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Biology
a. Mediastinum – middle most part of thoracic Breathing – mechanism of taking in and out of carbon
cavity dioxide
b. Pleural – protects and holds the lungs
Digestive System – breakdown of food
*pleurisy – symptoms
- absorb nutrients
*pleural effusion – may tubig
- excretion
c. Pericardial – covering of the heart
↓ ↓
covering heart
Excretory System 78% Nitrogen
↑ ↑
21% Oxygen
*Unidirectional Flow 3. Blood Vessel
Parabronchi – connects the anterior and posterior a. arteries – away from the heart ; O2, blood
b. arterioles – small arteries
Mammalian Lung System
c. veins – towards the heart ; deoxygenated blood
Nose & mouth d. venules – small veins
Pharynx or throat e. capillaries – connection of arteries and veins
Trachea – voice box - site of exchange of materials
Trachea – windpipe
Bronchus
Bronchioles MECHANISM
Alveoli Vasolidation – widening of blood vessel
Lungs
Vasoconstriction – narrowing of the blood vessel
CARDIOVASCULAR SYSTEM
PARTS OF BLOOD VESSEL:
1. Circulation – flow of blood in the body
2. Open Circulatory System – presence of
hemocoel & hemolymph → Lumen – space where blood flows
3. Closed Circulatory System – presence of
capillaries & blood → inner layer ; interior surface of blood
*interconnection of veins and arteries vessel
4. Single Loop – single circulation ; 2 ex. fishes
→ assists blood flow
5. Double Loop - double circulation ; 3-4 ex.
mammals, birds, reptiles, amphibians → outermost layer of blood
vessel
Mammalian Circulatory System
LEUKOCYTES
SIGNALS OF INFLAMMATION
1. Macrophages – large irregular phagocytotic
WBCs 1. Rubor - redness
Phagocytotic – cell eating 2. Calor - heat
3. Tumor - swell
+ pinocytosis – cell drinking 4. Dolor - pain
5. Functio Laesa – loss of function
2. Neutrophil – engulfs and releases disinfecting
monocytes
ADAPTIVE IMMUNE SYSTEM - helps to mature B cell
- activates cytotoxic cells
- w/ memory
2. CD8+ cells
- w/ discrimination
- cytotoxic T cells
- slower
- lysis virus and tumor infected cell
TWO TYPES OF ADAPTIVE RESPONSES: 3. Memory T-cells
- can be a CD4+ or CD8+ that already
1. Humoral Immune Response encounters pathogens
2. Cell-Mediated Immune Response 4. Regulatory T-cell
I. Humoral Immune Response - suppressor T-cells
- maintains and regulates T-cells
Antibodies – substances that fight and react B. B cells (bursa of fabricius)
with pathogens Originate: bone marrow
Antigens – substances that stimulates and Site of maturation: bone marrow
triggers immune system - Before infecting the cells
TYPES OF ANTIBODIES: (immunoglobulin) – antibodies 1. Plasma B cells – secretes and release antibodies
2. Memory B cells – plasma B cell that activates
found inside the blood
pathogen
1. IgA – alpha
- Colostrum – breast milk
- respiratory and gastro intestinal
2. IgG – gamma
- activates phagocyte (macrophage and Additional (from quiz #2)
neutrophil) Gill System – gas exchange system present in fish and
3. IgM – mu marine life forms
- Activates B cell
4. IgD – delta Tracheoles – site of exchange of gases of various types
- Receptor of B cell of insects such as grasshopper
5. IgE – epsilon Cytokines – these are collective term for substances
- Activates allergy and inflammation that act as a signal to the immune system
TYPES OF ANTIGEN: Air Sacs – these allow air flight efficiency and
1. Exogenous – outside the body unidirectional airflow for birds
2. Endogenous – inside the body Immunity – state of resistance of an organism against
3. Autoantigen – stimulates auto immune pathogens
response ; ex. HIV
Infection – successful invasion of pathogens inside
MECHANISM OF ANTIBODY one’s body
1. Neutralization – preventing pathogens to bind Hydrochloric Acid – component of gastric juice that will
with your cell activate pepsinogen
2. Opsonization – tags and marks
3. Complement Activation – activating your Natural Killer Cells – cells that injects perforin and
complement system employs apoptosis
II. CELL MEDIATED RESPONSE Heparin - chemical substance which prevents blood
clotting in vessels
A. T-cells – infected cell
Originate: bone marrow B cells – lymphocytes that are produced by the bone
Site of maturation: thymus gland marrow
1. CD4+ - helper T cells
Prostaglandin – substance that controls blood flow and 1. Herbivores – consume plant as food
blood clot formation 2. Carnivores – consume other flesh organism
3. Omnivores – consume both plant and animal
Renin – produced by kidneys which regulates blood
4. Detritivores – dependent w/ decaying matter
pressure
METHOD OF NUTRITION OF UNICELLULAR ORGANISMS
Eosinophil – a type of WBC which is responsible for
endoparasites 1. Phagocytosis – cell-eating ; consume
macromolecules
Macrophage – these WBCs are large and exhibits 2. Pinocytosis – cell-drinking ; consume
phagocytotic activities and an activated monocyte substances
Interferons – substance that interferes with the Endocytosis – collective term of phagocytosis and
presence of viruses pinocytosis
Antibodies – specialized proteins that tag and mark 3. Receptor – mediated endocytosis ; specific
pathogens for phagocytotic defense substances ; (specialized)
T cells – lymphocytes that are produced by the thymus - LDL – low density lipoprotein (cholesterol)
gland HUMAN DIGESTION
Neutrophil – WBCs that are known to be “one-time use 4 TYPES:
only” phagocytes
1. Ingestion
Opsonization – process of tagging of antibodies to be 2. Digestion
consumed by the macrophages and neutrophils 3. Absorption
Basophil – a type of WBC that is responsible for 4. Elimination
inflammation and ectoparasites - INGESTION – consumption of food
1. Oral Cavity
ANIMAL NUTRITION AND METABOLISM - tongue
- teeth
Nutrition – process of intaking and converting food into - gums
functional unit
a. Mechanical digestion – called as “mastication”
Metabolism – different reactions inside a living
organism b. Chemical Digestion
2 TYPES OF ORGANISMS ACCORDING TO NUTRITION: - salivary amylase - enzyme that softens food
1. Autotrophs – can synthesize food by - mucin – protein inside the salivary amylase
themselves → oral cavity → pharynx – separates air & food →
Ex. plant through photosynthesis (CO2, H2O, sunlight) esophagus
2. Heterotrophs – only feeds on other organisms *bolus – food na nasstuck o dumadaan sa esophagus
*inside the stomach – 1. Parietal cells – produce HCL Ingestion Oral cavity to esophagus
Digestion Stomach to pyloric sphincter
2. Chief cells – produce
Absorption Small to large intestine
pepsinogen → pepsin Elimination Rectum to anus
*Pepsin – active form of pepsinogen
5. Pyloric sphincter – connection of stomach to small a. Water – a natural solvent that helps your body
intestine digest and eliminate wastes
8. Large intestine – absorbs excess water and minerals a. Sucrose – glucose + fructose
B. WATER SOLUBLE
HUMAN EXCRETION
a. Vitamin B1 - thiamine
b. Vitamin B2 - riboflavin
c. Vitamin B3 - niacin
Contractile vacuoles – vacuoles that are specialized for 4. Lungs – CO, water droplets
excretion
5. Liver – urea in the form of ammonia
2. Hydra/Sponge – diffusion (“spread”) (process) - nitrogen – proceeds to liver then will be
- multicellular converted to ammonia
5. Oliguria – low amount of urine less than 500 mL but a. Triiodothyronine (T3) – pag naactivate thyroxine
greater than 100 mL b. Thyroxine (T4) – inactive form gland
- nakakaihi pero sobrang onti
4. Parathyroid Gland
6. Anuria – low amount of urine less than 100 mL
Location: in the neck, behind the thyroid gland
*a = not/no
Hormones:
7. Nocturia/Nycturia – frequent urination during night
a. parathyroid hormone – regulates calcium and
phosphate
ENDOCRINE SYSTEM GLANDS (report) Calcitonin – one responsible to increase calcium and
1. Hypothalamus – master of the master gland phosphate absorption
Main function: homeostasis – balance of the body itself Calciferol – decreases calcium and phosphate
absorption
2. Adrenal Gland – also known as “master gland”
5. Pineal Gland – pineal from the word “pine” meaning
Hormones: cone-shaped
a. Adrenocorticotrophic – stimulates Location: behind the third cerebral ventricle
adrenal gland
b. Thyroid – stimulating Hormones:
hormone/stimulates thyroid gland a. melatonin – sleep wake
b. vasopressin
c. aldosterone – salt regulation 4. blood cell production
6. Pancreas – shared by digestive and endocrine system 5. calcium and phosphorus storage
Hormones: b. Divisions
a. insulin – decrease blood sugar 1. axial – bones that are for protection
ex. skull, rib cage, pelvic, spinal column
b. glucagon – increase blood sugar
2. appendicular – mobility
7. Adrenal Gland
ex. femur, patella, olecranon
Hormones:
c. Bone Shapes
a. cortisol – stress hormone ; metabolism changes
1. long bones – ex. femur, humerus, ulna, radius
b. aldosterone – salt regulation (Na & K)
2. short bones – ex. phalanges
c. adrenaline – stimulates reflex response
3. irregular bones – ex. carpals, tarsals
8. Thymus Gland
4. flat bones – ex. sternum
Location: sternum
5. sesamoid bones – ex. patella, olecranon
Hormone:
d. Structure of the bone
a. Thymosin – development of T-cells
- adaptive immune response Diaphysis – body of the bone
9. Ovary Gland
Hormones:
1. Fixed joints – immovable joints Production – to produce offspring for survival of species
b. hinge joint – found in elbows and knees *Mitosis = same characteristics of offspring
- bend, straighten
I. SEXUAL REPRODUCTION
c. pivot – found in skull
1. Gametogenesis – formation of gametes/sex cells
- side, up, down
2 methods:
d. gliding – sliding
ex. tarsal, carpal a. Spermatogenesis – formation of sperms
e. saddle – rotation, bend, straight *spermatogonium– stem cell inside the testes
ex. thumb
(stem cell: sperm cell)
ootid
DEVELOPMENTAL EMBRYOLOGY
ACCESSORY GLANDS:
ex. bee