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A Review : Nanotechnology in Skin Cancer Treatment

Anish Pawar & Jaspreet Singh


Aakash Institute of Medical Sciences,Nalagarh Solan (H.P)
174101
dixitpawar84@gmail.com

INTRODUCTION TREATMENT
Cancer is a complex group of diseases characterized by the uncontrolled Gene Therapy:
growth and spread of abnormal cells. There are many types of cancer, and
they can affect various tissues and organs in the body. Cancer can develop Nanocarriers for Gene Delivery: Nanoparticles can serve as carriers
when the normal control mechanisms within cells break down, leading to for therapeutic genes, enabling targeted delivery to cancer cells. This
the formation of a mass or tumor. approach allows for the modulation of specific cellular functions, such
as apoptosis or immune response, to combat cancer.
Skin cancer is a type of cancer that originates in the skin cells. The skin is
the body's largest organ and serves as a protective barrier against external Immunotherapy Enhancement:
elements. Skin cancer occurs when the DNA in skin cells becomes
damaged, usually due to exposure to ultraviolet (UV) radiation from the Nanoparticle Vaccines: Nanoparticles can be engineered to mimic
sun or tanning beds. This damage can lead to uncontrolled cell growth and antigens, boosting the immune response against cancer cells.
the formation of malignant tumors. Additionally, they can carry immunomodulatory agents to enhance the
effectiveness of immunotherapy.
Nanotechnology, the manipulation of matter on an atomic and
molecular scale, has shown vast potential for revolutionizing
disease diagnosis, treatment, and prevention

TYPES OF SKIN CANCER


There are three main types of skin cancer:

Basal Cell Carcinoma (BCC): This is the most common type of skin
cancer. It usually appears on areas of the skin that are frequently exposed to
the sun, such as the face and neck. BCC typically grows slowly and rarely
spreads to other parts of the body.

Squamous Cell Carcinoma (SCC): SCC is the second most common type
of skin cancer. It tends to occur on areas exposed to the sun but can also RESULT
develop in scars, chronic skin sores, or areas of radiation exposure.
The field of nanotechnology in skin cancer treatment is still evolving,
ongoing research and clinical trials show promising results, indicating the
Melanoma: Although less common than BCC and SCC, melanoma is the
most dangerous type of skin cancer. It can develop in any part of the body, potential for transformative breakthroughs in the near future.
not just areas exposed to the sun
Nanotechnological advancements offer innovative and targeted approaches
.. that can significantly improve the efficacy and specificity of skin cancer
treatments. Nanoparticles, such as liposomes, dendrimers, and gold
nanoparticles, enable precise drug delivery to cancer cells while
minimizing damage to healthy tissues.

CONCLUSION
In conclusion, the application of nanotechnology in the treatment of skin
cancer holds great promise for revolutionizing the field of dermatology and
oncology.
Moreover, the development of nanoscale imaging techniques enhances
RISK FACTORS OF SKIN CANCER early detection and monitoring of skin cancer, providing clinicians with
valuable insights for timely intervention.
Risk factors for skin cancer include:

UV Exposure: Prolonged exposure to UV radiation from the sun or REFERENCES


tanning beds is a major risk factor.  Kao, S.Y.Z.; Ekwueme, D.U.; Holman, D.M.; Rim, S.H.; Thomas,
C.C.; Saraiya, M. Economic burden of skin cancer treatment in the
Fair Skin: People with fair skin, light hair, and blue or green eyes are at a USA: An analysis of the Medical Expenditure Panel Survey Data,
higher risk. 2012–2018. Cancer Causes Control 2023, 34, 205–212.

Family History: A family history of skin cancer may increase the  Sun, H.; Li, Y.; Zeng, F.; Meng, Y.; Du, S.; Deng, G. Melanoma
likelihood of developing the disease. survivors are at increased risk for second primary keratinocyte
carcinoma. Int. J. Dermatol. 2022, 61, 1397–1404
Contact
Weakened
<your name> Immune System: Individuals with weakened immune
References
<your
systemsorganization>
are more susceptible.  Diaz, M.J.; Mark, I.; Rodriguez, D.; Gelman, B.; Tran, J.T.;
Email: Kleinberg, G.; Levin, A.; Beneke, A.; Root, K.T.; Tran, A.X.V.; et al.
Website:
Previous Skin Cancer: Having had skin cancer before increases the Melanoma Brain Metastases: A Systematic Review of Opportunities
Phone: for Earlier Detection, Diagnosis, and Treatment. Life 2023, 13, 828.
risk of developing it again.

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