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Testicular Torsion
Authors

Michael A. Schick1; Britni T. Sternard2.

Affiliations
1 UC Davis Medical Center
2 Louisiana State University

Last Update: June 12, 2023.

Continuing Education Activity

Scrotal complaints are relatively common both in primary care and in the emergency department and comprise at least
0.5 percent of all emergency department visits. Testicular torsion is a true urologic emergency, and early identification
is critical to prevent the need for testicular amputation. Ultrasound is the ideal imaging modality to evaluate the
scrotal contents. This activity will review the most common causes of testicular torsion, the common presenting signs
and symptoms, and the treatment approach according to current evidence. This activity will highlight the role of the
interprofessional team in recognizing and treating testicular torsion.

Objectives:

Describe the epidemiology of testicular torsion.

Outline the presenting signs and symptoms of testicular torsion.

Summarize considerations that influence the management of testicular torsion.

Explain how the facilitation of interprofessional team education and discussion can optimize the effective
detection of testicular torsion and inform the need for subsequent evaluations.

Access free multiple choice questions on this topic.

Introduction
Scrotal complaints are relatively common in the emergency department, comprising at least 0.5% of all emergency
department visits. Testicular torsion is a time-dependent diagnosis, a true urologic emergency, and early evaluation
can assist in urologic intervention to prevent testicular loss. Ultrasound is the ideal imaging modality to evaluate the
scrotal contents. [1][2][3]

Testicular viability significantly decreases 6 hours after the onset of symptoms, hence early diagnosis is key.
Testicular torsion is most common in young people, but rarely may be seen in older individuals. Surgery is the only
treatment.

Etiology
The majority of cases occur in younger patients (< 25 years old) and are usually due to a congenital abnormality of the
processus vaginalis. The history of onset may be spontaneous, exertional, or, in fewer instances, associated with
trauma. Testicular torsion accounts for roughly one-quarter of scrotal complaints that present to the emergency
department. [4]

Testicular torsion is caused by twisting of the blood supply and spermatic cord. The tunica vaginalis is usually solidly
adhered to the posterolateral aspect of the testicle and within it, the spermatic cord is not mobile. If the attachment of
the tunica vaginalis is high, then this allows for the spermatic cord to twist inside, leading to intravaginal torsion. This
defect is referred to as the bell clapper deformity and is bilateral in at least 2/5th of cases.

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On the other hand, neonates tend to develop extravaginal torsion. This occurs because the tunica vaginalis has not
adhered to the gubernaculum and thus, both the tunica vaginalis and spermatic cord are prone to torsion. This
pathology can occur weeks or months prior to birth and is treated in a different manner. However, it is important to
know that neonates can also present with intravaginal torsion.

Testicular torsion has been known to occur in the presence of testicular malignancy in adults.

Epidemiology
The majority of cases occur in the adolescent age range (during periods of growth) but can occur at any age as well as
pre- or perinatal. Testicular torsion is the most significant cause of testicular loss.

Pathophysiology
As the testicle twists around the spermatic cord, venous blood flow is cut off, leading to venous congestion and
ischemia of the testicle. The testicle will become tender, swollen, and possibly erythematous. As the testicle further
twists, the arterial blood supply is cut off which leads to further testicular ischemia and eventually necrosis. [5]

In most individuals, the testicle rotates between 90-180 degrees and compromised blood flow. Complete torsion is
rare and quickly decreases the viability of the testes. Salvage is possible if the torsion is less than 8 hours but rare if
more than 24 hours have elapsed.

History and Physical

Testicular torsion often presents as an abrupt onset of unilateral scrotal pain. The pain may be constant or intermittent,
but not positional. The patient may have associated symptoms of nausea or vomiting. There may be associated lower
abdominal and inguinal pain, or alternatively, these may be the presenting complaint rather than scrotal pain.

The testicle may be in an abnormal or transverse lie and maybe in a high position. The testicle may be swollen,
erythematous, and have an absence of the normal cremasteric reflex; however, it should be noted that the presence or
absence of the cremasteric reflex is not as sensitive as once thought. Additionally, the cremasteric reflex is unreliable
in young patients, especially those less than one year old.

The Prehn sign is not reliable for predicting torsion (relief of pain with testicle elevation).

Torsion of the testicular appendages is more common and not dangerous. During early-onset, this may be
differentiated from testicular torsion by maximal tenderness to palpation near the head of the epididymis or testis, an
isolated tender nodule, and/or a blue dot appearance on the testis. The characteristic blue dot is due to the cyanotic
torsed appendage. The testicular appendage tends to calcify and degenerate over two weeks, and typically no surgical
intervention is required.

Other differential diagnoses to be considered are epididymitis, orchitis, inguinal hernia, symptomatic hydrocele,
testicular necrosis of other etiology, and scrotal hematoma.

Evaluation
The TWIST scoring system is often used to determine the presence of testicular torsion. It has been validated in
several studies in ruling out torsion. The TWIST tool includes:

Hard testis - 2

Swelling - 2

Nausea/vomiting - 1

Absent cremasteric reflex - 1

High riding testis - 1

The higher the score, the greater the probability that the patient has torsion. Ultrasound is recommended for those
with low scores. Those with high TWIST scores can be taken for surgery without ultrasound.

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Ultrasound is the primary diagnostic modality beyond the physical exam. Ultrasound for testicular torsion is
approximately 93% sensitive and 100% specific. Trained sonographers should perform this exam in a timely manner.
The point-of-care ultrasound technique to evaluate the testicle involves the high-frequency transducer (5 to 10 MHz),
ample ultrasound gel, and proper patient positioning. The process is described in brief below:

1. Place the patient supine and frog-legged with a towel under the scrotum for support. Using ample gel and
minimal pressure, evaluate the unaffected testicle first.

2. Scan the testicle in its entirety in both the transverse and longitudinal planes. Scan with grayscale first while
noting the presence of fluid collections and testicular texture. A normal testicular is around 4 x 3 x 2.5cm. In the
longitudinal plan or long axis, the testicle appears as an oval structure with homogenous echotexture and
smooth rounded borders. In the transverse plane or short axis, the testicle appears as a circular structure with
homogenous echotexture and smooth rounded borders. Side-by-side comparison of the testicles is critical to
evaluate for size, fluid collections, changes of echotexture, and discrepancies of color Doppler. If the testicle is
torsed, there will often be a hydrocele present with a testicle with reduced color or power flow.

Color flow doppler must be applied to both the affected and unaffected testicle of the patient. Begin with the
unaffected testicle to gain a sense of what normal vascular flow looks like in this particular patient. Power Doppler is
useful in the evaluation of testicular vascular flow as well. Power Doppler has greater sensitivity for vascular flow but
does not allow the examiner to discern between the arterial and venous flow.

Doppler can be employed to evaluate for both venous and arterial flow by placing the Doppler gate on areas of
vascular flow and evaluating for both venous and arterial Doppler waveforms. Arterial waveforms will have large
spikes due to the peaks of arterial blood pressure whereas venous waveforms appear typically as plateaus of Doppler
flow. Applying Doppler and checking for both venous and arterial flow can further demonstrate the severity of the
torsion. The same technique will be employed on the affected testicle.

Assessment for pyuria with urine analysis is typically part of the acute scrotal pain workup. The presence of pyuria is
consistent with epididymitis, orchitis, or urinary tract infection but does not rule out the possibility of testicular
torsion. [6][7]

Treatment / Management
Ultrasound is not a perfect test for testicular torsion, especially in the very young. For example, 40% of neonatal
testicles may have no apparent color flow doppler. If the clinical concern is high, seek urologic surgery consultation
immediately. Any delay in treatment could result in testicular necrosis and loss. The typical window of opportunity for
surgical intervention and testicular salvage is 6 hours from the onset of pain. Therefore, early urologic surgery
consultation upon presentation may be critical even in the absence of confirmatory testing.

Manual detorsion should be attempted if urological intervention is not immediately available. The abnormal testicle
should be rotated in a medial to lateral direction (open book) 180 degrees and then evaluated for pain relief. If the
pain is increased, consider rotating the testicle in the opposite direction. Ultrasound also can be used serially to
evaluate for return of blood flow at the bedside. If unsuccessful, further manual detorsion may be attempted as the
testicle can twist 180 degrees.[5][8][9]

In neonates, bilateral scrotal exploration is done. Contralateral orchiopexy is always done to prevent future torsion.
Patients who require an orchiectomy for a non-viable testis usually have a testicular prosthesis inserted. The
prosthesis is usually inserted 4-6 months after the initial surgery to allow for the inflammation to subside

Differential Diagnosis

Testis tumor

Epididymitis

Hydrocele

Traumatic hematoma

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Orchitis

Prognosis
Over the years there has been a marked improvement in the salvage of the testes following torsion However, poor
results still occur especially in African Americans, young patients, and those who lack health insurance. The best
results are obtained if the surgery is done within 8 hours of symptoms. However, recurrence can also occur after
orchiopexy.

Complications
Loss of testis

Infection

Infertility

Cosmetic deformity

Loss or diminished exocrine and endocrine function in men

Pearls and Other Issues

Ultrasound is a sensitive and specific test for the evaluation of testicular torsion. Early urology involvement is crucial
to avoid testicular loss. The use of color flow is essential in the evaluation of testicular torsion.

Enhancing Healthcare Team Outcomes

Testicular torsion is a surgical emergency that almost always presents to the emergency department. The disorder is
usually managed by an interprofessional team.

The first person to encounter the patient is the triage nurse who must be familiar with the symptoms of the disorder.
Time is of the essence and the nurse should be aware of torsion and quickly admit the patient and quickly notify the
ED physician. The ED physician should consult with a radiologist for the appropriate test and at the same time consult
with the urologist. The nurses should prepare the patient as if he will be going for surgery by keeping the child NPO
and having all the blood work completed.

IF the testing confirms torsion, the urologist is usually required to perform the surgery. The nurse should educate the
family and the patient about the potential complications, including loss of the testis and infertility. The nurse should
ensure that the patient is administered no food or drink by mouth and have the patient prepared to go for urgent
surgery. More importantly, the nurse should avoid giving any pain medications until the patient has been seen by the
urologist- or the pain medication will mask the symptoms and delay the diagnosis. Only through a systemic approach
to diagnosis and treatment, is the salvage of the testis a possibility.[10][11] Open communication between the team
members is vital is the outcomes are to be improved. [Level 5]

Outcomes

The outcomes of testicular torsion depend on when the patient presents to the ED and how quickly the diagnosis is
made and treatment is undertaken. Delays in diagnosis and treatment always lead to testicular atrophy. About 20-40%
of cases of testicular torsion result in an orchiectomy. The risk of losing a testis is much higher among
African Americans and younger males. For those who present within the first 6 hours of symptoms, the salvage rate is
nearly 100% but this number quickly drops to less than 50% if the delay in seeking help is more than 12-24 hours.
More importantly, when the testis is fixed by orchiopexy, there is also a potential for future torsion.[12][4] [Level 5]

Review Questions

Access free multiple choice questions on this topic.

Comment on this article.

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References
1. Monteilh C, Calixte R, Burjonrappa S. Controversies in the management of neonatal testicular torsion: A meta-
analysis. J Pediatr Surg. 2019 Apr;54(4):815-819. [PubMed: 30098810]
2. Osumah TS, Jimbo M, Granberg CF, Gargollo PC. Frontiers in pediatric testicular torsion: An integrated review of
prevailing trends and management outcomes. J Pediatr Urol. 2018 Oct;14(5):394-401. [PubMed: 30087037]
3. Velasquez J, Boniface MP, Mohseni M. StatPearls [Internet]. StatPearls Publishing; Treasure Island (FL): May 8,
2023. Acute Scrotum Pain. [PubMed: 29262236]
4. Naouar S, Braiek S, El Kamel R. Testicular torsion in undescended testis: A persistent challenge. Asian J Urol.
2017 Apr;4(2):111-115. [PMC free article: PMC5717970] [PubMed: 29264215]
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6. Mellick LB, Mowery ML, Al-Dhahir MA. StatPearls [Internet]. StatPearls Publishing; Treasure Island (FL): Apr
19, 2023. Cremasteric Reflex. [PubMed: 30020720]
7. Bandarkar AN, Blask AR. Testicular torsion with preserved flow: key sonographic features and value-added
approach to diagnosis. Pediatr Radiol. 2018 May;48(5):735-744. [PMC free article: PMC5895684] [PubMed:
29468365]
8. Friedman AA, Palmer LS, Maizels M, Bittman ME, Avarello JT. Pediatric acute scrotal pain: A guide to patient
assessment and triage. J Pediatr Urol. 2016 Apr;12(2):72-5. [PubMed: 27036070]
9. Fantasia J, Aidlen J, Lathrop W, Ellsworth P. Undescended Testes: A Clinical and Surgical Review. Urol Nurs.
2015 May-Jun;35(3):117-26. [PubMed: 26298946]
10. Tydeman C, Davenport K, Glancy D. Suspected testicular torsion - urological or general surgical emergency?
Ann R Coll Surg Engl. 2010 Nov;92(8):710-2. [PMC free article: PMC3229386] [PubMed: 21047450]
11. Murár E, Omaník P, Funáková M, Béder I, Horn F. [Acute scrotum is a condition requiring surgical
intervention]. Rozhl Chir. 2008 Oct;87(10):517-20. [PubMed: 19110944]
12. Howe AS, Vasudevan V, Kongnyuy M, Rychik K, Thomas LA, Matuskova M, Friedman SC, Gitlin JS, Reda EF,
Palmer LS. Degree of twisting and duration of symptoms are prognostic factors of testis salvage during episodes
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29354505]

Disclosure: Michael Schick declares no relevant financial relationships with ineligible companies.

Disclosure: Britni Sternard declares no relevant financial relationships with ineligible companies.

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Figures

Download video file.(242K, mp4)

Testicular Necrosis in the Setting of Testicular Torsion. Side-by-side comparison of testicles with power Doppler.
Contributed by Michael Schick DO, MA.

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