DRUG NAME MECHANISM OF ACTION INDICATION / ADVERSE EFFECT NURSING

CONTRAINDICATION RESPONSIBILITIES

GENERIC: Second-generation cephalosporin that inhibits INDICATIONs: CV: BEFORE:

CEFUROXIME cell-wall synthesis, promoting, osmotic Pharyngitis, tonsillitis, Phlebitis, thrombophlebitis Dx:
BRAND: instability; usually bactericidal. Cefuroxime, like infection of the upper or lower a. Check for allergies.
the penicillins, is a beta-lactam antibiotic. By respiratory tracts, and skin or GI: b. Assess for anemia, renal
CLASS: binding to specific penicillin-binding proteins skin structure infection. Pseudomembraneous colitis, dysfunction
(PBPs) located inside the bacterial cell wall, it nausea, anorexia, vomiting, Tx:
THERAPEUTIC inhibits the third and last stage of bacterial cell CONTRAINDICATION: diarrhea a. Inform patient need and
ANTI-INFECTIVES wall synthesis. Cell lysis is then mediated by Contraindicated in patients importance of the drug
bacterial cell wall autolytic enzymes such as hypersensitivity to drug or other HEMATOLOGIC: to him/her.
PHARMACOLOGIC: autolysins; it is possible that cefuroxime cephalosporins Trancient neutropenia, b. Periodically assess dose.
CEPHALOSORINS interferes with an autolysin inhibitor. eosinophilia, haemolytic EDx:
anemia, thrombocytopenia a. Caution patient that
DOSAGE: SOURCE: Cefuroxime. (n.d.). hypertensitivity or
50 mg. Go.drugbank.com. SKIN: anemia may occur.
https://go.drugbank.com/drugs/DB01112 Maculopapular and erythema, b. Educate client on drug
ROUTE: urticaria, pain, sterile abscess, therapy to promote
PO, IV, IM temperarute elevation, compliance.
induration, tissue, sloughing c. Insure the patient
received the medication
as prescribed.

DURING:
Dx:
a. Asses mental status for
worsening of depression,
suicidal ideation, anxiety,
social functioning, and/or
panic attack(especially
during initiation of
therapy and when dosage
is changed
b. Monitor mood changes.
c. Monitor for adverse
effects (e.g. phlebitis,
anemia, vomiting, etc).
Tx:
a.
Establish suicide
precautions for severely
depressed patients to
decrease the risk of
overdose to cause harm.
b. Assist patient in
receiving the medication.
c. Inspect IM and IV
injection sites frequently
for signs of phlebitis.
EDx:
a. Instruct patient to
verbalize feelings and
concerns.

AFTER:
Dx:
a. Monitor for side effects.
Tx:
a. Provide safety measures
(e.g. adequate lighting,
raised side rails, etc.) to
prevent injuries.
b. Provide comfort
measures (e.g. voiding
before dosing, taking
food with drug, etc.) to
help patient tolerate drug
effects.
EDx:
a. Monitor patient
compliance to drug
therapy.
b. Instruct patient to
verbalize feelings and
concerns.