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URDANETA CITY
UNIVERSITY College of Pharmacy
Owned and operated by the City Government of Urdaneta

UNIT 6. TRANSDERMAL DRUG DELIVERY SYSTEM AND TECHNOLOGIES

LEARNING OBJECTIVES:
At the end of this module, the students should be able to:
• Differentiating the various types of systems used for transdermal delivery
• Discussing the advantages and disadvantages of transdermal delivery of drugs compared to other forms of
drug delivery.
• Providing examples of drugs which are delivered transdermally and list precautions associated with their
use.
• Describing tapes as a topical drug delivery system
• Discussing new approach in Differentiating the various types of systems used for transdermal delivery
• Discussing the advantages and disadvantages of transdermal delivery of drugs compared to other forms of
drug delivery.
• Providing examples of drugs which are delivered transdermally and list precautions associated with their
use.
• Describing tapes as a topical drug delivery system
• Discussing new approach in TDDS

TOPIC OUTLINE:
1. Design features of TDDS
2. Advantages and Disadvantages of TDDS
3. Examples of TDDS
4. Tapes
5. New Approach

Transdermal Drug Delivery Systems

➢ Controlled release DDS or patches that allow the passage of drugs from the skin to the systemic
circulation
➢ facilitate the passage of therapeutic quantities of drug substances through the skin and into the general
circulation for their systemic effects.

Advantages and Disadvantages

ADVANTAGES DISADVANTAGES

Parts of Transdermal Drug Delivery System

This document is not for sale and is solely for educational purposes of UCU pharmacy students only. Reproduction, distribution,
uploading or posting online, transmitting in forms of any part of this document without prior permission is strictly prohibited.

DRUG DELIVERY SYSTEMS LECTURE |

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URDANETA CITY
UNIVERSITY College of Pharmacy
Owned and operated by the City Government of Urdaneta

Parts of Transdermal Drug Delivery System

1. Occlusive Backing Film
-

2. Drug Matrix System/ Drug Reservoir

-

3. Controlled Membrane
-

4. Adhesive Layer
-

5. Release Liner
-

Examples of TDDS
❑ Scopolamine (Transderm Scop®)
❑ TD Nicotine

❑ TD Nitroglycerin
❑ TD Estradiol

❑ TD Clonidine

❑ TD Testosterone
❑ TD Fentanyl ➢ Androderm
➢ Testoderm

This document is not for sale and is solely for educational purposes of UCU pharmacy students only. Reproduction, distribution,
uploading or posting online, transmitting in forms of any part of this document without prior permission is strictly prohibited.

DRUG DELIVERY SYSTEMS LECTURE |

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URDANETA CITY
UNIVERSITY College of Pharmacy
Owned and operated by the City Government of Urdaneta

Tapes
➢ dosage form that is suitable for delivering drugs to the skin.
➢ It consists of a drug that is impregnated into a flexible, durable woven fabric or extruded synthetic
material that is coated with an adhesive agent.
➢ For administration, a portion of the tape slightly larger than the area to be treated is cut and removed
from the backing paper.
➢ It should not be applied to folds in the skin but rather to a smooth skin surface.
➢ It should be applied to dry skin.

Compiled by:

Princess Angelica M. Pamogas, RPh

Instructor, College of Pharmacy

This document is not for sale and is solely for educational purposes of UCU pharmacy students only. Reproduction, distribution,
uploading or posting online, transmitting in forms of any part of this document without prior permission is strictly prohibited.

DRUG DELIVERY SYSTEMS LECTURE |