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Journal of Psychiatric and Mental Health Nursing, 2011, 18, 744–750

Quality of Life Enjoyment and Satisfaction


Questionnaire – short form for quality of life
assessments in clinical practice: a psychometric study
D . S T E VA N O V I C m d
Department of Psychiatry, General Hospital Sombor, Sombor, Serbia

Keywords: mental illness, quality of Accessible summary


life, reliability, responsiveness, validity

Correspondence:
• The measurement characteristics of the Quality of Life Enjoyment and Satisfaction
Questionnaire (Q-LES-Q) for quality of life (QOL) assessments in the clinical
D. Stevanovic
settings were evaluated.
Department of Psychiatry
General Hospital Sombor • The Q-LES-Q – SF showed sound internal consistency, test–retest reliability, and
Apatinski put 38, 25000 Sombor
convergent and criterion validity, with 80% sensitivity and 100% specificity.
Serbia • The Q-LES-Q – SF could produce reliable, valid and sensitive assessments of QOL
E-mail: dejanstevanovic@eunet.rs in routine psychiatric practice.

Accepted for publication: 26 March


Abstract
2011
The Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q) and its short
doi: 10.1111/j.1365-2850.2011.01735.x
form (Q-LES-Q – SF) are among the most frequently used outcome measures in
psychiatry research. The aim of this study was to analyse the measurement properties
of the Q-LES-Q – SF for quality of life assessments in the clinical settings. Fifty-seven
adults with a psychiatric diagnosis participated. Psychometric evaluation included
descriptive analysis, internal consistency, test–retest reliability, validity, sensitivity
and responsiveness analysis. The amount of missing data was 5.3%, while no floor or
ceiling effects were observed. The internal consistency and test–retest coefficients were
0.9 and 0.93, respectfully. Almost all items significantly correlated to the total score
and other measures used in the study, with the correlations ranging 0.41–0.81. Finally,
the responsiveness parameters indicated the Q-LES-Q – SF is 80% sensitive and 100%
specific measure. This preliminary analysis of the Q-LES-Q – SF demonstrated that it
could produce reliable and valid clinical assessments of quality of life.

years. Rapidly, QOL entered many researches, mainly


Introduction
because we have reached some consensus on its measure-
Quality of life (QOL), as one of the most important ment in clinical trials, but there are very limited reports
patient-reported outcome, represents how an individual about its routine use in clinical practice (Acquadro et al.
perceives the impacts of a health condition and its treat- 2003, Szende et al. 2005).
ment on his or her daily living. It has become an essential In a review from 1999, the authors evaluated some
part in research and recognized as an important end point conceptual and methodological issues related to QOL
in the clinical settings. The purpose of measuring QOL in assessment in mental health research. Among other find-
research is to compare groups of patients (usually over ings, they observed that more research is required as related
relatively short periods) with the focus on the assessments to QOL instruments in order to use them as clinically
of their performance. Such situations are different from appropriate assessment procedures (Gladis et al. 1999).
clinical practice, where the purpose of measurement is to This implies that clinically useful QOL instruments need to
assess change in individual patients, sometimes for many be feasible, reliable, valid and sensitive to change.

744 © 2011 Blackwell Publishing


Q-LES-Q – SF in clinical practice

The Quality of Life Enjoyment and Satisfaction Ques- Table 1


Demographic characteristics of 57 subjects
tionnaire (Q-LES-Q) is among the most frequently used
Age, years (M, SD) 47.16, 9.22
outcome measures in psychiatry research (Endicott et al.
Gender, n (%) 38 (66.7) M, 19 (33.3) F
1993). It is a generic, self-reported QOL measure assessing
Marital status, 25 (43.87) married/live with a partner,
the physical health, subjective feelings, leisure activities, n (%) 22 (38.59) never married,
social relationships, general activities, satisfaction with 10 (17.54) separated/divorced/a
medications and life satisfaction domains. The Quality of partner died
Educational level, 11 (19.29) primary school,
Life Enjoyment and Satisfaction Questionnaire – Short n (%) 39 (68.43) secondary school,
form (Q-LES-Q – SF) was developed from the original, 7 (12.28) high school/university degree
long form, fully representing its concept. The Q-LES-Q – Occupational status, 21 (36.84) full- or part-time work,
n (%) 16 (28.07) retired,
SF produced psychometrically sound QOL assessments in 19 (33.33) not employed,
different groups of people with psychiatric illnesses, in 1 (1.75) college student
terms of good reliability, validity and sensitivity to change Psychiatric diagnosis 20 (35.08) Schizophrenia, schizotypal and
according to the delusional disorders (F20-F29),
(Endicott et al. 1993, 2007, Müllerová et al. 2001, Ritsner
ICD-10 categories 16 (28.07) Mood disorders (F30-F39),
et al. 2002, Rucci et al. 2007, Mick et al. 2008, Hope et al. (WHO, 1993), n (%) 11 (19.29) Anxiety, stress-related and
2009, Wyrwich et al. 2009). somatoform disorders F40-F48,
This study was organized with the aims to analyse the 10 (17.56) Disorders of adult personality
and behaviour (F60-F62)
measurement properties of the Q-LES-Q – SF and to
examine its ability to measure QOL in the clinical settings
using a Serbian sample. It was assumed that the measure
should possess appropriate measurement properties of an major medical problem (e.g. chronic illness, impairment),
evaluative measure to be used for assessing change in inability to read or write and living in an institution. All
individual patients (Fayers & Machin 2007). patients were diagnosed according to the International
Classification of Diseases (ICD – 10) [World Health
Organization (WHO) 1993] and to all was initiated
Methods
some kind of treatment, medications, social therapy and/or
psychotherapy.
Q-LES-Q – SF
Fifty-seven subjects who accepted to participate and
The Q-LES-Q – SF is a self-reported questionnaire, with 16 provided a written consent were assessed independently
items, derived from the general activities scale of the origi- (Table 1). However, each analysis below included only sub-
nal 93-item form (Endicott et al. 1993). It evaluates overall jects who provided all data.
enjoyment and satisfaction with physical health, mood,
work, household and leisure activities, social and family First assessment
relationships, daily functioning, sexual life, economic On the admission, each participant was evaluated on the
status, overall well-being and medications. Responses are Clinical Global Impression severity scale (CGIs) rated by a
scored on a 5-point scale (‘not at all or never’ to ‘frequently clinician and the Patient-reported Global Impression sever-
or all the time’), where higher scores indicate better enjoy- ity scale (PGIs) rated by a participant, both as a 7-point
ment and satisfaction with life (possible range 14–70). scale, from 1 – ‘extremely ill’ to 7 – ‘not ill at all’ (Endicott
Fourteen summated items create the total Q-LES-Q – SF et al. 1993). The Q-LES-Q – SF was completed afterwards.
score. Two last items, about medications and overall life
satisfaction, are considered independently. Second assessment
The MAPI Research Trust Institute developed the Serbian On the second appointment, 7 days later, the subjects were
version provided to the author by the developer J. Endicott, evaluated again and those who remained stable over this
PhD. The version was pre-tested in a small group of psychi- period completed the Q-LES-Q – SF. A ‘stable’ subject is
atric patients prior this study to test the cultural appropri- one whose health status has not changed in any domain
ateness and content validity (Fayers & Machin 2007). since the previous assessment.

Third assessment
Subjects and assessments
At the follow-up assessment, 4 weeks later, beside the CGIs,
All adults admitted to daily hospital for some psychiatric PGIs and the Q-LES-Q – SF, the Clinical Global Impression
treatment between December 2008 and January 2009 were improvement scale (CGIi) was completed by a clinician,
eligible. Exclusion criteria were the presence of any other from 0 – state unchanged to 6 – ideal improvement

© 2011 Blackwell Publishing 745


D. Stevanovic

(Endicott et al. 1993). The three indexes, CGIs, PGIs and between different people (sensitivity), and it should be able
CGIi, were the external criteria of change (anchors) and to detect QOL changes in unstable subjects (responsive-
each should significantly correlate with the Q-LES-Q – SF ness) (Fayers & Machin 2007).
(Fayers & Machin 2007). Thus, any change in the Q-LES-Q Internal consistency reliability was assessed by Cron-
– SF would be observed in the external criteria of change. bach’s alpha and it should exceed 0.7. Test–retest reliability
After the final assessment, all participants were assigned was analysed using the intraclass correlation coefficient
to two groups. The ‘unchanged’ group (n = 22) included (the two-way random method of absolute agreement) to
subjects without changes in mental health status from the derive the reliability coefficient (Streiner & Norman 2008).
first assessment and the ‘changed’ group (n = 14) included The retest took place 7 days later considering the 1-week
those subjects who improved over the study period (the time frame of the Q-LES-Q – SF. Test–retest reliability
improvement was measured as change in scores in two or should be at least 0.9 in order to evaluate the ability of the
more of the anchors used). During the follow-up period, two questionnaire in detecting changes important for individual
subjects worsened significantly, four were acutely diseased comparisons (Fayers & Machin 2007).
(a viral infection), five were discharged earlier (as a result of Eventually, the responsiveness was evaluated as the fol-
financial problems) and 10 refused to participate this time. lowing. First, the standard error of measurement (SEM)
After the approval from the Psychiatric Board about the was derived from the standard deviation of the sample,
involvement of all patients in the study activities, the Ethics from which was assessed the reliability, multiplied by
Comity of the author’s institution (General Hospital square root of (1 – the reliability) (Sprangers et al. 2002,
Sombor) approved the study. Crosby et al. 2004). For the SEM, 90% confidence inter-
vals (90% CI) were calculated around individual patient
scores, reflecting the questionnaire’s accuracy for indi-
Psychometric analysis
vidual assessments and clinical decision making (Williams
Descriptive analysis & Naylor 1992). Further, the SEM was converted into the
The number and distribution of missing data were exam- smallest detectable change (SDC) reflecting the smallest
ined to assess the acceptability of the questionnaire assum- within-individual change in score that could be interpreted
ing that this value should not be more than one-third of as a ‘real’ change, above measurement error in one indi-
unanswered items for an individual (Fayers & Machin vidual (Terwee et al. 2007). The SDC was calculated by
2007, Terwee et al. 2007). The distribution of responses for multiplying the z-score corresponding to the level of sig-
each item was assessed visually. Further, the mean, stan- nificance, the square root of 2 and the SEM. A z-score of
dard deviation, skewness and kurtosis for responses to 1.64 was chosen to reflect an acceptable 90% CI for clini-
every item were calculated (Ware & Gandek 1998). Finally, cal application to individual patients (Schmitt & Di Fabio
the percentage of responses on anchor points was exam- 2004). Finally, the minimal important difference (MID;
ined to detect floor or ceiling effects, which should not also known as minimal clinically important difference),
exceed 15% (Terwee et al. 2007). defined as the smallest difference in score perceived as
beneficial, was determined using mean change scores for
Analysis of validity patients with small but meaningful change according to
Three assumptions were considered for validity. All items some external criteria (Schmitt & Di Fabio 2004).
should be correlated minimally 0.4 to the total score cor- Change over the 4-week interval was analysed using
rected for overlap using Spearman’s correlation. These cor- three responsiveness indices at the individual patient level.
relations should not be substantially different between the Only data from all followed-up patients were used (de Vet
items, indicating that the amount of information to the total 2001, Schmitt & Di Fabio 2004). Reliable change propor-
concept being measured is similar for each item (Ware & tion – the proportion of the sample with change scores
Gandek 1998). Finally, the Q-LES-Q – SF should be signifi- exceeding the SDC, which is also sensitivity to change;
cantly correlated with the CGIs, PGIs and CGIi (P < 0.05, MID proportion – the proportion of the sample with
Spearman’s correlation) as the means of criterion validity. change scores exceeding the MID, and specificity to change
– the proportion of those who claimed perceiving no
Analysis of internal consistency reliability, test–retest change and their scores did not exceed the SDC.
reliability, sensitivity and responsiveness
It was assumed that the questionnaire should have appro-
Results
priate internally consistency reliability and it should be
stable in stable subjects (test–retest reliability, reproducibil- From the pre-testing, it was accepted that the Q-LES-Q –
ity), it should be sensitive to detect differences in QOL SF possesses culturally appropriate items with sufficient

746 © 2011 Blackwell Publishing


Q-LES-Q – SF in clinical practice

Table 2
Distributional data of the Q-LES-Q – SF items (n = 57)
Skewness Kurtosis
Items M SD Statistic Standard error Statistic Standard error
1. physical health 3.07 1.24 -0.37 0.316 -0.94 0.62
2. mood 2.86 1.11 -0.36 0.316 -0.98 0.62
3. work 2.13 0.51 0.45 0.316 3.79 0.62
4. household activities 3.16 1.01 -0.01 0.316 -0.63 0.62
5. social relationships 2.73 1.16 0.19 0.316 -0.73 0.62
6. family relationships 3.25 1.18 -0.44 0.316 -0.66 0.62
7. leisure time activities 2.96 1.05 -0.31 0.316 -0.65 0.62
8. ability to function in daily life 2.91 1.23 0.11 0.316 -1.07 0.62
9. sexual drive. interest and/or performance 2.75 1.18 -0.25 0.316 -1.2 0.62
10. economic status 2.34 1.15 0.51 0.316 -0.67 0.62
11. living/housing situation 3.17 1.23 -0.51 0.316 -0.73 0.62
12. ability to get around physically without feeling dizzy or falling 3.18 1.23 -0.23 0.316 -0.93 0.62
13. your vision in terms of ability to do work or hobbies 2.88 1.17 0.18 0.316 -0.91 0.62
14. overall sense of well-being 2.80 1.02 0.12 0.316 -0.7 0.62
Row total (1–14 item) 37.27 9.28 -0.67 0.316 0.53 0.62
15. medication 3.55 0.94 -0.33 0.316 -0.63 0.62
16. overall life satisfaction and contentment 3.04 1.08 0.14 0.267 -0.82 0.53
Q-LES-Q – SF, The Quality of Life Enjoyment and Satisfaction Questionnaire – Short form.

content validity. Only item that measures satisfaction with Table 3


Total Q-LES-Q – SF score at baseline and the 4-week follow up of
economic status possesses insufficient characteristics for
the groups
evaluative purposes.
Baseline score Follow-up score
The amount of missing data was 5.3% and none of the Group M (SD) M (SD)
subjects left more than one-third of unanswered items. ‘Changed’, n = 14 33.57 (6.24) 42.52 (8.48)
The data are particularly missing for the third item (‘sat- ‘Unchanged’, n = 22 45.02 (10.92) 44.76 (11.5)
isfaction with work’), whereas the majority of the sub- Q-LES-Q – SF, The Quality of Life Enjoyment and Satisfaction
jects were unemployed or retired. On the other hand, the Questionnaire – Short form.

group considered all possible responses and there were no


biased patterns in responding. The differences between Table 4
the distribution measures are roughly equivalent, except Responsiveness parameters for the Q-LES-Q – SF

between Item no. 3 (‘satisfaction with work’) and the Parameter Value

others, while no floor or ceiling effects were observed for Standard error of measurement (SEM) 2.74, 90% CI = ⫾4.49
Smallest detectable change (SDC) 6.34
the total and they were below 15% for all items. In Minimal important difference (MID) 8.95
Table 2 were given the distributional data of the Q-LES-Q Sensitivity to change 78.57%
– SF items. MID proportion 71.43%
Specificity to change 100%
Q-LES-Q – SF, The Quality of Life Enjoyment and Satisfaction
Validity Questionnaire – Short form.

All items, except Item no. 3 (r = 0.18), were significantly


correlated to the total score and the correlations ranged
between 0.41 and 0.81. Two last, uncommitted items about has not changed in any domain since the first assessment,
medications and overall life satisfaction, were correlated to while three subjects had not appeared to the testing. Test–
the total 0.66 and 0.83, respectfully. Finally, the Q-LES-Q retest reliability of Item no. 15 was 0.75 and 0.80 of Item
– SF score was significantly correlated with the CGIs, PGIs no. 16.
and CGIi, 0.89, 0.43 and 0.47 respectfully. In Table 3 were given the descriptive data of the ‘change’
and ‘unchanged’ group and in Table 4 the responsiveness
parameters. The SDC of the measure is almost 6.5, while
Internal consistency reliability, test–retest reliability,
the MID almost nine. The Q-LES-Q – SF is able to detect
sensitivity and responsiveness
changes in QOL in nearly 80% (sensitivity to change) of
The internal consistency reliability of the questionnaire those who claimed that there was change during the follow
was 0.90, while test–retest reliability was 0.93. Fifty-four up, while it detects 100% the absence of QOL change
subjects were retested, as the subjects whose health status when there was no real change (specificity to change).

© 2011 Blackwell Publishing 747


D. Stevanovic

The analysis of test–retest reliability, sensitivity and


Discussion
responsiveness confirmed the appropriateness of the
This psychometric study of the Q-LES-Q – SF examined its Q-LES-Q – SF for evaluative purposes (Fayers & Machin
measurement properties in a small sample of people with 2007). First, the Q-LES-Q – SF test–retest reliability is high,
psychiatric illnesses in Serbia. The study demonstrated 0.93, and this is appropriate for individual comparisons,
that, as a generic QOL questionnaire, the Q-LES-Q – SF implying its stability in repeated assessments (Streiner &
possesses appropriate measurement properties of an evalu- Norman 2008). Second, the approach used here to evaluate
ative measure for assessing QOL changes in individual the sensitivity and responsiveness to change is suitable for
patients. measures used in clinical practice (Wyrwich et al. 1999, de
In the entire questionnaire, the response rate was high Vet 2001, Schmitt & Di Fabio 2004). When the SEM is
and the amount of missing data was small. The mean considered for an instrument, clinicians will be aware of
values were roughly equivalent, as if the standard devia- the amount of the measurement error, while the SDC will
tions, and no floor or ceiling effects were observed. The guide them how much an individual has to change to be
distribution of the data has a negative skewness in a major- judged as having really changed. Appling this to the
ity of the items, although not significant, and a negative Q-LES-Q – SF, the SEM is 2.74 points of the total (with
kurtosis, both indicating the observations clustered less. ⫾4.49 in 90% confidence interval), while the SDC is 6.34,
Together, the results revealed the Q-LES-Q – SF is a feasible meaning that a clinician should consider the individual
measure, with good acceptability of the concept measured, score to be true score ⫾4.49 and that individual has to
i.e. life enjoyment and satisfaction, but it would rather change at least 6.34 points on the total, to be judged as
detect positive states within the concept. Nevertheless, item having really changed. On the same note, whereas the MID
no. 3 (‘satisfaction with work’) significantly differed from as the smallest difference in the score perceived as beneficial
the others, which was possible to explain by a high rate of is 8.95, an individual has to change nearly 9 points on the
the group unemployment. This item is suspected of having Q-LES-Q – SF to be considered as having clinically
lesser importance for clinical, routine evaluations, which meaningful change. Finally, considering the three respon-
will be explored with the future use of the measure. siveness indexes, reliable change proportion or sensitivity
The multivariable analysis showed the questionnaire to change, MID proportion and specificity to change, the
possesses appropriate convergent and criterion validity, as Q-LES-Q – SF is highly sensitive and specific. Based on the
well as internal consistency reliability, for a measure to be data, the questionnaire could detect in 80% of the cases
used in the clinical settings, but these parameters deserve those who have really changed in their QOL according to
more explorations. First, except Item no. 3 (‘satisfaction the external criteria, and could in 100% exclude those who
with work’), all items correlated significantly to the total have not really changed.
score, but the correlations are substantially different among Nevertheless, we should be aware that the above param-
the items, showing the amount of information provided eters, although robust and trustworthy, do not necessary
to the total score is different for each item (Williams & generalize to all situations and they were observed in a
Naylor 1992). This indicates that some items are more small group of patients (Wyrwich et al. 1999, Schmitt & Di
relevant or superior in reporting QOL than others are, Fabio 2004). Specially, other external criteria that will
which is best possible to examine using factor analysis. serve as anchors of change might be used for MID or
Factor analysis could identify the underlying constructs of clinicians might set a priori the MID of the Q-LES-Q – SF
the items, to sort them in subscales and to equalize the (Wyrwich et al. 2009). Additionally, if someone intends to
importance (Ware & Gandek 1998, Fayers & Machin use the measure for group comparisons, he or she must
2007). take into account the group effect, SDCgroup (Terwee et al.
Second, the correlations with the Global Clinical Index 2007).
indicate the Q-LES-Q – SF is valuable for evaluating illness Finally, the measurement characteristics of item no. 15
severity, but its value shall be explore in depth for people and no. 16, medications and overall life satisfaction, are
with different psychiatric conditions (Endicott et al. 1993). worth mentioning. The distribution data were satisfactory
Finally, the internal consistency reliability of the Q-LES-Q and they were highly correlated with the total Q-LES-Q –
– SF is high, 0.90, what pictures high homogeneity among SF, but both possess inappropriate reliability for individual
the items in measuring the intended concept, consistency in comparisons. Therefore, the responsiveness was not evalu-
giving a response across the items, but also might indicate ated and these items shall be used with precautions.
redundancy among the items (Streiner & Norman 2008). Comparing these findings with other validation studies
The internal consistency should be also evaluated using of the Q-LES-Q, the following was observed. The internal
factor analysis. consistency reliability coefficients of this version or the

748 © 2011 Blackwell Publishing


Q-LES-Q – SF in clinical practice

general activities scale, an equivalent to the short form, are construct and predictive, were not evaluated and it were
similar between the original (0.90) (Endicott et al. 1993), not including other QOL measures, whereas such are
Czech (0.90) (Müllerová et al. 2001), Hebrew (0.95) unavailable in Serbian. Finally, the sample in overall was
(Ritsner et al. 2002), Italian (0.92) (Rucci et al. 2007) and small and this limit the generalizability of the study to
the Serbian version (0.9). However, the test–retest reliabil- other settings.
ity coefficient is highest for the Serbian Q-LES-Q – SF In summary, this preliminary analysis of the Q-LES-Q –
(0.93). Finally, the authors that validated the Q-LES-Q – SF SF demonstrated that it is appropriate QOL questionnaire
for attention deficit – hyperactivity disorder reported that for routine, clinical assessments of individuals with psychi-
the minimally important difference anchored by clinical atric illnesses. It showed that the measure could produce
ratings is 3 points on the raw score, what equals the SEM reliable, valid and sensitive assessments of the individuals’
observed in this study (Mick et al. 2008). In two studies QOL. However, with awareness of the limitations of the
with bipolar disorder and generalized anxiety disorder, the present study and the questionnaire itself, further investi-
minimum clinically important Q-LES-Q (SF) score change gations will be needed. Future research will be directed to
was identified to be 11.89 and 6.80 points, respectfully evaluate its measurement properties in samples that are
(Endicott et al. 2007, Wyrwich et al. 2009). These findings more homogeneous, with different groups of patients. In
indicate that for measures such as the Q-LES-Q (SF) the particular, the issues arose during the study will be also
magnitude of the MID may vary depending on the specific analysed. In this way, the Q-LES-Q – SF will evolve into a
population of interest and as well as of the purpose of gold standard for QOL evaluations in routine psychiatric
assessment. practice, as it is in research.
There are several limitations of the study. First, the
heterogeneity of the sample (gender, age and diagnoses)
Acknowledgments and disclosures
could explain high reliability coefficients. Second, a small
number of participants did not allowed to study changes I would like to thank Professor Jean Endicott and to all
in mental health in those who deteriorated during people with psychiatric illness included in the study. The
the study period. Third, other aspects of validity, like author has no competing interests.

Gladis M.M., Gosch E.A., Dishuk N.M., et al. Schmitt J.S. & Di Fabio R.P. (2004) Reliable
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750 © 2011 Blackwell Publishing

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