MYASTHENIA GRAVIS

muscr Tansmsionv
PEEY SiGN
DioeNAL VARIATION Syntms
* Motur wealnes, DTR (N)
* rost Synatic memiare t Blonti
CuRTAÍN SiCN weane Clled

Myaestheni
 Aso entlains de«ementall Rest Onoe
Seen on EDx RNS
study
Anti Ach R Ab Tedu ceb the tumbr d avaliabo
Ach & ot NNIby 3 dishint machanis

2- Damage To bost synoti menbiane(comylend

msdiatad)
3 Bock ade d Ahß at Achie sta
 Overview Signs and 5ynptoms
An autoimmAne disease that afferts the skeletal mascles Affect any oi the muscies that the patient controls voluntarily
- Facial mkstle weakness
Characterized by Weakness and rapid Fatigue
of any of the mscles wnder volantary control Proaping eyelits
The mascle weakness Pouble vision

Norse with activity Inproves with rest Pifficwity in breathing, Taiking

Che wing or Swallowing
Preferentially affects Muscle weakness in arms or ieqs

in their 20s and 52s over the aqe of loD Fatigwe cawsed by repetitive motions

Myasthenia Gravis
Treatment Causes Thånus

Acetylcholinesterase lnhibitor
lex Nzostignine or Pyritostignine) NOKMAL Myasthenia Gravis
Fewer rereptor sites
Azetgicholinesterast kegrates Acetjicholine
|Contentration of Atetycholine Araand mascle tells Nene
Fewer nerve signals
Counteract tht effe:ts of Acetylcholine rezeptor antibodies fatigwe, ilness,
Improve nastle tontrattion and mastie strength WEAKNE55 Stres
Extreme heat
AcevkkÃnc
Corticosteroids lex Preánisonel Surgical Kenoval Metications EX.
Inhibit the innAAe systen Linit antibody prodactin 0f The Thyms Aboamkvht
Protwced Dy Peta blackers
o AChk
"Proianged wse Bone thianing, Waight gain, Pabetes, Musde
kisk of somt infettions, Kedistribation of body fat X 5ohe antibio tics
Muckattals tied
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(Mayes fkernà Gravit

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