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MSC.

Zahraa hayder

Helicobacter pylori& Campylobacter


This organism was earlier known as Campylobacter pylori. It is also being incriminated as
responsible for initiating the process of metaplasia in gastric epithelium which ultimately may lead
to carcinoma of stomach. Morphology In stomach this organism takes the form of short spirals or
S shaped gram-negative bacteria which are about 3 μm long, 0.5-1.0 μm wide. H.pylori are visible
under the microscope as curved gram-negative rods . It possesses lophotrichate flagellae which are
sheathed.. Biochemical Reactions H.pylori produces catalase, urease and this enzyme as an
important determinant of pathogenicity.

Campylobacter:

Are spiral bacteria with single unsheathed polar flagellum and most species are motile.. These
organisms are non-sporing

Cultural Characters

Campylobacters microaerophilic. These fail to grow in air but require oxygen concentration of 5-
10% for their growth. Three grow at 42- 43°C and are called as thermophile organisms.

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