DRUG STUDY

Drug Name / Dosage / Route / Classification / Mechanism Indication / Side Effects Adverse Reactions Nursing considerations
Frequency of Action contraindication
GENERIC NAME: PHARMACOTHERAPEUTIC INDICATIONS: FREQUENT: BEFORE / BASELINE
Zinc Oxide + Benzoic Acid + CLASSFICATION: - Superficial fungal - Warm - Severe skin ASSESSMENT:
Sulfur + Salicylic Acid
Imidazole derivatives infection (tinea pedis, sensation irritation • Assess the patient for
tinea corporis, tinea allergy to the ingredients of
BRAND NAME:
CLINICAL CLASSIFICATION: cruris, tinea OCCASIONAL: - Redness the product
Dr. S. Wong's Bioderm
Antifungal / Antibacterial versicolor, and - dryness, and • Check the area if
USUAL DOSAGE/ FREQUENCY: candidiasis) peeling of the - Irritation damaged skin integrity is
MECHANISM OF ACTION: - Adults and children skin present
1 to 3 times a day to the affected
area age 2 and older - Pruritus DURING:
THERAPEUTIC EFFFECT: - eczema, blackheads, - Abnormal • Wash the affected area
USUAL ROUTE: killing the fungus or yeast pimples, hair texture - Scalp pustules with soap and warm water
Topical (fungicidal) or preventing its furunculosis, acne, • Dry the skin gently but
growth (fungistatic) skin itch, white spots - Increase in - Stinging with thoroughly
DRUG ORDER: (ap-ap), hand itch, normal hair cream • Apply the ointment
--- PHARMACOKINETICS: boils, barber’s itch, loss AFTER/EVALUATION:
Absorption: not absorbed insect bites, and • Check for any side
systemically after topical other skin irritations - Oiliness or effect of the drug such as
administration on the head and on dryness of redness
Distribution: varies the body. hair and scalp • Ask the client if pain in
according to the tissue - Effective for prickly the area is present
sampled, the underlying heat, dhobie itch,
disease and the dose and mange. PATIENT HEALTH TEACHING:
duration of treatment - Hongkong foot and • Tell patient to stop drug
• 83.7% plasma protein itching dandruff and notify prescriber if
(mainly albumin) bound, and hypersensitivity reaction
15.3% is erythrocyte bound, CONTRAINDICATIONS: occurs
for a total of 99% binding
 within the plasma, resulting
in only 1% of free drug
Metabolism: ---
CAUTIONS:
Excretion: mainly excreted in
the feces
Half life: unknown
PHARMACODYNAMICS:
• Interferes with the
fungal cell-wall synthesis by
increasing cell-wall
permeability that makes the
fungus susceptible to
osmotic instability.
DRUG-DRUG INTERACTION:
None known.
Reference: Daneshmend, T. K., & Warnock, D. W. (1988). Clinical pharmacokinetics of ketoconazole. Clinical pharmacokinetics, 14(1), 13–34.
https://doi.org/10.2165/00003088-198814010-00002
- Hypersensitivity to • Advice patient to check
ingredients. with prescriber if condition
worsens; drug may have to be
stopped and diagnosis
reevaluated.
- Pregnant and • Warn patient to avoid
breastfeeding – drug contact with eyes.
category C for • Tell patient to continue
salicylic acid drug for intended duration of
- Avoid contact with therapy, even if signs and
eyes and mucous symptoms improve soon after
membrane starting treatment.
- Do not apply on • Tell patient not to store
sunburned area, drug above room temperature
dry, chapped, or (25° C) and to protect from
irritated skin light.
- Avoid using other • Stop treatment, and
topical product on consult physician about
the same area as diagnosis if no improvement is
they may interfere seen within 2 wk of topical
with the effects or application.
the absorption of
the medicine
Sauders. (20). Nursing Drug Handbook, pages -