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Antibiotic
Part 2

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Overview
Aminoglycosides 01
Penicillins 02
Cephalosporins 03
Macrolides 04
Tetracyclines 05
Fluoroquinolones 06
Sulfonamides 07
Oxazolidinones 08
Carbapenems 09
Glycopeptides 10
Polypeptides 11
Clindamycin 12
 Oxazolidinones

Oxazolidinones are a class of antibiotics used to treat serious infections,

often after other antibiotics have been ineffective.
Oxazolidinones include the following: Linezolid, and Tedizolid.

They are active against Serious infections caused by susceptible gram-

positive bacteria such as Staphylococcus, MRSA, Streptococcus, and
enterococci (including VRSA) that are resistant to many other antibiotics
 Oxazolidinones
01 02 03

MOA Dosing Most commonly used in

Inhibit bacterial protein Linezolid: 600 mg Skin and soft tissue

synthesis. twice daily. infections.
 Carbapenems

Carbapenems are a subclass of antibiotics called beta-lactam antibiotics

(antibiotics that have a chemical structure called a beta-lactam ring).

Carbapenems are broad-spectrum antibiotics. That is, they are effective

against many types of bacteria, including bacteria that are resistant to
many other antibiotics.
Carbapenems include the following: Doripenem, Ertapenem, Imipenem,
and Meropenem
 Carbapenems
01 02 03

MOA Dosing Most commonly used in

Inhibit bacterial cell Meropenem: 1 g Serious infections,

wall synthesis. every 8 hours. including hospital-acquired
pneumonia.
 Glycopeptides

Glycopeptides and lipoglycopeptides are antibiotics used to treat

complicated and/or serious infections caused by gram-positive bacteria.

Glycopeptides and lipoglycopeptides include the following: Dalbavancin,

Teicoplanin, Telavancin, and Vancomycin
 Glycopeptides
01 02 03

MOA Dosing Most commonly used in

Inhibit bacterial cell Vancomycin: 15-20 Serious infections

wall synthesis. mg/kg every 8-12 caused by resistant
hours. organisms.
 Polypeptides

Polypeptides are a class of antibiotics used to treat several types of

infections.

Polypeptides include the following: Bacitracin, Colistin, and Polymyxin B

Bacitracin is used mainly to treat superficial skin infections caused by

Staph aureus, and bladder infections (polymyxin B may be used for bladder
irrigation)
 Polypeptides
01 02 03

MOA Dosing Most commonly used in

Works by Colistin: IV dosing Reserved for the

preventing bacteria often ranges from treatment of severe
from forming this 2.5-5 mg/kg every infections caused by
wall. 12 hours. multidrug-resistant
Gram-negative bacteria
 Clindamycin

Clindamycin belongs to a class of antibiotics called lincosamides.

Clindamycin is used to treat serious bacterial infections, including some
infections that are resistant to other antibiotics.

Active against Streptococcal infections and staphylococcal infections,

Respiratory infections, Lung abscess.
 Clindamycin
01 02 03

MOA Dosing Most commonly used in

Clindamycin Oral doses range Skin and soft tissue

inhibits bacterial from 150-300 mg infections, respiratory
protein synthesis every 6 hours, tract infections, bone
and joint infections.
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