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She will present the recently solved crystal structures of Oskar and discuss activities of previously
uncharacterized protein domains. The molecular mechanisms that take place in and define the germ
plasm are poorly understood. Proceedings of the National Academy of Sciences 120: e2304385120.
Furthermore, she will address the molecular functions of Vasa, a germ-line specific DEAD-box RNA
helicase involved in the secondary piRNA pathway, and how a novel class of protein domains
regulates Vasa’s enzymatic activity. To segregate the germline from soma, during early development
many animals assemble a specialized cytoplasm, which is called germ plasm. The main research
focusses on understanding molecular mechanism underlying piRNA biogenesis and piRNA-mediated
silencing of transposon mRNAs, processes which are highly critical during gametogenesis and early
animal development.
Proceedings of the National Academy of Sciences 120: e2304385120. The main research focusses on
understanding molecular mechanism underlying piRNA biogenesis and piRNA-mediated silencing of
transposon mRNAs, processes which are highly critical during gametogenesis and early animal
development. Furthermore, she will address the molecular functions of Vasa, a germ-line specific
DEAD-box RNA helicase involved in the secondary piRNA pathway, and how a novel class of
protein domains regulates Vasa’s enzymatic activity. To segregate the germline from soma, during
early development many animals assemble a specialized cytoplasm, which is called germ plasm. The
molecular mechanisms that take place in and define the germ plasm are poorly understood. She will
present the recently solved crystal structures of Oskar and discuss activities of previously
uncharacterized protein domains.
The main research focusses on understanding molecular mechanism underlying piRNA biogenesis
and piRNA-mediated silencing of transposon mRNAs, processes which are highly critical during
gametogenesis and early animal development. To segregate the germline from soma, during early
development many animals assemble a specialized cytoplasm, which is called germ plasm. She will
present the recently solved crystal structures of Oskar and discuss activities of previously
uncharacterized protein domains. The molecular mechanisms that take place in and define the germ
plasm are poorly understood. Furthermore, she will address the molecular functions of Vasa, a germ-
line specific DEAD-box RNA helicase involved in the secondary piRNA pathway, and how a novel
class of protein domains regulates Vasa’s enzymatic activity. Proceedings of the National Academy
of Sciences 120: e2304385120.
She will present the recently solved crystal structures of Oskar and discuss activities of previously
uncharacterized protein domains. Furthermore, she will address the molecular functions of Vasa, a
germ-line specific DEAD-box RNA helicase involved in the secondary piRNA pathway, and how a
novel class of protein domains regulates Vasa’s enzymatic activity. Proceedings of the National
Academy of Sciences 120: e2304385120. The main research focusses on understanding molecular
mechanism underlying piRNA biogenesis and piRNA-mediated silencing of transposon mRNAs,
processes which are highly critical during gametogenesis and early animal development. The
molecular mechanisms that take place in and define the germ plasm are poorly understood. To
segregate the germline from soma, during early development many animals assemble a specialized
cytoplasm, which is called germ plasm.
To segregate the germline from soma, during early development many animals assemble a specialized
cytoplasm, which is called germ plasm. Furthermore, she will address the molecular functions of
Vasa, a germ-line specific DEAD-box RNA helicase involved in the secondary piRNA pathway, and
how a novel class of protein domains regulates Vasa’s enzymatic activity. Proceedings of the
National Academy of Sciences 120: e2304385120. The main research focusses on understanding
molecular mechanism underlying piRNA biogenesis and piRNA-mediated silencing of transposon
mRNAs, processes which are highly critical during gametogenesis and early animal development.
She will present the recently solved crystal structures of Oskar and discuss activities of previously
uncharacterized protein domains. The molecular mechanisms that take place in and define the germ
plasm are poorly understood.