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    Benito O. de Lumen is an American science educator specializing in plant physiology and molecular biology. In his laboratory at the University of California Berkeley in 1997, a post-doctoral researcher discovered lunasin, a peptide from soy with anti-cancer properties. Lunasin was discovered as part of a project to enhance the nutritional value of soy and legumes by increasing their methionine content through bioengineering. De Lumen's decision to clone the methionine-rich gene from soy itself ultimately led to the discovery of lunasin's anti-cancer effects. He is recognized for this significant contribution and discovery, which has applications for natural product biochemistry, and he currently leads a company commercializing lunasin.

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    Excercise 4; DIRECTION

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    Benito O. de Lumen is an American science educator specializing in plant physiology and molecular biology. In his laboratory at the University of California Berkeley in 1997, a post-doctoral researcher discovered lunasin, a peptide from soy with anti-cancer properties. Lunasin was discovered as part of a project to enhance the nutritional value of soy and legumes by increasing their methionine content through bioengineering. De Lumen's decision to clone the methionine-rich gene from soy itself ultimately led to the discovery of lunasin's anti-cancer effects. He is recognized for this significant contribution and discovery, which has applications for natural product biochemistry, and he currently leads a company commercializing lunasin.

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    8 views1 page

    Excercise 4 DIRECTION

    Uploaded by

    robertvaliente471
    Benito O. de Lumen is an American science educator specializing in plant physiology and molecular biology. In his laboratory at the University of California Berkeley in 1997, a post-doctoral researcher discovered lunasin, a peptide from soy with anti-cancer properties. Lunasin was discovered as part of a project to enhance the nutritional value of soy and legumes by increasing their methionine content through bioengineering. De Lumen's decision to clone the methionine-rich gene from soy itself ultimately led to the discovery of lunasin's anti-cancer effects. He is recognized for this significant contribution and discovery, which has applications for natural product biochemistry, and he currently leads a company commercializing lunasin.

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    of 1

    A .

    Professional Background
    Benito O. de Lumen, is an American Science educator. He is a member of the
    American Association for the Advancement of Science, American Society Plant
    Physiologists, International Society Plant Molecular Biologists, American Institute
    Nutrition, Institute Food Technologists, Volunteers for International Technology
    Assistance. Lumen, Benito O. de was born on July 28, 1940 in Taytay, Philippines. Son
    of Amado S. and Soledad O. de Lumen. came to the United States, 1965.

    B.Area of Specialization
    Lunasin’s biological and cancer-preventive activity was discovered by a Filipino
    doctor during his post- doctoral research --- Dr. Alfredo Galvez in Dr. Benito de Lumen
    (another Filipino doctor) laboratory in the University of California – Berkeley in 1997.
    This is an excerpt from Dr. de Lumen’s statement on the discovery of Lunasin, “Many
    years ago, my laboratory initiated a project on enhancing the nutritional value of soy
    protein and other legumes through bioengineering. This requires increasing the level of
    methionine, the essential amino acid, which is most limiting in soy and other legumes,
    including mung bean. The strategy is quite straightforward: clone a gene coding for
    methionine-rich protein (MRP) and over- express the gene in soy or any target legume.
    We were faced with two choices for the source of the MRP gene – obtain it from
    other plants or from soy itself. I made the fateful decision to clone the MRP gene from
    soy itself, which eventually led to the discovery of lunasin as a cancer preventive agent.”

    C.Invention or Discovery
    Professor Benito O. Lumin. His most significant contribution is the discovery of
    lunasin, a cancer preventative from seeds of common crop plants. This discovery has
    led to important contributions to natural products of biochemistry. He was elected as a
    Fellow of the American Association for the Advancement in Science for this work and
    currently he is the Founder and CEO of Narra Biosciences, LLC, a biotech company
    commercializing the anti-cancer seed peptide lunasin

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