Department of Higher Education U.P. Government, Lucknow National Education Policy-2620 Common Minimum Syllabus for all U.P. State Universities and Colleges For First Three Years of Higher Education PROPOSED STRUCTURE OF UG CHEMISTRY SYLLABUS4s yeohrsyet 8 ( . pale 2) " Proceeding of Board of Stuiies in Chemistry ‘A meeting of the Board of Studies in Chemistry was held online on 29/5/2021. The Following members were present :- State Steering Committe Members for implementation of NEP2020 1. Prof. vimala Y, Pro-VC, Chaudhary Charan Singh University, Meerut Dr Dinesh Sharma, Ku Mayavati Govt College, Badalpur, UP Members of the Board of Studies in Chemistry of Chaudhary Charan Singh University, Meerut Prof. M.K. Gupta, Dean, Faculty of Science, Cheutthary Charan Singh Univeristy, Meerut Prof. R. K. Soni, Department of Chemistry, Chaudhary Charan Singh Univeristy, Meerut Or. Gyanendeda Singh, MMH. College, Ghaziabad Oe Sanjay Kumar Bhardwaj, SSV, Hapur Prof, RD. Kaushik, Dept of Chemistry, Gurukul Kangri University, Haridwar Prof. 5. K. Awasthi, Dept of Chemistry, University of Delhi Prof. S. P.Singh, Emeritus Professor, Kurukshetra University, Kurkshetra 110. Dr, Sulekh Chandra, Retd Principat, Zakir Hussain College, University af Delhi 12. Prof Rajlv Jain, Director, Pondicherry University err anew The committee considered the syllabus prepared by committee constituted by the UP state Government was considered and discussed, The members of the state steering committee for implementation oF NLP 2020 informed that this syllabus is minimum common syliabus is to be implemented in all the colleges and universities of the state. The committee considered the svagpsions of tie respected members of he committee and Incorporated tha sae inthe eagoaeg syllabus, The committee approved the syllabus tor implementation im the afated colleges of the Sepur | University from the session 2021-22 and onwards. The committee authorised the chairman and Ge’ convenars to make petty changes if any required in near future, fora eet @s (Prof. Mi. K. Gupta) (Prof. R. K. Soni) Oran Convenor! Faculty of Science u white VE Momundte TC es, ehey ofp Ae pred gs place ‘Te sybtehs opps! \ 6S as 2afgfal before We Preeubste Couredl 3 fr) Oe & { \\ oe we Qarvel wee \ bo \ mn 2 } VlNational Education Policy-2020 Common Minimum Syitabus for all U.P. State Universities! Colleges SUBJECT: CHEMISTRY Name Designation L Affiliation Steering Committee Mrs. Mouika 8. Gag, (LA.S.) ‘Adsitional Chief Sogtetry | Dept. of Higher Education U.P, Lucknow Chaisperson Sigering Committee Prof, Poonam Tandan Professor, Lucknow University, UP. Dept. of Physics Prof Hare Kristin Erofessar, CCS University Meerat, UP. Dept, of Statistics Dr. Ditiesh C, Sharma Associate Professor, KM. Gowt. Girls P.G, College Badslpur, G.B I Dept of Zoology Nagar, UP. Supervisory Committee-Scionce Faculty Dr. Vijay Kumar Singh | Associate Professor, Agra College, Agra Dept. of Zoology Dr. Santosh Singh Dean, ‘Mahatma Gandhi Kashi Vidbyapeeth, Varanssi Dept. of Agriculture [ Be Baby Tous Associate Professor,” Govt, Raza P.G. College Rempur, U.P. Dept, of Zoology De. Sanjay Jain ‘Associate Professor; ‘St John’s College, Agra Dept. of Stotsties Syllabus Developed by: S.No. | Name Designation Department | College/University 1. | Dr Susan VergheseP |! Associate Professor Chemistry St. John’s College, Agra and Head 2. | Dr. Mohd Kamil Hussain | Assistant Professor Chemistry Govt. Raza P.G, College Rampur, ue, 3. | Mrs. Neha Tripathee Assistant Professor Chemistry Ka, Mayawati Govt. GinlsP.G. College, Badalpur, G.B, Nagar oeSemester-wise Titles of the Papers in B.Sc. Chemistry _ Year | ‘Sem. [ Course Code | Paper Title TheoryfPructical | Credits iT Certificate in Bioorganic and Medicinal Chemistry 1 | Boor? | Fundamentats of Chemistry Theory 4 1B020102P [Quantitative Analysis Practical 2 1 | 80202017 | Bioorgaoie and Medicinal Chemisty Theory 4 BeR020F | Biuvbenical Analysis Practleal 2 | Diploma in Chemical Bynamics and Analylical Techniques 2 [om | Bo20301T | Chemical Dynamics & Caondication Chemistry Theory 4 020302? | Physical Analysis Practicat 2 1 | Boz00rt | Quantum Mechanios and Analytical Tecimiques Theory 4 18020402" | Instrumental Analysis Practical 2 Degree in Bachelor of Science 3 |v | Bor0s0rr [Organic Synthesis-A Theory 4 BO20SOZT | Rearrangemenis and Chemistry of Group Elements | Theory 4 80205037 | Qualitative Analysis Practical 2 'B020S04R | Research Project Peojeet 3 vi | B020601T | Organic Synthesis-B ‘Theory a | | Bozos0or Ghee Energetes and Theory 4 13020603" | Analytical Methods Practical 2 B020604R | Research Project Project 3 Purpose of the Program The purpose of the undergraduate chemistry program at the university and college level is to provide the key knowledge base and laboratory resources to prepare students for careers as professionals in various industries and research institutions, Program’s Outcomes 1, Students will have a firm foundation in the fundamentals and application of current chemical and scientific theories jncluding those in analytical, Inorganic, Organic aul Physical Chemistries. 2. Students will be able to design and carry out scientific experiments as well as accurately record and analyze the ceosults of such experiments. 3. Students will be skilled in problem solving, critical thinking and analytical reasoning as applied to scientific problems. 4. Students will be able to explore new areas of research in both chemistry and allied fields of science and technology. 5. Students will appreciate the central role of chemistry in our society and use this as a basis for ethical behavior in issues facing chemists including an understanding of safe handling of chemicals, environmental issues and key issues, facing oar society in energy, health and medicine. 5. Students will be able to explain why chemistry is on integral activity for addressing social, exonomic, and environmental problems, 7, Students will be able to fanction as a member of an interdiseiptinary problem solving tearn, yrPROGRAM SPECIFIC OUTCOMES (PSOS) CERTIFICATE IN BIOORGANIC AND MEDICINAL CHEMISTRY First Certificate in Rioosganic and Medicinal Chemistry will give the student a basic knowledge of all the fundamental principles of chemistry like molecular polarity , bonding theories of molecules, Periodic properties of more than 11} elements, mechanism of organic Reactions, Stercocherlstry, basle ‘mathematical concepts and computer knowledge, chemistry of carbohydrates, proteins and nucleic ‘noids: medicinal chemistry, synthetic polymers, eynthotic dyes, Student will be able to do to qualitative quantitative and biochemical analysis of the compounds in the laboratory. This certificate course is definitely going to prepare the students for varioua fields of chemistry ond wilt give an insight into all the branches of chemistry and enable onr students to join the knowledge and available opportunities related to chemistry in the government and private sector services particularly in the field of food safety, health inspector, pharmacist etc. Have a broad foundation in chemistry that stresses scientific reasoning and analytical problem solving, with a molecular perspective. Second Year DIPLOMA IN CHEMICAL DYNAMICS AND ANALYTICAL TECHNIQUES Diploma in Chemfcal Dynamics and Analytical Techniques will provide the thecretical as well as practical knowledge of handing chemicals, apparatus, equipment and instruments. The knowledge about feasibility and velocity of chemical reactions through chemical kinetics, chemical equilibrium phase equilibrium, kinetic ‘heories of Gases solid and tiquid states, coordination chemistry, metal carbonyls end bioinorgenic will enable {he students to work as chemists in pharmaceutical industries. Tae knowledge about stomic structure, quaictum mechanics, various spectroscopic tools and separation techaique will make the students skilled to work in industries: Achieved the skills required to succeed in the chemical industry Jike cement industrics, agro product, paint industries, cubber industries, petrochemica) industrics, food processing industries, Fertilizer industries, pollution monitoring and control agencies etc. Got exposures of a ‘breadth of experimental techniques using modem instrumentation, Leam the laboratory skills and safely measurements to transfer and interpret knowledge entirely in the working environment, monitoring of environment issues: monitoring of environmental pollution problems of atmospheric sciences, water chemistry and soil chemistry and design processes that meet the specified needs with appropriate ‘consideration for the public health and safety, and the cultural, societal, nd environmental considerations, Third Year DEGREE IN BACHELOR OF SCIENCE. Degtee in Bachelor of Science progremme aims (o introduce very important aspects of modern day course cutriculum, namely, chemistry of hydrocarbons, alcohols, carbonyl compounds, carboxylic acids, phenols, amines, heterocyclic compounds, natural products main group elements, qualitative analysis, Separation techniques and analytical techniques. It will enable the students to understand the importanes of the elements in the petivdie lable ineluding their physical and chemical nature and role in the daily life and also to understand the concept of chemistry to interrelate-and interact fo the other subject like mathematics, physics, biological science etc. ~ Upon completion of a degree, chemistry smdenis are able 10 employ critical thioking and scientific inguity in the performance, design, interpretation and documentation of laboratory experiments, at a level suitable to succeed at an eritcy-level position in chemical industry or a chemistry graduate program ‘Various researoh institutions and industry people in the pharmaceuticals, polymers, and food industry sectors will surely value this course, a 4Set emir Toor on Year| sem | Theory Units Practical Units Research | rthe Paper Paper Project | gihjecr , 1 eal ental ae se pl ‘Quantitative | 1, Water Quality analysis: Nil A= 6 Wessany | wentnenee = eae mo | Simple Honing theres of Serre areca Wot ie 3 Eaination osc | neta eit Sanco 4. Recapitelation of basics of Esumavon ot inorganic Gott Coeaeeyt okie Meni of Cai Reon C terobaaily 7. Basic Computer system (in hay occa icp Se L —— 4 T ) Bengatcl | Lemmy afcuuanim | bedama | Galas ma te (wae SiSicinl | 2 chemies ofbotes tee ea: cooly | Texeausreeies aus |” sagan [i ateeemtae 4. Introductory Medicinal 2. Qualitative and = eave Some Seema 6. Introduction to Polymer acids and Fots ‘7. Kinetics and 3. Determination and ages inane i Polymerization 8, Acids 4. Synthesis of Syathetic Dyes simple drag molecules. 2 | om | chewed | j.chenetincis Teysat | Lérastectsoinn | ma | sane Drones & | 2 Chea tam fee | 2 Suite touen Coontaton | 3a Equa piven Gamay” | Leber at nt Teds) Boa Son en £ GaationChmiy eerie ‘thew ofChrlnton Saute Gomi | Ce brn ad aon |) Gein | tame tee Tosranant | 1 MoleurWagn | wa | a6 cee} gamete | aa gmr pee poner n|\amee cae | aa ee | oe SA Sauna ad EAs end Army ‘aeceram at vices anal 3, Separation of organic Mistare 4. Identification of organic compounds ee1. Rearrangements 2. Catalysis 3. Chemistry ofthe ‘Maln Group Elements 4. Chemistry of ‘Transiion Blements S. Chemusty of Lanthamdes 6. Chemistry of Actinides 7. Mer Carbonyls 8, Bicinocganie Chemistry MI Organic Synenesis-B A Reagente'io Organie synthesis 2. Organornetatlic Conspounss 4. Aldebydes and Ketones. 4. Carboxylic cits and tir Fustionat Derivatives 5. Onganie Synthesis wia Brosares 6. Organic Compounds of Niteogen 7. Heterosyclie Compounds 28 Natural Products Aralytical Methods 1. Gravimetric Analysis 2. Paper Chromatography 4 Thin syer ‘Chromatography 4. Thermochemistry Project 4243 “3 Chemical Energetics and Radiochemiste 1. Thecmodynamioe-T 2 Themodynamice 3. Electrochemistry 4 lone Bguiibriom 5. Phoo Cbemisry 6 Colligosive Propetes of Sonticas 2 Surface Cromisey 8 Radiocheaisty| course SUBJECT; CHEMISTRY Total Credits vf the Year Se Paper Title Prerequisite for Elective Hous | subject m, Paper For Major Subject | per Semester certttteate | 1 | theory Fundamentals of ‘Chemisty in Yes 0 4 in Chemistry 128 Open to all Bloorganie and Medicinal Practical | Quantitative Analysis Chemistcy in Yes 0 2 ‘Chemistry 1 me Open to all © | Theoty-t Bioorganic and Passed Sem-, y Yer 60 4 ' Medicinal Theory paper- | Zoo/Bot/Physics/ Chemistry 1 ‘Math/Comp Sci Pracical-2 | Biochemical Analysis | Opted Sell, ‘Yes 60 2 ‘Theory Ppoer- | ZooBot Physics! 1 Matb/Comp Sci. Diploma in | il | Theoty-t | Chemicat Dynamics & | Chemistry in Yes 60 4 Chemical Coordination Chemistry | 12" ZooiBor/Physies! Dynnaice Physios in ‘Math/Comp Sci. ond 128 Analytical echniques Pracicals2 } —Physicat Analysis ‘Opted Semi, Yes 0 2 Theory Ppacr-i | Zoo/Bot Physics! ‘MathiComp Sci. Iv] ‘Theoty-1 ] Quantam Mechanics and } Chemistry in Yes 0 4 ‘Analytical Techniques 1 ZooiBot Physics! Math’Comp Sci Practical Tnstramental ” Chemistry in Yes 60 2 2 Analysis 1s ‘Loo Bot /Physies! ‘Math/Comp Sci. Degreein | V | Theory-1 | Organic Syothesis-A | Passed SemI, Yes 60 4 Riachetor of Theory paper | Zoo/Bot Physics! Seience Math/Cownp Sci. ‘Theory-) | Rearrangements and | Passed Semmt, Yes 0 4 Chemistry of Group | Theory paper | Zoo/ftot /Physies/ Blements ‘Math'Comp Sci Practical} Qualitative analysis, Opted Sem-V Yes 0 2 3 Theory Ppser-1 | Zoa/Bot/Physics! #2. Math. os"Research 45 Project Vi | Theo! | Organic Syathesis-3 | Passed Som-V Yes 60 ‘Theory paper-| | Zoo/Bot/Physics! Math ‘theory-1 | Chetaical Energetics Cemsry oa Yes wo and 15 Zoo/Bot/Physics! Radiochemistry Physics in 128 | Matl/Comp Sei, Practical | Analytical Methods | Chemistry in Yes 60 3 128 Zox/BousPhysics! Math/Comap Sci. Research oon 45 Project -Teale 5 Year | Sem.) Course Code) Paper Title ‘Theory/Practical | Credits Certificate in Bioorganic and Medicinal Chemistry “ Py o2MINT — | Findamenials of Chemistry Theory 4 je poz0102P — | Quantitative Analysis Practical 2 1 ja 80202017 — | Bioorganic and Medicinal Chemistry Theory 4 020202P | Biochernical Anatysis Practical 2Semester-1, Paper-i (Theory) Course Title: Fundamentals of Chemistry _ in | 4 Semester: First Programme/Cless: Certificate in Year: First . ester: First Bioorganic and Medicinal Chemistry Paper-1 ‘Theory Subject: Chemistry ‘Courye Code:B020101T- ‘Course Title: Fundamentals of Chemistry, Conrae outcomes: ; - ‘There is nothing more fandamental to chemistry than the chemical bond. Chomival bonding is the language of logic foq ‘chemists. Chemical bonding enables scientists to take the 100-plus elements of the periodic table and combine them in my ‘ways to form chemical compounds and materials, Periodic trends, asising from the arrangement of the periadic table, provide| chemists with an invaluable tool to quickly predict an element's properties. These trends exist becouse of the similar alomi structure of the elements within their resgective group families or periods, and because of the periodic nature of the elements Reaction mechanism gives the fundamental knowledge of carrying out an organic reaction in a step-by-step soanney. This) course will provide « broad foundation in chemistry that stresses scientific reasoning and analytical problem solving with a molecular perspective, Students will gain an understanding of + Molecular geometries , physical and chemical properties of the molecules. + Current bonding models for simple inorganic end organic motecuies in order to predict structures and important bonding parameters. + The chapter Recapinutation of basics of organi chemistry fives the most primary and utmost important knowledge and concepts of organic Chemistry + This course gives a broader theoretical picture in multiple stages in an overall chemical reaction. It describes. reactive intermediates , transition states and states of al the bonds broken and formed enables to understand the reactants, catalyst, steriochemistry and majot and minor products of any organic reaction. 1t deseribes the types oF reactions and the Kinetic and thermodynamic aspects one should koow for carrying out any ‘enetion and the ways how the reaction mechanism ean be determined. + The chapters Steriochemistry gives the clear picture of two-dimensional and three-dimensioual structure of the ‘molecules, and their role in reaction mechanism, Credits: 4 Compulsory ‘Max. Marks; 25+75 Min. Passing Marks:...... Total No. of Lectures ~ 60 ‘Unit I ‘Topics No, of Lectures I Introduction to Indian ancient Chemistry and contribution of Indian Chemists, in context to the 10 holistic development of modern science and technology, should be inctuded under Continues LL Evaluation (CLE) er 10Molecular polarity and Weak Chemical Forces : ‘Resonance and resonance energy, formal charge, Van der Waals forces, ion-dipote forces, dipote dipole interactions, induced dipole intornotion, dipole moment ard molecular Structure (Dintomic and polyatomic motecules), Percentage ionic character from dipole moment, polarizing power and polarizability. Fajan’s rules and corsequences of polarization. Hydrogen bonding, van der Waals forces, jon-dipole forces, dipole-dipole interactions, induced dipole interaction, ‘Simple Bonding theories of Molecules ‘Atomic orbitals, Aufbau principle, multiple bonding (« and x bond approach) and bond Lengths, th valence bond theory (VBT), Concept of hybridization, hybrid orbitals and molecular geometry, Bent’ cule, Valence shell electron pair repulsion theory (VSEPR), shapes of the following simple molecuies and) {ons containing lone pairs and bond pairs of electrons: HO, NHs, PCls, SFe, SFs CIF: Is, and H3O*, Molecular orbital theory (MOT). Molecular orbital diagrams bond orders homonuclear and heteronuclear diatomic molecules and ions (N2, O2, C2, Bz, Fz, CO, NO, and their ions) Periodic properties of Atoms (with reference to s & p-block) Brict discussion, factors affecting and variation trends of following properties in groups and periods | ing effect, Slater rules, Atomic and ionic radit| Electronegstivity, Pauling’s/ Allred Rochow's scales, ionization entholpy, Electron gain enthalpy. fective ucleat charge, shielding or sore 05 Vv Recapitulation of basies of Organic Chemistey: Hybridization, boud lengths and bond angles, bond| energy, localized and delocalized chemical bonding, Van der Waals interactions, inclusion compounds CClatherates, Charge transfer complexes, lypervonjugation, Dipole moment; Electronic Displacements Inductive, electromeric, resonance mesomeric effects and theit applications 05 vi Mechanism of Organic Reactions: Curved arrow notation, drawing electron movements with allows, half-headed and double-headed arrows, homolytic and heterolytic bond fission, Types of reagents -| lectrophiles and nucleaphiles, Types of organic reactions, Energy considerations. Reactive intermediates ~ Carbocations, carbenions, free radicals, carbenes, arynes and nitrenes (with examples). Storeochemistry (To be taught with demonstration of Molecular models in the classroom teaching) Concept of isomerism, Types of isomerism; Optical isomerism — elements of symmetry, molecular chirality, enantiomers, steroogenic conter, optical activity, properties of enantiomers, chiral and achiral molecules with two stereogenic centers, disasteromers, threo and erythro diastereomers, steso compounus, resolution of enantionmer, inversion, retention aad recemization. Relative and absolute configuration, sequence mules, D & Land R & $ systems of nomenclature. Geometric isomerism ~ determination configuration of geometric isomers, E & Z system of nomenclature, geometric hromerism in oximes alicyclic compounds. Conformational isomerism — conformational analysis of ethane and n-butane} conformations of cyclohexane, axial be LL 10 10Tana ‘equatorial bonds, conformation of mono substituted cyclohexane derivatives, Newman projection and} Sawhorse formulae, Fischer and flying wedge formulae, Difference between configuration and! conformation. ‘Vil | Basic Computer system (in brief}-Hardware and Software; Input devices, Storage devices, Output devices, Central Processing Unit (Camtrot Unit and Arithmetic Logic Unit); Number syotom (Binary, Octal and Hexadecimal Operating System), Computer Codes (BCD and ASC! NamerioSring| constants and variables. Operating Systems (DOS, WINDOWS, and Linus); Introduction of Software| 05 languages: Low level and High Level languages (Machine language, Assembly language; QBASIC| FORTRAN) Software Products (Office, chemsketch, scilab, matlab, hyperchem, etc.), internet application, | ‘VIIt | Mathematical Concepts for Chemistry Logatithmic relations, curve sketching, linear graphs and coleulation of slopes, differentiation of functions) 95 like Kx, 0% X*, sin x, log x; maxima and minima, partial differentiation and seciptocity relations| Integration of some useful/relevant functions; permutations and combinations, Pactorials, Probability Suggested Readings: 1. Lee, TD. Concise Inorganic Chemistry, Pearson Education 2010 2. Hubecy, IE, Keiter, E.A., Keiter, R. L, Medti, O-K. Inorganic Chemistry, Principles of Structure and Reactivity, Pearson Education 2006. 3. Douglas, B.E. and Mc Daniel, D-H., Concepts & Models of Inorganic Chemistry, Oxford, 1970 4, Shriver, D.D. & P. Atkins, Jnorganic Chemistry 2nd Ed., Oxford University Press, 1994 5. Day, MC. and Selbio, J. Theoretical Inorganic Chemistry, ACS Publications 1962, 6, Singh J, Yadav L.D.S, Advanced Organic Chemistry,Pragati Edition 7, Morrison, R.N. & Royd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt, Ltd. (Pearson Education). 8. Carey, F.'A., Guiliano, R, M.Organic Chemisury, Bighth edition, McGraw Hill Education, 2012. 9. Loudon, G. M. Organic Chemistry, Fourth edition, Oxford University Press, 2008. 10. Clayden, J,, Greeves, N. &Warren, S. Organic Chemistry, 2vedition, Oxford University Press, 2012. 12, Grabamn Solomons, T-W., Fryhle, C. B. Organi¢ Chemistry, Joba Wiley & Sons, Ine. 12. Sykes, P. A guidebook to Mechanism in Organic Chemistry, Pearson Education, 2003 13, Frantis, P. G. Mathematics for Chernists, Springer, 1984 14, Mukehefii, Singh, Kapoor, Organic Chemistry , Voi 1, New Age International 2014 45. R.L.Madan, CHEMSITRY FOR DEGREE STUDENTS AS PER CBCS SEM 1, S Chand 16.Sonia Ratnani .Shriniwas Gurjar | Sheetal Budhirajana, Chemistry (Inorganic & Organic) Volume-t, Manakin press: 17, TN SRIVASTVA AND PC KAMPOJ, SYSTEMATIC NALYTICAL CHEMISTRY, SHOBAN LAL NAGIN| ‘CHAND Note: Por the promotion of Hind! language, course books publishes Suggested onfine links: Intepz/Mheecontentiupsdc.gov.in/Home.aspx ‘ttoss/npte se.in/oourses/s04/106/204106096) intep://heecontent.upsde.gov.in/Hlome.aspx Hindi may be presoribed by the University tl inf $0907 18 ‘This course is compulsory for the students of following subjects: Chemistry in 12 Class oe" 2valuated on the basis of score obtained in a mid-term exam, together with the performance of other activities Which can include short exams, in-class ‘of on-line tests, home assignments, group discussions or oral presentations, among others . Or Aasegamentt and presentation of Assignment 10 masks) (04 tests (Objective). Max marks ofeach test = 10 (10 marks) {average of al 04 tests) Overall performance throughout the semester, Discipline, {05 marks} porticipation in different activities) Course prerequisites: To study this course, a student niust have had the chemistry in class 12" [Suggested equivalent online courses:Semester-I, Paper-2 (Practical) Course Title: Quantitative Analysis Programme: Certificate in Year: First ‘Semester. T Bioorganic and Medicinal ‘Chemistry Practical paper-2 ‘Subject: Chemistry Conse Code-Bozot0z? | Course Tite: Quantitative Analysis ‘Course outcomes: Upon completion of this course the stdents will have the knowledge and skills to; understand the Inboratory methods and tests related to estimation of metals ions and estimation of acids and alkali contents in commercial products. ~ Potability tests of water samples. + Estiouation of metal ions in samples + Estimation of alkali and acid contents’ in samples + Estimation of inorganic salts and hydrated water in samples Credits: 2 Elective Max. Marks: 25+75 = 100 ‘Min, Passing Marks: Practical 60.6 Unit Topies No of Lectures 1 | Water Quatity anatysis 16 {. Estimation of hardness of water by EDTA. 2, Determination of chemical oxygen demand (COD). 3, Determination of Biological oxygen demand (BOD). [ I} 2stimation of Metals fons - 4 |. Estimation of ferrous and ferric by dichromate method, 2, Estimation of copper using thiosulphate. IL | Bhtimation of acigs and alkali contents 4 |. Determination of acetic avid in commercial vinegar using NaOH. 2 Determination of alkali content —antacid tablet using HCL 3. Estimation of oxalic acid by titrating it with KMnOs. 1V | Estimation ofinorgante salts and hydrated water 16 1. Estimation of sodium carbonate and sodium hydsegen carbonate present in @ mixtuce, 2, Estimation oF calcium content in chalk as caleium oxalate by permanganometry. 3. Bstimation of water of crystallization in Mo's salt by titrating with KMaOx. oo “‘Suggested Readings: T. Mohan, J. Vogel's Quuniative Cheascal Analysts, Person, 2009, 2. Harris, D. C. Quantitative Chemical Anatyss. 6th Bd., Freeman (2007) Chapters 3-5. 3. Harris, D.CExploring Chemical Analysis, 9isEd. New York, W.H. Freeman, 2016. 4. Khopkar, S.M. Basic Concepts of Analytical Chemistry. Now Age lnternational Publisher, 2009. 5. Skoog, D.A. Holler F.J. and Nieman, T.A. Principles of Instrumental Analysis, Cengage Learning India Bdition Note: For the promotion of Hindi language, course books published in Hindi may be prescribed by the University Suggestive digital platforms web links 6, https:/wyrw, labster,com/chemistry-virtual-labs/_ 7. itosdl swe stab 0 ibroad-arca-chemical-sciences 8, hittp://chemeollective.org/vlabs ‘This course can be opted as an elective by the students of following subjects: Chemistry in 12 Class Suggested Continuous Evaluation Methods: Viva voce (10 marks) Mock test al (10 marks) Overall performance (OSmiarks) Course prerequisites: To study this course, a student must have had the chemistry in 22 Cass ‘Suggested equivalent online courses: Further Suggestions:or Semester-II Paper-1 Course Title: Bioorganic and Materials Chemistry_ Programme: Certificate in Year: | Semester: IL Bioorganic and Medicinal Chemistry Paper-1 Blective Subject: Chemistry Course auton important biochemical reactions in living organisms. When studying biomolecules, one can understand the physiological function] that regulates the proper growth and development of a human body. ‘This course aims 10 introduce the students with basic exporimental understanding of carbohydrates, amino acids, proteins, nucleic acids and medicinal chemistry. Upon completion o: this course students may get job opportunities in food, boverage and pharmaceutica? industries. Course Code: BO20201T —_| ‘Course Title: Bisorganic and Medicinal Chemistry jomoléenles are important for the functioning of living organisms, These molecules perfo rm. oF trigge Credits: 4 Elective Max. Marks: 25475 Min, Passing Marks: C Total No. of Lectures = 60 Unit Toptes . No. of to Lectures Chemistry of Carbohydrates = Classification of carbohydrates, reducing and nop-reducing sugars| Genctal Properties of Glucose and Fructose, their open chain structure, Epimers, rautarotetion and nomers, Mechanisa of mutarotation Determination of configuration of Glucose (Fischer's proof). Cyc stuchure of glucose. Haworth projections. Cyctic structure of fructose. Inter conversions of sugary (esconding and descending of sugar series, conversion of aldoses to Ketoses). Lobry de Bruyn-van Ekenstein rearrangement; stepping~up (Kiliani Fischer method) and stepping-down (Ruff’s &Woht's methods) of aldoses; end-group interchange of aldoses Linkage between monosachharides, structure of disachatrides (sucrose, maltose, lactose.) m Chemistry of Protelns: Classification of amino acids, cwitter ion structure and Isoelectric. point. Overview of primary, secondary, tertiury and quaternary structure of proteins. Determinatioa of primary stracture of peptides, determination of N-terminal amiao acid (by DNEB and Edman method) and C- terminal amino acid (by thiohydantoin and with carboxypeptidase enzyme). Synthesis of simple peptides (upto dipeptides) by N-protection & C-activating groups and Merrifield solid phase synthesis. Protein) denaturation’ renaturation Mechanism of enzyme action, factors affecting enzyme action, Coemzymnes and cofactors and their role in biological reactions). Chemistry of Nucleic Acids: Constituents of Nucleic acids: Adenine, guanine, thymine and Cytesine (Structure only), Nucleosides and nucleotides (nomenclature), Synthesis of nucleic 0s . or 16acids, Structure of polynucleotides; Structure of DNA (Watson-Crick model) and RNA (types of RNA)| Genetic Code, Biological roles of DNA and RNA: Replication, Transcription and Translation Introductory Medicinal Chemistry : Drug discovery, design and development, Basie Retrosyatheti approseh. Drug action-receptor theory. Structure ~acti ~OH group,-Niir group, dauble bond and aromatic ring. Mechanism of action of the representative drugs} of the following classes: analgesics agents, antipyretic agents, anti-inflamunatory agents. (Aspitin, paracetamol); antibiotice (Chloramphenicol); antibacterial and antifiangol ogonts (Sulphonomistes Sulphanethoxazol, Sulphacetamide); antiviral agents (Acyclovic), Central Nervous System agents (Phenobarbital, Diazepam),Cardiovesoular (Glyceryl trinitrate), HIV-AIDS related drugs (AZT Zidovudine relationships of drug molecutes, binding role o' Solid State Definition of space lattice, unit cell. Laws of crystallography ~ (i) Law of constancy of interfacial angles Gi) Law of rationality of indices and iti) Symmetry etements in crystals and law of symmetry X-ray diffraction by crystals. Derivation of Bragg equation. Determination of crystal structure of NaCl, KCI and) CSCI (powder method), Introduction to Polymer Monomers, Oligomers, Polymers and their characteristics, Classification of polymers : Natural synthetic linear, ross linked and network; plastics, elastomers, fibres, Homopolymers and Ce-polymers, Bonding in| polymers : Primary and secondary bond forces in polymers ; cohesive energy, and decomposition of polymers. Determination of Molecular mass of polymers: Number Average motecular mass (Mn) and) Weight average molecular mass (Mw) of polymers and determination by (3) Viscosity (li) Light scattering| method (ii) Gel permeation chromatography (iv) Osmametry and Ultracentrifuging, Silicones and Phosphizenes Silicones and phosphazenes as examples of inorganic polymers, nature of bonding in triphosphazenes. 10 va Kinetics and Mechanism of Polymerization Polymerization techniques, Mechanism and kineties of copolymerization,Adgition or chain growth polymerization, Free radical vinyl polymerization, ionic vinyl polymerization, Ziogler Natta, polymerization and vinyl polymers, Condensation or step growth-polymerization, Polyesters, polyamides, phenol formaldehyde resins, urea formaldchydc resins, epoxy resins and polyurethanes. as var Synthetic Dyes: Colour and constitution (electronic Concept), Classftcation of dyes, Chemistry and| synthesis of Methyl orange, Congo red, Malachite green, crystal violet, phenolphthalein, fluorescein, ‘Alizarin and Indigo. 05 ow vSuggested Readings: 1. Davis, B. G., Fairbanks, A. J, Carbohydrate Chemistry, Oxford Chemistry Primer, Oxford University Press. 2. Finar, LL. Organic Chemismry (Volume 2), Dorling Kindersicy (ladia) Pvt. Ltd.(Pearson Education). 3. Nelson, D. L. & Cox, M. M. Lehninger’s Principles of Biochemistry 7th Ed., W. Hl, Freeman. 4. Berg, 3.M., Tymoceke, J. L. & Stryer, L. Blochemisiry 7th Ed, W. H. Freeman, 4. Morrison, R. T. & Boyd, R. N. Organte Chemlstry, Dorling Kindersley (India) Pvt. Ltd. (Pearson Education). 66. Patrick, G. L. Inteoduction ‘o Medicinal Chemistry, Oxford University Press, UK, 2013. 7. Singh, H. & Kapoor, V.K. Medicinal and Pharmaceutical Chemistry, Vallebh Prakeshan, Pitampura, New Delhi, 2012, . 8. Atkins, P. W. & Paula, J. de Atkin's Physical Chemistry Ed, Oxford University Press 13 (2006). 9 Bah, DW Physleal Chenalsny Thinsin Press, Ta (20097) 10. Castellan, G. W. Physical Chemistry 4th Ed. Narosa (2004). ILRB. Seymour & C.E, Catraher: Polymer Chemistry: An Introduction, Marcel Dekker, Inc. New York, 1981. 12. G. Odian: Principles of Polymerization, 4°Ed. Wiley, 2004 13, RW. Billmeyer: Textbook of Polymer Science, 2Bd, Wiley Interscience, 1971. 14.P. Ghosh: Polymer Science & Technology, Tata McGraw-Hill Education, 1991 15. Mukhegji, Singh , Kapoor, Organic Chemistry, Vol 3, New. Age International 46. B.KSharma, Polymer Chemistry, Krishna Publications 47.0L Jain , Sunjay Jain & Nitin Jain, Fundamentals of Biochemistry, S$. Chand Publishing 18. TN SRIVASTVA AND PC KAMPO, SYSTEMATIC NALYTICAL CHEMISTRY, SHOBAN LAL NAGIN CHAND Note: For the promotion of Hindi language, course books published in Hindi may be prescribed by the University Suggested online links: M/ scl. ‘ttp://heecontent.upsdc.gov.in/Home.aspx ‘httpss//mpte.ne,in/eourses/104/105/104105124/ ‘https: //nptel.ac,in/courses/103/106/105106204/ hetps://nptel.ac.in/courses/104/105/104108034/ ls 104/103/104 di i 4102/1 buips:/nptel.ac.t /104/106/1041061 impel ac in/coursess/ 104 120 ‘This course can be opted as an clective by the students of following subjects: Chemistry in 12" Class Suggested Continuous Evaluation Methods: Assessment and presentation of Assignment (40 marks) (04 Unit tests (Objective): Max marks of cach unit test= | (10 marks) 10 (average of all 04 unit tests) ‘Overall performance throughout the semester (05 marks) (Discipline, participation in different activities) Course prerequisites: To study this course, a student must have Passed Sem-1, Theory paper-1 Suggested equivalent online courses: Parther Suggestions 18.Semester-It , Paper-2 (Practical) Course Title: Biochemical Analysis Programme: Certificate Year: 1 Semester: in Bioorganic and Medicinal Chemistry Subject: Chemistry Course Coder Bar7H7P | Course Tithe: Biochemical Analysis Course outcomes: This course will provide basic qualitative and quantitative experimental knowledge of biomolecules such as carbohydrates, proteins, amino acids, nucleic acids drug molecules. Upon successful completion of this course students ray get job opportunities in food, beverage and pharmaceutical industries. = Ti mae Max. Marks: 25+75 = 100 l Min, Passing Marks’ Practical 60-h Unit Topics Noot Lectures 1 | Qualitative and quantitative analysis of Carbohydrates: . 8 1. Separation of a mixture of two sugars by ascending paper chromatography 2. Application of TLC and PC for the identification of natural coloring materials such as Lycopene from Tomato and Chlorophyit from Spinach 3, Differentiate between a reducing/ non reducing suger 4. Synthesis of Osazones. I ‘Qualitative and quantitative analysis of Proteins, amino acids and Fats | mw Isolation of protein. 2, Determination of protein by the Biuret reaction. 3. TLC soparation of a mixture containing 2/3 aminu acids 4. Paper vhrorsatographic separation of a mixture containing 2/3 amino acids 5. Action of salivary amylase on starch 6. To determine the concentration of glycine soluti 7. To determine the saponification value of an oil/fat. 8. To determine the iodine value of an oilfat by formylation method, ML | Determination and identification of Nucleic Acids 2 1, Determination of nucleic acids 2. Extraction of DNA from onion/ennliflower 1V__| Synthesis of Simple drug molecules % + 1, To synthesize aspirin by acetylation of salicylic acid and compare it with the ingredient of an aspirin tablet by TLC. 2, Synthesis of barbituric acid 43. Synthesis of propranololSuggested Readings: 1, Fumiss, B.S; Hannaford, A.J; Smith, P.W.G; Tatchell, A.R. Practical Organic Chemistry, 5th £d., Pearson (2012). 2, Mann, F.G, & Saunders, B.C. Practical Organic Chemistry, Pearson Edueation. 3, Vogel's Qualitative Inorganic Analysis, Revised by C. Svebla, 4. Vogel, Ail. A Textbook of Quantitative Analysis, ELBS, 1986 5. Furniss, B.S.; Hannaford, A.J Rogers, V.; Smith, P.W.G.; Tatchell, A.R. Vogel's Textbook of Practical Organic Chemistry, ELBS. 6. Abluvalia, V.K. & Aggarwal, R. Comprehensive Practical Organic Chemisiry,Universities Pres 7. Cooper, T.G. Tool of Biochemistry, Wiley-Blackwell (1977). 8, Wilson, K. & Walker, J. Practical Biochemistry. Cambridge University Press (2009). 9. Varley. H. Gowenlock, AH & Bell, M.: Practical Clinical Biochemistry, Heinemann, Note: For the promotion of Hind: Janguage, cowse books published in Hlindi may be preseribed by tho University Suggestive digital platforms vweeb Inks ‘This course can be opted as an elective by the students of following subjects: Chemistry in 12" Class Shygested Continuous Evaluation Methods: Viva voce (10 marks) Mock test (10 marks) Overall performance (Osmarks) ‘Course prerequisites: To study this course, a student must have Opted Sem, Theory Paper-. Suggested equivalent online courses: - { Purher Suggestion 20Year] Sem. | Course Code] Paper Titte ‘Theory/Practical | Credi Diploma in Chemical Dynamics and Analytical Techniques 2 | | woamanrt | chemical Dynanies & Theory 4 Conran Chemiry 020302" | Phin Anais ractical z | ooseat | Quanam Mechanics and Thecry a ‘Annlycal Tecigns — 2 poz0acze | tsumenalAnajis Practical Z 21Semester IM], Paper-1 (Theory) Course Title: Chemical Dynamics & Coordination Chemistry Programme: Diploma in Chemical ‘Year: Two | ‘Semester: SLL ‘Dynamics and Analytical "Techniques Paper-1 Theory Subject: Chemistry Course Code:B020301T ‘Course Title: Chemical Dynamics & Coordination Chemistry ‘Course outcomes: Upon successful completion of this course students should be able to describe the characteristic of the three states of matter and desenbe the ditierent physical properties of each state of matter. kinetic theory of gases, laws of crystallography , liquid state and liquid crystals, conductometric, potentiometric, optical methods polarimetry and spectrophotometer technique to study Chemical kinetics and chemical Equilibrium. After the) completion of the course, Students will be able to understand .metal- ligand bonding in transition metal complexes) thermodynamic and kinetic aspects of metal complexes. Credits: 4 Elective ‘Max. Marks: 25+75 © ‘Min, Passing Marks: ‘Total No, of Lectures = 60 Unit Topics No. of Lectur 6 1 | Chemica} Kinetics Rate of a reaction, molccularity and order of reaction, concentration, dependence of rates, mathematical characteristic of simple chemical reactions — zero order, Sirs order, second order, pseudo order, haif-ife and mean jie. Determination of the order of reaction] ~ differential method, method of integration, halflife method and isolation method. ‘Theories of chemical kinetics: Effect of temperature on rate of reaction, Arrhenius equation| —'@ concept of activation energy. Simple collision theory based on hard sphere model, transition state| thoory (equilibrium hypothesis). Expression for the rate constant based on equilibrium constant and thermodynamic aspects (no derivation . I | Chemical Bquitibrium : Equilibrium constant and free energy, thermodynamic derivation of 3 ‘aw of mass action. Le-Chateliers principle. reaction isotherm and reaction isochore - Clapeyron Clausius equation and its applications, I | Phase Kquitibriom : Statement aad meaning of the cerms-phase, component and degree of freedom, derivation of Gibbs phase rule, phase equilibria of one component system- water, CO» | 05 and systems, Phase equilibria of two component systems ~ Solid - liquid equilibria, simple eniectic ~ Bi-Cd, Pb Ag systems.Kinetic theories of gases Gaseous State: Postulates of ki ‘Waals equation of state. theory of gases, deviation from ideal behavior, van det Critical phenome : PY isotherms of real gases, continuity of states, the isotherms of Van det ‘Waals equation, relationship between critical constants and Van der Waals constants, the law of comesponding states, reduced equation of state. ‘Molecular Velocities: Qualitative discussion of the Maxwell's distribution of molecular velocities, collision number, mean free path and collision diameter, 10 Liquid State Liquid State: Intermolecular forces, structure of liquids (a qualitative description). Structural differences between solids, liquids and gases. Liquid erystals: Difference between liquid crystal, solid and liquid, Classification, structure of nematic and cholesterol phases. Liquids in sods (gels): Classification, preparation and properties, inhibition, general application vi Coordination Chemistry Wemer's theory of coordination complexes, classification of ligands, ambidentate ligands chelates, coordination numbers, IUPAC nomenclature of coordination complexes (up to two! metal centers), Isomerism in coordination compounds, constitutional and stereo isomerism, ‘geometrical and optical isomerism in square planar and octahedral complexes, vir ‘Theories of Coordination Chemistry | Metat- ligand bonding in transition metal complexes, limitations of valance bond theory, an elementary idea of erystal field theory, crystal field splitting in octahedral, tetrahedral and square planner complexes, Jobn teller effect, factors affecting the crystal-ield parameters, Il. Thermodynamic and kinetic aspects of metal complexes: A brief outline of daermodynamic stability of metal complexes, concept of hard ati soft acids and bases and factors affecting the stability, stability constants of complexes and their determination, substitution reactions of square planar complexes 10 vit Tnoryante Spectroscopy and Magnetism 1)Electronie spectre of Transition Metal Complexes ‘Types of electronic transitions, selection, rules for d-d transitions, spectroscopic ground states spectrochemical series, Orgcl-energy level diagram for di and d9 states, discussion of the electronic spectmam of [Ti(H20).)"* complex ion, 1)Magnetic properties of transition metal complexes, types of magnetic behaviour, methods of determining magnetic susceptibility, spin-only formls, L-S coupling, correlation of 4 s and q eff 10 of 2Br 5 " ‘values, orbital contribution to magnetic moments, application of magnetic mament data for 34- ‘metal complexes, ‘Suggested Readings: 1. Atkins, P, W. & Paula, J, de Atkin’s Physical Chemistry Bd., Oxford University Press 13 (2006). 2, Ball, D, W. Physical Chemistry Thomson Press, India (2007). 3. Castellan, G. W. Physical Chemistry 4th Ed. Narosz (2004). 4. Cotton,F.A, Wilkinson,G and Gaus,P. L Basic Inorganic Chemiatry,3 Edition ,Wiley 1995 5. Lee,5.D, Conelse Inoiganle Chenlstty 4 Editlou ELBS,1977 66 Douglas,B, McDaniel ,D and Alexander,J ,Concepts of Models of Inorganic Chemistry, Jobn Wiley & Sons; 3rd edition , 1994 7. Shriver,D.E Atkins,P.W and Langford,C H , Inorganic Chemistry Oxford Univessity Press, 1994. & Porterfield ,W.W, Inorganic Chemistry ,Addison Wesley 1984. 9. Sharpe,A .G, Inorganic Chemistry, ELBS,3®® edition ,1993 10. Miessler,G.L,Tarr,D.A, Inorganic Chemistry, 2™ edition , Prentice Hall,2001 11, Babl and Bahl, Essential of Physical Chemistry, S.Chand 12. R Gopalan & V Ramatingam, Concise Coordination Chemistry, Vishal publishing house J3.TN SRIVASTVA AND PC KAMPOI, SYSTEMATIC NALYTICAL CHEMISTRY, SHOBAN LAL NAGIN CHAND ‘Note: For the promotion of Hindi language, course books published io Hindi may be prescribed by the University Suggestive digital platforms web links Saggestve dip platforms rb Mab: 11. htpss//swa 12, htips./erww.coursera.org/learn/physical-chemistry 13, bitps//www.mooc-list com/tags/physical-chemistry 14. httpsy//www.openisaming.com/courses/intraduction-to-physical-chemistry/ 15, buns:/www. my-mooe.com/en/eatezorie/chemistry 16. bttps:/ontinecourses, swayam2.ac.in/ncel? _sc1S/preview 17. hitps/swayam.gov.ind 18. https:i/www.coursera.org/browse/physical-sclence-and-cugineeriag/chemistry ‘This course can be opted us an elective by the students of following subjects: Chemistry in 12% Class ‘Suggested Continuous Evaluation Methods: Students can be evaluated on the basis of scare obtained ina mid-term exam, together with the petformance of other activities which can include short exams, in-class or on-line tests, home assignments, group discussions or oraf presentations, among others . Or Assesstnent and presentation of Assignment (10 marks) (04 Unit tests (Objective): Max marks of each unit test=10 | (10 marks) (Gverage of all 04 unit tests) ‘Overall performance throughout the semester ( Discipline, (05 marks) pacticipation in different activities) Course prevequlstes: To study this course, u student must have had the chemistry in class 12%, Physiesin 55 ‘Suggested equivalent online courses: Further Suggestions: 24Semester Il, Paper-2 (Practical): Course Title: Physical Analysis Programme: Diploma in Year: Two Semester: I Chemical Dynamics and Analytical Techniques Practical papor:2 Suihject: Chemistry Course Code. 8020302? —_ | Course Title: Physical Analysts ‘Canrse Outcomes: Upon snccessfal completion of this course students should be able 40 valibiale appavalus and prepare Solutions of various concentrations, estimation of components through vohumetric analysis; to perform dilatometric ‘experiments; one and two component phase equilibcium experiments. Credit Elective Max, Marks: 25 +25 Min, Passing Marks: Practical 60 h Unit Topics Noof Lectures 1 | Strengths of Sotution Calibration of fractional weights, pipettes and burettes. Preparation of standards solutions. 20 Dilution -0.1 M to 0.001 M solutions, Mole Concept and Conczntration Units :Mole Concept, molecular weight, formuls weight, and equivalent weight. Concentration units: Molasity, Formality, Normality, Molality, Mole fraction, Perceat by weight, Percent by Volume, Parts per thousand, Parts per millon, Parts per billion, pH, OH, milli equivalents, Milli oles IL | Surface Tension and Viscosity 06 1. Determination of surface tension af pure iguid or solution 2, Determination of viscosity of liquid pure iquid ar solution 1 | Boiling point and Transition Temperature 1. Boiling point of common organic liquid eompounds ANY FIVE Jnbutylalcohot| cyclohexanol, ethyl methyl ketone, cyclohexanone, acetylacetone, isobutyl methyl ketone) —!4 iscbutyl alcohol, acetonitrile, benzaldehyde and acetophenone, [Boiling points of the chosen) ‘organic compounds should preferably be within 180°C). 2. Transition Temperature, Determination of the transition temperature ofthe given substance by thermometric /dialometric method (e.g. MaCls 4H:0/S1Br2.2H20 ) Vv 2» 2s1. To study the effect ofa solute (e.g, NaCl, succinic acid) on the critical solution temperature of two partially miscible liquids (¢.g, phenotwater system) and to determine the concentration of that solute inthe given phenol-water system 2. To construct the phase diagram of two component (e.g. diphenylamine — benzophenone) system by cooling curve method. * Suggested Readings: 1. Skoog .D.A., West.D.M and Holler F.J,, “Analytical Chemistry: An Introduction’, 7th edition, Saunders coliege publishing, Phitadelphia,(2010). 2, Larry Hargis.G” Analytical Chemistry: Principles and Techniques” Pearson€(1988 ) Note: For the promotion of Mindi language, course books published in Hindi may be prescribed by the University Suggestive digital platforms web links 1. hitossfww Jabster.com/chemistry-virwalcabs! 2. huipsu/wrewvisb.convbrond-erea-chemical-siences 3. hutpil/chemed\ectiveorg/viabs ‘This course can be opted as an elective by the students of following subjects: Chemistry in 12" Cla Suggested Continuous Evaluation Methods: . Viva voce (10 marks) Mock test (18 macks) Overall performance (Osinarks) Course prerequisites: To study this course, 2 student must have Opted Sem-IIl, Theory Ppacr-1 Suggested equivalent online courses Further Suggestions: 6Semester IV Paper-1 (Theory) Course Title: Quantum Mechanics and Analytical Techniques Programme: Diploma in Year: Two. Somester: 1” ‘Chemicat Dynamics and ‘Analytical Techniques Popes Hlective Subject: Chemistry Course Code: BO20401T | Course Title: Quantum Mechanics and Analytical Techniques Course Outcomes:: Upon successful completion of this course students should be able to describe atomic structure} ‘elomentary quantum mechanicé ,wave fimction and its significance ;Schrodinger wave equation ond its applications Molecular orbital theory, basic ideas — Criteria for forming molecular orbital from atomic orbitals , Molecular Spectruscopy,| Rotational Spectrum ,vibrational Electronic Speetrum: photo chemistry and kinetics of photo chemical reaction Analytical chemistry plays an enormous role in our society, such as in drug misnufacturing, process control in industry, ceavironmental monitoring, medical diagnostics, food production, and forensic surveys, It is also of great importance in] diferent research areas. Anafytical chemistry is a science that is directed towards creating new knowledge so that chemical] analysis can be improved to respond to increasing or new demands, Students will be able to explore new areas of research in both chemistry and allied fields of science aad technoagy. Students will be able to function as a member ofan interdisciplinary problem solving team. - Students will be skilled in problem solving, critical thinking and analytical reasoning as applied to scientific problems ‘Students will goin en understanding of how to determine the structure of organic molecules using IR and NMR spectroscopic techniques + To develop basic skills required for purification, solvent extraction, TLC and columa chromatography Credits: 4 Elective ‘Max, Marks: 25475 Min, Passing Marks: Total No. of Lectures- = 60 Unit Topics No.of Lectures ¥ Atomic Structure: Idea of de-Broglic matter waves, Heisenberg uncertainty principle, atomic 5 orbitals, Schrbdinger wave equation, significance of ¥ and 2, quantum numbers, radial and angular ‘wave functions and probability distribution curves, shapes of, p, dy orbitals, Aufbau and Pauli exclusion principles, Hund's multiplicity rule, HE | Elementary Quantum Mechanics : Black-body radiation, Planck's radiation law, photoelectric effect) 10 heat capacity of solids, Bohy’s model of hydrogen atom (no derivation) and its defects, Compton effect, ‘desBeoglie hypottesis. Heisenberg uncertainty principle . Hamiltonian Operator. OC a‘Schrddinger wave equation (time dependent and time independeat) and its importance, physical interpretation of the wave function, postulates of quantim mechanics, particle in # one dimensional box. ‘Schtédinger wave equation for H-atom, separation Into three equations (without Uesivation), quantuny rocnbers and theit importance, Kytirogen like wave functions, radial wave functions, angular wave] functions. Molecula orbital theory, basic ideas Criteria for forming MO from AO, construction of MO) by LCAO Ha+ ton, onloulation of energy levels from wave functions, physical pictire of honing rn anti-bonding wave functions, concept of 6, 0°, x, x orbitals and theic characteristics. Molecular Spectroscopy: Introduction: Electromagnetic radiation, regions of the spectrum, basic} Seatyres of different spectrometers, statement of the Rom-Oppenheimer approximation, degrees of freedom ‘Rotational Spectrum:Diatomie molecules , Energy levels of a rigid rotor (semi-classical principles), selection rules, spectral intensity, distribution using population distribution (Maxwell Boltzmann distribution) determination of bond length, qualitative description of non-rigid rotor, isotope effect . Vibrational Spectrum: Infrared spectrum : Energy levels of simple harmonic oscillator, selection rules, pure vibrational spectrum, intensity, detcrminstion of force constant and qualiterive relation of for constant and bond energies, effect of anharmonic motion and isotope on the spectrum, idea of vibrational frequencies of diferent functional groups. Ramau spectrum: Concept of polarizability , pure rotational and pure vibrational, Raman spectra of diatomic molecules, selection rules. Electronic Spectrum: Concept of potential energy curves for bonding and antibonding molecular orbitals, quatitative description of selection rules. 10 Ww LV-Visible Spectroscopy : Origin of spectra, interaction of radiation with matter, fundamental laws of spectroscopy aad selection} rules, Types of electronic transitions, Amax, chromophores and auxochromes, Bathochromic andl Hypsoctuomie shifts, Intensity of absorption; application of Woodward Rules for calculation of kmax for he conjugated dienes: alicyclic, homoannular and heleroannular, extended conjugated systezs distinction benveen cis and trans isomers (Cis and trans stilbene) . Iatrared Spectroscopy: IR Spectroscopy: Fundamental end non-fundamental ssolecular vibrations; Hooke's law selection rule, AR absorption positions of various functional groups (C=O, OH, NH, COOH and nitrile) , Effect of H- bonding, conjugation, cesonznce aiid ring size of cyclic ketones and lactones on IR absoxptions; Fingerprint region and its significance; application in functional group analysis and and interpretation of LR. spectra of simple organie compounds. Identification cf the Carbonyl group in Ketones, Aldehydes, Carboxylic acids, Esters and Amides using IR Spectroscopy ow 28Vi) H-NMR Spectraseopy (PMR) NMR Spectroscopy: introduction; nuclear spin; NMR active molecules; basic principles of Protcn| Magnetic Resonance; chvive of solvent and internal standand; equivalent and non-oquivalent protons; chemical shift and factors influencing it; ring current effect; significance of the terms: up./downfield shielded and deshielded protons; spin coupling and coupling constant (Ist oide: speciza); relative intensities of Firs-order multiplets: Pascal's triangle; chemical and magnetic equivalence in NMR | anisotropic effects in alkene, alkyne, aldehydes and aromatics; NMI peak area, integration; relative peak] Positions with coupling patterns of common organic compounds; interpretation of NMR spectra vf simple eompounds. Applicattons of IR, UV andl NMR speuttuscopy for ientifieation of simple organi molecules such as Eshanol, Ethyl acetate, avefone, acetaldehyde, dimethylformanside, Cis and trans 1,2 imethy! eyeloprpanone, propene, vinyl chloride, acetophenone, benzaldchyde, phenol, Toluene and} ethyl benzene, 10 Vit | Introduction to Mass Spectrometry: Principle of inass spectrometry, the mass spectrum, mass) 3 spectrometry diagram, molecular ion, metastable ion, fragmentation process, MeLafferty rearrangement, ‘VIUL_| Separation Techniques: Solvent exteaction: Classification, principle and efficiency of the technique, Mechanism of extraction: extraction by solvation and chelation, Technique of extraction: batch] continuous and counter eurrent extractions. Qualitative and quantitative aspects of solvent extraction} extraction of metal ions from aqueous solution, extraction of arganic species from the aqueous and non aqueous medi, o Chromatography: Classification, principle and efficiency of the technique. Mechanism of separation adsorption, partition & ion exchange, Development of ehromatograms: frontal, elution and displacement methods, ‘Suggested Readings: 1 Albesty,R A, Physical Chemistry,4 th editionWiley Bastem Ltd 2008. 2. Atkins,P W,the elements of physical chemistry,Oxford ,1991 3. Barrow,G M,hnternetional student Edition MoGraw Hill, McGraw-Hill, 1973 4. Cotton,F.A, Wilkinson G and Gaus,P. 1, Basic Inongani¢ Chemistry 3" Eaition Wiley 1995 5. Lee,1.D, Concise Inorganic Chemistry 4 Edition ELBS,197 6.Clayden, I, Greeves, N., Warren, S., Organic Chemistry, Second edition, Oxford University Press 2012, 7. Silverstein, R. M., Bassler, G. C., Morell, TC. Spectrometric Identification of Organic Compounds, John Wiley ‘and Sons, INC, Fifth edition, 8. Pavia, D. L. etal. Introduction to Spectroscapy, Sth Ed, Cengage Learning India Ed, 9. Willard, HLH. eal: Instrumental Methods of Analysis, 1th Ed. Wardsworth Publishing Company, Belmont, California, USA, 1988, 10, Christian, G.D. Analytical Chemistry, 6th Ed. John Wiley & Sons, New York, 2004, 1. Harris, D.C. Exploring Chemical Analysis, Sth Ed. New York, WH. Freeman, 2016. 12. Khopkar, $.M, Basic Concepts of Analytical Chemistry. New Age International Publisher, 2008. 13. Mukerji, Singh,Kapoor, Organic Chemistry, Vol Land 2, Now Age Intemational 2014 4. RL Madan, CHEMSITRY FOR DEGREE STUDENTS ELECTIVE SEM V/VI AS PER CBS QUANTUM AND SPECTROSCOPY, S Chand Publis 15. ¥.R.Sharma, ELEMENTARY ORGANIC SPECTROSCOPY VOL 4, § Chand 16, GURDEEP RAJ, ADVANCED PHYSICAL CHEMSITRY, KRISHNA PUBLISHING V7. K L.Kapoor, A Textbook of Physical Chemistry - Quantum Chemistry and Molecular Spectroscopy 1Volume 4, Macmillan 18, TN SRIVASTVA AND PC KAMPOI, SYSTEMATIC NALYTICAL CHEMISTRY, SHOBAN ‘LAL NAGIN CHAND i) \ 29