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AMMAN - JORDAN

‫المستوى الذهبي‬

‫جامعة كل الـعرب‬

Course Syllabus
Faculty of Pharmacy
Department of Pharmaceutical Chemistry and Pharmacognosy
Academic Year 2023 / 2024 Semester: Second

Course Title: Pharmaceutical Analytical Chemistry


Course No.: 905220
1501123
Prerequisite:
1501132
Concurrent: 905221
Credit hours: 2 credit hours
Department: Pharmaceutical Chemistry and Pharmacognosy
Coordinator: Dr. Samar Thiab
Educational Frame Level: 7
Mode of Instruction: On Campus
S1: Sun-Tue: 9-10
Lecture time: S2: Sun-Tue: 10-11
S3: Mon-Wed: 8-9
Lecture place: 10341

* Instructor:
Office Room
Lecturer Office Hours E-mail
Phone No.
Samar Thiab, PhD 1510 4216 As announced S_Thiab@asu.edu.jo

Course Description:
Analytical chemistry is a measurement science consisting of a set of powerful
ideas and methods that are able to get qualitative and quantitative information
about the matter. Qualitative analysis reveals the identity of the elements and
compounds in a sample, whereas quantitative analysis indicates the amount of
each substance in a sample.

Amman – Jordan :‫ _ عمان – األردن‬Fax: 5232899 :‫ _ فاكس‬Tel: 5609999:‫تلفون‬

UF 130 /2 :‫رمز النموذج‬ 24 / 233 ‫رقم القرار‬ 2021/10/25 ‫تاريخ االعتماد‬


AMMAN - JORDAN
‫المستوى الذهبي‬

‫جامعة كل الـعرب‬
Course Intended Learning Outcomes CILOS
Upon the completion of the course, this module should lead to the following learning
outcomes:

A. Knowledge and Understanding:


A1 Recall the background information of different chemical principles.
A2 Explain techniques that are useful in modern analytical methods.
A3 Apply the skills needed to solve quantitative analytical problems.

B. Cognitive and Intellectual Skills:


B1 Analyze problems in class.
B2 Demonstrate the role of analytical chemistry in pharmacy.

C. Subject Specific Skills:


C1 Interpret the sources of errors on analytical results.
C2 Differentiate between the different gravimetric methods.
C3 Analyze titration curves.

D. Transferable Skills (Competencies):


D1 Develop methods for tracing and measuring new substances including
medicinal drugs as active ingredients or in dosage forms.

Program Learning Outcomes (PLOs):

PLG1: Foundational Knowledge


- PLO Description
- PLO1: Learner - To Develop, integrate, and apply knowledge from the
foundational sciences (including pharmaceutical, social,
administrative, behavioral and clinical sciences): to
evaluate the scientific literature, explain drug action, solve
therapeutic problems, and advance population health and
patient centered care.

Course Learning Outcomes Alignment Matrix


CLO. 1 CLO. 2 CLO. 3 CLO. 4
(A1-A3) (B1-B2) (C1-C3) (D1)
Foundational Knowledge: PLO1 A1-A3 B1-B2 C1-C3 D1

Amman – Jordan :‫ _ عمان – األردن‬Fax: 5232899 :‫ _ فاكس‬Tel: 5609999:‫تلفون‬

UF 130 /2 :‫رمز النموذج‬ 24 / 233 ‫رقم القرار‬ 2021/10/25 ‫تاريخ االعتماد‬


AMMAN - JORDAN
‫المستوى الذهبي‬

‫جامعة كل الـعرب‬
Course Contents and Schedule
Teaching Evaluation
Week Date Topics to be covered & learning tools CLOs PLOs
methods
The Nature of Analytical
Chemistry In-class
1 3/3/2024 A1 1
Introduction: The Role of lectures
Analytical Chemistry
Data Handling in Analytical
Chemistry
• Accuracy and Precision In-class
2 10/3/2024 Homework A1, B2, C1 1
• Errors in Chemical Analysis lectures
• Significant Figures
❖ Absolute and relative uncertainty
❖ Calculations Used in Analytical
Chemistry
• SI Units
In-class
3 17/3/2024 • Conversion Between Units A3, B1 1
lectures
• Concentration of Solutions
• The Equilibrium Constant
Le Châtelier’s principle
Classical Methods of Analysis
❖Gravimetric Methods of
Analysis In-class A1, A2, A3,
4 24/3/2024 Quiz 1
• Precipitation Gravimetry lectures B1, B2, C2
•Calculation of Results from
Gravimetric Data
❖Gravimetric Methods of
Analysis In-class A1, A2, A3,
5 31/3/2024 1
• Applications of Gravimetric lectures B1, B2, C2
Methods
6 7/4/2024 Eid Holidays
❖Titrations in Analytical
Chemistry
• Some Terms Used in Volumetric In-class A1, A2, A3,
7 14/4/2024 1
Titrations lectures B1, B2, C3
• Standard Solutions
• Volumetric Calculations
❖Titrations in Analytical
Chemistry In-class A1, A2, A3,
8 21/4/2024 1
• Gravimetric Titrations lectures B1, B2, C3
• Titration Curves
❖Principles of Neutralization
Titrations In-class Midterm A1, A2, A3,
9 28/4/2024 1
•Introducing Acids and Bases lectures Exams B1, B2, C3
• Solutions and Indicators for

Amman – Jordan :‫ _ عمان – األردن‬Fax: 5232899 :‫ _ فاكس‬Tel: 5609999:‫تلفون‬

UF 130 /2 :‫رمز النموذج‬ 24 / 233 ‫رقم القرار‬ 2021/10/25 ‫تاريخ االعتماد‬


AMMAN - JORDAN
‫المستوى الذهبي‬

‫جامعة كل الـعرب‬
Acid/Base Titrations
• Titration of Strong Acids and
Bases
❖Principles of Neutralization
Titrations
• Titration Curves for Weak Acids In-class A1, A2, A3,
10 5/5/2024 1
• Titration Curves for Weak Bases lectures B1, B2, C3
• The Composition of Solutions
During Acid/Base titrations
❖Complex Acid/Base Systems
• Mixtures of Strong and Weak
Acids or Strong and Weak Bases In-class A1, A2, A3,
11 12/5/2024 1
• Polyfunctional Acids and Bases lectures B1, B2, C3
•Buffer Solutions Involving
Polyprotic Acids
❖Complexation and Precipitation
Reactions
• The Formation of Complexes In-class A1, A2, A3,
12 19/5/2024 1
•Titrations with Inorganic lectures B1, B2, C3
Complexing Agents
• Organic Complexing Agents
❖Oxidation/Reduction Titrations A1, A2, A3,
In-class
13 26/5/2024 • Theory of Redox Titrations B1, B2, C3, 1
lectures
• Redox Indicators D1
14 4/6/2022 Final Exams

Grading Plan and Assessment Tools


Course Evaluation Plan
Assessment Tools Degree Class Outputs
Midterm exam 30 A1, A2, A3 B1, B2 C1, C3
Final exam 50 A1, A2, A3 B1, B2 C1, C2, C3
Assignments 20
Evaluation Jobs and Duties
Case Studies
Discussion and Interaction
Group Activities
Lab Quizzes
Presentations
Quizzes 5 A1, A3 B1, B2 C1
Reports
Projects 15 A1, A2, A3 B1, B2 C2
Others
Total 20

Amman – Jordan :‫ _ عمان – األردن‬Fax: 5232899 :‫ _ فاكس‬Tel: 5609999:‫تلفون‬

UF 130 /2 :‫رمز النموذج‬ 24 / 233 ‫رقم القرار‬ 2021/10/25 ‫تاريخ االعتماد‬


AMMAN - JORDAN
‫المستوى الذهبي‬

‫جامعة كل الـعرب‬
Supplementary Reading
Textbook:
1. Fundamentals of analytical chemistry, 9th Edition, by Wenzel TJ. Douglas
A. Skoog, Donald M. West, F. James Holler, and Stanley R. Crouch.
2. Exploring Chemical Analysis 5th Edition, by Daniel C. Harris.

References:
1. Analytical Chemistry, 7th Edition, by Gary D. Christian, Purnendu K.
Dasgupta, Kevin A. Schug.
2. Analytical chemistry 2.1 by David Harvey.
Recommended for reading:
1. Analytical Chemistry I, by Ritgen Ulf Ritgen, 2023.
Electronic material:
1. https://www.youtube.com/watch?v=K7VM-8tiEsM
2. https://www.youtube.com/watch?v=8Cl5CeiT7hU
3. https://www.youtube.com/watch?v=uuanyWZvDHw

Other sites:
1. https://www.sciencedirect.com/handbook/comprehensive-analytical-chemistry

Subject Coordinator: Dr. Samar Signature: Dr. Samar Thiab


Head of Curriculum Committee Dr. Reem Abutayeh Signature: -------------------------
Department Head Dr. Reem Abutayeh Signature: -------------------------
Faculty Dean Dr. Samar Thiab Signature: -------------------------

Last update date: February 2024.

Copy to:
- Department Head.
- Head of Curriculum Committee.
- Course File.

Amman – Jordan :‫ _ عمان – األردن‬Fax: 5232899 :‫ _ فاكس‬Tel: 5609999:‫تلفون‬

UF 130 /2 :‫رمز النموذج‬ 24 / 233 ‫رقم القرار‬ 2021/10/25 ‫تاريخ االعتماد‬

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