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Elsevier. Big Data and Total Hip Arthroplasty How Do Large Databases Compare
Elsevier. Big Data and Total Hip Arthroplasty How Do Large Databases Compare
Big Data and Total Hip Arthroplasty: How Do Large Databases Compare?
Nicholas A. Bedard, M.D., Andrew J. Pugely, M.D., Michael A. McHugh, B.S., Nathan
R. Lux, Kevin J. Bozic, M.D., MBA, John J. Callaghan, M.D.
PII: S0883-5403(17)30786-6
DOI: 10.1016/j.arth.2017.09.003
Reference: YARTH 56077
Please cite this article as: Bedard NA, Pugely AJ, McHugh MA, Lux NR, Bozic KJ, Callaghan JJ, Big
Data and Total Hip Arthroplasty: How Do Large Databases Compare?, The Journal of Arthroplasty
(2017), doi: 10.1016/j.arth.2017.09.003.
This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to
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Big Data and Total Hip Arthroplasty: How Do Large Databases Compare?
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Kevin J. Bozic M.D., MBA2
John J. Callaghan, M.D.1
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Author Affiliation:
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1. The Department of Orthopaedic Surgery and Rehabilitation, University of Iowa Hospitals
and Clinics; Iowa City, Iowa
2. The Department of Surgery & Perioperative Care, Dell Medical School at the University
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of Texas at Austin; Austin, Texas
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Corresponding Author:
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Nicholas Bedard, MD
University of Iowa Hospitals and Clinics
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Department of Orthopaedics
200 Hawkins Drive, 01029 JPP
Iowa City, IA 52242
nicholas-bedard@uiowa.edu
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1 Big Data and Total Hip Arthroplasty: How Do Large Databases Compare?
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3 Abstract
4 Background: Use of large databases for orthopaedic research has become extremely popular in
5 recent years. Each database varies in the methods used to capture data and the population it
6 represents. The purpose of this study was to evaluate how these databases differed in reported
7 demographics, comorbidities and post-operative complications for primary total hip arthroplasty
8 patients.
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10 Methods: Primary THA patients were identified within National Surgical Quality Improvement
11 Programs (NSQIP), Nationwide Inpatient Sample (NIS), Medicare Standard Analytic Files
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12 (MED) and Humana administrative claims database (HAC). NSQIP definitions for comorbidities
13 and complications were matched to corresponding ICD-9/CPT codes to query the other
14 databases. Demographics, comorbidities, postoperative complications were compared.
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16 Results: The number of patients from each database was 22,644 in HAC, 371,715 in MED,
17 188,779 in NIS and 27,818 in NSQIP. Age and gender distribution were clinically similar.
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18 Overall there was variation in prevalence of comorbidities and rates of postoperative
19 complications between databases. As an example, NSQIP had more than twice the obesity than
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20 NIS. HAC and MED had more than two times the diabetics than NSQIP. Rates of deep infection
21 and stroke 30-days after THA had more than twofold difference between all databases
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26 Additionally, with the advent of bundled payments, these differences must be considered in risk
27 adjustment models.
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29 Keywords: Total hip arthroplasty, big data, database, clinical registry
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31 Introduction:
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33 Over the last ten years, the use of big databases has increased substantially within the
34 field of orthopaedics (Figure 1) [1-3]. Clinical registries and administrative claims databases
35 have given researchers access to large cohorts of patients that allow for a more unique analysis of
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36 surgical complications, risk factors for such complications, trends in procedures and issues
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37 related to cost of care. Additionally, these large datasets are now being used for the public
38 reporting of surgical outcomes, with subsequent penalties for underperforming institutions [4, 5].
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39 Although similar in their ability to analyze large cohorts of patients and answer questions
40 difficulty to address with single institution type studies, each of these databases represent a
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unique patient population, and vary in their methods of acquiring data [1-3]. Recent literature
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42 across multiple surgical specialties has begun to suggest that intrinsic differences in the methods
of data collection and the population of patients analyzed result in variability of reported
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44 comorbidities and surgical complications [6-12]. Understanding the differences between these
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45 databases is important for appropriately evaluating research utilizing them. Despite a significant
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46 amount of total hip arthroplasty (THA) literature being published utilizing these databases
47 (Figure 1), little has been done to evaluate the impact of a given databases on reported rates of
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48 comorbidities and complications following THA. Therefore, the purpose of this study was to
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52 Methods:
53 Four large multicenter databases were utilized to complete this study: National Surgical
54 Quality Improvement Program (NSQIP), Nationwide Inpatient Sample (NIS), Medicare Standard
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55 Analytic Files (MED) and Humana administrative claims database (HAC). Patients who had a
56 primary THA were identified using the International Classification of Diseases, 9th Revision
57 (ICD-9) code 81.51 and/or the Current Procedural Terminology (CPT) code 27130. Only
58 procedures performed between the years 2010 to 2012 were analyzed as these were the years
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59 common to all datasets. All four databases are Health Insurance Portability and Accountability
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60 Act (HIPAA) compliant and were found to be exempt from institutional review board approval
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62 Three of the four databases utilized (HAC, MED, NIS) are administrative claims
63 databases and thus the data included in them are defined by reimbursement data linked to ICD-9
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and/or CPT codes. The HAC database represents approximately 20 million lives and includes
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65 both privately insured patients and those who have purchased their Medicare/Medicaid
Advantage plans through Humana Inc. The MED database represented approximately 51 million
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67 covered lives and is derived from Medicare parts A and B. Both of these databases capture
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68 inpatient and outpatient events and utilized both CPT and ICD-9 codes. The NIS consists of a
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69 20% sample of all inpatient discharges and includes only inpatient data. Similar to HAC and
70 MED, NIS comorbidity and adverse event data are defined by reimbursement data for the
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71 inpatient admission of interest; however, only ICD-9 codes are supported by NIS. The NSQIP
73 comorbidities, procedure details and post-operative complications for patients undergoing major
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74 surgical procedures [13]. This database captures both inpatient and outpatient events occurring
75 within thirty-days following the surgical procedure of interest and uses trained clinical reviewers
76 to perform data collection through chart review and patient/surgeon contact utilizing strict
77 definitions for each comorbidity and complication variable cataloged (Table 1) [13].
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78 Definitions from the NSQIP user manual for seven comorbidities (morbid obesity,
80 and smoking) and nine postoperative complications (deep vein thrombosis (DVT), pneumonia,
81 stroke, myocardial infarction, cardiac arrest, pulmonary embolism (PE), wound dehiscence, deep
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82 surgical site infection (SSI), and any SSI) were matched to corresponding ICD-9 and CPT codes
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83 (Appendix 1 and 2). The PearlDiver Research Program (www.pearldiverin.com; PearlDiver Inc,
84 Fort Wayne, IN) was then used to query the three administrative claims databases (HAC, MED,
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85 NIS) using these ICD-9 and CPT codes. Demographic variables of age at the time of THA and
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The prevalence of complications following THA that occurred during the hospital stay
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88 were compared across all four databases. Given that wound dehisce following primary THA
occurred so infrequently during the inpatient stay we were not able compare the comorbidity
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90 variable as HIPAA compliant databases are unable to report exact numbers when the value of the
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91 endpoint of interest lies between zero and ten. Complications that occurred within thirty-days
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92 following the primary THA procedure were compared amongst databases with that interval of
93 follow-up available (HAC, MED, NSQIP). Lastly, the differences in rates of complications
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94 occurring during the inpatient stay versus those occurring within thirty-days following surgery
95 were compared for databases with both of these times points available (HAC, MED, NSQIP).
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96 Pearson chi-square test was utilized to compare demographic variables with a p value of
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97 <0.05 considered significant. Relative risk (RR) and corresponding 95% confidence intervals
98 were utilized to compare the prevalence of comorbidities and complications between databases.
99 However, consistent with other database comparison studies, the large sample sizes and
100 associated high power allowed for detection of statistical significance for small, clinically
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101 insignificant differences [6, 7]. Thus, the focus of these comparisons was on the magnitude of the
102 differences, specifically utilizing an absolute difference threshold of greater than twofold to
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105 Results:
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106 The number of primary THA patients analyzed in each database was: 22,644 in HAC,
107 371,715 in MED, 188,779 in NIS and 27,818 in NSQIP. The female to male ratio was 1.3:1 for
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108 NIS and NSQIP, 1.6:1 for MED and 1.4:1 for HAC (p <0.001). The age group distribution
109 between databases is seen in Figure 2 and comparisons at each age groups were statistically
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significant (p<0.001). The median age at time of THA fell within the 70-74 year old age group
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111 HAC, 75-79 year old group for MED and 65-69 year old age group for NIS and NSQIP (Figure
2).
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114 much variability between datasets (Figure 3, 4 and 5). Relative risk values and corresponding
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115 95% confidence intervals comparing these endpoints amongst each database can be found in in
116 Tables 2, 3 and 4. However, given that most comparison were statistically significant in the
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117 relative risk analysis despite many small clinically insignificant differences, the focus of these
118 comparisons is on the absolute difference in comorbidities and complication rates using a
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120 Comparison of comorbidities amongst patients in each database demonstrated HAC and
121 MED to have twice the prevalence of COPD, coagulopathy and diabetes than NSQIP. Similarly,
122 HAC and MED had over two times the prevalence of COPD and coagulopathy as NIS. Lastly,
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123 NSQIP had over twice the prevalence of obesity as NIS. All other comorbidity comparison were
125 Prevalence of complications occurring during the inpatient stay for primary THA
126 revealed HAC to have over twice the amount of complications than NSQIP for all variables
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127 analyzed. HAC had greater than two-fold prevalence of DVT and any SSI than MED and NIS.
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128 Additionally, HAC had over two times the amount of inpatient strokes as NIS. MED had more
129 than twice the amount of DVT, pneumonia, stroke, MI, cardiac arrest and any SSI as NSQIP.
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130 Lastly, NIS had over two-fold prevalence of pneumonia during the inpatient stay as NSQIP. All
131 other comparisons of inpatient complications were within two-fold difference between databases
HAC to have greater than two-fold prevalence of DVT, stroke and deep SSI compared to MED.
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135 Additionally, HAC had more than twice the prevalence of all complication endpoints analyzed
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136 relative to NSQIP. Comparing MED to NSQIP, revealed MED to have over two times the
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137 amount of pneumonia, stroke, MI, cardiac arrest, PE and wound dehiscence as NSQIP.
138 Conversely, NSQIP had more than twice the prevalence of deep SSI as MED. Prevalence of all
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139 other complications occurring within thirty-days of surgery were not different between databases
141 When comparing the number of complications captured by a given database relative to
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142 the duration of follow-up included (inpatient versus thirty-days following surgery), it was found
143 that over half of any SSI, deep SSI and DVTs are not captured by any database (NSQIP, HAC,
144 MED) if follow-up is limited to inpatient events only. Additionally, all complication variables at
145 least doubled in prevalence in the HAC database when follow-up was extended from inpatient
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146 only to thirty-days following THA. Lastly, over half of PEs were not captured by MED if only
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149 Discussion:
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150 As use of large databases continues to increase for orthopaedic research and assessments
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151 of hospital quality, this study demonstrates that amongst four commonly utilized databases there
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153 THA. These findings highlight the importance of understanding the methodology utilized build
154 each database and the population that is being captured for that dataset.
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We suspect that NSQIP, which utilized chart abstraction with strict definitions for each
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156 variable, is likely more accurate than administrative claims databases given limitations in ICD-
9/CPT codes and the reliance on accurate documentation. The suggestion that administrative
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158 claims data may be less accurate than clinical registries has recently begun to emerge within the
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159 literature across multiple surgical specialties [6-12]. Two studies within orthopaedics performed
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160 a similar analysis as our present study for patients who underwent lumbar spine surgery and for
161 hip fracture patients [6, 7]. They similarly found variability in prevalence of complications
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162 between NSQIP and NIS for each of the surgical procedures analyzed. Additionally, they also
163 cited the impact analysis of only the impatient stay (compared to thirty-day follow-up) has on the
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164 reported prevalence of complications after hip fracture and lumbar spine surgery [6, 7]. One
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165 strength the present study has over these analyses, is that multiple administrative claims
166 databases (MED, HAC, NIS) were compared amongst themselves and to NSQIP. This allowed
167 us to concluded that despite the data cited above, the differences in prevalence of complications
168 between databases cannot be entirely attributed to the type of database (administrative claims
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169 versus clinical registry) as even comparisons between multiple administrative claims databases
170 in this study had drastically different rates of surgical complications (Figure 4 and 5) despite
171 querying the database with the exact same methodology and coding algorithms.
172 Despite these results, we are not suggesting that databases that only include the inpatient
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173 stay or administrative claims databases have no role in the orthopaedic literate. Administrative
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174 claims databases such as HAC and MED are often more useful for evaluation of longer term
175 complications as they are not limited to a specific time period of analysis (ie 30 days
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176 postoperatively) and patients can be tracked the time period of the databases for specific events.
177 Evaluation of trends overtime and analysis of prevalence of a given intervention or complication
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seem to be best asses with databases such NIS, MED and HAC as they are more representative
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179 of the general population, patients are able to be tracked overtime and they generally have more
years of data included. Further administrative claims databases are better positioned for financial
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181 analysis as they are based upon reimbursement data. Additionally, although inpatient databases
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182 do not capture many short term complications that occur soon after discharge, they can be very
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183 important for evaluation of issues related to length of stay or inpatient events. Lastly, analysis of
184 questions outside the scope of strict clinical definitions often associated with clinical registries is
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185 better studied with administrative claims databases using diagnosis and procedure codes to
186 define outcomes not included in a given clinical registry. Clinical registries like NQSIP seem to
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187 be best suited for evaluation of specific comorbidities on given complications after surgical
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188 procedures given their strictly defined definitions for variables included and the prospective
189 collection of data by trained clinical reviewers. We believe these results are useful to highlight
190 the discrepancies that can occur amongst multiple different databases being used to answer the
191 same question in order to emphasize the importance of understanding the strengths and
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192 weaknesses to the methodology used for data acquisition when evaluating literature that utilizes
194 Limitations to this study include the inability to identify a specific patient across multiple
195 databases, which would have allowed for true measure of validity and determination of the most
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196 accurate database for analyzing THA complications. Additionally, due to the limitations of ICD-
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197 9/CPT coding and strict NSQIP definitions of comorbidities and complications, it is likely that
198 the results may be biased by imperfect matching for some variables. Lastly, the two-fold
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199 threshold used to signify an excessive clinically important difference may have missed smaller,
200 but still clinically significant, differences in the prevalence of comorbidities and complications
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following THA. This would have been more likely to occur for comorbidities and complications
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202 with a higher baseline prevalence; as this would have needed to double in order to meet the two-
fold cutoff. However, it was felt that having a higher cutoff threshold was imperative to highlight
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205 In conclusion, this study demonstrates that amongst clinical and administrative databases
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207 comorbidities and rates of complication following primary THA depending upon the database
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208 and postoperative time period used for analysis. It will be important to consider these differences
209 when critically evaluating research utilizing large databases. Additionally, in the era of value
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210 based healthcare, these differences must be considered when using large databases to develop
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213 References:
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215 1. Pugely AJ, Martin CT, Harwood J, Ong KL, Bozic KJ, Callaghan JJ. Database and
216 Registry Research in Orthopaedic Surgery: Part I: Claims-Based Data. J Bone Joint Surg
217 Am 2015;97(15):1278-87.
218 2. Pugely AJ, Martin CT, Harwood J, Ong KL, Bozic KJ, Callaghan JJ. Database and
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219 Registry Research in Orthopaedic Surgery: Part 2: Clinical Registry Data. J Bone Joint
220 Surg Am 2015;97(21):1799-808.
221 3. Bohl DD, Singh K, Grauer JN. Nationwide Databases in Orthopaedic Surgery Research. J
222 Am Acad Orthop Surg 2016;24(10):673-82.
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223 4. US Senate. HR 3590: The Patient Protection and Affordable Care Act. 2009
224 https://www.govtrack.us/congress/bills/111/hr3590/text. Accessed 2016 August 25
225 5. Centers for Medicare & Medicaid Services. CMS dry run hospital-specific report for
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226 hospital-wide all-cause unplanned readmission (HWR) measure. 2012
227 http://www.qualitynet.org. Accessed 2016 August 15
228 6. Bohl DD, Basques BA, Golinvaux NS, Baumgaertner MR, Grauer JN. Nationwide
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229 Inpatient Sample and National Surgical Quality Improvement Program give different
230 results in hip fracture studies. Clin Orthop Relat Res 2014;472(6):1672-80.
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231 7. Bohl DD, Russo GS, Basques BA, Golinvaux NS, Fu MC, Long WD, 3rd, Grauer JN.
232 Variations in data collection methods between national databases affect study results: a
233 comparison of the nationwide inpatient sample and national surgical quality improvement
234 program databases for lumbar spine fusion procedures. J Bone Joint Surg Am
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235 2014;96(23):e193.
236 8. Awad MI, Shuman AG, Montero PH, Palmer FL, Shah JP, Patel SG. Accuracy of
237 administrative and clinical registry data in reporting postoperative complications after
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238 surgery for oral cavity squamous cell carcinoma. Head Neck 2015;37(6):851-61.
239 9. Enomoto LM, Hollenbeak CS, Bhayani NH, Dillon PW, Gusani NJ. Measuring surgical
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240 quality: a national clinical registry versus administrative claims data. J Gastrointest Surg
241 2014;18(8):1416-22.
242 10. Kulaylat AN, Engbrecht BW, Rocourt DV, Rinaldi JM, Santos MC, Cilley RE,
243 Hollenbeak CS, Dillon PW. Measuring Surgical Site Infections in Children: Comparing
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249 Both Clinical Registry and Administrative Claims Data to Measure Risk-adjusted
250 Surgical Outcomes. Ann Surg 2016;263(1):50-7.
251 13. American College of Surgeons National Surgical Quality Improvement Program. Data
252 Collection, Analysis, and Reporting. . http://site.acsnsqip.org/program-specifics/data-
253 collection-analysis-and-reporting/. Accessed 2016 May 15
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255
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264 Figure 2: Breakdown of age of the patients at time of primary THA
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266 Figure 3: Prevalence of comorbidities in primary THA patients
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268 Figure 4: Prevalence of inpatient complications following THA for each database
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270 Figure 5: Prevalence of complications within thirty-days of THA for each database
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Humana Medicare parts A and B inpatient discharges registry
Definition of Procedures ICD-9/CPT codes ICD-9/CPT codes ICD-9 codes CPT codes
Definition of ICD-9 codes associated ICD-9 codes associated ICD-9 codes associated Medical records reviews
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Comorbidities/complications with reimbursement data with reimbursement data with reimbursement data by trained reviewers using
strict clinical definitions
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Time period included Inpatient and outpatient Inpatient and outpatient Inpatient only Inpatient and outpatient
for 30 days
postoperatively
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HAC: Humana administrative claims database, MED: Medicare Standard Analytic Files,NIS: National Inpatient Sample, NSQIP:
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National Surgical Quality Improvement Program , ICD-9: International Classification of Diseases, 9th Revision, CPT: Current
Procedural Terminology.
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HTN 1.03 (1.02-1.03) 1.48 (1.46-1.49) 1.42 (1.40-1.43) 1.44 (1.43-1.45) 1.38 (1.37-1.40) 0.96 (0.95-0.97)
Diabetes 1.12 (1.1-1.15) 1.94 (1.90-1.99) 2.54 (1.45-2.64) 1.73 (1.71-1.76) 2.27 (2.19-2.34) 1.31 (1.27-1.36)
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Coagulopathy 1.00 (0.96-1.05) 3.12 (2.96-3.29) 2.82 (2.59-3.06) 3.11 (3.02-3.21) 2.96 (2.75-3.18) 0.90 (0.83-0.97)
Obesity 1.16 (1.13-1.19) 1.83 (1.78-1.88) 0.60 (0.59-0.62) 1.58 (1.56-1.60) 0.52 (0.51-0.53) 0.33 (0.32-0.34)
Morbid Obesity 1.24 (1.19-1.29) 1.54 (1.48-1.62) 1.30 (1.22-1.38) 1.25 (1.23-1.28) 1.05 (1.00-1.10) 0.87 (0.83-0.91)
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Data presented as relative risk and corresponding 95% confidence interval. HAC: Humana Administrative Claims database, MED:
Medicare Standard Analytic Files, NIS: National Inpatient Sample, NSQIP: National Surgical Quality Improvement Program, COPD:
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chronic obstructive pulmonary disease, HTN: hypertension.
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Stroke 1.88 (1.51-2.33) 2.67 (2.11-3.78) 4.52 (2.91-7.03) 1.42 (1.25-1.63) 2.41 (1.62-3.59) 1.69 (1.12-2.55)
MI 1.04 (0.87-1.26) 1.51 (1.24-1.85) 2.41 (1.76-3.31) 1.45 (1.32-1.59) 2.31 (1.78-3.00) 1.60 (1.22-2.09)
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Cardiac Arrest 1.13 (0.78-1.62) 1.87 (1.27-2.76) 3.40 (2.57-6.09) 1.66 (1.37-2.01) 1.69 (1.08-2.64) 1.02 (0.64-1.62)
PE 1.37 (1.09-1.73) 1.96 (1.52-2.52) 2.39 (1.62-3.52) 1.43 (1.26-1.62) 1.75 (1.27-2.41) 1.22 (0.87-1.70)
Any SSI 3.30 (2.78-3.91) 4.00 (3.32-4.84) 5.14 (3.61-7.32) 1.22 (1.07-1.38) 5.14 (3.61-7.32) 1.28 (0.91-1.80)
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Data presented as relative risk and corresponding 95% confidence interval. HAC: Humana Administrative Claims database, MED:
Medicare Standard Analytic Files, NIS: National Inpatient Sample, NSQIP: National Surgical Quality Improvement Program, DVT:
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deep vein thrombosis, MI: myocardial infarction, PE: pulmonary embolism, SSI: surgical site infection.
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DVT 2.34 (2.17-2.53) 7.25 (6.01-8.74) 1.98 (1.66-2.36)
Pneumonia 1.88 (1.73-2.03) 8.47 (6.84-10.5) 4.52 (3.69-5.52)
Stroke 2.93 (2.57-3.34) 7.58 (5.47-10.5) 2.59 (1.90-3.52)
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MI 1.42 (1.24-1.63) 3.37 (2.63-4.34) 2.37 (1.91-2.95)
Cardiac Arrest 1.86 (1.49-2.32) 3.96 (2.57-6.09) 2.13 (1.91-2.95)
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PE 1.86 (1.63-2.11) 4.70 (3.60-6.13) 2.53 (1.98-3.21)
Wound Dehiscence 1.55 (1.28-1.86) 4.64 (3.15-6.85) 3.00 (2.11-4.26)
Deep SSI 7.08 (6.09-8.23) 2.11 (1.72-2.60) 0.30 (0.25-0.36)
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Any SSI 1.98 (1.83-2.13) 2.57 (2.28-2.91) 1.30 (1.17-1.45)
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Data presented as relative risk and corresponding 95% confidence interval. HAC: Humana Administrative Claims database, MED:
Medicare Standard Analytic Files, NSQIP: National Surgical Quality Improvement Program, DVT: deep vein thrombosis, MI:
myocardial infarction, PE: pulmonary embolism, SSI: surgical site infection.
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(height) and “weight” (weight) 40 kg/m2, Adult)
Obesity BMI 30-40 kg/m2 based upon “height” ICD-9 278.00 (Obesity [BMI from 30-40 kg/m2 ) V85.3 (BMI
(height) and “weight” (weight) between 30-39 kg/m2, Adult)
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Coagulopathy “bleeddis” (bleeding disorders) ICD-9 286.x (coagulation defect), 287.3x (primary
thrombocytopenia), 287.4x (secondary thrombocytopenia), 287.5
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Thrombocytopenia, unspecified), 269.0 (deficiency of vitamin K)
Diabetes “diabetes” (diabetes mellitus with oral ICD-9 249.xx (secondary diabetes mellitus), 250.xx (diabetes
agents or insulin) mellitus)
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Hypertension “hypermed” (hypertension requiring ICD-9 401.xx (essential hypertension), 405.xx (secondary
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medication) hypertension)
Chronic Obstructive “hxcopd” (history of severe COPD) ICD-9 491.xx (chronic bronchitis), 492.xx (emphysema),496
Pulmonary disease (chronic airway obstruction, unspecified)
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Smoking “smoke” (current smoker within one ICD-9 30.51 (tobacco use disorder, dependence)
year)
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NSQIP = National Surgical Quality Improvement Program, NIS = National Inpatient Sample, MED = Medical Standard Analytic
Files, HAC = Humana Administrative Claims database. ICD-9 = International Classification of Diseases, 9th Revision. The letter “x”
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represents all fourth or fifth digits that could designate an ICD-9 code.
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without (inferior vena cava), 453.3 (renal vein), 453.40 (deep vessel unspecified),
inflammation, vein), 453.40 (deep vessel 453.41 (proximal lower extremity), 453.42
postoperative) unspecified), 453.41 (proximal (distal lower extremity), 453.82 (deep
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lower extremity), 453.42 (distal veins of upper extremity), 453.83 (upper
lower extremity), 453.82 (deep extremity unspecified), 453.84 (axillary
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veins of upper extremity), 453.83 vein), 453.85 (subclavian vein), 453.86
(upper extremity unspecified), (internal jugular vein)
453.84 (axillary vein), 453.85
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(subclavian vein), 453.86
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(internal jugular vein)
Pneumonia “noupneumo” ICD-9 480.x (viral pneumonia), ICD-9 480.x (viral pneumonia), 481
(pneumonia, 481 (pneumococcal pneumonia), (pneumococcal pneumonia), 482.x (other
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postoperative) 482.x (other bacterial bacterial pneumonia), 483.x (pneumonia
pneumonia), 483.x (pneumonia due to other specified organism), 484.x
due to other specified organism), (pneumonia in infectious diseases
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484.x (pneumonia in infectious classified elsewhere), 485
TE
diseases classified elsewhere), (bronchopneumonia), 486 (pneumonia,
485 (bronchopneumonia), 486 organism unspecified)
(pneumonia, organism
EP
unspecified)
Stroke “ncnscva” (stroke or ICD-9 997.02 (iatrogenic ICD-9 997.02 (iatrogenic cerebrovascular
cerebrovascular accident, cerebrovascular infarction or infarction or hemorrhage), 430 (SAH), 431
C
PT
“typeintoc” (myocardial unspecified episode of care) of care)
infarction, intraoperative)
Cardiac Arrest “ncdarrest” (cardiac arrest ICD-9 427.5 (Cardiac arrest), ICD-9 427.5 (Cardiac arrest), 427.41
RI
requiring 427.41 (Ventricular fibrillation), (Ventricular fibrillation)
cardiopulmonary CPT-92950 (Cardiopulmonary
SC
resuscitation, resuscitation; eg, in cardiac
postoperative) arrest)
“typeintoc” (cardiac
U
arrest requiring
AN
cardiopulmonary
resuscitation,
intraoperative)
M
Pulmonary Embolism “npulembol” (pulmonary ICD-9 415.11 (atrogenic ICD-9 415.11 (atrogenic pulmonary
embolism, postoperative) pulmonary embolism and embolism and infarction), 415.12 (septic
infarction), 415.12 (septic pulmonary embolism), 415.13 (Saddle
D
pulmonary embolism), 415.13 embolus of pulmonary artery), 415.19
TE
(Saddle embolus of pulmonary (Other pulmonary embolism)
artery), 415.19 (Other pulmonary
embolism)
EP
Wound Dehiscence “ndehis” (wound ICD-9 998.30 (disruption of ICD-9 998.30 (disruption of wound,
disruption, postoperative) wound, unspecified), 998.31 unspecified), 998.31 (disruption of an
(disruption of an internal internal operation (surgical) wound),
C
PT
hip, with drainage (ie infection),
26990 (incision and drainage,
pelvis or hip joint area, deep
RI
abcess or hematoma), 26991
(incision and drainage, pelvis or
SC
hip joint area, infected bursa),
11981 (insertion, non-
biodegradable drug delivery
U
implant), ICD-9 80.05
AN
(Arthrotomy for removal of
prosthesis without replacement,
hip)
M
Any Surgical Site “nsupinfec” (superficial ICD-9 996.66 (infection and ICD-9 996.66 (infection and inflammatory
Infection surgical site infection, inflammatory reaction due to reaction due to internal joint prosthesis),
Postoperative)“nwndinfd” internal joint prosthesis), 998.83 (non-healing surgical wound),
D
(deep surgical site 998.83 (non-healing surgical 998.51 (infected postoperative seroma),
TE
infection, postoperative); wound), 998.51 (infected 998.59 (other postoperative infection),
“norgspcssi” (organ or postoperative seroma), 998.6 (persistent postoperative fistula),
space surgical site 998.59 (other postoperative 80.05 (Arthrotomy for removal of
EP
infection, postoperative) infection), 998.6 (persistent prosthesis without replacement, hip)
postoperative fistula)
C
prosthesis; complicated,
including total hip prosthesis,
methylmethacrylate with or
without insertion of spacer),
10180 (incision and drainage,
complex, postoperative wound
ACCEPTED MANUSCRIPT
PT
abcess or hematoma), 26991
(incision and drainage, pelvis or
hip joint area, infected bursa),
RI
11981 (insertion, non-
biodegradable drug delivery
SC
implant), ICD-9 80.05
(Arthrotomy for removal of
prosthesis without replacement,
U
hip)
AN
M
D
TE
EP
C
AC