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Long-Chain Polyunsaturated Fatty Acids (LCPUFAs) and the Developing Immune System: A Narrative Review

Nutrients 2021, 13, 247.

Endocannabinoids and Immunity

Cannabis and Cannabinoid Research Volume 1.1, 2016

Potential therapeutic applications of phytoconstituents as immunomodulators: Pre-clinical and clinical evidences

Phytotherapy Research. 2021;1–30.

Innate immune memory: towards a better understanding of host defense mechanisms

Current Opinion in Immunology 2014, 29:1–7

Trained Immunity: a Tool for Reducing Susceptibility to and the Severity of SARS-CoV-2 Infection

Cell 181, May 28, 2020

Trained Immunity: Reprogramming Innate Immunity in Health and Disease

Annu. Rev. Immunol. 2021. 39:667–93

Trained Immunity: a Tool for Reducing Susceptibility to and the Severity of SARS-CoV-2 Infection

Cell 181, May 28, 2020

Trained Immunity: a Tool for Reducing Susceptibility to and the Severity of SARS-CoV-2 Infection

Cell 181, May 28, 2020

Trained immunity as a novel therapeutic strategy

Current Opinion in Pharmacology 2018, 41

Natural Polysaccharides with Different Conformations: Extraction, Structure and Anti-tumor activity

J. Mater. Chem. B, 2020,

Training the trainable cells of the immune system and beyond

Nature Immunology
Trained immunity as a novel therapeutic strategy

Current Opinion in Pharmacology 2018, 41

Targeting Evolutionary Conserved Oxidative Stress and Immunometabolic Pathways for the Treatment of Respiratory Infectious Diseases

ANTIOXIDANTS & REDOX SIGNALING Volume 32, Number 13, 2020

Immunometabolic circuits in trained immunity

Seminars in Immunology 28 (2016) 425–430

Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis

Cell Metabolism 33, 411–423

 Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis

Figure 6. A Summary of the Observed Metabolic States of Quiescent, LPS Stimulated, and COPD Neutrophils A diagram showing the metabolic states of resting (A), stimulated (B), and
COPD (C) neutrophils showing increased glycolytic activity and glycogen synthesis in response to LPS and defective glycogen cycling and glycolysis in COPD. Genes identified to actively
regulate neutrophil glucose transport (Glut1), gluconeogenesis (GNG) (Fbp1 and Pck2), glycogenesis (Gys1, Gbe1, and Ugp2), and glycogenolysis (Pygl) are highlighted in red. Arrow
thickness indicates the relative flux through metabolic pathways with glycogenolysis and glucose oxidation highlighted in blue and glycogenesis and gluconeogenesis in green.

Cell Metabolism 33, 411–423

Altered Cellular Metabolism Drives Trained Immunity

Trends inEndocrinology & Metabolism, MonthYear,Vol.xx,No.yy

Targeting Evolutionary Conserved Oxidative Stress and Immunometabolic Pathways for the Treatment of Respiratory Infectious Diseases

ANTIOXIDANTS & REDOX SIGNALING Volume 32, Number 13, 2020

Reprogramming of mitochondrial metabolism by innate immunity

Current Opinion in Immunology 2019, 56:17–23

Amino Assets: How Amino Acids Support Immunity

Cell Metabolism 32, August 4, 2020

Amino Assets: How Amino Acids Support Immunity

Cell Metabolism 32, August 4, 2020

Amino Assets: How Amino Acids Support Immunity

Cell Metabolism 32, August 4, 2020

Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations

Front. Immunol. 9:2936.

Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations

Front. Immunol. 9:2936.

Immune Training Unlocks Innate Potential

Cell 172, January 11, 2018

The first line of defense: effector pathways of anti-fungal innate immunity

Current Opinion in Microbiology 2020, 58:160–165

Targeting Evolutionary Conserved Oxidative Stress and Immunometabolic Pathways for the Treatment of Respiratory Infectious Diseases

ANTIOXIDANTS & REDOX SIGNALING Volume 32, Number 13, 2020

Trained Immunity: Reprogramming Innate Immunity in Health and Disease

Annu. Rev. Immunol. 2021. 39:667–93

Trained immunity as a novel therapeutic strategy

Current Opinion in Pharmacology 2018,

𝜷-1,3/1,6-Glucans and Immunity: State of the Art and Future Directions

Mol. Nutr. Food Res. 2020, 1901071

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Henry Okigami

Henry Okigami
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