Professional Documents
Culture Documents
Intensive Care Unit Models Do You Want Them To Be.11
Intensive Care Unit Models Do You Want Them To Be.11
Intensive Care Unit Models Do You Want Them To Be.11
A critical review
Debashish Chowdhury, Ashish K Duggal
nYQp/IlQrHD3i3D0OdRyi7TvSFl4Cf3VC1y0abggQZXdtwnfKZBYtws= on 03/18/2024
Website:
www.neurologyindia.com
DOI: Abstract:
10.4103/0028-3886.198205
Intensive care is a specialized branch of medicine dealing with the diagnosis, management, and follow up of
PMID: critically ill or critically injured patients. It requires input from other branches of medicine on various issues.
xxxx A critical care specialist has expertise in managing such patients round the clock. Based on his freedom to
take decisions in the intensive care unit (ICU), different types of ICUs – open, closed, or semi‑closed – have
been defined. There is no doubt that all critical patients should be evaluated by an intensivist. Therefore, it is
argued that a closed ICU model would be the ideal model. However, this may not always be feasible and other
models may be more useful in resource‑limited countries. In this review, we compare the different formats of
ICU functioning and their suitability in different hospitals.
Key Words:
Closed ICU, hospital stay, intensive care unit, mortality, open ICU, semi‑closed ICU
Key Messages:
• Neurocritical care is a highly-specialized field but there is a paucity of neurocritical care specialists
• A closed ICU mode headed by an intensivist may be ideal but not cost – effective especially in a country
like India
• A semi-closed ICU with appropriate well-written protocols and a good nurse-patient ratio could be the
solution to the reduction in mortality rates and the reduction in the duration of hospital stay so that the
ICUs are utilized in a cost – effective manner.
© 2017 Neurology India, Neurological Society of India | Published by Wolters Kluwer - Medknow 39
Chowdhury and Duggal: Open or closed ICU models
ventilating them with an oxygen/nitrogen mixer using positive for ICU admission and discharge. Although the primary
pressure, which resulted in a reduction in mortality from polio physician may have less expertise in critical care medicine,
from 80% to 25%.[5] Ibsen went on to open the first ICU in 1953, it is argued that his long relationship with the patient may
which was replicated around the world, and the branch of provide improved patient care and a greater satisfaction.
critical care medicine was established. In 1958, Dr Max Harry However, the downside is greater variability in practice
Weil and Dr Hebert Shubin opened a 4‑bedded shock ward patterns. Single‑organ specialists may not be aware of the
in Los Angeles County – University of Southern California overall management plan, resulting in potentially unnecessary
Downloaded from http://journals.lww.com/neur by BhDMf5ePHKav1zEoum1tQfN4a+kJLhEZgbsIHo4XMi0hCywCX1AW
Medical Center, Los Angeles, USA, to improve the recognition or conflicting orders and increased expenses.
and treatment of serious complications in critically ill patients.[6]
Closed intensive care unit model
Indian scenario In a closed model ICU, all patients admitted to the ICU are
The first ICU in India was actually a coronary care unit, started cared for by an intensivist‑led team that is responsible for
nYQp/IlQrHD3i3D0OdRyi7TvSFl4Cf3VC1y0abggQZXdtwnfKZBYtws= on 03/18/2024
in 1968 at the King Edward VII Memorial Hospital, Mumbai, making clinical decisions.[11] The admissions and discharges
followed by another one at the Breach Candy Hospital.[7] Since are controlled by an on‑site ICU physician in most closed ICU
then, intensive care has grown into a specialty in its own right. models. Because most ICU patients have similar problems,
regardless of the reason for their critical illness, it is believed
Rapid growth that management by a team of specially qualified intensive care
Today, the ICUs comprise up to 10% of all hospital beds and physicians and nurses provides patients with better care and
consume as much as 25–30% of hospital resources.[8] In India, is associated with improved outcomes with a more efficient
critical care beds account for 5–8% of the total bed strength in use of ICU resources.
large public teaching hospitals.[7]
Intensivist co‑management
Changes in Organizational Structure of Intensive This involves an open ICU model in which all patients receive
Care Units mandatory consultation from an intensivist.[11] The internist,
family physician, or surgeon remains a co‑attending‑of‑record
There has been a debate on the role of “intensivists” in the with the intensivists collaborating in the management of all
management of critically ill patients and their impact on patient ICU patients.
outcomes. Many of the initial critical care units were staffed
by physicians whose primary specialties were anesthesiology Hybrid or transitional intensive care unit or semi‑closed
or internal medicine.[6] Over the past few years, critical care intensive care unit model
medicine has become a full subspecialty and can no longer Hybrid/transitional/semi‑closed ICU is one in which critical
be regarded just as a part of anaesthesia, medicine, surgery, care team provides direct patient care in collaboration with
or any other speciality. The understanding of physiology in other ‘privileged’ physicians, who are also allowed to write
critically ill patients and evidence‑based practice is essential in orders.[12] In this model, the primary treating physicians are
the management of ICU patients. In the ICU, the 9 physiological not a part of the ICU team, but remain actively involved in
systems that are monitored include the cardiovascular, central their patients’ care. Many surgical and cardiothoracic ICUs
nervous, endocrine, gastrointestinal/nutrition, hematology, maintain this model.
microbiology/sepsis, periphery/skin, renal/metabolic, and
respiratory systems. An intensivist is usually a physican trained Multiple consultant model
to do this and has undergone primary training in medicine, Multiple consultant model is one where multiple specialists are
surgery, anesthesiology, or pediatrics followed by 2–3 years involved in the patient’s care (a pulmonologist or intensivist
of critical care medicine training.[9] In India, according to might be consulted for ventilator management, but no one is
the Indian Society of Critical Care Medicine (ISCCM),[10] an designated specifically as the consultant intensivist). In some
intensivist should have a postgraduate qualification in internal cases, the intensivist may act as the team leader and coordinate
medicine, anesthesia, pulmonary medicine, or surgery and between all consultants, providing an integrated approach to
either an additional qualification in intensive care, or at least the patient and family.[13]
an year training in a reputed ICU abroad.
Mixed intensive care unit models
Types of Intensive Care Unit Models In practice, the above mentioned models overlap to a
considerable extent. The level of involvement of the intensivist
Based on the extent of involvement and supervision by critical may vary from daily rounds by an intensivist to the presence
care physicians, ICUs function on 6 different models. of a full‑time intensivist in the ICU. Table 1 highlights the
advantages and disadvantages of various ICU models. Because
Open intensive care unit model this article primarily caters to neurosurgeons and neurologists,
This is an ICU in which patients are admitted under the care of a brief mention may be made regarding the neuro‑ICUs.
an internist, family physician, surgeon, or any other primary
attending physician, with the intensivists being available to The neurosciences intensive care unit
provide their expertise via elective consultation.[9] Intensivists Historically, the first neurosciences intensive care unit (NICU)
may play a de facto primary role in the management of some was opened in John Hopkins Hospital in 1932 by Dandy.
patients, but only within the discretion of the admitting NICUs may admit both neurological and neurosurgical
physician, and have no overreaching authority over patient patients, but some have remained largely neurosurgical or
care. The patient’s primary physician determines the need have specifically catered to neuro‑trauma patients. The most
common diagnosis at admisson include are stroke, head injury, detailed in Table 2. All this requires a good knowledge of the
brain tumor, post‑hypoxic encephalopathy, neuromuscular interface between the brain and other organ systems in the
respiratory failure, status epilepticus, various neurological face of a critical illness. However, neurointensitivists are an
infections, and admission for immediate postoperative extremely rare breed, and currently in USA, there are only 45
observation. NICUs can also be open, closed, or semi‑closed, centres that have one. In India, to the best of our knowledge,
as discussed previously. The increasing use of intravenous there is no dedicated fellowships in neurocritical care, although
thrombolysis and endovascular interventions for stroke implies there are post‑ doctoral courses offered in neuroanesthesia.
Downloaded from http://journals.lww.com/neur by BhDMf5ePHKav1zEoum1tQfN4a+kJLhEZgbsIHo4XMi0hCywCX1AW
that more and more stroke patients are being treated in the
NICU. The advent of closed NICUs required the arrival of
another new subspecialist – the neurointensitivist – who was
Evidence in the Medical Literature: Should Intensive
required to assume a primary care role for patients in the ICU, Care Units always Function on a Closed Basis?
coordinating both neurological and medical management.
nYQp/IlQrHD3i3D0OdRyi7TvSFl4Cf3VC1y0abggQZXdtwnfKZBYtws= on 03/18/2024
Further, in NICUs, certain highly specialized monitoring may Several studies have attempted to identify the consequences of
be required [Table 2]. The neurointensitivist should not only these different ICU staffing patterns on patient care.[14‑20] These
be well‑versed in the standard ICU protocols, but also in the are summarized in Table 3. A critical analysis of these studies
specialized neuro‑critical monitoring and interventions, as is presented below.
Table 3: Summary of the studies comparing open and closed ICU formats
Authors Study setting Study year ICU type Controls Intensivist Outcome
intervention
Reynolds et al.[14] Tertiary 1982-1984 Medical Historical Closed Mortality Relative Risk Reduction
care, urban, 23%
teaching
hospital
Multz et al.[15] Teaching 1992-1993 Medical Historical and Closed Mortality Relative Risk Reduction
hospitals concurrent Retrospective: 19%
Prospective: 26%
Carson et al.[16] Teaching 1995-1996 Surgical Historical Closed Mortality Relative Risk Reduction:
hospital 58%
Hanson et al.[17] Teaching 1999 Surgical Concurrent Closed vs open Reduced length of stay in ICU
hospital and fewer complications in closed
model
Pollack et al.[18] Teaching 1989-1992 Paediatrics Historical Closed vs open Mortality Relative Risk Reduction
hospital by 25%
Dimick et al.[19] Multiple ICUs: 1994-1998 Surgical Cross sectional Mixed ICUs In‑hospital mortality rate was
Patients 1.5% in closed model versus
with hepatic 7.8% in open ICUs
resection
Manthous et al.[20] Community 1992-1994 Medical Historical Open vs closed Mortality reduction by 29% after
teaching conversion to closed model
hospital
Pronovost Systematic 2002 All types Historical and Low‑intensity Pooled estimate across all
et al.[21] review concurrent (open) vs or high studies=61%
intensity (closed)
Levy et al.[24] 100 ICUs in 2008 All types Cross‑sectional ‑ Standardized mortality ratio in
USA closed ICU was 1.09 vs 0.91 in
open ICUs
Kim et al.[25] 169 ICUs in 2010 All types Concurrent ‑ Lower odds of death were in
Pennsylvania closed ICU (OR 0.78) vs OR of
0.88 in open ICUs
van der Sluis Netherlands 1996-1998 General Historical Open vs closed Significant decrease in
et al.[26] (open format) and trauma mortality (25.7% vs 15.8%,
and 2003-2005 surgery P-value=0.001) and hospital
(closed format) stay (21 vs 17 days,
P-value=0.03)
Sakr et al.[27] 2015 All types Observational-1 day Open (82.9%) vs Availability
point prevalence closed (17.1%) of an in‑house intensivist 24 h/d
study in May 2007 was associated with
a trend toward a reduced risk of
in‑hospital death but ICU format
did not influence the adjusted risk
of in‑hospital death
In a systemic review Pronovost et al., concluded that 2011–2012 academic year, 1957 trainees were enrolled in the
high‑intensity staffing (mandatory intensivist consultation or a adult critical care medicine fellowships (surgery, anesthesia,
closed ICU) was associated with a lower ICU mortality rate in medical critical care, and pulmonary/critical care), which is
93% of studies with a reduced length of stay in the ICU.[21] It is grossly inadequate.[29] The situation is worse in India with
generally agreed that intensivists can better manage critically ill a much larger population when compared to USA with a
patients because of a better understanding and management of total of 13 DM critical care and 17 FNB critical care seats
ICU pathology, better use of evidence‑based medicine, increased annually.[30] It is impossible to provide a comprehensive critical
Downloaded from http://journals.lww.com/neur by BhDMf5ePHKav1zEoum1tQfN4a+kJLhEZgbsIHo4XMi0hCywCX1AW
usage of protocols, and better ventilation management. As a care management in our country with such a small number of
result, various bodies have recommended that all patients in critical care specialists, and thus it is impossible to follow the
adult or pediatric general medical and/or surgical ICUs and closed model in most of the places, although the Indian Society
NICUs should be managed or co‑managed by an intensivist. of Critical Care Medicine (ISCCM) discourages adoption or
[22]
There are, however, some problems with the definitiveness continuance of open ICUs.[1]
nYQp/IlQrHD3i3D0OdRyi7TvSFl4Cf3VC1y0abggQZXdtwnfKZBYtws= on 03/18/2024
between the intensivist supply and demand, this concept specific extubation criteria for the neurological patient has proven
appears too ambitious, However, a new development has to be problematic. The patients’ respiratory muscle strength
occurred, at least in the West. Here the growing intensivist and their ability to maintain oxygenation with decreasing
shortage has coincided with the appearance of hospitalists,[35] ventilatory support have received maximum attention.[40,41] The
(physicians who focus on the care of hospitalized medical most consistent airway parameters associated with extubation
patients) on the healthcare landscape. Eighty‑five percent of success were the presence of a spontaneous cough and a required
practicing hospitalists are internists, who have historically suctioning frequency of >2 hours.[42] For extubation, it is reasonable
Downloaded from http://journals.lww.com/neur by BhDMf5ePHKav1zEoum1tQfN4a+kJLhEZgbsIHo4XMi0hCywCX1AW
been well trained to manage acutely ill hospitalized patients. to incorporate the same pulmonary function tests that are used
With their consistent presence in the hospital (many programs during intubation.
provide 24 × 7 in‑house coverage), hospitalists see patients
several times a day, if necessary, and can respond to their Thus, a protocol driven semi‑closed ICU may be a solution for
acute needs in real time. Enhancing hospitalists’ skills to resource‑limited countries like India.
nYQp/IlQrHD3i3D0OdRyi7TvSFl4Cf3VC1y0abggQZXdtwnfKZBYtws= on 03/18/2024
9. Rothschild J. Closed intensive care units and other models of care for 26. van der Sluis FJ, Slagt C, Liebman B, Beute J, Mulder JW, Engel AF.
critically ill patients. In: Shojania KG, Duncan BW, McDonald KM, The impact of open versus closed format ICU admission practices
et al., editors. Making Health Care Safer: A Critical Analysis of on the outcome of high risk surgical patients: A cohort analysis.
Patient Safety Practices. Evidence Report/Technology Assessment BMC Surg 2011;23:11‑8.
No. 43. Rockville, MD: Agency for Healthcare Research and 27. Sakr Y, Moreira CL, Rhodes A, Ferguson ND, Kleinpell R,
Quality; 2001. p. 413‑22. Pickkers P, et al. The impact of hospital and ICU organizational
10. Divatia JV, Baronia AK, Bhagwati A, Chawla R, Iyer S, Jani CK, factors on outcome in critically ill patients: Results from the
et al. Critical care delivery in intensive care units in India: Defining Extended Prevalence of Infection in Intensive Care study. Crit Care
Downloaded from http://journals.lww.com/neur by BhDMf5ePHKav1zEoum1tQfN4a+kJLhEZgbsIHo4XMi0hCywCX1AW
et al. Transition to a semiclosed surgical intensive care unit (SICU) 29. List of ACGME Accredited Programs and Sponsoring Institutions.
leads to improved resident job satisfaction: A prospective, Available from: http://www.acgme.org/adspublic. [Last accessed
longitudinal analysis. J Surg Educ 2009;66:25‑30. on 2015 Aug 10].
13. Brilli RJ. Critical care delivery in the intensive care 30. Ananthakrishnan N. Distribution of postgraduate medical seats in
unit: Defining clinical roles and the best practice model. different disciplines: Is there rationality in decision‑making? Natl
Crit Care Med 2001;29:2007‑19. Med J India 2011;24:365‑7.
14. Reynolds NH, Haupt MT, Thill‑Baharozian MC, Carlson RW. Impact 31. Embriaco N, Papazian L, Kentish‑Barnes N, Pochard F, Azoulay E.
of critical care physician staffing with septic shock in a university Burnout syndrome among critical care healthcare workers. Curr
hospital medical intensive care unit. JAMA 1988;260:3446‑50. Opin Crit Care 2007;13:482‑8.
15. Multz AS, Chalfin DB, Samson IM, Dantzker DR, Fein AM, 32. Maslach C, Schaufeli WB, Leiter MP. Job burnout. Annu Rev
Steinberg HN, et al. A closed medical intensive care unit (MICU) Psychol 2001;52:397‑422.
improves resource utilization when compared with an open MICU. 33. Maslach C, Jackson S, Leiter MP. Maslach Burnout Inventory
Am J Respir Crit Care Med 1998;157:1468‑73. Manual. 3rd ed. Consulting Psychologists. Palo Alto, CA: Press Inc.;
16. Carson SS, Stocking C, Podsadecki T, Christenson J, Pohlman A, 1996.
MacRae S, et al. Effects of organizational change in the medical 34. Hillman K. Critical care without walls. Curr Opin Crit Care
intensive care unit of a teaching hospital: A comparison of “open” 2002;8:594‑9.
and “closed” formats. JAMA 1996;276:322‑8. 35. Siegel EM, Dressler DD, Dichter JR, Gorman MJ, Lipsett PA.
17. Hanson CW, Deutschman CS, Anderson HL, Reilly PM, Behringer. Training a hspital list workforce to address the intensivist shortage
EC, Schwab CW, et al. Effects of an organized critical care service in American hospitals: A position paper from the Society of Hospital
on outcomes and resource utilization: A cohort study. Crit Care Med Medicine and the Society of Critical Care Medicine. J Hosp
1999;27:270‑4. Med 2012;7:359‑64.
18. Pollack MM, Katz RW, Ruttimann UE, Getson PR. Improving 36. Brook AD, Ahrens TS, Schaiff R, Prentice D, Sherman G,
the outcome and efficiency of intensive care: The impact of an Shannon W, et al. Effect of a nursing‑implemented sedation
intensivist. Crit Care Med 1988;16:11‑7. protocol on the duration of mechanical ventilation. Crit Care Med
19. Dimick JB, Pronovost PJ, Heitmiller RF, Lipsett PA. Intensive care 1999;27:2609‑15.
unit physician staffing is associated with decreased length of stay, 37. Leape LL, Cullen DJ, Clapp MD, Burdick E, Demonaco HJ,
hospital cost, and complications after esophageal resection. Crit Erickson JI, et al. Pharmacist participation on physician rounds and
Care Med 2001;29:753‑8. adverse drug effects in the intensive care unit. JAMA 1999;281:267-70.
20. Manthous CA, Amoateng‑Adjepong Y, al‑Kharrat T, Jacob B, 38. Taniguchi T, Okajima M. Effect of organizational structure of the
Alnuaimat HM, Chatila W, et al. Effects of a medical intensivist ICU on the prognosis: Open format versus semi‑closed format. Crit
on patient care in a community teaching hospital. Mayo Clin Proc Care 2013;17(Suppl 2):517.
1997;72:391‑9. 39. MacIntyre NR. Evidenced based guidelines for weaning and
21. Pronovost PJ, Young T, Dorman T, Robinson K, Agnus DC. discontinuing ventilatory support: A collected task force facilitatedby
Association between ICU physician staffing and outcomes: the American College of Chest Physicians; the American Association
A systematic review. Crit Care Med 1999;27:A43. of Respiratory Care; and the American College of Critical Care
22. The Leapfrog Group Factsheet. ICU Physician Staffing (IPS). Medicine. Chest 2001;120(6 suppl):S375-95.
Available from: http://www.leapfroggroup.org/media/file/ 40. Esteban A, Alía I, Tobin MJ, Gil A, Gordo F, Vallverdú I, et al. Effect
FactSheet_IPS.pdf. [Last accessed on 2015 Aug 10]. of spontaneous breathing trial duration on outcome of attempts
23. Pronovost P J , Angus DC, Dorman T, Robin s o n K A , to discontinue mechanical ventilation: The Spanish lung failure
Dremsizov TT, Young TL. Physician staffing patterns and clinical collaborative group. Am J Respir Crit Care Med 1999;159:512‑8.
outcomes in critically ill patients: A systematic review. JAMA 41. Vallverdu I, Calaf N, Subirana M, Net A, Benito S, Mancebo J.
2002;288:2151‑62. Clinical characteristics, respiratory functional parameters,
24. Levy MM, Rapoport J, Lemeshow S, Chalfin DB, Phillips G, and outcome of a two hour T‑ piece trial in patients weaning
Danis M. Association between Critical Care Physician management from mechanical ventilation. Am J Respir Crit Care Med
and patient mortality in the Intensive Care Unit. Ann Intern Med 1998;158:1855‑62.
2008;148:801‑9. 42. Coplin WM, Pierson DJ, Cooley KD, Newell DW, Rubenfeld GD.
25. Kim MM, Barnato AE, Angus DC, Fleisher LA, Kahn JM. The effect Implications of extubation delay in brain injured patients
of multidisciplinary care teams on intensive care unit mortality. Arch meeting standard weaning criteria. Am J Respir Crit Care Med
Intern Med 2010;170:369‑76. 2000;161:1530‑6.