LIAQUAT UNIVERSITY OF MEDICAL AND HEALTH SCIENCES JAMSHORO 1ST PROFESSIONAL

MBBS, MODULE TEST 2022

MODULE TEST
Date: 03-08-2022 Single best Type MCQs
Maximum Marks: 150 Time Allowed: 2 Hours Seat No:
FOUNDATION MODULE
8. A 40 year old male presented to feeling severe pain while
turning his neck. his physician realize that the problems is in
1. ANATOMY his pivot joint. Which of the following joint is been examined?
A body is divided into two equal anterior and posterior halves a. Atlantooccipital joint
by which of the following imaginary planes: b. Atlantoaxial joint
a. Para-median Plane c. Carpometacarpal joint
b. Right Median plane d. Proximal tibiofi bular joint
c. Left median plane e. Intervertebral disks
d. Mid sagital plane
e. Coronal Plane 9. A 50- years old women presented to physician with a tear in
the fibrous sheets that are located under the skin and cover
2. A carpenter is hammering the head of a nail. Which of the
the muscles. Which of the following structures would most
following movement is responsible for generating force in the
likely be affected?
hammer?
a. Tendon
a. Flexion of shoulder
b. Synovial tendon sheath
b. Extension of wrist
c. Aponeurosis
c. Flexion of wrist
d. Fascia
d. Extension of Elbow
e. Ligament
e. Flexion of Elbow
10. Which of the following cellular modification association with
3. The muscle that helps the prime mover by preventing the
epithelia, which provides a morphological barrier between
undesired actions at the proximal joints is called:
adjacent cells.
a. Agonist
a. Glycocalyx
b. Synergistic
b. Macula densa
c. Fixator
c. Zonula adherens
d. Antagonist
d. Nexus
e. Opponent
e. Zona occuldens
4. A 44 years-old man was diagnosed by the neurologist as
suffering from demyelination of peripheral nervous system. 11. In a histology laboratory, laboratory technician was
Which of the following cells are likely affected in this patient? examining the slides of different cells of connective tissue on
a. Motor Neurons microscope. He saw a cell having cart-wheel appearance of its
b. Sensory Neurons nucleus which is the characteristic feature of following cell?
c. Schwann Cells a. Mast Cell
d. Neuroglial cells b. Adipocyte
e. Astrocytes c. Plasma cell
5. A 26 years old man received a wound, and axons of the motor d. Eosinophil
neurons to the shoulder muscles were severed. the damaged e. Fibroblast
axons:
a. Carry impulses toward the cell bodies 12. A girl came to dermatologist with complain of excessive acne
b. Carry Impulses away from the cell bodies on her face involving the sebaceous gland of skin. This
c. Carry pain impulses affected gland is histologically the type of following gland?
d. Are several in numbers for multipolar neurons a. Simple acinar gland
e. Are found primarily in the gray matter b. Branched acinar gland
c. Simple branched acinar gland
6. After general physical examination, the physician informs his d. Compound branched tubular gland
patient that his parasympathetic nerves are damaged. Which of e. Simple tubular gland
the following muscles must likely is affected?
a. Muscles in the hair follicles 13. Laboratory technician was preparing the slides of blood cells
b. Muscles in blood Vessels for light microscopy in which he was performing fixation by
c. Muscles that act at the elbow joint which of the following fixative?
d. Muscles in the gastrointestinal tract a. Glutaraldehyde
e. Muscles enclosed by epimysium b. Alcohol
7. Boy fell on the ground while riding the bicycle and his scaphoid c. Formalin
bone (Carpal bone) of his right hand gets fractured that is the d. Xylene
type of which bone? e. Paraffin wax
a. Long bone
b. Short bone 14. Osteomalacia is the improper mineralization of bone due to a
c. Irregular bone lack of available calcium and phosphate in which bones
d. Pneumatic bone density decreases and the bones become soft . which of the
e. Flat bone following cells are responsible for bone mineralization?
 a. Osteocytes which reveals extra uterine ( ectopic) pregnancy. What is the
b. Osteoclast most common site of ectopic pregnancy?
c. Osteoblast a. Cervix of the uterus
d. Stem cells b. Mesentery
e. Fibroblast c. Ovary
d. Uterine tube
15. Histologist was discussing the function of different organelles e. Peritoneum
in our body including peroxisomes which are found abundant
in following organs? 23. Mrs. Ali in her sixth month of pregnancy is worried about her
a. Liver cells fetal well-being as she does not feel fetal movements?
b. Reproductive cells Normally fetal movements (quickening) is felt by mother in
c. Cardiac cells which month of intrauterine life?
d. Brain cells a. Third month
e. Keratinocytes b. Fourth month
c. Fifth month
16. A middle aged patient presents with history of pain or d. Sixth month
burning while urinating, frequent urination, feeling the need e. Seventh month
to urinate despite having an empty bladder. Which of the
following type of epithelium lines the urinary bladder? 24. In hypertensive woman ultrasound shows abnormal
a. Cuboidal epithelium formation of placental membrane, which one of following
b. Ciliated columnar epithelium cellular layer form placental membrane after fourth month of
c. Stratified epithelium intrauterine life.
d. Transitional epithelium a. Spiral artery wall and cytotrophoblast
e. Simple squamous epithelium b. Syncytiotrophoblast , cytotrophoblast, villi connective tissue
and fetal capillary endothelium
17. Vitligo is an autoimmune disease of skin in which the areas of c. Maternal lacuna, trophoblast layer, endothelial and fetal red
symmetrical depigmentation appear, which are more blood cell
apparent in darker-skinned individuals, which of the cells are d. Fetal capillary endothelium, villi connective tissue,
responsible for skin colour? cytotrophoblast and synctiotrophoblast
a. Langerhans cell e. Syncytiotrophoblast and fetal capillary endothelium
b. Markel cell
c. Melanocytes 25. After fertilization of ovum, the corpus luteum produces
d. Keratinocytes progesterone which maintains the pregnancy. If the corpus
e. Epithelial cells luteum degenerates then abortion occurs. Which of the
following hormones maintains corpus luteum?
18. Bone fractures are common and usually occur due to trauma. a. Alpha-fetoprotein
Healing and repair of fracture is a specialized process which b. Estradiol
involves the formation of woven bone and over time mature c. Human chorionic gonadotropin
into compact bone that is made up of? d. Human placental lactogen
a. Haversian system e. Luteinizing hormone
b. Periosteum
c. Endosteum 26. Histopathology of a mass excised from back of neck region is
d. Cancellous bone diagnosed as melanoma, what is the embryological source of
e. Interstitial system melanocytes.
a. Surface ectoderm
19. Boy fell on the ground while riding the bicycle and his b. Endoderm
scaphoid bone (Carpal bone) of his right hand gets fractured c. Mesoderm
that is the type of which bone? d. Neural crest cell
a. Long bone e. Neurocectoderm
b. Short bone
c. Irregular bone 27. A 30 year old pregnant female visited her doctor for
d. Pneumatic bone complaint of high blood pressure in her pregnancy and avoid
e. Flat bone taking medicine. Doctor council her, high blood pressure
might results in uteroplacental insufficiency and fetal growth
20. During microscopy histologist finds goblet cells in a tissue retardation. Which of the following chorionic villi facilitate
what type of epithelium is associated with goblet cells? exchange may be affected?
a. Simple squamous epithelium a. Branch
b. Simple cuboidal epithelium b. Stem
c. Simple columnar epithelium c. Tertiary
d. Stratified squamous epithelium d. Anchoring
e. Pseudostratified epithelium e. Free

21. First year students during practical test look for which of the 28. A 30 years lady doctor posted in radiology department since
following cell organelle not bound by membrane? 05 years presents with history of 03 recurrent abortions with
a. Lysosomes gross malformation to her consultant. After examination and
b. Peroxisomes investigation no any significant cause found. Doctor advise
c. Centrioles her to have preventive measures at work place in early
d. Mitochondria pregnancy, which of the following period is potentially
e. Endoplasmic reticulum sensitive regarding development and defects?
a. 1st-2nd week
22. Mrs. Aftab after missing her menustrual cycle for b. 3rd -4th week
confirmation of pregnancy visits a sonologist for ultrasound, c. 4th-5th week
d. 4th -6th week
 e. 3rd -8th week d. Neurons form synapses
e. Neurons have immunity
29. During in vitro fertilization, an ovum is collected from 37. A patient complaining of insomnia (loss of sleep) comes to you
peritoneal cavity by ultrasound guidance soon after ovulation for the sake of treatment. In order to induce sleep you have to
which is arrested at which phase of cell division? make his brain cell less active. For that purpose you give him
a. Prophase of meiosis –I a hypnotic (sleep inducing) drug. This drug induces sleep by:
b. Metaphase of meiosis –I a. Bringing membrane potential closer to the firing level
c. Prophase of meiosis-II b. Inducing Na+ influx
d. Metaphase of meiosis –II c. Inducing K+ influx
e. Interphase d. Hyperpolarizing the cell
e. Inactivating Na+-K + pump
30. PHYSIOLOGY
38. When action potential reaches pre-synaptic membrane its
Glucose uptake into skeletal muscle occurs through GLUT 4 permeability increases for which ions:
under the influence of insulin by following transport a. Calcium ions
mechanism. b. Sodium ions
a. Simple diffusion c. Potassium ions
b. Facilitated diffusion d. Magnesium ions
c. Primary active transport e. Chloride ions
d. Co-transport
e. Counter-transport 39. Acetylcholine receptors are present on:
a. Postsynaptic membrane
31. A young man has applied body spray, soon he feels that the b. Presynaptic knob
fragrance has spread to his entire room, which mechanism of c. Synaptic cleft
transport comes into your mind for this phenomenon. d. Reticular fibers
a. Primary active transport e. Nucleus
b. Secondary active transport 40. When injured cell dies from dead cell volume enzyme are
c. Facilitated diffusion release that cause auto digestion of cell from which organelle
d. Simple diffusion these enzymes are released.
e. Osmosis a. Ribosome
b. Lysosome
32. Which one of the following system plays important role in c. Peroxisomes
homeostasis d. Golgi complex
a. Respiratory & excretory system e. Mitochondria
b. GIT & urinary system
c. Nervous & endocrine system 41. A 40 year old woman presented at outpatient department
d. Lymphatic & respiratory system with muscle weakness that became worse during evening. To
e. Endocrine & circulatory system make the diagnosis she was given a drug that caused
immediate improvement in her condition. She was diagnosed
33. The intracellular organelle act as “Cellular Trucks” and as having myasthenia gravis. What is possible action of
transport cargo like mRNA from the nucleus to the during given to her
cytoplasm: a. It increases the number of cholinergic receptors at motor end
a. Vaults plate
b. Microtubules b. Binds to and activate more cholinergic receptors at motor end
c. Lysosomes plate
d. Peroxisomes c. Releases more acetylcholine from axon terminals
e. Microfilaments d. It inactivates the acetylcholinestrase
e. It promotes the synthesis of acetylcholine
34. A new born child is suffering from a congenital disease.
Doctors say that it is caused by a gene mutation. Mutation is 42. Due to following single- unit muscle cells can stimulate each
basically an alteration in the structure of: other because they have
a. Protein a. Latch bridges
b. RNA b. Diffuse junctions
c. Genetic code c. Gap junctions
d. Operon d. Tight junctions
e. Enzyme e. Calcium pumps
35. Acetylcholine must be removed from the neuromuscular cleft
if the muscle fibre is to be able to react; this is achieved by 43. Potential weight lifter started his session by lifting 25kg and
a. Diffusion then he went on and lifted 50,75 and 100kg. what is the most
b. Reabsorption likely mechanism that enabled him increase his force four
c. Enzymatic breakdown time
d. Osmosis a. Changing initial length of his muscle
e. Re-uptake b. Recruitment of motor units
c. Increasing frequency of stimulation of muscles
36. A 70 year-old doctor develops astrocytoma, a brain tumor.he d. Increasing the release of calcium with increased load
ask the physician what is astrocytoma.Doctor tells him that e. Increasing the size of motor units
it is tumor of neuroglia astrocytes. He then asks is it a tumor
of neurons; Doctor tells him neurons cannot form tumors 44. The genesis of resting membrane potential primarily depends
after birth. Why neurons cannot form tumors after birth. on
Because a. Passive leakage of K+ outside the cell
a. Neurons cannot divide b. Active transport of Na+ inside the cell
b. Neurons have low RMP c. Operation of the Na+/K+ pump
c. Neurons are always exited d. Trapping of protein ions inside the cell
 e. Inward movement of the Cl ions 54. The polysaccharide used in assessing the glomerular filtration
rate (GFR) is:
45. Mature messenger RNA is formed from a. Inulin
a. Small nuclear RNA b. Agar
b. Micro RNA c. Glycogen
c. Transfer RNA d. Hyaluronic acid
d. Precursor messenger RNA e. Dextrin
e. Ribosomal RNA
55. Repeating units of hyaluronic acid are:
46. BIOCHEMISTRY a. L-iduronic acid and glucosamine
b. N-acetyl galactosamine and D-glucuronic acid
Which of the following is essential for primary structure of c. N-acetyl galactosamine and D –glucuronic acid
proteins? d. N-acetyl glucosamine and galactose
a. Hydrogen bonds e. N-acetyl galactosamine and L- iduronic acid
b. Ionic bonds
c. Vander wall forces 56. The site to which RNA polymerase binds on the DNA
d. Disulfide bonds template prior to the initiation of transcription:
e. Peptide bonds a. Intron/exon junction
b. Terminator
47. Cell Membrane: c. Coding region
a. More permeable to K+ than Na+ d. Initiator methionine codon
b. A semi permeable membrane e. Promoter
c. Composed chiefly of lipids
d. The main site of ATP synthesis 57. Which of the following does NOT contain phosphate?
e. Composed of two layers of lipids and proteins a. Nucleoside
b. Nucleotide
48. D-sugars that differ in configuration at only a single c. DNA
asymmetric carbon atom are: d. RNA
a. Stereoisomer e. ATP
b. Anomers
c. Optical isomers 58. Cholesterol is transported from liver to peripheral tissue via
d. Epimers blood mainly in the form:
e. Polymers a. Chylomicrons
b. Albumin complex
49. Cholesterol: c. VLDL
a. Is converted to cholic acid in our body d. LDL
b. Is precursor of Vitamin –C e. HDL
c. Level in serum is 50-80mg/dl
d. Synthesis decreases by low intake of cholesterol in diet 59. The major extracellular structural protein in connective
e. Mainly present in free form tissue and bone is:
a. Actin
50. The three major lipid components of animal cell membrane b. Alpha keratin
are: c. Elastin
a. Glycolipids, prostaglandins & cholesterol esters d. Collagen
b. Triacylglycerols, free fatty acids and cholesterol e. Myosin
c. Phospholipids, sphingolipids & cholesterol esters
d. Triacylglycerols, phospholipids & cholesterol esters 60. Glucose upon reduction produces
e. Phospholipids, dolichol & free fatty acids a. Glucuronic
b. Glucaric acid
51. Which of the following is not a conjugate protein? c. Sorbitol
a. Albumin d. Mannitol
b. LDL e. Gluconic acid
c. Glycoprotein
d. Visual Purple 61. Which portion of mitochondria plays important role in
e. Proteoglycan electron transport chain?
a. Outer membrane
52. Which of the following is responsible for specifying the 3D b. Matrix
shape of a protein? c. Cristae
a. The peptide bond d. Inner membrane
b. The amino acid sequence e. All of above
c. Interaction with other polypeptides
d. Interaction with molecular chaperons 62. PATHOLOGY
e. Quaternary structure of protein
A 48-year old woman has a malignant lymphoma, treated with
53. Which of the following is a non-polar amino acid? a chemotherapeutic agent which results in the loss of individual
a. Alanine neoplastic cells through fragmentation of individual cell nuclei
b. Glycine and cytoplasm by which one of the following mechanism?
c. Serine a. Coagulative necrosis
d. Threonine b. Mitochondrial poisoning
e. Tyrosine c. Phagocytosis
d. Acute inflammation
e. Apoptosis
63. A 20 year old man presents with yellowish of sclera. Skin and d. Teichoic acid
oral mucosa.Which of the following accumulations underlying e. Diaminopimelic acid
these findings.
a. Bilirubin 72. PHARMACOLOGY
b. Hemosiderin
c. Lead
Which of the following is enteral route of drug administration?
d. Melanin
a. Skin
e. Silver
b. Rectal
c. Pulmonary
64. On ultrasound examination of 71 years old male reveals
d. Intravenous
diffusely enlarged prostate. Which of the following represents
e. Intramuscular
a pathologic change leading to this man’s problem?
a. Dysplasia
73. Main intracellular site of drug metabolism is :
b. Hypertrophy
a. Cell membrane
c. Hyperplasia
b. Cytoplasm
d. Metaplasia
c. Nucleus
e. Neoplasia
d. Rough endoplasmic reticulum
e. Smooth endoplasmic reticulum
65. A 40 year-old woman has the sudden onset of severe
abdominal pain. An abdominal CT Sean reveals an
74. The effects of the body on the drug is called:
enlargement of the pancreas with chalky white areas. Which
a. Elimination
of the following cellular changes is most likely seen.
b. Pharmacokinetics
a. Coagulative necrosis
c. Absorption
b. Dry gangrene
d. Distribution
c. Fat necrosis
e. First order kinetics
d. Apoptosis
e. Liquefactive necrosis
75. Which type of passage of drug crosses membrane requires
energy?
66. Features of reversible cell injury
a. Simple diffusion
a. Lysosomal rupture
b. Filtration
b. Bellbs formation on membrane
c. Active transport
c. Pyknosis
d. Facilitated diffusion
d. Severe mitochondrial dysfunction
e. Pinocytosis
e. Karryolysis
76. Agonist is the drug which has got?
67. Which of the following chromosomal aberration causes Down
a. Affinity
syndrome
b. Affinity as well as intrinsic activity
a. Trisomy 13
c. Intrinsic activity
b. Trisomy 18
d. Affinity but less intrinsic activity
c. Trisomy 21
e. Affinity but no intrinsic activity
d. Trisomy 15
e. Trisomy 10
77. On repeated administration of drug if response decreases
abruptly this is known as:
68. Translocation of chromosome between two homologous
a. Physical Dependence
chromosome is called
b. Potentiation
a. Reciprocal translocation
c. Tachyphylaxis
b. Non reciprocal translocation
d. Physiological dependence
c. Non homologous translocation
e. Antagonism
d. Homologous translocation
e. Robertsonian translocation
78. COMMUNITY MEDICINE
69. The polymerase chain reaction is
a. It is a DNA sequencing technique Awareness regarding breast cancer to female medical students
b. It is a DNA amplification technique is which type of intervention:
c. It is a DNA degradation technique a. Early detection of disease
d. It is a RNA amplification technique b. Limiting the disability
e. It is a RNA sequencing technique c. Health promotion
d. Specific protection
70. A 14 years old boy came to endocrinologist, identified on the e. Rehabilitation
basis of history combination of gynecomastia and small testes.
He advised karyotyping. A chromosomal study reveals a 47, 79. Primary health care services are the basic health services
XXY karyotype. provided at the door step of people. Which of the following is
a. Downs syndrome the selective primary health care services?
b. Edward syndrome a. Availability of drugs
c. Robert Somnion syndrome b. Providing health education
d. Klinefelter syndrome c. Water and sanitation
e. Turner syndrome d. Immunization
e. Availability of health care providers
71. Which of the following components is present in gram-
positive bacteria but not in gram-negative bacteria/ 80. Which of the following is the intervention for the secondary
a. Peptidoglycan prevention?
b. Capsule a. Mass-vaccination against COVID
c. Flagella b. Provision of tuberculosis drug regimen for TB patient
 c. Youth peer education on family planning and contraception Hematocrit: 60% hemoglobin: 22g/dl, RBC count: 10 million
d. Speech therapy following stroke attack per mm3. This subject is probably suffering from.
e. Provision of helmets for construction workers a. Megaloblastic anemia
b. Polycythemia Vera
81. The science of protecting populations and improving the c. Aplastic anemia
health of human communities through education is called d. Secondary polycythemia
a. Preventive medicine e. Leukemia
b. Epidemiology
c. Public health 89. Which of the following is the most common form of
d. Sociology hemoglobin in a normal adult human
e. Community medicine a. HbA1c
b. HbA2
82. The number of deaths in people over 65 years expressed as c. HbS
percentage of total deaths of all age groups is known as; d. HbA
a. Crude death rate e. HbF
b. Expectancy of life at 65 years
c. Adjusted Death Rate 90. If a patient has anemia, gastric atrophy, raised IgG in the
d. Proportional mortality rate serum and macrocytic red blood cells, then he is suffering
e. Specific death rate from:
a. Iron deficiency anemia
83. BLOOD MODULE b. Sickle cell anemia
c. Hemolytic Anemia
d. Pernicious Anemia
ANATOMY e. Thalassemia

After maturation in thymus T lymphocyte migrate 91. A patient’s intestine was resected from intestinal perforation,
preferentially to which following sites? later he developed megaloblastic anemia which part of the
a. Paracortex of lymph nodes intestine was probably removed in this patient
b. Cortical lymphoid nodules of lymph nodes a. Duodenum
c. Hilus of lymph nodes b. Ileum
d. Lymphoid nodules of tonsil c. Jejunum
e. Lymphoid nodules of the spleen d. Sigmoid colon
e. Transverse colon
84. A 4 year child brought to ENT specialist with complain of
recurrent high grade fever cough and inflamed tonsils, which 92. A girl got a mosquito bite in her arm resulting in severe
of the following is the histological features of tonsil? itching and red swollen skin, these effects are due to
a. Trabeculae activation of:
b. Septa a. Esinophils
c. Venus sinus b. Mast cells
d. Tonsillar crypts c. Neutrophils
e. Tonsillar Cords d. T lymphocytes
e. Monocytes
85. A diagnosed case of von Willebrand disease shows defect in
platelet activation which are of the following shape? 93. Antibodies can destroy foreign antigens by which of the
a. Stellate shape following mechanism;
b. Round shape a. Activation of T-Cells
c. Convulated shape b. Formation of interferons
d. Kidney shape c. Formation of pores in antigens
e. Oval shape d. Activation of complement
e. Formation of memory cells
86. During embryogenesis which of the following is the earliest
site of hematopoiesis: 94. Release of chemicals from basophils & mast cells are
a. Bone marrow responsible for which type of reaction in the body.
b. Liver a. Anti-allergic reaction
c. Spleen b. Acute inflammatory reaction
d. Yolk sac c. Anaphylactic reaction
e. Thymus d. Auto immune reaction
e. Chronic inflammatory reaction
87. PHYSIOLOGY
95. The primary response of anti-body formation means the
The lack/ deficiency of which of the following nutrient is most formation of anti-bodies:
likely to cause failure of nuclear maturation and cell division in a. On first exposure of an antigen
the process of erythropoiesis b. On second exposure of same antigen
a. Vitamin B12 c. Against self-antigens
b. Vitamin B1 d. Before birth
c. Vitamin C e. After birth
d. Copper
e. Iron 96. Which of the following immunoglobulin is found in the
secretions of digestive, respiratory and genitourinary systems
88. Blood sample taken from a young man living in hyderabad a. IgG
showed the following values: b. IgA
c. IgD
d. IgE
 e. IgM c. Eosinophils
d. Basophiles
97. A 02 years old boy is bought to hospital for circumcision, e. Monocytes
there is a history of prolong bleeding from the cord in the
past, his two cousins have bleeding diathesis. The disease is 105. Major histocompatibility complex (MHC)-II present on:
confirmed by: a. B-lymphocytes
a. Activated partial thromboplastin time (APTT) b. CD8-Cells
b. Bleeding time c. CD4 Cells
c. Clotting time d. Suppressor T-Cells
d. Prothrombin time (PT) e. T lymphocytes
e. Platelate Count
106. BIOCHEMISTRY
98. A women took her one year old son to hospital for
circumcision, after the operation she observed that her child Extra corpuscular hemoglobin binds to which of the following
continued bleeding from his wound for 2 hour; she recalled plasma proteins?
that there is a history of bleeding disorders in the male a. Albumin
members of her family. This infant is most likely to have: b. Heptoglobin
a. Factor VIII deficiency c. Transferrin
b. Thrombocytopenia d. Cerculoplasmin
c. Afibrinogenemia e. Transcortin
d. Von Wille-brand disease
e. Capillary abnormality 107. The factor causing Hb to release 02 readily is:
a. Alkalosis
99. A women has severe post partum hemorrhage and is gone b. Raised production of 2,3-BPG
into circulatory shock. Her blood group is B negative, which c. Hyperventilation leading to low level of CO2
of the following available stored blood would you selects to d. Replacement of the Beta-subunit with gamma-subunits
infuse her e. None of the above
a. O positive
b. AB negative 108. The first bile pigment formed during heme catabolism is:
c. AB positive a. Cholic acid
d. O negative b. Bilirubin
e. B positive c. Lithocholic acid
d. Biliverdin
100. In the laboratory while testing for the blood group of one of e. Deoxycholic acid
your colleagues, you observe agglutination with antisera A
and antisera D. your colleague’s blood will have which one of 109. Increased prothrombin time is observed in a deficiency of
the following Agglutinogens a. Vitamin B12
a. A b. Folic acid
b. B c. Vitamin C
c. D d. Vitamin D
d. A & D e. Vitamin K
e. AB
110. Hemoglobin F Consists of :
101. Most important targets of attack for cytotoxic- T Cells are a. 2 alpha and 2 gamma Chains
a. Virus/ bacterial infected cells b. 2 Alpha and 2 beta Chains
b. Tumor Cells/ foreign cells c. 2 alpha and 2 delta chains
c. Transplanted / own cells d. 2 alpha and 2 epsilon chains
d. Bacterial/ Fungal infected cells e. 2 alpha and 2 zeta chains
e. Dead macrophages
111. Heme is a tetrapyrrole structure consisting of Fe+2 ions in the
102. During routine blood typing, the red blood of a person are center of the porphyrin ring. Which of the following proteins
mixed with anti sera A, anti sera B and anti sera D separately. does not consist of heme?
The agglutination is observed only with anti sera A. What is a. Myoglobin
the blood group of that person? b. Hemoglobin
a. AB-Positive c. Cytochrome
b. AB-negative d. Ferritin
c. A-negative e. C and D
d. O-negative
e. Rh-positive 112. Which of the following is the rate-limiting enzyme for the
synthesis of heme?
103. A 25 year- old lady has RBC count 3.7millions/c.mm and a. Delta aminolevulinic acid synthase I
hemoglobin concentration 8 gm/100 ml of blood. Which of the b. Uroporphyrinogen synthase III
following is least likely to expect in this lady? c. Protoporphyrinogen oxidase
a. Decreased oxygen-carrying capacity of the blood d. Ferrochelatase
b. Decreased colloid osmotic pressure of the blood e. None of the above
c. Increased work-load of the heart
d. Decreased blood viscosity 113. The porphyrias are a group of metabolic disorderes that
e. Change in hemoglobin chain configuration result from partial deficiencies of the enzyme of the heme
biosynthetic pathway. The porphyrias may be classified as
104. A 16 years old boy was brought to operation theater for acute and nonacute. Which of the following porphyria is not
appendectomy, which of the following cells would be raised: acute type?
a. Neutrophils a. Acute intermittent porphyria
b. Lymphocytes
 b. Hereditary corpoporphyria a. Anemia of chronic disease
c. Variegate porphyria b. Beta thalassemia
d. Porphyria cutanea torda c. Iron deficiency anemia
e. B and D d. Lead poisoning
e. Sideroblastic anemia
114. Adult hemoglobin (HbA) is a tetramer consisting of
a. a2b2 123. Patient with X-linked agammaglobunemia (Bruton’s disease)
b. a2d2 are known to:
c. a2g2 a. Exhibit profound deficiencies of cell-mediated immunity
d. b4 b. Have very low quantities of immunoglobulin in their serum
e. g4 c. Have normal numbers of B-lymphocytes
d. Have a depletion of lymphocyte in the para-cortical areas of
115. Folate trap occurs when the methyl-tetrahydrofolate is lymph nodes.
accumulated and not recycled into tetrahydrofolate. Which of e. Be particularly susceptible to viral & fungal infections
the vitamin deficiency lead to folate trap?
a. Pyridoxine 124. Which of the following is an example of type III
b. Niacin hypersensitivity reaction?
c. Cobalamin a. Good pasture syndrome
d. Riboflavin b. Allergies
e. None of the above c. Farmer’s lung
d. Autoimmune hemolytic anemia
116. Abnormal variety of hemoglobin is: e. Anaphylaxis
a. Hb-A
b. Hb-F 125. Which of the following hypersensitivity reaction occur as a
c. Hb-A2 result of massive deposition of immune complex in a various
d. Hb-C tissues? These immune complex produce complement
e. Gower-II Hb activation and inflammation response:
a. Type I hypersensitivity
117. Final step of heme synthesis occurs in b. Type III hypersensitivity
a. Rough endoplasmic reticulum c. Type II hypersensitivity
b. Golgi apparatus d. Type IV hypersensitivity
c. Secretory vesicle e. Arthus reaction
d. Mitochondrtia
e. Cytosol 126. In which of the following lymphoma presence of Reed-
Sternberg cells are characteristic finding?
118. PATHOLOGY a. Burkitt lymphoma
b. Follicular lymphoma
Which of the following is most likely a major risk factor for c. Mental cell lymphoma
venous thrombosis? d. Hodgkin lymphoma
a. Smoking e. Diffuse large B-cell lymphoma
b. High cholesterol
c. Hypertension 127. A 4-year old boy presented with prolonged bleeding after
d. Cancer circumsicion. The lab test shows normal platelets
e. Pregnancy count,normal bleeding time, normal Prothrombin and
isolated APTT prolonged. The most likely diagnosis is:
119. What is the least amount required for the symptoms in Air a. Haemophilia
embolism? b. Bernard soulier syndrome
a. 100 ml c. Factor VII deficiency
b. 50 ml d. Factor XIII deficiency
c. 40 ml e. Glanzman thrombasthenia
d. 20 ml
e. 10 ml 128. The leucocytes recognize and digest foreign
material/microorganism through process of:
120. Which one of the following is not true about G6PD a. Margination
deficiency? b. Adhesion
a. Leads to intravascular hemolysis after certain infections c. Phagocytosis
b. Commonly presents as chronic hemolytic anemia d. Chemotaxis
c. Protects against malaria e. Rolling
d. It is X-linked recessive disorder
e. It is also a cause of neonatal jaundice 129. Most common exogenous chemoattractant is:
a. Bacterial products
121. Which one of the following is most likely a cause of b. Chemokines
intravascular hemolysis? c. C3a
a. Hereditary spherocytosis d. C5a
b. Hemolytic disease of new born e. Leukotriene B4
c. Thalassaemia
d. Glucose-6-Phosphate dehydrogenase deficiency 130. Exudate is an extracellular fluid that has:
e. Sickle cell anemia a. Low protein concentration and little or no cellular material
b. High protein concentration and cellular debris
122. A 31 year old women was found to have Hb 6.8 mg/dl, MCV c. Normal vascular permeability
50fl. Peripheral film showed microcytic hypochromic RBCs d. Specific gravity less than 1.018
with pencil cell. Serum iron low and Total iron binding e. Decreased intraendothelial spaces
capacity increase. The most likely diagnosis is:
131. In the multistep process of leukocytes migration through c. X-ray exposure
blood vessel rolling is mediated by set of proteins called: d. Radiation
a. Selectins e. Smoking
b. Integrins
c. Defensin 140. Severity of disease, (Mild, Moderate, severe) or level of
d. Endothelin knowledge is an example of:
e. Interleukin a. Ordinal variable
b. Nominal variable
132. Hallmark of acute inflammation is: c. Continuous variable
a. Stasis d. Discrete variable
b. Vasoconstriction e. Quantitative variable
c. Leukocyte margination
d. Increase vascular permeability 141. How is random sampling helpful?
e. Vasodilation a. Reasonably accurate
b. An economical method of data collection
133. PHARMACOLOGY c. Free from personal biases
d. All of the above
Which of the following is drug used for bleeding disorder? e. A and C
a. Vitamin K
b. Streptokinase 142. ____________ is the classical form of research?
c. Warfarin a. Experiment
d. Heparin b. Case study
e. Aspirin c. Grounded theory
d. Narrative theory
134. Which of the following drug that helps to prevent the clotting e. All of the above
of the blood by acting on the coagulation phase?
a. Vitamin K 143. Statistics is used by the researchers to:
b. Fibrinogen a. Analyze the empirical data collected in study
c. Adrenaline b. Make their findings sound better
d. Heparin c. Operationally define their variables
e. Antihemophilic factor d. Ensure the study comes out the way it was intended
e. All of the above
135. Which one the following is antidote of heparin?
a. Warfarin 144. BIOMEDICAL ETHICS
b. Protamine sulphate
c. Vitamin K The field of bioethics underwent explosive expansion in?
d. Alum a. 17th century
e. Streptokinase b. 18th century
c. 19th century
136. Which of the following drug is recommended for the d. 20th century
treatment of megaloblastic anemia? e. 21st century
a. Folic acid
b. Vitamin B12 145. A relationship characterized by the active involvement of
c. Erythropoietin patients as more equal partners in the consultation is called?
d. None of these a. Paternalism
e. Vit A b. Consumerist
c. Default
137. COMMUNITY MEDICINE d. Mutualistic
e. Weak paternalism
Hepatitis B immune globulin was given to a 13 year old boy
146. Material presented by pharmaceutical sales representatives,
which will provide him with passive immunity. One of the
90% of material is accurate and biased towards the
following advantage of passive immunity is that;
manufacturer’s product. 10% of material is?
a. Has effects that last a long time
a. True
b. Is highly effective in the treatment of disease
b. False
c. Offers immediate protection
c. True positive
d. Encourages the body to produce antibodies
d. False positive
e. Can be effective both before or after the infection
e. Fake
138. A new infant is brought at EPI centre, in accordance to the
recent EPI schedule, which of the following vaccines are 147. IT
recommended at birth/
a. BCG, OPV and Hepatitis B ___________ is the type of an operating system?
b. OPV and DPT a. Hardware
c. OPV and Penta valent b. Linux
d. OPV, BCG and Rotavirus vaccine c. Data
e. OPV, Hepatitis B and Penta valent d. Application software

139. RESEARCH 148. A printer is a device that accepts text and graphic output
from a computer and transfers the information to:
a. HDD
Which of the following is an example of dependent variable?
b. USB
a. Noise pollution
c. Paper
b. Lungs cancer
 d. Monitor

149. A readable printed copy of computer output is:

a. Softcopy
b. Hardcopy
c. Hard and soft copy
d. None of the above

150. A readable printed copy of computer output is:

a. Softcopy
b. Hardcopy
c. Hard and soft copy
d. None of the above