X., Shu, X.-O., Xiang, Y.-B., Yang, G., Li, H., Gao, J., Cai, H., Gao, Y.-T., &
Zheng, W. (2011). Cruciferous vegetable consumption is associated with a
reduced risk of total and cardiovascular disease mortality. The American Journal
of Clinical Nutrition, 94(1), 240–246. https://doi.org/10.3945/ajcn.110.009340,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127519/
212. Zhao, J., & Zhao, L. (2013). Cruciferous Vegetables Intake Is Associated with
Lower Risk of Renal Cell Carcinoma: Evidence from a Meta-Analysis of
Observational Studies. PLoS ONE, 8(10), e75732.
https://doi.org/10.1371/journal.pone.0075732,
https://pubmed.ncbi.nlm.nih.gov/24204579/
213. Liu, B., Mao, Q., Cao, M., & Xie, L. (2011). Cruciferous vegetables intake and
risk of prostate cancer: A meta-analysis. International Journal of Urology, 19(2),
134–141. https://doi.org/10.1111/j.1442-2042.2011.02906.x,
https://pubmed.ncbi.nlm.nih.gov/22121852/
214. Hu, J., Hu, Y., Hu, Y., & Zheng, S. (2015). Intake of cruciferous vegetables is
associated with reduced risk of ovarian cancer: a meta-analysis. Asia Pacific
Journal of Clinical Nutrition, 24(1), 101–109.
https://doi.org/10.6133/apjcn.2015.24.1.22,
https://pubmed.ncbi.nlm.nih.gov/25740748/
215. Jiang, Y., Wu, S.-H., Shu, X.-O., Xiang, Y.-B., Ji, B.-T., Milne, G. L., Cai, Q.,
Zhang, X., Gao, Y.-T., Zheng, W., & Yang, G. (2014). Cruciferous Vegetable Intake
Is Inversely Correlated with Circulating Levels of Proinflammatory Markers in
Women. Journal of the Academy of Nutrition and Dietetics, 114(5), 700-708.e2.
https://doi.org/10.1016/j.jand.2013.12.019,
https://pubmed.ncbi.nlm.nih.gov/24630682/
216. Santín-Márquez, R., Alarcón-Aguilar, A., López-Diazguerrero, N. E.,
Chondrogianni, N., & Königsberg, M. (2019). Sulforaphane - role in aging and
neurodegeneration. GeroScience, 41(5), 655–670.

300
https://doi.org/10.1007/s11357-019-00061-7,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885086/
217. Porrini, M., Riso, P., & Oriani, G. (2002). Spinach and tomato consumption
increases lymphocyte DNA resistance to oxidative stress but this is not related
to cell carotenoid concentrations. European Journal of Nutrition, 41(3), 95–100.
https://doi.org/10.1007/s003940200014,
https://pubmed.ncbi.nlm.nih.gov/12111045/
218. Moser, B., Szekeres, T., Bieglmayer, C., Wagner, K.-H., Mišík, M., Kundi, M.,
Zakerska, O., Nersesyan, A., Kager, N., Zahrl, J., Hoelzl, C., Ehrlich, V., &
Knasmueller, S. (2011). Impact of spinach consumption on DNA stability in
peripheral lymphocytes and on biochemical blood parameters: results of a
human intervention trial. European Journal of Nutrition, 50(7), 587–594.
https://doi.org/10.1007/s00394-011-0167-6,
https://pubmed.ncbi.nlm.nih.gov/21384253/
219. Longnecker, M. P., Newcomb, P. A., Mittendorf, R., Greenberg, E. R., & Willett,
W. C. (1997). Intake of carrots, spinach, and supplements containing vitamin A
in relation to risk of breast cancer. Cancer Epidemiology, Biomarkers &
Prevention: A Publication of the American Association for Cancer Research,
Cosponsored by the American Society of Preventive Oncology, 6(11), 887–892,
https://pubmed.ncbi.nlm.nih.gov/9367061/
220. Roberts, R. L., Green, J., & Lewis, B. (2009). Lutein and zeaxanthin in eye and
skin health. Clinics in Dermatology, 27(2), 195–201.
https://doi.org/10.1016/j.clindermatol.2008.01.011,
https://pubmed.ncbi.nlm.nih.gov/19168000/
221. Seddon, J. M., Ajani, U. A., Sperduto, R. D., Hiller, R., Blair, N., Burton, T. C.,
Farber, M. D., Gragoudas, E. S., Haller, J., & Miller, D. T. (1994). Dietary
carotenoids, vitamins A, C, and E, and advanced age-related macular
degeneration. Eye Disease Case-Control Study Group. JAMA, 272(18),
1413–1420. https://pubmed.ncbi.nlm.nih.gov/7933422/
222. Jovanovski, E., Bosco, L., Khan, K., Au-Yeung, F., Ho, H., Zurbau, A., Jenkins, A.
L., & Vuksan, V. (2015). Effect of Spinach, a High Dietary Nitrate Source, on
Arterial Stiffness and Related Hemodynamic Measures: A Randomized,
Controlled Trial in Healthy Adults. Clinical Nutrition Research, 4(3), 160–167.
https://doi.org/10.7762/cnr.2015.4.3.160,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525132/ ‌
223. Yang, Y., Marczak, E. D., Usui, H., Kawamura, Y., & Yoshikawa, M. (2004).
Antihypertensive properties of spinach leaf protein digests. Journal of

301
Agricultural and Food Chemistry, 52(8), 2223–2225.
https://doi.org/10.1021/jf034551v, https://pubmed.ncbi.nlm.nih.gov/15080624/
224. Lorizola, I. M., Furlan, C. P. B., Portovedo, M., Milanski, M., Botelho, P. B.,
Bezerra, R. M. N., Sumere, B. R., Rostagno, M. A., & Capitani, C. D. (2018). Beet
Stalks and Leaves (Beta vulgaris L.) Protect Against High-Fat Diet-Induced
Oxidative Damage in the Liver in Mice. Nutrients, 10(7), 872.
https://doi.org/10.3390/nu10070872m
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073334/
225. (PDF) Beet Greens Benefits. (n.d.). ResearchGate. Retrieved April 14, 2022,
from
https://www.researchgate.net/publication/333808500_Beet_Greens_Benefits
226. Abdel-Aal, E.-S., Akhtar, H., Zaheer, K., & Ali, R. (2013). Dietary Sources of
Lutein and Zeaxanthin Carotenoids and Their Role in Eye Health. Nutrients, 5(4),
1169–1185. https://doi.org/10.3390/nu5041169,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705341/
227. OZSOY-SACAN, O., KARABULUT-BULAN, O., BOLKENT, S., YANARDAG, R.,
& OZGEY, Y. (2004). Effects of Chard (Beta vulgarisL. var cicla) on the Liver of
the Diabetic Rats: A Morphological and Biochemical Study. Bioscience,
Biotechnology, and Biochemistry, 68(8), 1640–1648.
https://doi.org/10.1271/bbb.68.1640,
https://pubmed.ncbi.nlm.nih.gov/15322346/
228. Bolkent, Ş., Yanardağ, R., Tabakoğlu-Oğuz, A., & Özsoy-Saçan, Ö. (2000).
Effects of chard (Beta vulgaris L. var. cicla) extract on pancreatic B cells in
streptozotocin-diabetic rats: a morphological and biochemical study. Journal of
Ethnopharmacology, 73(1-2), 251–259.
https://doi.org/10.1016/s0378-8741(00)00328-7,
https://pubmed.ncbi.nlm.nih.gov/11025163/
229. National Institutes of Health. (2017). Office of Dietary Supplements - Folate.
Nih.gov. https://ods.od.nih.gov/factsheets/Folate-HealthProfessional/
230. SAMAD, NADIRA & Debnath, Trishna & Hasnat, Md.Abul & Pervin, Mehnaz
& Kim, Dahye & JO, JEONG & LIM, SA. (2013). Phenolic Contents, Antioxidant
and Anti‐inflammatory Activities of Asparagus cochinchinensis (Loureiro)
Merrill. Journal of Food Biochemistry. 38. 10.1111/jfbc.12028,
https://www.researchgate.net/publication/240305717_Phenolic_Contents_Anti
oxidant_and_Anti-inflammatory_Activities_of_Asparagus_cochinchinensis_Lour
eiro_Merrill
231. Kim, M. J., Moon, Y., Tou, J. C., Mou, B., & Waterland, N. L. (2016). Nutritional
value, bioactive compounds and health benefits of lettuce (Lactuca sativa L.).

302
Journal of Food Composition and Analysis, 49, 19–34.
https://doi.org/10.1016/j.jfca.2016.03.004,
https://www.sciencedirect.com/science/article/abs/pii/S0889157516300230
232. Araruna, K & Carlos, B. (2010). Anti-inflammatory activities of triterpene
lactones from Lactuca sativa. Phytopharmacology. 1. 1-6,
https://www.researchgate.net/publication/228480415_Anti-inflammatory_activi
ties_of_triterpene_lactones_from_Lactuca_sativa
233. Llorach, R., Tomás-Barberán, F. A., & Ferreres, F. (2004). Lettuce and Chicory
Byproducts as a Source of Antioxidant Phenolic Extracts. Journal of Agricultural
and Food Chemistry, 52(16), 5109–5116. https://doi.org/10.1021/jf040055a,
https://pubmed.ncbi.nlm.nih.gov/15291483/
234. Bar-Sela, G., Cohen, M., Ben-Arye, E., & Epelbaum, R. (2015). The Medical
Use of Wheatgrass: Review of the Gap Between Basic and Clinical Applications.
Mini-Reviews in Medicinal Chemistry, 15(12), 1002–1010.
https://doi.org/10.2174/138955751512150731112836,
https://pubmed.ncbi.nlm.nih.gov/26156538/
235. Sethi, J., Yadav, M., Dahiya, K., Sood, S., Singh, V., & Bhattacharya, S. B.
(2010). Antioxidant effect of Triticum aestivium (wheat grass) in high-fat
diet-induced oxidative stress in rabbits. Methods and Findings in Experimental
and Clinical Pharmacology, 32(4), 233.
https://doi.org/10.1358/mf.2010.32.4.1423889,
https://pubmed.ncbi.nlm.nih.gov/20508870/
236. Jang, J.-H., Kim, C.-Y., Lim, S. H., Yang, C. H., Song, K.-S., Han, H. S., Lee, H.-K.,
& Lee, J. (2010). Neuroprotective effects of Triticum aestivum L. against
beta-amyloid-induced cell death and memory impairments. Phytotherapy
Research: PTR, 24(1), 76–84. https://doi.org/10.1002/ptr.2871,
https://pubmed.ncbi.nlm.nih.gov/19441012/
237. Shakya, G., Randhi, P. K., Pajaniradje, S., Mohankumar, K., & Rajagopalan, R.
(2016). Hypoglycaemic role of wheatgrass and its effect on carbohydrate
metabolic enzymes in type II diabetic rats. Toxicology and Industrial Health,
32(6), 1026–1032. https://doi.org/10.1177/0748233714545202,
https://pubmed.ncbi.nlm.nih.gov/25116122/
238. Farzaei, M. H., Abbasabadi, Z., Ardekani, M. R. S., Rahimi, R., & Farzaei, F.
(2013). Parsley: a review of ethnopharmacology, phytochemistry and biological
activities. Journal of Traditional Chinese Medicine, 33(6), 815–826.
https://doi.org/10.1016/s0254-6272(14)60018-2,
https://pubmed.ncbi.nlm.nih.gov/24660617/

303
239. Yanardağ, R., Bolkent, Ş., Tabakoğlu-Oğuz, A., & Özsoy-Saçan, Ö. (2003).
Effects of Petroselinum crispum Extract on Pancreatic B Cells and Blood Glucose
of Streptozotocin-Induced Diabetic Rats. Biological and Pharmaceutical Bulletin,
26(8), 1206–1210. https://doi.org/10.1248/bpb.26.1206,
https://pubmed.ncbi.nlm.nih.gov/12913280/
240. Abou Khalil, N. S., Abou-Elhamd, A. S., Wasfy, S. I. A., El Mileegy, I. M. H.,
Hamed, M. Y., & Ageely, H. M. (2016). Antidiabetic and Antioxidant Impacts of
Desert Date (Balanites aegyptiaca) and Parsley (Petroselinum sativum) Aqueous
Extracts: Lessons from Experimental Rats. Journal of Diabetes Research, 2016,
1–10. https://doi.org/10.1155/2016/8408326,
https://pubmed.ncbi.nlm.nih.gov/27019854/
241. Paarakh, P., Padmaa, M., & Paarakh. (n.d.). Coriandrum sativum
Linn.--Review. Retrieved April 14, 2022, from
https://pharmacologyonline.silae.it/files/newsletter/2009/vol3/57.Padma.pdf
242. Tang, E. L., Rajarajeswaran, J., Fung, S. Y., & Kanthimathi, M. (2013).
Antioxidant activity of Coriandrum sativum and protection against DNA damage
and cancer cell migration. BMC Complementary and Alternative Medicine, 13(1).
https://doi.org/10.1186/1472-6882-13-347
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028854/
243. Hwang, E., Lee, D.-G., Park, S. H., Oh, M. S., & Kim, S. Y. (2014). Coriander
Leaf Extract Exerts Antioxidant Activity and Protects Against UVB-Induced
Photoaging of Skin by Regulation of Procollagen Type I and MMP-1 Expression.
Journal of Medicinal Food, 17(9), 985–995.
https://doi.org/10.1089/jmf.2013.2999,
https://www.liebertpub.com/doi/abs/10.1089/jmf.2013.2999
244. Wesam Kooti, Ghasemiboroon, M., Majid Asadi-Samani, Akaram
Ahangarpoor, Abadi, A., Reza Afrisham, & Dashti, N. (2014). The effects of
hydro-alcoholic extract of celery on lipid profile of rats fed a high fat diet.
Advances in Environmental Biology, 325–331.
https://go.gale.com/ps/anonymous?id=GALE%7CA392176383&sid=googleScho
lar&v=2.1%E2%81%A2=r&linkaccess=fulltext&issn=19950756&p=AONE&sw
=w&authCount=1&isAnonymousEntry=true
245. Moghadam, M. H., Imenshahidi, M., & Mohajeri, S. A. (2013).
Antihypertensive Effect of Celery Seed on Rat Blood Pressure in Chronic
Administration. Journal of Medicinal Food, 16(6), 558–563.
https://doi.org/10.1089/jmf.2012.2664,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684138/

304
246. Kooti, W., & Daraei, N. (2017). A Review of the Antioxidant Activity of Celery
(Apium graveolens L). Journal of Evidence-Based Complementary & Alternative
Medicine, 22(4), 1029–1034. https://doi.org/10.1177/2156587217717415,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871295/
247. Ahmad, Cawood, Iqbal, Ariño, Batool, Tariq, Azam, & Akhtar. (2019).
Phytochemicals in Daucus carota and Their Health Benefits—Review Article.
Foods, 8(9), 424. https://doi.org/10.3390/foods8090424,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770766/
248. Robertson, J., Brydon, W. G., Tadesse, K., Wenham, P., Walls, A., &
Eastwood, M. A. (1979). The effect of raw carrot on serum lipids and colon
function. The American Journal of Clinical Nutrition, 32(9), 1889–1892.
https://doi.org/10.1093/ajcn/32.9.1889,
https://pubmed.ncbi.nlm.nih.gov/474479/
249. Abdel-Aal, E.-S., Akhtar, H., Zaheer, K., & Ali, R. (2013). Dietary Sources of
Lutein and Zeaxanthin Carotenoids and Their Role in Eye Health. Nutrients, 5(4),
1169–1185. https://doi.org/10.3390/nu5041169, ‌
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705341/
250. Validate User. (n.d.). Academic.oup.com. Retrieved April 14, 2022, from
https://academic.oup.com/ajcn/article/80/1/131/4690268
251. Trejo-Solís, C., Pedraza-Chaverrí, J., Torres-Ramos, M., Jiménez-Farfán, D.,
Cruz Salgado, A., Serrano-García, N., Osorio-Rico, L., & Sotelo, J. (2013, July 21).
Multiple Molecular and Cellular Mechanisms of Action of Lycopene in Cancer
Inhibition. Evidence-Based Complementary and Alternative Medicine.
https://www.hindawi.com/journals/ecam/2013/705121/
252. Validate User. (n.d.). Academic.oup.com. Retrieved April 14, 2022, from
https://academic.oup.com/jn/article/137/6/1395/4664768
253. Kapil, V., Khambata, R. S., Robertson, A., Caulfield, M. J., & Ahluwalia, A.
(2015). Dietary Nitrate Provides Sustained Blood Pressure Lowering in
Hypertensive Patients. Hypertension, 65(2), 320–327.
https://doi.org/10.1161/hypertensionaha.114.04675,
https://www.ahajournals.org/doi/full/10.1161/hypertensionaha.114.04675
254. Clifford, T., Howatson, G., West, D., & Stevenson, E. (2015). The Potential
Benefits of Red Beetroot Supplementation in Health and Disease. Nutrients,
7(4), 2801–2822. https://doi.org/10.3390/nu7042801,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425174/
255. Mirmiran, P., Houshialsadat, Z., Gaeini, Z., Bahadoran, Z., & Azizi, F. (2020).
Functional properties of beetroot (Beta vulgaris) in management of
cardio-metabolic diseases. Nutrition & Metabolism, 17(1).

305
https://doi.org/10.1186/s12986-019-0421-0,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947971/
256. (PDF) Nutritional Bioactive Compounds and Health Benefits of Fresh and
Processed Cucumber (Cucumis Sativus L.). (n.d.). ResearchGate.
https://www.researchgate.net/publication/344270982_Nutritional_Bioactive_Co
mpounds_and_Health_Benefits_of_Fresh_and_Processed_Cucumber_Cucumis_
Sativus_L
257. (PDF) Cucumber (Cucumis sativus) - 1.Healthy Vegetables. –Mother Nature
Healing. (n.d.). ResearchGate. Retrieved April 14, 2022, from
https://www.researchgate.net/publication/332221089_Cucumber_Cucumis_sati
vus_-_1Healthy_Vegetables_-Mother_Nature_Healing
258. gatemor, Mark-Maria & Agatemor, & Okwesili, Fred & Nwodo, Okwesili &
Anosike, Chioma. (2015). Anti-inflammatory Activity of Cucumis sativus L.
British Journal of Pharmaceutical Research. 8. 1-8. 10.9734/BJPR/2015/19700,
https://www.researchgate.net/publication/317092042_Anti-inflammatory_Activ
ity_of_Cucumis_sativus_L
259. Chakraborty, Shampa & Rayalu, Sadhana. (2021). Health Beneficial Effects of
Cucumber. 10.5772/intechopen.96053.
https://www.researchgate.net/publication/351580539_Health_Beneficial_Effect
s_of_Cucumber
260. Story, E. N., Kopec, R. E., Schwartz, S. J., & Harris, G. K. (2010). An Update on
the Health Effects of Tomato Lycopene. Annual Review of Food Science and
Technology, 1(1), 189–210.
https://doi.org/10.1146/annurev.food.102308.124120,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850026/
261. Cooperstone, J. L., Tober, K. L., Riedl, K. M., Teegarden, M. D., Cichon, M. J.,
Francis, D. M., Schwartz, S. J., & Oberyszyn, T. M. (2017). Tomatoes protect
against development of UV-induced keratinocyte carcinoma via metabolomic
alterations. Scientific Reports, 7, 5106.
https://doi.org/10.1038/s41598-017-05568-7,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506060/
262. Stahl, W., Heinrich, U., Aust, O., Tronnier, H., & Sies, H. (2006). Lycopene-rich
products and dietary photoprotection. Photochemical & Photobiological
Sciences: Official Journal of the European Photochemistry Association and the
European Society for Photobiology, 5(2), 238–242.
https://doi.org/10.1039/b505312a, https://pubmed.ncbi.nlm.nih.gov/16465309/
263. Raiola, A., Rigano, M. M., Calafiore, R., Frusciante, L., & Barone, A. (2014).
Enhancing the Health-Promoting Effects of Tomato Fruit for Biofortified Food.

306
Mediators of Inflammation, 2014, 1–16. https://doi.org/10.1155/2014/139873,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972926/
264. Yin, J., Liang, Y., Wang, D., Yan, Z., Yin, H., Wu, D., & Su, Q. (2017). Naringenin
induces laxative effects by upregulating the expression levels of c-Kit and SCF,
as well as those of aquaporin 3 in mice with loperamide-induced constipation.
International Journal of Molecular Medicine.
https://doi.org/10.3892/ijmm.2017.3301,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752176/
265. Karppi, J., Laukkanen, J. A., Sivenius, J., Ronkainen, K., & Kurl, S. (2012).
Serum lycopene decreases the risk of stroke in men: a population-based
follow-up study. Neurology, 79(15), 1540–1547.
https://doi.org/10.1212/WNL.0b013e31826e26a6,
https://pubmed.ncbi.nlm.nih.gov/23045517/
266. Willcox, J. K., Catignani, G. L., & Lazarus, S. (2003). Tomatoes and
Cardiovascular Health. Critical Reviews in Food Science and Nutrition, 43(1),
1–18. https://doi.org/10.1080/10408690390826437,
https://pubmed.ncbi.nlm.nih.gov/12587984/
267. Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The Roles of Vitamin C in
Skin Health. Nutrients, 9(8), 866. https://doi.org/10.3390/nu9080866,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579659/
268. Chávez-Mendoza, C., Sanchez, E., Muñoz-Marquez, E., Sida-Arreola, J., &
Flores-Cordova, M. (2015). Bioactive Compounds and Antioxidant Activity in
Different Grafted Varieties of Bell Pepper. Antioxidants, 4(2), 427–446.
https://doi.org/10.3390/antiox4020427,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665466/
269. Red Bell Pepper - an overview | ScienceDirect Topics. (n.d.).
Www.sciencedirect.com. Retrieved April 14, 2022, from
https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/red-b
ell-pepper
270. Radulian, G., Rusu, E., Dragomir, A., & Posea, M. (2009). Metabolic effects of
low glycaemic index diets. Nutrition Journal, 8(1).
https://doi.org/10.1186/1475-2891-8-5,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654909/
271. Muhammad Yasir Naeem, & Senay. (2020, January 6). Nutritional Content
and Health Benefits of Eggplant. ResearchGate; Turkish Journal of Agriculture -
Food Science and Technology (TURJAF).
https://www.researchgate.net/publication/338402175_Nutritional_Content_and
_Health_Benefits_of_Eggplant

307
272. Blundell, J. E., & Burley, V. J. (1987). Satiation, satiety and the action of fibre
on food intake. International Journal of Obesity, 11 Suppl 1, 9–25.
https://pubmed.ncbi.nlm.nih.gov/3032831/
273. Kora, A. J. (2020). Nutritional and antioxidant significance of
selenium-enriched mushrooms. Bulletin of the National Research Centre, 44(1).
https://doi.org/10.1186/s42269-020-00289-w,
https://bnrc.springeropen.com/articles/10.1186/s42269-020-00289-w
274. Dong, Z., Xiao, Y., & Wu, H. (2021). Selenium accumulation, speciation, and
its effect on nutritive value of Flammulina velutipes (Golden needle mushroom).
Food Chemistry, 350, 128667. https://doi.org/10.1016/j.foodchem.2020.128667,
https://www.sciencedirect.com/science/article/abs/pii/S0308814620325292?dgc
id=rss_sd_all
275. Cerletti, C., Esposito, S., & Iacoviello, L. (2021). Edible Mushrooms and
Beta-Glucans: Impact on Human Health. Nutrients, 13(7), 2195.
https://doi.org/10.3390/nu13072195,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308413/
276. Chen, J., & Raymond, K. (2008). Beta-glucans in the treatment of diabetes
and associated cardiovascular risks. Vascular Health and Risk Management,
4(6), 1265–1272. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663451/
277. Kabir, Yearul & KIMURA, Shuichi. (1989). Dietary mushrooms reduce blood
pressure in spontaneously hypertensive rats (SHR). Journal of nutritional science
and vitaminology. 35. 91-4. 10.3177/jnsv.35.91.,
https://www.researchgate.net/publication/20416953_Dietary_mushrooms_redu
ce_blood_pressure_in_spontaneously_hypertensive_rats_SHR
278. Mohamed Yahaya, N. F., Rahman, M. A., & Abdullah, N. (2014). Therapeutic
potential of mushrooms in preventing and ameliorating hypertension. Trends in
Food Science & Technology, 39(2), 104–115.
https://doi.org/10.1016/j.tifs.2014.06.002,
https://www.sciencedirect.com/science/article/abs/pii/S0924224414001289
279. Kabir, Y., Yamaguchi, M., & Kimura, S. (1987). Effect of shiitake (Lentinus
edodes) and maitake (Grifola frondosa) mushrooms on blood pressure and
plasma lipids of spontaneously hypertensive rats. Journal of Nutritional Science
and Vitaminology, 33(5), 341–346. https://doi.org/10.3177/jnsv.33.341,
https://pubmed.ncbi.nlm.nih.gov/3443885/
280. Tsai, C.-H., Chen, E. C.-F., Tsay, H.-S., & Huang, C. (2012). Wild bitter gourd
improves metabolic syndrome: A preliminary dietary supplementation trial.
Nutrition Journal, 11, 4. https://doi.org/10.1186/1475-2891-11-4,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311063/

308
281. Kumari, Preeti & R.B.Verma, & Nayik, Gulzar & Solankey, Shashank S.. (2017).
Antioxidant Potential and health benefits of bitter gourd (Momoridica charantia
L.). 05. 1-8.
https://www.researchgate.net/publication/328077765_Antioxidant_Potential_a
nd_health_benefits_of_bitter_gourd_Momoridica_charantia_L
282. El Khoury, D., Cuda, C., Luhovyy, B. L., & Anderson, G. H. (2012). Beta
Glucan: Health Benefits in Obesity and Metabolic Syndrome. Journal of Nutrition
and Metabolism, 2012, 1–28. https://doi.org/10.1155/2012/851362,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236515/
283. Størsrud, S., Hulthén, L. R., & Lenner, R. A. (2003). Beneficial effects of oats
in the gluten-free diet of adults with special reference to nutrient status,
symptoms and subjective experiences. British Journal of Nutrition, 90(1),
101–107. https://doi.org/10.1079/bjn2003872,PMID: 12844381,
https://pubmed.ncbi.nlm.nih.gov/12844381/
284. Whole Grains, Refined Grains, and Dietary Fiber. (2016). Www.heart.org.
https://www.heart.org/en/healthy-living/healthy-eating/eat-smart/nutrition-basic
s/whol e-grains-refined-grains-and-dietary-fiber
285. Angeli, V., Miguel Silva, P., Crispim Massuela, D., Khan, M. W., Hamar, A.,
Khajehei, F., Graeff-Hönninger, S., & Piatti, C. (2020). Quinoa (Chenopodium
quinoa Willd.): An Overview of the Potentials of the “Golden Grain” and
Socio-Economic and Environmental Aspects of Its Cultivation and Marketization.
Foods, 9(2). https://doi.org/10.3390/foods9020216 , PMCID: PMC7074363,
PMID: 32092899, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074363/
286. Wu, G. (2016). Dietary protein intake and human health. Food & Function,
7(3), 1251–1265. https://doi.org/10.1039/c5fo01530h,
‌https://pubmed.ncbi.nlm.nih.gov/26797090/
287. Kreider, R. B., & Campbell, B. (2009). Protein for exercise and recovery. The
Physician and Sportsmedicine, 37(2), 13–21.
https://doi.org/10.3810/psm.2009.06.1705,
https://pubmed.ncbi.nlm.nih.gov/20048505/
288. McNamara, D. J. (2000). Dietary cholesterol and atherosclerosis. Biochimica
et Biophysica Acta, 1529(1-3), 310–320.
https://doi.org/10.1016/s1388-1981(00)00156-6,
https://pubmed.ncbi.nlm.nih.gov/11111098/
289. Blesso, C. N., Andersen, C. J., Barona, J., Volek, J. S., & Fernandez, M. L.
(2013). Whole egg consumption improves lipoprotein profiles and insulin
sensitivity to a greater extent than yolk-free egg substitute in individuals with
metabolic syndrome. Metabolism, 62(3), 400–410.

309
https://doi.org/10.1016/j.metabol.2012.08.014,
https://www.ncbi.nlm.nih.gov/pubmed/23021013
290. Schnohr, P., Thomsen, O. O., Riis Hansen, P., Boberg-Ans, G., Lawaetz, H., &
Weeke, T. (1994). Egg consumption and high-density-lipoprotein cholesterol.
Journal of Internal Medicine, 235(3), 249–251.
https://doi.org/10.1111/j.1365-2796.1994.tb01068.x,
https://www.ncbi.nlm.nih.gov/pubmed/8120521
291. Mutungi, G., Ratliff, J., Puglisi, M., Torres-Gonzalez, M., Vaishnav, U., Leite, J.
O., Quann, E., Volek, J. S., & Fernandez, M. L. (2008). Dietary cholesterol from
eggs increases plasma HDL cholesterol in overweight men consuming a
carbohydrate-restricted diet. The Journal of Nutrition, 138(2), 272–276.
https://doi.org/10.1093/jn/138.2.272,
https://www.ncbi.nlm.nih.gov/pubmed/18203890
292. Jones, P. J. H., Pappu, A. S., Hatcher, L., Li, Z.-C., Illingworth, D. R., & Connor,
W. E. (1996). Dietary Cholesterol Feeding Suppresses Human Cholesterol
Synthesis Measured by Deuterium Incorporation and Urinary Mevalonic Acid
Levels. Arteriosclerosis, Thrombosis, and Vascular Biology, 16(10), 1222–1228.
https://doi.org/10.1161/01.atv.16.10.1222,
https://pubmed.ncbi.nlm.nih.gov/8857917/
293. Shimomura, I., Bashmakov, Y., Shimano, H., Horton, J. D., Goldstein, J. L., &
Brown, M. S. (1997). Cholesterol feeding reduces nuclear forms of sterol
regulatory element binding proteins in hamster liver. Proceedings of the
National Academy of Sciences of the United States of America, 94(23),
12354–12359. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC24942/
294. Réhault-Godbert, S., Guyot, N., & Nys, Y. (2019). The Golden Egg: Nutritional
Value, Bioactivities, and Emerging Benefits for Human Health. Nutrients, 11(3),
684. https://doi.org/10.3390/nu11030684,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470839/
295. Zeisel, S. H., & da Costa, K.-A. (2009). Choline: an essential nutrient for
public health. Nutrition Reviews, 67(11), 615–623.
https://doi.org/10.1111/j.1753-4887.2009.00246.x,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782876/
296. Abdel-Aal, E.-S., Akhtar, H., Zaheer, K., & Ali, R. (2013). Dietary Sources of
Lutein and Zeaxanthin Carotenoids and Their Role in Eye Health. Nutrients, 5(4),
1169–1185. https://doi.org/10.3390/nu5041169,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705341/
297. Buscemi, S., Corleo, D., Di Pace, F., Petroni, M., Satriano, A., & Marchesini, G.
(2018). The Effect of Lutein on Eye and Extra-Eye Health. Nutrients, 10(9),

310
1321. https://doi.org/10.3390/nu10091321,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164534/
298. The Truth about Raw Milk. (n.d.). Dr. Axe. Retrieved April 14, 2022, from
https://draxe.com/raw-milk-benefits/
299. Raw Milk Reality: Is Raw Milk Dangerous? (2012, May 9). Chris Kresser.
https://chriskresser.com/raw-milk-reality-is-raw-milk-dangerous/
300. Amara, A. A., & Shibl, A. (2015). Role of Probiotics in health improvement,
infection control and disease treatment and management. Saudi Pharmaceutical
Journal, 23(2), 107–114. https://doi.org/10.1016/j.jsps.2013.07.001,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421088/
301. Daniel, D. C. O. (2018). Impact of Informal Groups on Organisational
Performance. International Journal of Scientific Research and Management,
6(09), EM–2018-686-694. https://doi.org/10.18535/ijsrm
https://ijsrm.in/index.php/ijsrm/article/view/892
302. Moore, J. B., Horti, A., & Fielding, B. A. (2018). Evaluation of the nutrient
content of yogurts: a comprehensive survey of yogurt products in the major UK
supermarkets. BMJ Open, 8(8), e021387.
https://doi.org/10.1136/bmjopen-2017-021387,
https://bmjopen.bmj.com/content/8/8/e021387
303. Validate User. (n.d.). Academic.oup.com. Retrieved April 14, 2022, from
https://academic.oup.com/ajcn/article/
304. Weaver, C. M. (2013). Potassium and Health. Advances in Nutrition, 4(3),
368S377S. https://doi.org/10.3945/an.112.003533,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650509/
305. 99% of All Animal Products in the U.S. Come From Factory Farms. (2019,
April 25). LIVEKINDLY.
https://www.livekindly.co/99-animal-products-factory-farms
306. Daley, C. A., Abbott, A., Doyle, P. S., Nader, G. A., & Larson, S. (2010). A
review of fatty acid profiles and antioxidant content in grass-fed and grain-fed
beef. Nutrition Journal, 9(1). https://doi.org/10.1186/1475-2891-9-10,
https://nutritionj.biomedcentral.com/articles/10.1186/1475-2891-9-10
307. TED. (2013). How to green the world’s deserts and reverse climate change |
Allan Savory. In YouTube. https://www.youtube.com/watch?v=vpTHi7O66pI
308. Hites, R. A., Foran, J. A., Carpenter, D. O., Hamilton, M. C., Knuth, B. A., &
Schwager, S. J. (2004). Global Assessment of Organic Contaminants in Farmed
Salmon. Science, 303(5655), 226–229.
https://doi.org/10.1126/science.1091447,
https://pubmed.ncbi.nlm.nih.gov/14716013/

311
309. Says, G. C. (n.d.). The Dangers of Eating Farmed Fish | Farmed Fish Bad for
Health. https://gobeyondrelief.com/dangers-eating-farmed-fish/
310. Kris-Etherton, P. M., Harris, W. S., & Appel, L. J. (2002). Fish Consumption,
Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease. Circulation, 106(21),
2747–2757. https://doi.org/10.1161/01.cir.0000038493.65177.94,
https://www.ahajournals.org/doi/10.1161/01.CIR.0000038493.65177.94
311. 5 Reasons Why You Should Avoid Farm-Raised Fish. (2014, May 21). David
Perlmutter M.D.
https://www.drperlmutter.com/5-reasons-avoid-farm-raised-fish/
312. Sharma, H., Zhang, X., & Dwivedi, C. (2010). The effect of ghee (clarified
butter) on serum lipid levels and microsomal lipid peroxidation. AYU (an
International Quarterly Journal of Research in Ayurveda), 31(2), 134.
https://doi.org/10.4103/0974-8520.72361, PMCID: PMC3215354, PMID:
22131700, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215354/
313. Schwingshackl, L., & Hoffmann, G. (2014). Monounsaturated fatty acids,
olive oil and health status: a systematic review and meta-analysis of cohort
studies. Lipids in Health and Disease, 13(1).
https://doi.org/10.1186/1476-511x-13-154,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198773/
314. Schwingshackl, L., Christoph, M., & Hoffmann, G. (2015). Effects of Olive Oil
on Markers of Inflammation and Endothelial Function—A Systematic Review
and Meta-Analysis. Nutrients, 7(9), 7651–7675.
https://doi.org/10.3390/nu7095356 ,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586551/
315. Hohmann, C. D., Cramer, H., Michalsen, A., Kessler, C., Steckhan, N., Choi, K.,
& Dobos, G. (2015). Effects of high phenolic olive oil on cardiovascular risk
factors: A systematic review and meta-analysis. Phytomedicine, 22(6), 631–640.
https://doi.org/10.1016/j.phymed.2015.03.019,
https://pubmed.ncbi.nlm.nih.gov/26055128/
316. Banel, D. K., & Hu, F. B. (2009). Effects of walnut consumption on blood
lipids and other cardiovascular risk factors: a meta-analysis and systematic
review. The American Journal of Clinical Nutrition, 90(1), 56–63.
https://doi.org/10.3945/ajcn.2009.27457,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696995/
317. Yin, T.-P., Cai, L., Chen, Y., Li, Y., Wang, Y.-R., Liu, C.-S., & Ding, Z.-T. (2015).
Tannins and Antioxidant Activities of the Walnut (Juglans regia) Pellicle. Natural
Product Communications, 10(12), 2141–2144.
https://www.ncbi.nlm.nih.gov/pubmed/26882685

312
318. Spaccarotella, K. J., Kris-Etherton, P. M., Stone, W. L., Bagshaw, D. M., Fishell,
V. K., West, S. G., Lawrence, F. R., & Hartman, T. J. (2008). The effect of walnut
intake on factors related to prostate and vascular health in older men. Nutrition
Journal, 7(1). https://doi.org/10.1186/1475-2891-7-13,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2412899/
319. Doerr, A. (2018, February 28). Nut consumption may aid colon cancer
survival. YaleNews.
https://news.yale.edu/2018/02/28/nut-consumption-may-aid-colon-cancer-survi
val
320. Rizvi, S., Raza, S. T., Ahmed, F., Ahmad, A., Abbas, S., & Mahdi, F. (2014). The
role of vitamin e in human health and some diseases. Sultan Qaboos University
Medical Journal, 14(2), e157-65.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997530/
321. Barreca, D., Nabavi, S. M., Sureda, A., Rasekhian, M., Raciti, R., Silva, A. S.,
Annunziata, G., Arnone, A., Tenore, G. C., Süntar, İ., & Mandalari, G. (2020).
Almonds (Prunus Dulcis Mill. D. A. Webb): A Source of Nutrients and
Health-Promoting Compounds. Nutrients, 12(3), 672.
https://doi.org/10.3390/nu12030672,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146189/
322. Arya, S. S., Salve, A. R., & Chauhan, S. (2015). Peanuts as functional food: a
review. Journal of Food Science and Technology, 53(1), 31–41.
https://doi.org/10.1007/s13197-015-2007-9,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711439/table/Tab2/?report=obj
ectonly
323. FoodData Central. (n.d.). Fdc.nal.usda.gov.
https://fdc.nal.usda.gov/fdc-app.html#/food-details/324860/nutrients
324. Marineli, R. da S., Moraes, É. A., Lenquiste, S. A., Godoy, A. T., Eberlin, M. N.,
& Maróstica Jr, M. R. (2014). Chemical characterization and antioxidant potential
of Chilean chia seeds and oil (Salvia hispanica L.). LWT - Food Science and
Technology, 59(2, Part 2), 1304–1310.
https://doi.org/10.1016/j.lwt.2014.04.014,
https://www.sciencedirect.com/science/article/pii/S0023643814002072
325. Pham-Huy, L. A., He, H., & Pham-Huy, C. (2008). Free radicals, antioxidants
in disease and health. International Journal of Biomedical Science : IJBS, 4(2),
89–96. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614697/
326. Vuksan, V., Whitham, D., Sievenpiper, J. L., Jenkins, A. L., Rogovik, A. L.,
Bazinet, R. P., Vidgen, E., & Hanna, A. (2007). Supplementation of Conventional
Therapy With the Novel Grain Salba (Salvia hispanica L.) Improves Major and

313
Emerging Cardiovascular Risk Factors in Type 2 Diabetes: Results of a
randomized controlled trial. Diabetes Care, 30(11), 2804–2810.
https://doi.org/10.2337/dc07-1144,
https://diabetesjournals.org/care/article/30/11/2804/4809/Supplementation-of-
Conventional-Therapy-With-the
327. Flax Nutrition Profile | Flax Council Of Canada. (n.d.). Retrieved April 14,
2022, from
https://flaxcouncil.ca/resources/nutrition/general-nutrition-information/nutrition-
profile/
328. Mani, U. V., Mani, I., Biswas, M., & Kumar, S. N. (2011). An Open-Label Study
on the Effect of Flax Seed Powder (Linum usitatissimum) Supplementation in
the Management of Diabetes Mellitus. Journal of Dietary Supplements, 8(3),
257–265. https://doi.org/10.3109/19390211.2011.593615,
https://pubmed.ncbi.nlm.nih.gov/22432725/
329. Irakli, M., Tsaliki, E., Kalivas, A., Kleisiaris, F., Sarrou, E., & Cook, C. M. (2019).
Effect οf Genotype and Growing Year on the Nutritional, Phytochemical, and
Antioxidant Properties of Industrial Hemp (Cannabis sativa L.) Seeds.
Antioxidants, 8(10), 491. https://doi.org/10.3390/antiox8100491,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826498/
330. Wang, Q., & Xiong, Y. L. (2019). Processing, Nutrition, and Functionality of
Hempseed Protein: A Review. Comprehensive Reviews in Food Science and
Food Safety, 18(4), 936–952. https://doi.org/10.1111/1541-4337.12450,
https://ift.onlinelibrary.wiley.com/doi/full/10.1111/1541-4337.12450
331. FoodData Central. (n.d.). Fdc.nal.usda.gov.
https://fdc.nal.usda.gov/fdc-app.html#/food-details/171917/nutrients
332. Chacko, S. M., Thambi, P. T., Kuttan, R., & Nishigaki, I. (2010). Beneficial
effects of green tea: A literature review. Chinese Medicine, 5(1), 13.
https://doi.org/10.1186/1749-8546-5-13,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855614/
333. Validate User. (n.d.). Academic.oup.com.
https://academic.oup.com/advances/article/11/4/790/5732737?login=false
334. Zhang, M., Holman, C. D. J., Huang, J. ., & Xie, X. (2006). Green tea and the
prevention of breast cancer: a case-control study in Southeast China.
Carcinogenesis, 28(5), 1074–1078. https://doi.org/10.1093/carcin/bgl252,
https://pubmed.ncbi.nlm.nih.gov/17183063/
335. Lambert, J. D., & Yang, C. S. (2003). Mechanisms of Cancer Prevention by Tea
Constituents. The Journal of Nutrition, 133(10), 3262S3267S.

314
https://doi.org/10.1093/jn/133.10.3262s,
‌https://pubmed.ncbi.nlm.nih.gov/14519824/
336. Weisburger, J. H. (2003). Prevention of coronary heart disease and cancer by
tea, a review. Environmental Health and Preventive Medicine, 7(6), 283–288.
https://doi.org/10.1007/bf02908887,
https://pubmed.ncbi.nlm.nih.gov/21432397/
337. Koo, M. W. L., & Cho, C. H. (2004). Pharmacological effects of green tea on
the gastrointestinal system. European Journal of Pharmacology, 500(1-3),
177–185. https://doi.org/10.1016/j.ejphar.2004.07.023,
https://pubmed.ncbi.nlm.nih.gov/15464031/
338. Tea and Cancer Prevention. (2010). National Cancer Institute; Cancer.gov.
https://www.cancer.gov/about-cancer/causes-prevention/risk/diet/tea-fact-sheet
339. Weinreb, O., Mandel, S., Amit, T., & Youdim, M. B. H. (2004). Neurological
mechanisms of green tea polyphenols in Alzheimer’s and Parkinson’s diseases.
The Journal of Nutritional Biochemistry, 15(9), 506–516.
https://doi.org/10.1016/j.jnutbio.2004.05.002,
https://pubmed.ncbi.nlm.nih.gov/15350981/
340. Chacko, S. M., Thambi, P. T., Kuttan, R., & Nishigaki, I. (2010). Beneficial
effects of green tea: A literature review. Chinese Medicine, 5(1), 13.
https://doi.org/10.1186/1749-8546-5-13,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855614/
341. Ohishi, T., Goto, S., Monira, P., Isemura, M., & Nakamura, Y. (2016).
Anti-inflammatory Action of Green Tea. Anti-Inflammatory & Anti-Allergy
Agents in Medicinal Chemistry, 15(2), 74–90.
https://doi.org/10.2174/1871523015666160915154443,
https://pubmed.ncbi.nlm.nih.gov/27634207/
342. Katiyar, S. K., Ahmad, N., & Mukhtar, H. (2000). Green Tea and Skin. Archives
of Dermatology, 136(8), 989–994. https://doi.org/10.1001/archderm.136.8.989,
https://pubmed.ncbi.nlm.nih.gov/10926734/
343. Gheflati, A., Bashiri, R., Ghadiri-Anari, A., Reza, J. Z., Kord, M. T., &
Nadjarzadeh, A. (2019). The effect of apple vinegar consumption on glycemic
indices, blood pressure, oxidative stress, and homocysteine in patients with type
2 diabetes and dyslipidemia: A randomized controlled clinical trial. Clinical
Nutrition ESPEN, 33, 132–138. https://doi.org/10.1016/j.clnesp.2019.06.006,
‌https://pubmed.ncbi.nlm.nih.gov/31451249/
344. Brighenti, F., Castellani, G., Benini, L., Casiraghi, M. C., Leopardi, E., Crovetti,
R., & Testolin, G. (1995). Effect of neutralized and native vinegar on blood
glucose and acetate responses to a mixed meal in healthy subjects. European

315
Journal of Clinical Nutrition, 49(4), 242–247.
https://www.ncbi.nlm.nih.gov/pubmed/7796781,
https://www.ncbi.nlm.nih.gov/pubmed/7796781
345. Johnston, C. S., Kim, C. M., & Buller, A. J. (2003). Vinegar Improves Insulin
Sensitivity to a High-Carbohydrate Meal in Subjects With Insulin Resistance or
Type 2 Diabetes. Diabetes Care, 27(1), 281–282.
https://doi.org/10.2337/diacare.27.1.281,
http://care.diabetesjournals.org/content/27/1/281.long
346. Hadi, A., Pourmasoumi, M., Najafgholizadeh, A., Clark, C. C. T., &
Esmaillzadeh, A. (2021). The effect of apple cider vinegar on lipid profiles and
glycemic parameters: a systematic review and meta-analysis of randomized
clinical trials. BMC Complementary Medicine and Therapies, 21.
https://doi.org/10.1186/s12906-021-03351-w,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243436/
347. Yamashita, H., Fujisawa, K., Ito, E., Idei, S., Kawaguchi, N., Kimoto, M., Hiemori,
M., & Tsuji, H. (2007). Improvement of obesity and glucose tolerance by acetate
in Type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Bioscience,
Biotechnology, and Biochemistry, 71(5), 1236–1243.
https://doi.org/10.1271/bbb.60668,
https://www.ncbi.nlm.nih.gov/pubmed/17485860
348. Gordon, M. H., & Wishart, K. (2010). Effects of chlorogenic acid and bovine
serum albumin on the oxidative stability of low density lipoproteins in vitro.
Journal of Agricultural and Food Chemistry, 58(9), 5828–5833.
https://doi.org/10.1021/jf100106e,
https://www.ncbi.nlm.nih.gov/pubmed/20387813
349. Weiss, D. J., & Anderton, C. R. (2003). Determination of catechins in matcha
green tea by micellar electrokinetic chromatography. Journal of Chromatography
A, 1011(1-2), 173–180. https://doi.org/10.1016/s0021-9673(03)01133-6,
https://pubmed.ncbi.nlm.nih.gov/14518774/
350. Jakubczyk, K., Kochman, J., Kwiatkowska, A., Kałduńska, J., Dec, K., Kawczuga,
D., & Janda, K. (2020). Antioxidant Properties and Nutritional Composition of
Matcha Green Tea. Foods, 9(4). https://doi.org/10.3390/foods9040483,
https://www.mdpi.com/2304-8158/9/4/483/htm
351. Jakubczyk, K., Kochman, J., Kwiatkowska, A., Kałduńska, J., Dec, K., Kawczuga,
D., & Janda, K. (2020). Antioxidant Properties and Nutritional Composition of
Matcha Green Tea. Foods, 9(4). https://doi.org/10.3390/foods9040483,
https://pubmed.ncbi.nlm.nih.gov/32290537/

316
352. Tea and Cancer Prevention. (2010). National Cancer Institute; Cancer.gov.
https://www.cancer.gov/about-cancer/causes-prevention/risk/diet/tea-fact-sheet
353. Mousavi, A., Vafa, M., Neyestani, T., Khamseh, M., & Hoseini, F. (2013). The
effects of green tea consumption on metabolic and anthropometric indices in
patients with Type 2 diabetes. Journal of Research in Medical Sciences : The
Official Journal of Isfahan University of Medical Sciences, 18(12), 1080–1086.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908530/
354. Miyata, Y., ScienMatsuoces, T., Araki, K., Nakamura, Y., Sagara, Y., Ohba, K., &
Sakai, H. (2018). Anticancer Effects of Green Tea and the Underlying Molecular
Mechanisms in Bladder Cancer. Medicines, 5(3), 87.
https://doi.org/10.3390/medicines5030087,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164790/
355. Tian, C., Huang, Q., Yang, L., Légaré, S., Angileri, F., Yang, H., Li, X., Min, X.,
Zhang, C., Xu, C., Yuan, J., Miao, X., He, M., Wu, T., & Zhang, X. (2016). Green tea
consumption is associated with reduced incident CHD and improved
CHD-related biomarkers in the Dongfeng-Tongji cohort. Scientific Reports, 6(1).
https://doi.org/10.1038/srep24353,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829846/
356. Yamabe, N., Kang, K. S., Hur, J. M., & Yokozawa, T. (2009). Matcha, a
Powdered Green Tea, Ameliorates the Progression of Renal and Hepatic
Damage in Type 2 Diabetic OLETF Rats. Journal of Medicinal Food, 12(4),
714–721. https://doi.org/10.1089/jmf.2008.1282,
https://pubmed.ncbi.nlm.nih.gov/19735169/
357. Peng, X., Zhou, R., Wang, B., Yu, X., Yang, X., Liu, K., & Mi, M. (2014). Effect of
green tea consumption on blood pressure: A meta-analysis of 13 randomized
controlled trials. Scientific Reports, 4(1). https://doi.org/10.1038/srep06251,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150247/
358. Yin, X., Yang, J., Li, T., Song, L., Han, T., Yang, M., Liao, H., He, J., & Zhong, X.
(2015). The effect of green tea intake on risk of liver disease: a meta analysis.
International Journal of Clinical and Experimental Medicine, 8(6), 8339–8346.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538013/
359. Askari, G., Pezeshki, A., Safi, S., Feizi, A., & Karami, F. (2016). The effect of
green tea extract supplementation on liver enzymes in patients with
nonalcoholic fatty liver disease. International Journal of Preventive Medicine,
7(1), 28. https://doi.org/10.4103/2008-7802.173051,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763469/
360. Mbikay, M. (2012). Therapeutic Potential of Moringa oleifera Leaves in
Chronic Hyperglycemia and Dyslipidemia: A Review. Frontiers in Pharmacology,

317
3. https://doi.org/10.3389/fphar.2012.00024,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290775/
361. Sulaiman, M. R., Zakaria, Z. A., Bujarimin, A. S., Somchit, M. N., Israf, D. A., &
Moin, S. (2008). Evaluation ofMoringa oleiferaAqueous Extract for
Antinociceptive and Anti-Inflammatory Activities in Animal Models.
Pharmaceutical Biology, 46(12), 838–845.
https://doi.org/10.1080/13880200802366710,
https://www.tandfonline.com/doi/full/10.1080/13880200802366710
362. Mahajan, S. G., & Mehta, A. A. (2010). Immunosuppressive activity of
ethanolic extract of seeds of Moringa oleifera Lam. in experimental immune
inflammation. Journal of Ethnopharmacology, 130(1), 183–186.
https://doi.org/10.1016/j.jep.2010.04.024,
https://pubmed.ncbi.nlm.nih.gov/20435128/
363. Anwar, F., Latif, S., Ashraf, M., & Gilani, A. H. (2006). Moringa oleifera: a food
plant with multiple medicinal uses. Phytotherapy Research, 21(1), 17–25.
https://doi.org/10.1002/ptr.2023,
https://onlinelibrary.wiley.com/doi/abs/10.1002/ptr.2023
364. Nova, E., Redondo-Useros, N., Martínez-García, R. M., Gómez-Martínez, S.,
Díaz-Prieto, L. E., & Marcos, A. (2020). Potential of Moringa oleifera to Improve
Glucose Control for the Prevention of Diabetes and Related Metabolic
Alterations: A Systematic Review of Animal and Human Studies. Nutrients,
12(7), 2050. https://doi.org/10.3390/nu12072050,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400864/
365. Owens, F. S., Dada, O., Cyrus, J. W., Adedoyin, O. O., & Adunlin, G. (2020).
The effects of Moringa oleifera on blood glucose levels: A scoping review of the
literature. Complementary Therapies in Medicine, 50, 102362.
https://doi.org/10.1016/j.ctim.2020.102362,
https://www.sciencedirect.com/science/article/abs/pii/S0965229919316991#:~:t
ext=Out%20of%20seven%20human%20studies,in%20animal%20blood
366. (PDF) Health Benefits of Moringa oleifera. (n.d.). ResearchGate.
https://www.researchgate.net/publication/267932962_Health_Benefits_of_Mori
nga_oleifera
367. Johnkennedy, N., Joy, D.-N., Ndubueze, E. H., Melvina, N., Richard, E., & Vitus,
O. (2013, July 1). Antioxidant and Cardioprotective Effect of Coconut Water
against Doxorubicin Induced Cardiomyopathy. Journal of Krishna Institute of
Medical Sciences University.
https://doaj.org/article/c3316b67c43e49c58e7cdb48653bbc41

318
368. Chinasa, N. L. (2018). NUTRITIONAL HEALTH BENEFIT OF COCONUT
WATER. Innovare Journal of Food Sciences, 6–7.
https://innovareacademics.in/journals/index.php/ijfs/article/view/25334
369. Loki, A. L., & Rajamohan, T. (2003). Hepatoprotective and antioxidant effect
of tender coconut water on carbon tetrachloride induced liver injury in rats.
Indian Journal of Biochemistry & Biophysics, 40(5), 354–357.
https://pubmed.ncbi.nlm.nih.gov/22900330/
370. Martínez Leal, J., Valenzuela Suárez, L., Jayabalan, R., Huerta Oros, J., &
Escalante-Aburto, A. (2018). A review on health benefits of kombucha
nutritional compounds and metabolites. CyTA - Journal of Food, 16(1), 390–399.
https://doi.org/10.1080/19476337.2017.1410499,
https://www.tandfonline.com/doi/full/10.1080/19476337.2017.1410499
371. Yan, F., & Polk, D. B. (2011). Probiotics and immune health. Current Opinion
in Gastroenterology, 27(6), 496–501.
https://doi.org/10.1097/mog.0b013e32834baa4d,
https://pubmed.ncbi.nlm.nih.gov/21897224/
372. FoodData Central. (2019). Usda.gov.
https://fdc.nal.usda.gov/fdc-app.html#/food-details/167747/nutrients
373. Russo, M., Bonaccorsi, I., Torre, G., Sarò, M., Dugo, P., & Mondello, L. (2014).
Underestimated sources of flavonoids, limonoids and dietary fibre: Availability in
lemon’s by-products. Journal of Functional Foods, 9, 18–26.
https://doi.org/10.1016/j.jff.2014.04.004,
https://www.sciencedirect.com/science/article/abs/pii/S1756464614001364
374. Mas-Capdevila, A., Teichenne, J., Domenech-Coca, C., Caimari, A., Del Bas, J.
M., Escoté, X., & Crescenti, A. (2020). Effect of Hesperidin on Cardiovascular
Disease Risk Factors: The Role of Intestinal Microbiota on Hesperidin
Bioavailability. Nutrients, 12(5), 1488. https://doi.org/10.3390/nu12051488,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284956/
375. Kato, Y., Domoto, T., Hiramitsu, M., Katagiri, T., Sato, K., Miyake, Y., Aoi, S.,
Ishihara, K., Ikeda, H., Umei, N., Takigawa, A., & Harada, T. (2014). Effect on
Blood Pressure of Daily Lemon Ingestion and Walking. Journal of Nutrition and
Metabolism, 2014, 1–6. https://doi.org/10.1155/2014/912684,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003767/
376. Entezari, M., Aslani, N., Askari, G., Maghsoudi, Z., & Maracy, M. (2016). Effect
of garlic and lemon juice mixture on lipid profile and some cardiovascular risk
factors in people 30-60 years old with moderate hyperlipidaemia: A randomized
clinical trial. International Journal of Preventive Medicine, 7(1), 95.

319
https://doi.org/10.4103/2008-7802.187248,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977979/
377. Liya, S. J., & Siddique, R. (2018). Determination of antimicrobial activity of
some commercial fruit (apple, papaya, lemon and strawberry) against bacteria
causing urinary tract infection. European Journal of Microbiology and
Immunology, 8(3), 95–99. https://doi.org/10.1556/1886.2018.00014,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186015/
378. ER Ekawati and W Darmanto 2019 IOP Conf. Ser.: Earth Environ. Sci. 217
012023, Lemon (Citrus limon) Juice Has Antibacterial Potential against
Diarrhea-Causing Pathogen,
https://iopscience.iop.org/article/10.1088/1755-1315/217/1/012023/pdf
379. Chambial, S., Dwivedi, S., Shukla, K. K., John, P. J., & Sharma, P. (2013).
Vitamin C in Disease Prevention and Cure: An Overview. Indian Journal of
Clinical Biochemistry, 28(4), 314–328.
https://doi.org/10.1007/s12291-013-0375-3,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783921/
380. Shibuya, S., Ozawa, Y., Toda, T., Watanabe, K., Tometsuka, C., Ogura, T.,
Koyama, Y., & Shimizu, T. (2014). Collagen peptide and vitamin C additively
attenuate age-related skin atrophy in Sod1-deficient mice. Bioscience,
Biotechnology, and Biochemistry, 78(7), 1212–1220.
https://doi.org/10.1080/09168451.2014.915728,
https://www.tandfonline.com/doi/full/10.1080/09168451.2014.915728
381. Es, W., S, M., & Dh, H. (2006). Immune-enhancing Role of Vitamin C and Zinc
and Effect on Clinical Conditions. Annals of Nutrition & Metabolism.
https://pubmed.ncbi.nlm.nih.gov/16373990/
382. Chandran, B., & Goel, A. (2012). A Randomized, Pilot Study to Assess the
Efficacy and Safety of Curcumin in Patients with Active Rheumatoid Arthritis.
Phytotherapy Research, 26(11), 1719–1725. https://doi.org/10.1002/ptr.4639,
https://pubmed.ncbi.nlm.nih.gov/22407780/
383. Kunnumakkara, A. B., Bordoloi, D., Padmavathi, G., Monisha, J., Roy, N. K.,
Prasad, S., & Aggarwal, B. B. (2016). Curcumin, the golden nutraceutical:
multitargeting for multiple chronic diseases. British Journal of Pharmacology,
174(11), 1325–1348. https://doi.org/10.1111/bph.13621,
https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.13621
384. Hadi, A., Pourmasoumi, M., Ghaedi, E., & Sahebkar, A. (2019). The effect of
Curcumin/Turmeric on blood pressure modulation: A systematic review and
meta-analysis. Pharmacological Research, 150, 104505.

320
https://doi.org/10.1016/j.phrs.2019.104505,
https://pubmed.ncbi.nlm.nih.gov/31647981/
385. Qin, S., Huang, L., Gong, J., Shen, S., Huang, J., Ren, H., & Hu, H. (2017).
Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in
patients with cardiovascular risk factors: a meta-analysis of randomized
controlled trials. Nutrition Journal, 16(1).
https://doi.org/10.1186/s12937-017-0293-y,
https://pubmed.ncbi.nlm.nih.gov/29020971/
386. Turmeric | Complementary and alternative therapy | Cancer Research UK.
(2013). Cancerresearchuk.org.
https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/co
mplementary-alternative-therapies/individual-therapies/turmeric
387. Giordano, A., & Tommonaro, G. (2019). Curcumin and Cancer. Nutrients,
11(10), 2376. https://doi.org/10.3390/nu11102376,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835707/
388. Radomska-Leśniewska, D. M., Osiecka-Iwan, A., Hyc, A., Góźdź, A.,
Dąbrowska, A. M., & Skopiński, P. (2019). Therapeutic potential of curcumin in
eye diseases. Central European Journal of Immunology, 44(2), 181–189.
https://doi.org/10.5114/ceji.2019.87070,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745545/
389. Cao, J., Wang, T., & Wang, M. (2018). Investigation of the anti-cataractogenic
mechanisms of curcumin through in vivo and in vitro studies. BMC
Ophthalmology, 18(1). https://doi.org/10.1186/s12886-018-0711-8,
https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12886-018-0711-
8
390. Laura Fusar-Poli, Lucia Vozza, Alberto Gabbiadini, Antonio Vanella, Ilaria
Concas, Silvia Tinacci, Antonino Petralia, Maria Salvina Signorelli & Eugenio
Aguglia (2020) Curcumin for depression: a meta-analysis, Critical Reviews in
Food Science and Nutrition, 60:15, 2643-2653, DOI:
10.1080/10408398.2019.1653260,
https://www.tandfonline.com/doi/full/10.1080/10408398.2019.1653260?scroll
=top&needAccess=true
391. Ramaholimihaso, T., Bouazzaoui, F., & Kaladjian, A. (2020). Curcumin in
Depression: Potential Mechanisms of Action and Current Evidence—A Narrative
Review. Frontiers in Psychiatry, 11. https://doi.org/10.3389/fpsyt.2020.572533,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728608/
392. Panahi, Yunes & Fazlolahzadeh, Omid & Atkin, Stephen & Majeed,
Muhammed & Butler, Alexandra & Johnston, Thomas & Sahebkar, Amirhossein.

321
(2018). Evidence of curcumin and curcumin analogue effects in skin diseases: A
narrative review. Journal of cellular physiology. 234. 10.1002/jcp.27096,
https://www.researchgate.net/publication/326830448_Evidence_of_curcumin_a
nd_curcumin_analogue_effects_in_skin_diseases_A_narrative_review
393. Vollono, L., Falconi, M., Gaziano, R., Iacovelli, F., Dika, E., Terracciano, C.,
Bianchi, L., & Campione, E. (2019). Potential of Curcumin in Skin Disorders.
Nutrients, 11(9). https://doi.org/10.3390/nu11092169,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770633/
394. (PDF) Antioxidant potential and health benefits of cumin. (n.d.).
ResearchGate. Retrieved April 14, 2022, from
https://www.researchgate.net/publication/348972745_Antioxidant_potential_a
nd_health_benefits_of_cumin
395. Fatima, T., And Kashmir, J., Beenish, I., Kashmir, S., Naseer, I., Gani, I., Qadri, I.,
Kashmir, J., Beenish, B., Naseer, G., Gani, T., Qadri, T., & Bhat. (2018). Antioxidant
potential and health benefits of cumin. ~ 232 ~ Journal of Medicinal Plants
Studies, 6(2), 232–236.
https://www.plantsjournal.com/archives/2018/vol6issue2/PartD/6-2-28-858.pdf
396. Singletary, K. W. (2021). Cumin. Nutrition Today, 56(3), 144–151.
https://doi.org/10.1097/nt.0000000000000479,
https://journals.lww.com/nutritiontodayonline/Fulltext/2021/05000/Cumin__Pot
ential_Health_Benefits.8.aspx
397. Johri, R. (2011). Cuminum cyminum and Carum carvi: An update.
Pharmacognosy Reviews, 5(9), 63. https://doi.org/10.4103/0973-7847.79101,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210012/
398. Singletary, K. (2021). Cardamom: Potential Health Benefits. Nutrition Today.
https://doi.org/10.1097/NT.0000000000000507,
https://journals.lww.com/nutritiontodayonline/Abstract/9000/Cardamom__Poten
tial_Health_Benefits.99942.aspx
399. Daneshi-Maskooni, M., Keshavarz, S. A., Mansouri, S., Qorbani, M., Alavian, S.
M., Badri-Fariman, M., Jazayeri-Tehrani, S. A., & Sotoudeh, G. (2017). The effects
of green cardamom on blood glucose indices, lipids, inflammatory factors,
paraxonase-1, sirtuin-1, and irisin in patients with nonalcoholic fatty liver
disease and obesity: study protocol for a randomized controlled trial. Trials, 18.
https://doi.org/10.1186/s13063-017-1979-3,
https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-017-1979-3
400. Pearley Jesylne, Subasree Soundarajan , Karthikeyan Murthykumar,
Meenakshi. M. The Role of Cardamom Oil in Oral Health: A Short Review.
Research J. Pharm. and Tech. 9(3): Mar., 2016; Page 272-274. doi:

322
10.5958/0974-360X.2016.00050.0,
https://rjptonline.org/HTMLPaper.aspx?Journal=Research%20Journal%20of%20
Pharmacy%20and%20Technology;PID=2016-9-3-19
401. Neelakantan, N., Narayanan, M., de Souza, R. J., & van Dam, R. M. (2014).
Effect of fenugreek (Trigonella foenum-graecumL.) intake on glycemia: a
meta-analysis of clinical trials. Nutrition Journal, 13(1).
https://doi.org/10.1186/1475-2891-13-7,
https://nutritionj.biomedcentral.com/articles/10.1186/1475-2891-13-7
402. Wani, S. A., & Kumar, P. (2018). Fenugreek: A review on its nutraceutical
properties and utilization in various food products. Journal of the Saudi Society
of Agricultural Sciences, 17(2), 97–106.
https://doi.org/10.1016/j.jssas.2016.01.007,
https://www.sciencedirect.com/science/article/pii/S1658077X15301065
403. Fenugreek. (n.d.). NCCIH. https://www.nccih.nih.gov/health/fenugreek
404. Prachayasittikul, V., Prachayasittikul, S., Ruchirawat, S., & Prachayasittikul, V.
(2018). Coriander (Coriandrum sativum): A promising functional food toward the
well-being. Food Research International (Ottawa, Ont.), 105, 305–323.
https://doi.org/10.1016/j.foodres.2017.11.019,
https://pubmed.ncbi.nlm.nih.gov/29433220/
405. Singletary, Keith. (2016). Coriander: Overview of Potential Health Benefits.
Nutrition Today. 51. 151-161. 10.1097/NT.0000000000000159.
https://www.researchgate.net/publication/303776980_Coriander_Overview_of_
Potential_Health_Benefits
406. FoodData Central. (n.d.). Fdc.nal.usda.gov.
https://fdc.nal.usda.gov/fdc-app.html#/food-details/1103956/nutrients
407. Ahmad, A., Khan, R. A., & Mesaik, M. A. (2009). Anti inflammatory effect of
natural honey on bovine thrombin-induced oxidative burst in phagocytes.
Phytotherapy Research: PTR, 23(6), 801–808. https://doi.org/10.1002/ptr.2648,
https://pubmed.ncbi.nlm.nih.gov/19142984/
408. Hegazi, A. G., & Abd El-Hady, F. K. (2009). Influence of Honey on the
Suppression of Human Low Density Lipoprotein (LDL) Peroxidation (In Vitro).
Evidence-Based Complementary and Alternative Medicine, 6(1), 113–121.
https://doi.org/10.1093/ecam/nem071,
https://pubmed.ncbi.nlm.nih.gov/18955249/
409. Mandal, M. D., & Mandal, S. (2011). Honey: its medicinal property and
antibacterial activity. Asian Pacific Journal of Tropical Biomedicine, 1(2),
154–160. https://doi.org/10.1016/s2221-1691(11)60016-6,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609166/

323
410. Albaridi, N. A. (2019). Antibacterial Potency of Honey. International Journal
of Microbiology, 2019, 1–10. https://doi.org/10.1155/2019/2464507,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589292/
411. GHOSH, S., & PLAYFORD, R. J. (2003). Bioactive natural compounds for the
treatment of gastrointestinal disorders. Clinical Science, 104(6), 547–556.
https://doi.org/10.1042/cs20030067,
https://pubmed.ncbi.nlm.nih.gov/12641494/
412. Albaridi, N. A. (2019). Antibacterial Potency of Honey. International Journal
of Microbiology, 2019, 1–10. https://doi.org/10.1155/2019/2464507,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589292/
413. Zbuchea, A. (2014). Up-to-date use of honey for burns treatment. Annals of
Burns and Fire Disasters, 27(1), 22–30.
https://pubmed.ncbi.nlm.nih.gov/25249844/
414. International Archives of Medicine. (2015). International Archives of
Medicine. https://doi.org/10.3823/434,
https://pubmed.ncbi.nlm.nih.gov/22822475/
415. Yeh, H.-F., Luo, C.-Y., Lin, C.-Y., Cheng, S.-S., Hsu, Y.-R., & Chang, S.-T. (2013).
Methods for Thermal Stability Enhancement of Leaf Essential Oils and Their
Main Constituents from Indigenous Cinnamon (Cinnamomum osmophloeum).
Journal of Agricultural and Food Chemistry, 61(26), 6293–6298.
https://doi.org/10.1021/jf401536y, https://pubmed.ncbi.nlm.nih.gov/23738884/
416. Chang, S.-T., Chen, P.-F., & Chang, S.-C. (2001). Antibacterial activity of leaf
essential oils and their constituents from Cinnamomum osmophloeum. Journal
of Ethnopharmacology, 77(1), 123–127.
https://doi.org/10.1016/s0378-8741(01)00273-2,
https://pubmed.ncbi.nlm.nih.gov/11483389/
417. Wang, S.-Y., Chen, P.-F., & Chang, S.-T. (2005). Antifungal activities of
essential oils and their constituents from indigenous cinnamon (Cinnamomum
osmophloeum) leaves against wood decay fungi. Bioresource Technology, 96(7),
813–818. https://doi.org/10.1016/j.biortech.2004.07.010,
https://pubmed.ncbi.nlm.nih.gov/15607195/
418. Gruenwald, J., Freder, J., & Armbruester, N. (2010). Cinnamon and Health.
Critical Reviews in Food Science and Nutrition, 50(9), 822–834.
https://doi.org/10.1080/10408390902773052,
https://www.researchgate.net/publication/47350289_Cinnamon_and_Health
419. Pham, A. Q., Kourlas, H., & Pham, D. Q. (2007). Cinnamon Supplementation
in Patients with Type 2 Diabetes Mellitus. Pharmacotherapy, 27(4), 595–599.

324
https://doi.org/10.1592/phco.27.4.595,
https://pubmed.ncbi.nlm.nih.gov/17381386/
420. Zhu, M., Carvalho, R., Scher, A., & Wu, C. D. (2011). Short-term germ-killing
effect of sugar-sweetened cinnamon chewing gum on salivary anaerobes
associated with halitosis. The Journal of Clinical Dentistry, 22(1), 23–26.
https://europepmc.org/article/med/21290983
421. G.T., W., Villeneuve, N. F., Lamore, S. D., Bause, A. S., Jiang, T., & Zhang, D. D.
(2010). The Cinnamon-Derived Dietary Factor Cinnamic Aldehyde Activates the
Nrf2-Dependent Antioxidant Response in Human Epithelial Colon Cells.
Molecules, 15(5), 3338–3355. https://doi.org/10.3390/molecules15053338,
https://pubmed.ncbi.nlm.nih.gov/20657484/
422. Akilen, R., Pimlott, Z., Tsiami, A., & Robinson, N. (2013). Effect of short-term
administration of cinnamon on blood pressure in patients with prediabetes and
type 2 diabetes. Nutrition, 29(10), 1192–1196.
https://doi.org/10.1016/j.nut.2013.03.007,
https://pubmed.ncbi.nlm.nih.gov/23867208/
423. Wainstein, J., Stern, N., Heller, S., & Boaz, M. (2011). Dietary Cinnamon
Supplementation and Changes in Systolic Blood Pressure in Subjects with Type
2 Diabetes. Journal of Medicinal Food, 14(12), 1505–1510.
https://doi.org/10.1089/jmf.2010.0300,
https://pubmed.ncbi.nlm.nih.gov/21861719/
424. Rao, P. V., & Gan, S. H. (2014). Cinnamon: A Multifaceted Medicinal Plant.
Evidence-Based Complementary and Alternative Medicine, 2014, 1–12.
https://doi.org/10.1155/2014/642942,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003790/
425. Dhuley, J. N. (1999). Anti-oxidant effects of cinnamon (Cinnamomum verum)
bark and greater cardamom (Amomum subulatum) seeds in rats fed high fat
diet. Indian Journal of Experimental Biology, 37(3), 238–242.
https://pubmed.ncbi.nlm.nih.gov/10641152/
426. FoodData Central. (n.d.). Fdc.nal.usda.gov. Retrieved April 14, 2022, from
https://fdc.nal.usda.gov/fdc-app.html#/food-details/169279/nutrients
427. Shahbazi, R., Sharifzad, F., Bagheri, R., Alsadi, N., Yasavoli-Sharahi, H., &
Matar, C. (2021). Anti-Inflammatory and Immunomodulatory Properties of
Fermented Plant Foods. Nutrients, 13(5), 1516.
https://doi.org/10.3390/nu13051516 ,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147091/
428. Raak, C., Ostermann, T., Boehm, K., & Molsberger, F. (2014). Regular
Consumption of Sauerkraut and Its Effect on Human Health: A Bibliometric

325
Analysis. Global Advances in Health and Medicine, 3(6), 12–18.
https://doi.org/10.7453/gahmj.2014.038,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268643/
429. Dimidi, E., Cox, S. R., Rossi, M., & Whelan, K. (2019). Fermented Foods:
Definitions and Characteristics, Impact on the Gut Microbiota and Effects on
Gastrointestinal Health and Disease. Nutrients, 11(8), 1806.
https://doi.org/10.3390/nu11081806,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723656/
430. Mekkes, M. C., Weenen, T. C., Brummer, R. J., & Claassen, E. (2014). The
development of probiotic treatment in obesity: a review. Beneficial Microbes,
5(1), 19–28. https://doi.org/10.3920/BM2012.0069,
https://pubmed.ncbi.nlm.nih.gov/23886977/
431. Omar, J. M., Chan, Y.-M., Jones, M. L., Prakash, S., & Jones, P. J. H. (2013).
Lactobacillus fermentum and Lactobacillus amylovorus as probiotics alter body
adiposity and gut microflora in healthy persons. Journal of Functional Foods,
5(1), 116–123. https://doi.org/10.1016/j.jff.2012.09.001,
https://www.sciencedirect.com/science/article/pii/S1756464612001399
432. Ritchie, M. L., & Romanuk, T. N. (2012). A Meta-Analysis of Probiotic Efficacy
for Gastrointestinal Diseases. PLoS ONE, 7(4), e34938.
https://doi.org/10.1371/journal.pone.0034938,
https://pubmed.ncbi.nlm.nih.gov/22529959/
433. Zhou, X., Liu, H., Zhang, J., Mu, J., Zalan, Z., Hegyi, F., Takács, K., Zhao, X., &
Du, M. (2019). Protective effect of Lactobacillus fermentum CQPC04 on dextran
sulfate sodium–induced colitis in mice is associated with modulation of the
nuclear factor-κB signaling pathway. Journal of Dairy Science, 102(11),
9570–9585. https://doi.org/10.3168/jds.2019-16840,
https://www.sciencedirect.com/science/article/pii/S0022030219307593
434. FoodData Central. (n.d.). Fdc.nal.usda.gov.
https://fdc.nal.usda.gov/fdc-app.html#/food-details/170392/nutrients
435. Rumila Sitaram Kumar, T., Dhiman, M., & Kumari. (2021). Fermented
Vegetables: Kimchi and Its Health Benefits. Journal of Science and Technology,
6(3), pp. https://doi.org/10.46243/jst.2021.v6.i3.pp13-16,
http://jst.org.in/wp-content/uploads/2021/05/03.-Fermented-Vegetables-Kimchi
-and-Its-Health-Benefits.pdf
436. Kim, E. K., An, S.-Y., Lee, M.-S., Kim, T. H., Lee, H.-K., Hwang, W. S., Choe, S. J.,
Kim, T.-Y., Han, S. J., Kim, H. J., Kim, D. J., & Lee, K.-W. (2011). Fermented kimchi
reduces body weight and improves metabolic parameters in overweight and
obese patients. Nutrition Research, 31(6), 436–443.

326
https://doi.org/10.1016/j.nutres.2011.05.011,
https://www.sciencedirect.com/science/article/abs/pii/S027153171100114X?via
%3Dihub
437. DiRienzo, D. B. (2013). Effect of probiotics on biomarkers of cardiovascular
disease: implications for heart-healthy diets. Nutrition Reviews, 72(1), 18–29.
https://doi.org/10.1111/nure.12084, https://pubmed.ncbi.nlm.nih.gov/24330093/
438. Ohashi, Y., Nakai, S., Tsukamoto, T., Masumori, N., Akaza, H., Miyanaga, N.,
Kitamura, T., Kawabe, K., Kotake, T., Kuroda, M., Naito, S., Koga, H., Saito, Y.,
Nomata, K., Kitagawa, M., & Aso, Y. (2002). Habitual Intake of Lactic Acid
Bacteria and Risk Reduction of Bladder Cancer. Urologia Internationalis, 68(4),
273–280. https://doi.org/10.1159/000058450,
https://pubmed.ncbi.nlm.nih.gov/12053032/
439. Zhang, K., Dai, H., Liang, W., Zhang, L., & Deng, Z. (2018). Fermented dairy
foods intake and risk of cancer. International Journal of Cancer, 144(9),
2099–2108. https://doi.org/10.1002/ijc.31959,
https://pubmed.ncbi.nlm.nih.gov/30374967/
440. Kwak, S.-H., Cho, Y.-M., Noh, G.-M., & Om, A.-S. (2014). Cancer Preventive
Potential of Kimchi Lactic Acid Bacteria (Weissella cibaria, Lactobacillus
plantarum). Journal of Cancer Prevention, 19(4), 253–258.
https://doi.org/10.15430/JCP.2014.19.4.253
https://pubmed.ncbi.nlm.nih.gov/25574459/
441. FoodData Central. (2020). Usda.gov.
https://fdc.nal.usda.gov/fdc-app.html#/food-details/170931/nutrients
442. Institute, M. S. (n.d.). McCormick Science Institute. Retrieved April 14, 2022,
from
https://www.mccormickscienceinstitute.com/our-research/scientific-overviews/m
si-funded-paper-potential-health-benefits-of-black-pepper
443. Butt, Masood & Pasha, Imran & Sultan, Muhammad & Randhawa,
Muhammad & Saeed, Farhan & Ahmed, Waqas. (2012). Black Pepper and
Health Claims: A Comprehensive Treatise. Critical Reviews in Food Science and
Nutrition - CRIT REV FOOD SCI NUTR. 53. 10.1080/10408398.2011.571799.
https://www.researchgate.net/publication/254217270_Black_Pepper_and_Heal
th_Claims_A_Comprehensive_Treatise
444. Salehi, B., Zakaria, Z. A., Gyawali, R., Ibrahim, S. A., Rajkovic, J., Shinwari, Z.
K., Khan, T., Sharifi-Rad, J., Ozleyen, A., Turkdonmez, E., Valussi, M., Tumer, T. B.,
Monzote Fidalgo, L., Martorell, M., & Setzer, W. N. (2019). Piper Species: A
Comprehensive Review on Their Phytochemistry, Biological Activities and
Applications. Molecules, 24(7), 1364.

327
https://doi.org/10.3390/molecules24071364,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479398/
445. Salehi, B., Zakaria, Z. A., Gyawali, R., Ibrahim, S. A., Rajkovic, J., Shinwari, Z.
K., Khan, T., Sharifi-Rad, J., Ozleyen, A., Turkdonmez, E., Valussi, M., Tumer, T. B.,
Monzote Fidalgo, L., Martorell, M., & Setzer, W. N. (2019). Piper Species: A
Comprehensive Review on Their Phytochemistry, Biological Activities and
Applications. Molecules, 24(7), 1364.
https://doi.org/10.3390/molecules24071364,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479398/
446. Ms, B., I, P., Mt, S., Ma, R., F, S., & W, A. (2013). Black Pepper and Health
Claims: A Comprehensive Treatise. Critical Reviews in Food Science and
Nutrition. https://pubmed.ncbi.nlm.nih.gov/23768180/
447. Shah, S., Shah, G., Singh, S., Gohil, P., Chauhan, K., Shah, K., & Chorawala, M.
(2011). Effect of piperine in the regulation of obesity-induced dyslipidemia in
high-fat diet rats. Indian Journal of Pharmacology, 43(3), 296.
https://doi.org/10.4103/0253-7613.81516,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113382/
448. Du, Y., Chen, Y., Fu, X., Gu, J., Sun, Y., Zhang, Z., Xu, J., & Qin, L. (2020). Effects
of piperine on lipid metabolism in high-fat diet induced obese mice. Journal of
Functional Foods, 71, 104011. https://doi.org/10.1016/j.jff.2020.104011,
https://www.sciencedirect.com/science/article/pii/S1756464620302358
449. Ms, B., I, P., Mt, S., Ma, R., F, S., & W, A. (2013). Black Pepper and Health
Claims: A Comprehensive Treatise. Critical Reviews in Food Science and
Nutrition. https://pubmed.ncbi.nlm.nih.gov/23768180/

328

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