1. All of the following features except one are seen in Henoch-Schonlein purpura.

Which is the exception?

A. Arthralgia
B. Glomerulonephritis
C. Raised serum IgA
D. Thrombocytopenia
ANSWER: D

2. Which of the following is least likely to be associated with gout?

A. Thiazide diuretics
B. Rheumatoid arthritis
C. Low dose aspirin
D. Osteoarthritis
ANSWER: B

3. All of the following except one are joints frequently involved in ankylosing
spondylitis. Which is the exception?
A. Small joints of hands
B. Sacroiliac joints
C. Spine
D. Hip joints
ANSWER: A

4. Which of the following is the commonest cardiac lesion in rheumatoid arthritis?

A. Pancarditis
B. Pericarditis
C. Myocarditis
D. Endocarditis
ANSWER: B

5. In a patient with gouty arthritis, which of the following is most useful in

establishing the diagnosis?
A. Serum uric acid
B. Uric acid in urine
C. Urate crystal in synovial fluid
D. Serum calcium level
ANSWER: C

6. Which one of the following statements is correct about ankylosing spondylitis?

A. Peripheral joint is rarely involved
B. Sacroiliac joints are usually spared
C. May be associated with anterior uveitis
D. More common in females
ANSWER: C

7. All of the following statements except one are correct about gout. Which is the
exception?
A. Occurs due to accumulation of urate crystals in joint
B. Can be precipitated by pyrazinamide
C. Occurs more frequently in females
D. Hyperuricemia in primary gout is mainly due to decreased excretion of uric acid
ANSWER: C

8. Which one of the following is least likely to occur as a part of seropositive

rheumatoid arthritis?
A. Splenomegaly
B. Pericarditis
C. Pleural effusion
D. Hepatomegaly
ANSWER: D

9. Pseudogout can be distinguished from gout by means of:

A. Acute onset
B. Positive birefringent crystals
C. Association with diabetes mellitus
D. Involvement of large joints
ANSWER: B

10. Which of the following joints is characteristically involved in rheumatoid

arthritis?
A. Spine
B. Knee joint
C. Metacarpophalangeal joint
D. Distal interphalangeal joint
ANSWER: C

11. Pseudogout has been associated with or encountered in:

A. Hypomagnesemia
B. Hemochromatosis
C. Hyperparathyroidism
D. All of the above
ANSWER: D

12. Which of the following is true of psoriatic arthritis?

A. Involves distal joints of hand
B. Pencil-in-cup deformity may be seen
C. Sacroiliitis may be seen
D. All are correct
ANSWER: D

13. Which of the following joints is most frequently involved in a patient with an
acute attack of gout?
A. Knee joint
B. Ankle joint
C. 1st metatarsophalangeal joint
D. 1st metacarpophalangeal joint
ANSWER: C

14. All of the following except one are features of rheumatoid arthritis. Which is
the exception?
A. Anti IgG antibody
B. Antinuclear antibody
C. Early morning stiffness
D. No joint deformity
ANSWER: D

15. Rheumatoid arthritis commonly affects which one of the following regions of the
spine?
A. Cervical spine
B. Lumbar spine
C. Thoracic spine
D. Sacral spine
ANSWER: A

16. Prolonged allopurinol therapy in a patient with gout is indicated in all except
one of the following conditions. Which is the exception?
A. Acute gouty arthritis
B. Tophi
C. Urate nephropathy
D. Evidence of bone /joint damage
ANSWER: A

17. Which of the following is true regarding rheumatoid arthritis?

A. Typically spares the cervical spine
B. Causes pleural effusion with low sugar
C. Pulmonary nodules are absent
D. Enthesitis is prominent
ANSWER: B

18. All of the following except one are characteristic features of ankylosing
spondylitis. Which is the exception?
A. Strongly positive rheumatoid factor
B. Association with HLA-B27
C. Anterior uveitis
D. ‘Bamboo’ spine on X-ray
ANSWER: A

19. All of the following except one can be used to prevent attacks of gouty
arthritis. Which is the exception?
A. Allopurinol
B. Aspirin
C. Probenecid
D. Febuxostat
ANSWER: B

20. As per the current recommendations, the first line of treatment for ankylosing
spondylitis is:
A. NSAIDs
B. Golimumab
C. Etanercept
D. Infliximab
ANSWER: A

21. Which one of the following features is not seen in reactive arthritis?
A. Subcutaneous nodules
B. Keratoderma blennorrhagicum
C. Circinate balanitis
D. Sausage digit
ANSWER: A

22. Which one of the following is a characteristic feature of Reiter’s disease?

A. Conjunctivitis
B. Subcutaneous nodules
C. Precipitated by streptococcal throat infection
D. Positive rheumatoid factor
ANSWER: A

23. All of the following conditions except one are frequently observed in gout.
Which is the exception?
A. Uric acid nephrolithiasis
B. Deficiency of enzyme xanthine oxidase
C. Hyperuricemia
D. Renal disease involving interstitial tissues
ANSWER: B

24. The crystals isolated from joint in a patient with pseudogout consist of:
A. Calcium pyrophosphate
B. Sodium urate
C. Potassium urate
D. Sodium pyrophosphate
ANSWER: A

25. Which of the following is the most common clinically apparent cardiac
manifestation of systemic lupus erythematosus?
A. Myocarditis
B. Libman-Sacks endocarditis
C. Pericarditis
D. Aortic regurgitation
ANSWER: C

26. All of the following except one are typical clinical features of scleroderma.
Which is the exception?
A. Dysphagia
B. Raynaud's phenomenon
C. Skin contracture
D. Malar rash
ANSWER: D

27. Which of the following is least likely to be seen as a manifestation of SLE?

A. Pterygium
B. Alopecia
C. Anemia
D. Arthritis
ANSWER: A

28. All of the following except one are typical clinical features of scleroderma.
Which is the exception?
A. Pulmonary fibrosis
B. Esophageal dysmotility
C. Resorption of terminal phalanges
D. Lung nodules
ANSWER: D

29. All of the following except one are clinical features of systemic lupus
erythematosus. Which is the exception?
A. Recurrent abortion
B. Sterility
C. Coombs' positive hemolytic anemia
D. Psychosis
ANSWER: B

30. Which one of the following antibodies is most useful in diagnosing Sjögren’s
syndrome?
A. Anti SS-A
B. Anti SCL-70
C. Anti-centromere
D. Anti-histone
ANSWER: A