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Correspondence

2 Lee R. Mortality forecasts and linear life I declare no competing interests. model in future iterations. We are,
expectancy trends. In: Bengtsson T, Keilman N,
eds. Old and new perspectives on mortality Nico Keilman however, reluctant to base policy
forecasting. Demographic research nico.keilman@econ.uio.no scenarios on covariates with an
monographs (a series of the Max Planck uncertain foundation for a causal
Institute for Demographic Research). Department of Economics, University of Oslo,
Dordrecht: Springer, 2019: 167–83. N 0951 Oslo, Norway effect.
1 Vollset SE, Goren E, Yuan C-W, et al. Fertility, Jane N O’Sullivan is critical of our
New population forecasts by mortality, migration, and population scenarios projections and claims that we are
for 195 countries and territories from
Stein Vollset and colleagues1 predict 2017 to 2100: a forecasting analysis for the
undermining population control
lower global population growth than Global Burden of Disease Study. Lancet 2020; policies and women’s reproductive
do other forecasts—for instance, the 396: 1285–306. rights. We do not agree. We explicitly
2 UN Department of Economic and Social
one published by the UN.2 Vollset Affairs Population Division. World stated how important it is to protect
and colleagues assume relatively low population prospects 2019, vol I: women’s reproductive rights in our
comprehensive tables. New York, NY:
fertility in the future compared with United Nations, 2019.
Article. Pretending that decreases in
UN and other forecasts, which leads to 3 Psaki SR, Soler-Hampejsek E, Saha J, fertility do not exist does not solve
low population growth. Mensch BS, Amin S. The effect of adolescent the problem of overpopulation. As
childbearing on literacy and numeracy in
I believe that fertility is not Bangladesh, Malawi, and Zambia. Demography an example of where our estimates
adequately modelled in the new 2019; 56: 1899–929. fail, she points to the acceleration of
forecasts. Vollset and colleagues 4 Cohen JE, Kravdal Ø, Keilman N. Childbearing fertility decline that our estimates
impeded education more than education
assume that the educational level impeded childbearing among Norwegian show from around 2006. Her
of women is an important driver for women. Proc Natl Acad Sci U S A 2011; claim that our fertility trend for
108: 11830–35.
future fertility levels. Indeed, highly 5 Gerster M, Ejrnæs M, Keiding N. The causal
sub-Saharan Africa deviated from the
educated women tend to have fewer effect of educational attainment on completed estimates from the UN is incorrect.
children than do women with little fertility for a cohort of Danish women: UN 4 estimates showed a similar
does feedback play a role? Stat Biosci 2014;
or no education, both in low-income 6: 204–22. slope to ours, and the UN values are
and high-income countries. However, closer to ours than those from the
not only does education affect Authors’ reply Population Reference Bureau. We
fertility but also the reverse is true: We appreciate the opportunity to have redrawn O’Sullivan’s figure from
fertility influences school attendance. respond to comments regarding our the appendix with the addition of the
Adolescent girls and young women Article.1 2019 estimates from the UN World

Pascal Deloche/Godong/Universal Images Group/


(ie, aged approximately 15–25 years) Nanna Maaløe and colleagues Population Prospects (appendix).
with one or more children have suggest that we should use child Furthermore, O’Sullivan finds
fewer opportunities to attend school survival as a covariate in our fertility our calculation of countries’ gross
than do women without children, model. The hypothesis that child domestic product (GDP) from
as shown by studies in Bangladesh, mortality is a predictor of fertility forecasts of GDP per worker and
Malawi, and Zambia,3 Norway,4 and rates has been debated in the field of future working-age populations

Getty Images
Denmark.5 demography for some time. Although concerning. Our approach is based
A model that includes a two-way there is evidence that a relationship on out-of-sample predictive validity
association between fertility and exists between child mortality and evidence that GDP is more accurately For more on the Population
education will predict higher fertility fertility rates, the causal pattern estimated from growth rates for Reference Bureau datasheets
see https://www.prb.org/
levels in countries where women have between these two measures is GDP per worker than from GDP per datasheets
little education, compared with the not well established.2 We modelled capita.5 We are aware that limitations See Online for appendix
model that was used by Vollset and fertility with female educational with this approach include the
colleagues. Little schooling leads to attainment and contraceptive met potential for future compensatory
high fertility, which, in turn, causes need as covariates. These covariates mechanisms to protect GDP under
decreased education. At the same are well established as major declining working-age populations: for
time, fertility levels will be lower predictors of fertility,3 and together example, increasing female workforce
in countries where women have a they explained a large proportion of participation, delaying retirement,
lot of schooling when the two-way the past variance in fertility. When and increasing automation of major
association is modelled compared with we added survival rates for children economic sectors.
the unidirectional model of Vollset younger than 5 years to the model, Stuart Gietel-Basten and
and colleagues. I suspect that the new the explained variance increased Tomas Sobotka are concerned that
forecasts predict too few births in low- modestly, from 80·5% to 83·1%. our models, data, and underlying
income countries and particularly in We appreciate the feedback and will assumptions have not received
sub-Saharan African countries. continue to improve our fertility enough scrutiny. As with the Global

www.thelancet.com Vol 398 August 14, 2021 581


Correspondence

Burden of Diseases, Injuries, and Zambia.10–12 Our current framework 12 Psaki SR, Soler-Hampejsek E, Saha J,
Mensch BS, Amin S. The effects of adolescent
Risk Factors Study, our approach is and data do not allow for assessing childbearing on literacy and numeracy in
a systematic scientific effort that this hypothesis. We appreciate Bangladesh, Malawi, and Zambia. Demography
attempts to include all relevant the comment, however, and will 2019; 56: 1899–929.

available data. The data and models consider it in future iterations of our
are transparent, peer-reviewed, and population forecasts.
follow the Guidelines for Accurate We declare no competing interests. This project was
and Transparent Health Estimates funded by the Bill & Melinda Gates Foundation.
The funder had no role in the development of this
Reporting.6 Correspondence.
They also claim that our fertility
model is based on uncertain future Stein Emil Vollset, Amanda E Smith,
pathways. Of course, all long-term Catherine Bisignano,
predictions are, but education *Christopher J L Murray
cjlm@uw.edu
trajec­t ories are well determined
because educational attainment is Institute for Health Metrics and Evaluation,
University of Washington, Seattle, WA 98195, USA
known after age 25 years. Further,
1 Vollset SE, Goren E, Yuan C-W, et al. Fertility,
they claim that our models are mortality, migration, and population scenarios
simplistic. There might be nuances for 195 countries and territories from
2017 to 2100: a forecasting analysis for the
to cultural decisions about having Global Burden of Disease Study. Lancet 2020;
children, but our fertility model with 396: 1285–306.
female educational attainment and 2 Doepke M. Child mortality and fertility decline:
does the Barro-Becker model fit the facts?
contraceptive met need explains J Popul Econ 2005; 18: 337–66.
80·5% of past variation in fertility. 3 Götmark F, Andersson M. Human fertility in
The UN model, by contrast, uses only relation to education, economy, religion,
contraception, and family planning programs.
time as a determinant of women’s BMC Public Health 2020; 20: 265.
reproductive choice. 4 UN Department of Economic and Social
Affairs Population Division. World
Finally, Gietel-Basten and Sobotka population prospects 2019, vol I:
claim that our mortality forecasts comprehensive tables. New York, NY:
are overly pessimistic. Mortality has United Nations, 2019. Department of Error
5 Chang AY, Cowling K, Micah AE, et al.
almost no effect on population, and Past, present, and future of global health Hyde R. The slow road to atonement. Lancet
in fact, a slow down or stagnation financing: a review of development 2021; 398: 105–08—In this World Report, the
assistance, government, out-of-pocket, media, not experts, speculated that the
Published Online in life-expectancy growth have and other private spending on health for remains found came from Auschwitz.
August 5, 2021 been observed in many countries 195 countries, 1995–2050. Lancet 2019; The police were aware of the remains, but they
https://doi.org/10.1016/ 393: 2233–60.
S0140-6736(21)01746-3 in the past decade. 7–9 Given the were not briefed on their potential historical
6 Stevens GA, Alkema L, Black RE, et al. significance. Camp inmates were subjected to
obesity epidemic and other adverse Guidelines for Accurate and Transparent extreme cold and lack of oxygen by Nazis,
trends in risk factors, we might, in Health Estimates Reporting: the GATHER but not by Josef Mengele. Membership of the
statement. Lancet 2016; 388: e19–23.
many instances, have been overly Nazi party was encouraged but not compulsory
7 Lopez AD, Adair T. Slower increase in life for all physicians. Physicians’ organisations
optimistic in our forecasts of expectancy in Australia than in other high were drastically reconfigured, not shut down
mortality. income countries: the contributions of age entirely. The hospital wards were not set up
and cause of death. Med J Aust 2019;
Nico Keilman suggests that we 210: 403–09.
with the explicit aim of murdering Jews,
although Jews were killed. Sewering was
are underestimating fertility in sub- 8 Woolf SH, Schoomaker H. Life expectancy and
President-elect of the World Medical
Saharan Africa. His argument is mortality rates in the United States,
1959–2017. JAMA 2019; 322: 1996–2016. Association, but did not become President.
that the causal pathway between 9 Leon DA, Jdanov DA, Shkolnikov VM. Trends in
Spelling errors have been corrected. These
education and fertility is bidirectional life expectancy and age-specific mortality in corrections have been made to the online
England and Wales, 1970–2016, in comparison version as of Aug 5, 2021.
and should be modelled as such with a set of 22 high-income countries:
to avoid bias, possibly in the Borobia AM, Carcas AJ, Pérez-Olmeda M, et al.
an analysis of vital statistics data.
Lancet Public Health 2019; 4: e575–82. Immunogenicity and reactogenicity of
opposite direction in settings with BNT162b2 booster in ChAdOx1-S-primed
10 Cohen JE, Kravdal Ø, Keilman N. Childbearing
high and low education among impeded education more than education participants (CombiVacS): a multicentre, open-
women. The hypothesis is based on impeded childbearing among Norwegian label, randomised, controlled, phase 2 trial.
women. Proc Natl Acad Sci USA 2011; Lancet 2021; 398: 121–30—For this Article,
studies of education and fertility 108: 11830–35. Judit Riera-Arnau’s name was misspelt.
in birth cohorts of Norwegian 11 Gerster M, Ejrnæs M, Keiding N. The causal The CombiVacS Study Group list and the
and Danish women, plus a study effect of educational attainment on completed appendix have been updated. This correction
fertility for a cohort of Danish women— has been made to the online version as of
on the effect of childbearing on does feedback play a role? Stat Biosci 2014; Aug 12, 2021.
literacy in Bangladesh, Malawi, and 6: 204–22.

582 www.thelancet.com Vol 398 August 14, 2021

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