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Drug of ChoicePart No. 1

Choosing the most suitable medicine

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Hypertension (High blood
pressure)

Drug of choice: Thiazide-type diuretics

Dosing: The usual dose is 12.5 mg given

alone or in combination with other
antihypertensives, with a maximum dose of
50 mg daily.
Major Depressive Disorder

Drug of choice: Sertraline

Dosing: Initial dose of 50 mg once daily,

which may be increased at weekly
intervals according to response up to a
maximum of 200 mg per day.
Type 2 Diabetes
Mellitus
Drug of choice: Metformin

Dosing: Start with 500 mg orally

once a day, with gradual increase
up to 2000 mg per day in divided
doses.
Asthma (acute exacerbation)

Drug of choice: Albuterol (Salbutamol)

inhaler.

Dosing: 2 puffs every 4 to 6 hours as

needed.
Hypercholesterolemia

Drug of choice: Atorvastatin

Dosing: 10-20 mg once daily; some

patients may require 40-80 mg
once daily.
Gastroesophageal Reflux
Disease (GERD)
Drug of choice: Omeprazole.

Dosing: 20 mg once daily before a

meal for 4-8 weeks.
 Rheumatoid Arthritis
Drug of choice: Methotrexate.

Dosing: Start with 7.5 mg once weekly, which may be

increased gradually to a usual maximum of 25 mg per week.
Chronic Obstructive Pulmonary Disease
(COPD) Exacerbation
Drug of choice: Albuterol (short-
acting beta-agonist)

Dose: 2.5-5 mg via nebulizer every

20 minutes for 3 doses, then as
needed.
Edema associated with
congestive heart failure

Drug of choice: Furosemide

Dose: 20 to 80 mg per day, with

subsequent doses being adjusted
based on response.
Epilepsy

Drug of choice: Valproate sodium

Dose: 10-15 mg/kg/day PO initially;

increase by 5-10 mg/kg/day at weekly
intervals; may increase dose up to 60
mg/kg/day
 Thank You
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