Anti-infective agents Nursing Pharmacology “Seite oat a stow fee Anti-infective acti “ett na ty SES ht Seoaranoee tosis cat ae eras Seatac Ie ene acer HLS y Atintectve agents sees oe eee matunga “faassen sis i a oe Mechanisms of Action Some interfere wih DNA synthesis inthe el, leading to inabity to dvise and cet eat. Fluoroqunoiones workin tis way, thers ater the permesbilty ot con essential ea membrane to allow components to leak ou, causing eel decry Some antobiatcs, anteungals, ard Antiprotozoals werk inthe way, ‘Anti-infective activity Salted ron tree wah he bly ot tts forepocsceo ate Badergl «they cause the death of te cae bol Ha ant ‘iat te reat oS rae 1. Sant loa ate to pathogen weet Sting severe onc uth oe 2 ee ne “te san cotaResistance Ga et icdstongs Sia whng resistance (yp) Procueng an ow pital gM" at densest nang tg terra Wahepen sgl om ecu dg fn selvetranpen igo Rene "eentiteaten of te Pathogen 3 tosve sample fon oe ‘Senaitay ef tre Pa embinatien tery used tr several reasons: ‘may alow doctor use a smator ne each og 2 some age ae 2 serge, meaning more ‘ower when gen ‘Adverse reactions to antiinfective therapy “at 2 [Guertin tact - cong mae. vig. lone on pls, SiMe eae pa racine Resistance eat Sehr 3 Many microbial infectons are caused by "mote than one organist 4 Sometimes, tho combined eects ot ferent drugs delay’ the emergence ot fesitant strains, The is important 18 Malora ‘treatment Peluding some ‘Adverse reactions to anti- infective therapy “Ree tS nt ase Slo hea eat 5 Spercinsare rout pacian canAntibiotics, Aminoglycosides - used to treat serous infecons caused by gram-neatie teopenaa | amkacin Armin) shorter or and _ eae ity wee eta ranyen) sesamin ramen) otha, ‘3. sueptomycin-very toto the ih cranial ‘ene ad re, Used or Ts eaten. 2. Secoregeneraton - eeciveagaest ‘iaemopnigs evnzae | andNeisea Spates, They ate ess elective apst (Gam postive tata ‘amie: eal, aor, cetoxne 23 Thdgeneraon- more poor ans _garenogsve Eanes exon cata, eters Snipes Sskemamanetent Antibiotics ‘cephalosporins - sini openins in suc and acy. 1. Fis. gnaraton-efectve aganst sae gam poative bacteria that af afecea by fencin G afd and yar-negatve frei ike Ecol and Kebsele pneumoniae. xanpiescazli and cehalexn Trusegunclres - fave bond specu ot son au poten —ectheapi aide ano is atbaders hale Relate SSieeicies ome wanes ier spelen yes Sn nt wan tan 2 Monkemg betting ld omecute arene see