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  • Cholinergic Drugs

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    Ankit Pandey
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    Cholinergic drugs act on muscarinic and nicotinic acetylcholine receptors. Bethanechol and carbacol are Ach derivatives resistant to both true and pseudocholinesterase and have different effects. Methacholine is used in bronchial challenge tests to diagnose asthma as it acts quickly on bronchial my receptors. Peripheral effects of cholinergic drugs include increased contraction of muscles, the gastrointestinal tract, and bladder.

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    Cholinergic drugs act on muscarinic and nicotinic acetylcholine receptors. Bethanechol and carbacol are Ach derivatives resistant to both true and pseudocholinesterase and have different effects. Methacholine is used in bronchial challenge tests to diagnose asthma as it acts quickly on bronchial my receptors. Peripheral effects of cholinergic drugs include increased contraction of muscles, the gastrointestinal tract, and bladder.

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    3 views10 pages

    Cholinergic Drugs

    Uploaded by

    Ankit Pandey
    Cholinergic drugs act on muscarinic and nicotinic acetylcholine receptors. Bethanechol and carbacol are Ach derivatives resistant to both true and pseudocholinesterase and have different effects. Methacholine is used in bronchial challenge tests to diagnose asthma as it acts quickly on bronchial my receptors. Peripheral effects of cholinergic drugs include increased contraction of muscles, the gastrointestinal tract, and bladder.

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    of 10

    CHOLINERGIC

    DRUGS
    · Ach desivatives resistant to both true and Pseudocholine estace

    ① BETHANECHOL ② CARBACHOL
    ↳ ·
    M , / Mz > Mz M/Mg > Ma
    No nicotinic effect Max-Nicotinic effect
    -
    life (t1 /z)
    Longer half
    ·

    acholhasmax nicotinic setNoSystemizea


    closed Hancoma
    :
    Angle
    · Methacholine-used in bronchial challenge test
    ·
    ·
    bronchial
    Acts on My ReceptorsTo diagnose Asthma , as it is short
    Acting
    in the Bronchi

    · Peripheral effects of Cholinergic drugs are been in : -

    ↳ Muscl GIT Bladder

    · Bethan schol increases contraction of bladder and can be used


    in bladder
    atony.
    ↳ Also used in
    gastroparesis and postoperative paralytic ilsus

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